| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| BMRN | Chief Executive Officer | Aug 08, 2023 | Sale | $88.29 | 6,000 | 529,740 | 422,732 | Aug 09, 2023, 07:05 PM |
| BMRN | Chief Executive Officer | Aug 07, 2023 | Sale | $88.10 | 4,000 | 352,400 | 428,732 | Aug 09, 2023, 07:05 PM |
| BMRN | Chief Executive Officer | May 12, 2023 | Option Exercise | $93.93 | 39,981 | 3,755,415 | 466,376 | May 16, 2023, 05:22 PM |
| BMRN | Chief Executive Officer | May 12, 2023 | Option Exercise | $67.81 | 46,500 | 3,153,165 | 472,713 | May 16, 2023, 05:22 PM |
| BMRN | Chief Executive Officer | May 11, 2023 | Option Exercise | $67.81 | 30,000 | 2,034,300 | 456,213 | May 15, 2023, 04:58 PM |
| BMRN | Chief Executive Officer | May 11, 2023 | Sale | $94.67 | 30,000 | 2,840,226 | 431,774 | May 15, 2023, 04:58 PM |
| BMRN | Chief Executive Officer | Apr 28, 2023 | Option Exercise | $66.88 | 317 | 21,201 | 426,213 | May 11, 2023, 05:04 PM |
| BMRN | Chief Executive Officer | May 09, 2023 | Option Exercise | $67.81 | 30,000 | 2,034,300 | 456,213 | May 11, 2023, 05:04 PM |
| BMRN | Chief Executive Officer | May 10, 2023 | Option Exercise | $67.81 | 30,000 | 2,034,300 | 456,213 | May 11, 2023, 05:04 PM |
| BMRN | Chief Executive Officer | May 10, 2023 | Sale | $94.85 | 30,000 | 2,845,397 | 434,760 | May 11, 2023, 05:04 PM |
| BMRN | Chief Executive Officer | May 09, 2023 | Sale | $94.93 | 30,000 | 2,847,973 | 442,587 | May 11, 2023, 05:04 PM |
| BMRN | Chief Executive Officer | Apr 10, 2023 | Option Exercise | $67.81 | 10,000 | 678,100 | 435,896 | Apr 12, 2023, 04:08 PM |
| BMRN | Chief Executive Officer | Apr 10, 2023 | Sale | $99.56 | 10,000 | 995,600 | 425,896 | Apr 12, 2023, 04:08 PM |
| BMRN | Chief Executive Officer | Apr 06, 2023 | Option Exercise | $67.81 | 10,000 | 678,100 | 435,896 | Apr 10, 2023, 07:00 PM |
| BMRN | Chief Executive Officer | Apr 06, 2023 | Sale | $96.13 | 10,000 | 961,300 | 425,896 | Apr 10, 2023, 07:00 PM |
| BMRN | Chief Executive Officer | Mar 15, 2023 | Option Exercise | $87.74 | 9,437 | 828,002 | 514,519 | Mar 17, 2023, 09:22 PM |
| BMRN | Chief Executive Officer | Mar 16, 2023 | Option Exercise | $93.41 | 88,623 | 8,278,275 | 425,896 | Mar 17, 2023, 09:22 PM |
| BMRN | Chief Executive Officer | Mar 13, 2023 | Option Exercise | $67.81 | 8,000 | 542,480 | 495,856 | Mar 14, 2023, 07:40 PM |
| BMRN | Chief Executive Officer | Mar 10, 2023 | Option Exercise | $67.81 | 15,000 | 1,017,150 | 502,856 | Mar 14, 2023, 07:40 PM |
| BMRN | Chief Executive Officer | Mar 13, 2023 | Sale | $90.45 | 8,000 | 723,600 | 487,856 | Mar 14, 2023, 07:40 PM |
| BMRN | Chief Executive Officer | Mar 10, 2023 | Sale | $92.28 | 15,000 | 1,384,200 | 487,856 | Mar 14, 2023, 07:40 PM |
| BMRN | Chief Executive Officer | Feb 10, 2023 | Option Exercise | $67.81 | 15,000 | 1,017,150 | 335,324 | Feb 14, 2023, 08:00 PM |
