| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| SRRA | Director | Jul 01, 2022 | Option Exercise | $55.00 | 1,650 | 90,750 | 0 | Jul 01, 2022, 04:38 PM |
| EPZM | Director | Mar 16, 2020 | Option Exercise | $9.33 | 12,500 | 116,625 | 12,500 | Mar 18, 2020, 04:30 PM |
| SRRA | Director | Dec 10, 2018 | Buy | $1.64 | 66,000 | 108,240 | 66,000 | Dec 11, 2018, 05:38 PM |
| CLVS | See Remarks | Jan 16, 2015 | Sale | $65.88 | 79,700 | 5,250,396 | 151,095 | Jan 21, 2015, 09:09 PM |
| CLVS | See Remarks | Jan 15, 2015 | Sale | $65.00 | 300 | 19,500 | 181,619 | Jan 21, 2015, 09:09 PM |
| CLVS | See Remarks | Jan 16, 2015 | Sale | $65.64 | 79,700 | 5,231,793 | 151,095 | Jan 20, 2015, 09:11 PM |
| CLVS | See Remarks | Jan 15, 2015 | Sale | $65.00 | 300 | 19,500 | 181,619 | Jan 20, 2015, 09:11 PM |
| CLVS | See Remarks | Jun 05, 2013 | Sale | $68.54 | 22,594 | 1,548,683 | 21,894 | Jun 07, 2013, 05:04 PM |
| CLVS | See Remarks | Nov 21, 2011 | Buy | $13.00 | 3,846 | 49,998 | 223,004 | Nov 21, 2011, 02:11 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| SRRA | Director | Jul 01, 2022 | Option Exercise | 90,750 |
| EPZM | Director | Mar 16, 2020 | Option Exercise | 116,625 |
| SRRA | Director | Dec 10, 2018 | Buy | 108,240 |
| CLVS | See Remarks | Jan 16, 2015 | Sale | 5,250,396 |
| CLVS | See Remarks | Jan 15, 2015 | Sale | 19,500 |
| CLVS | See Remarks | Jan 16, 2015 | Sale | 5,231,793 |
| CLVS | See Remarks | Jan 15, 2015 | Sale | 19,500 |
| CLVS | See Remarks | Jun 05, 2013 | Sale | 1,548,683 |
| CLVS | See Remarks | Nov 21, 2011 | Buy | 49,998 |