| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| NBRV | Director | Aug 02, 2022 | Sale | $0.19 | 11,341 | 2,156 | 10,384 | Aug 04, 2022, 06:24 PM |
| NBRV | Director | Aug 02, 2021 | Sale | $1.20 | 1,125 | 1,350 | 21,725 | Aug 04, 2021, 09:07 PM |
| NBRV | Director | Jul 31, 2018 | Buy | $2.75 | 36,000 | 99,000 | 36,000 | Aug 02, 2018, 05:51 PM |
| CDTX | Director | Apr 20, 2015 | Buy | $16.00 | 3,000 | 48,000 | 3,000 | Apr 21, 2015, 03:29 PM |
| SNTS | Director | Jun 03, 2013 | Option Exercise | $3.00 | 8,000 | 24,000 | 8,000 | Jun 04, 2013, 06:22 PM |
| SNTS | Director | Jun 03, 2013 | Sale | $21.34 | 8,000 | 170,726 | 0 | Jun 04, 2013, 06:22 PM |
| SNTS | Director | May 01, 2013 | Option Exercise | $3.00 | 8,000 | 24,000 | 8,000 | May 02, 2013, 04:24 PM |
| SNTS | Director | May 01, 2013 | Sale | $17.88 | 8,000 | 143,047 | 0 | May 02, 2013, 04:24 PM |
| SNTS | Director | Apr 01, 2013 | Option Exercise | $2.09 | 8,000 | 16,720 | 8,000 | Apr 02, 2013, 05:26 PM |
| SNTS | Director | Apr 01, 2013 | Sale | $17.47 | 8,000 | 139,774 | 0 | Apr 02, 2013, 05:26 PM |
| SNTS | Director | Mar 01, 2013 | Option Exercise | $1.18 | 8,000 | 9,440 | 8,000 | Mar 04, 2013, 08:07 PM |
| SNTS | Director | Mar 01, 2013 | Sale | $13.37 | 8,000 | 106,954 | 0 | Mar 04, 2013, 08:07 PM |
| SNTS | Director | Feb 01, 2013 | Option Exercise | $1.18 | 8,000 | 9,440 | 8,000 | Feb 04, 2013, 04:41 PM |
| SNTS | Director | Feb 01, 2013 | Sale | $13.28 | 8,000 | 106,245 | 0 | Feb 04, 2013, 04:41 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| NBRV | Director | Aug 02, 2022 | Sale | 2,156 |
| NBRV | Director | Aug 02, 2021 | Sale | 1,350 |
| NBRV | Director | Jul 31, 2018 | Buy | 99,000 |
| CDTX | Director | Apr 20, 2015 | Buy | 48,000 |
| SNTS | Director | Jun 03, 2013 | Option Exercise | 24,000 |
| SNTS | Director | Jun 03, 2013 | Sale | 170,726 |
| SNTS | Director | May 01, 2013 | Option Exercise | 24,000 |
| SNTS | Director | May 01, 2013 | Sale | 143,047 |
| SNTS | Director | Apr 01, 2013 | Option Exercise | 16,720 |
| SNTS | Director | Apr 01, 2013 | Sale | 139,774 |
| SNTS | Director | Mar 01, 2013 | Option Exercise | 9,440 |
| SNTS | Director | Mar 01, 2013 | Sale | 106,954 |
| SNTS | Director | Feb 01, 2013 | Option Exercise | 9,440 |
| SNTS | Director | Feb 01, 2013 | Sale | 106,245 |