| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| CRVS | Director | May 15, 2023 | Buy | $2.45 | 10,000 | 24,500 | 10,000 | May 16, 2023, 04:54 PM |
| OCRX | President and CEO | Dec 11, 2017 | Option Exercise | $1.52 | 300,000 | 456,000 | 0 | Dec 11, 2017, 03:25 PM |
| OCRX | President and CEO | Dec 07, 2016 | Buy | $2.14 | 7,000 | 14,980 | 70,000 | Dec 08, 2016, 04:18 PM |
| OCRX | President and CEO | Mar 04, 2016 | Buy | $3.19 | 3,000 | 9,570 | 63,000 | Mar 07, 2016, 08:08 AM |
| OCRX | President and CEO | Jan 22, 2016 | Buy | $2.38 | 10,000 | 23,800 | 60,000 | Jan 25, 2016, 05:19 PM |
| OCRX | President and CEO | Jan 15, 2016 | Buy | $2.08 | 10,000 | 20,800 | 50,000 | Jan 19, 2016, 08:14 AM |
| OCRX | President and CEO | May 06, 2015 | Buy | $3.73 | 30,000 | 111,900 | 40,000 | May 06, 2015, 06:03 PM |
| OCRX | President and CEO | Jul 11, 2014 | Buy | $5.93 | 10,000 | 59,280 | 10,000 | Jul 15, 2014, 04:05 PM |
| TSRX | 10% Owner | Aug 06, 2010 | Option Exercise | $4.38 | 744,496 | 3,260,893 | 2,321,310 | Aug 10, 2010, 01:52 PM |
| TSRX | 10% Owner | Aug 06, 2010 | Buy | $5.00 | 1,227,333 | 6,136,665 | 3,548,643 | Aug 10, 2010, 01:52 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| CRVS | Director | May 15, 2023 | Buy | 24,500 |
| OCRX | President and CEO | Dec 11, 2017 | Option Exercise | 456,000 |
| OCRX | President and CEO | Dec 07, 2016 | Buy | 14,980 |
| OCRX | President and CEO | Mar 04, 2016 | Buy | 9,570 |
| OCRX | President and CEO | Jan 22, 2016 | Buy | 23,800 |
| OCRX | President and CEO | Jan 15, 2016 | Buy | 20,800 |
| OCRX | President and CEO | May 06, 2015 | Buy | 111,900 |
| OCRX | President and CEO | Jul 11, 2014 | Buy | 59,280 |
| TSRX | 10% Owner | Aug 06, 2010 | Option Exercise | 3,260,893 |
| TSRX | 10% Owner | Aug 06, 2010 | Buy | 6,136,665 |