| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| TPTX | EVP & Chief Financial Officer | Aug 17, 2022 | Option Exercise | $76.00 | 29,778 | 2,263,128 | 0 | Aug 17, 2022, 04:31 PM |
| TPTX | EVP & Chief Financial Officer | Jul 27, 2022 | Sale | $74.94 | 1,183 | 88,654 | 28,700 | Jul 29, 2022, 04:18 PM |
| EPZM | Chief Financial Officer | Feb 04, 2021 | Sale | $11.21 | 1,021 | 11,445 | 53,465 | Feb 05, 2021, 04:40 PM |
| EPZM | Chief Financial Officer | Aug 20, 2020 | Option Exercise | $12.55 | 2,091 | 26,242 | 26,906 | Aug 21, 2020, 04:15 PM |
| EPZM | Chief Financial Officer | Jun 26, 2020 | Sale | $16.15 | 1,805 | 29,151 | 21,942 | Jun 30, 2020, 08:57 AM |
| EPZM | Chief Financial Officer | Mar 25, 2020 | Sale | $15.28 | 1,243 | 18,993 | 15,437 | Mar 26, 2020, 09:01 PM |
| EPZM | Chief Financial Officer | Jan 23, 2020 | Option Exercise | $26.72 | 1,698 | 45,371 | 3,302 | Jan 27, 2020, 09:15 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| TPTX | EVP & Chief Financial Officer | Aug 17, 2022 | Option Exercise | 2,263,128 |
| TPTX | EVP & Chief Financial Officer | Jul 27, 2022 | Sale | 88,654 |
| EPZM | Chief Financial Officer | Feb 04, 2021 | Sale | 11,445 |
| EPZM | Chief Financial Officer | Aug 20, 2020 | Option Exercise | 26,242 |
| EPZM | Chief Financial Officer | Jun 26, 2020 | Sale | 29,151 |
| EPZM | Chief Financial Officer | Mar 25, 2020 | Sale | 18,993 |
| EPZM | Chief Financial Officer | Jan 23, 2020 | Option Exercise | 45,371 |