| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| ARQT | 10% Owner | Aug 05, 2022 | Buy | $20.00 | 250,000 | 5,000,000 | 8,684,232 | Aug 09, 2022, 04:34 PM |
| ALPN | 10% Owner | Feb 11, 2022 | Buy | $7.10 | 112,665 | 799,989 | 1,484,115 | Feb 15, 2022, 05:00 PM |
| ARQT | 10% Owner | Feb 04, 2020 | Buy | $17.00 | 500,000 | 8,500,000 | 10,542,790 | Feb 06, 2020, 10:29 AM |
| ETTX | 10% Owner | Jan 09, 2020 | Sale | $5.00 | 50,000 | 250,010 | 1,299,953 | Jan 13, 2020, 10:47 AM |
| ALPN | 10% Owner | Jan 18, 2019 | Buy | $5.37 | 372,439 | 1,999,997 | 2,571,450 | Jan 22, 2019, 05:14 PM |
| ETTX | 10% Owner | Sep 28, 2018 | Buy | $15.00 | 375,887 | 5,638,305 | 1,349,953 | Oct 02, 2018, 09:38 PM |
| APTX | 10% Owner | Jun 25, 2018 | Buy | $16.00 | 150,000 | 2,400,000 | 3,190,079 | Jun 26, 2018, 04:56 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| ARQT | 10% Owner | Aug 05, 2022 | Buy | 5,000,000 |
| ALPN | 10% Owner | Feb 11, 2022 | Buy | 799,989 |
| ARQT | 10% Owner | Feb 04, 2020 | Buy | 8,500,000 |
| ETTX | 10% Owner | Jan 09, 2020 | Sale | 250,010 |
| ALPN | 10% Owner | Jan 18, 2019 | Buy | 1,999,997 |
| ETTX | 10% Owner | Sep 28, 2018 | Buy | 5,638,305 |
| APTX | 10% Owner | Jun 25, 2018 | Buy | 2,400,000 |