| BMRN | Chief Executive Officer | Feb 13, 2023 | Option Exercise | $67.81 | 6,000 | 406,860 | 326,324 | Feb 14, 2023, 08:00 PM |
| BMRN | Chief Executive Officer | Feb 10, 2023 | Sale | $110.11 | 15,000 | 1,651,650 | 320,324 | Feb 14, 2023, 08:00 PM |
| BMRN | Chief Executive Officer | Feb 13, 2023 | Sale | $109.15 | 6,000 | 654,900 | 320,324 | Feb 14, 2023, 08:00 PM |
| BMRN | Chief Executive Officer | Jan 17, 2023 | Option Exercise | $67.81 | 10,000 | 678,100 | 330,424 | Jan 18, 2023, 09:41 PM |
| BMRN | Chief Executive Officer | Jan 13, 2023 | Option Exercise | $67.81 | 10,000 | 678,100 | 330,424 | Jan 18, 2023, 09:41 PM |
| BMRN | Chief Executive Officer | Jan 17, 2023 | Sale | $111.55 | 10,000 | 1,115,500 | 320,424 | Jan 18, 2023, 09:41 PM |
| BMRN | Chief Executive Officer | Jan 13, 2023 | Sale | $112.25 | 10,000 | 1,122,500 | 320,424 | Jan 18, 2023, 09:41 PM |
| BMRN | Chief Executive Officer | Dec 13, 2022 | Sale | $106.89 | 1,000 | 106,890 | 320,424 | Dec 15, 2022, 04:43 PM |
| BMRN | Chief Executive Officer | Nov 02, 2022 | Option Exercise | $86.12 | 100 | 8,612 | 322,924 | Dec 06, 2022, 09:09 PM |
| BMRN | Chief Executive Officer | Dec 02, 2022 | Sale | $103.98 | 1,500 | 155,967 | 322,453 | Dec 06, 2022, 09:09 PM |
| BMRN | Chief Executive Officer | Oct 31, 2022 | Sale | $86.55 | 1,500 | 129,825 | 322,824 | Nov 01, 2022, 08:38 PM |
| BMRN | Chief Executive Officer | Oct 14, 2022 | Sale | $89.89 | 4,000 | 359,560 | 324,324 | Oct 18, 2022, 08:01 PM |
| BMRN | Chief Executive Officer | Aug 15, 2022 | Sale | $95.21 | 3,000 | 285,630 | 328,324 | Aug 16, 2022, 07:36 PM |
| BMRN | Chief Executive Officer | Aug 12, 2022 | Sale | $94.75 | 4,000 | 379,000 | 331,324 | Aug 16, 2022, 07:36 PM |
| BMRN | Chief Executive Officer | Apr 29, 2022 | Option Exercise | $62.41 | 341 | 21,281 | 335,324 | May 09, 2022, 09:29 PM |
| BMRN | Chief Executive Officer | May 06, 2022 | Option Exercise | $37.46 | 20,000 | 749,200 | 355,324 | May 09, 2022, 09:29 PM |
| BMRN | Chief Executive Officer | May 05, 2022 | Option Exercise | $37.46 | 10,000 | 374,600 | 345,324 | May 09, 2022, 09:29 PM |
| BMRN | Chief Executive Officer | May 06, 2022 | Sale | $81.00 | 20,000 | 1,620,000 | 335,324 | May 09, 2022, 09:29 PM |
| BMRN | Chief Executive Officer | May 05, 2022 | Sale | $84.14 | 10,000 | 841,400 | 335,324 | May 09, 2022, 09:29 PM |
| BMRN | Chief Executive Officer | Apr 29, 2022 | Option Exercise | $37.46 | 5,000 | 187,300 | 339,983 | May 02, 2022, 09:27 PM |
| BMRN | Chief Executive Officer | Apr 28, 2022 | Option Exercise | $37.46 | 20,000 | 749,200 | 354,983 | May 02, 2022, 09:27 PM |
| BMRN | Chief Executive Officer | Apr 28, 2022 | Sale | $83.79 | 20,000 | 1,675,800 | 334,983 | May 02, 2022, 09:27 PM |
| BMRN | Chief Executive Officer | Apr 29, 2022 | Sale | $81.95 | 5,000 | 409,750 | 334,983 | May 02, 2022, 09:27 PM |
| BMRN | Chief Executive Officer | Apr 18, 2022 | Option Exercise | $37.46 | 20,000 | 749,200 | 354,983 | Apr 20, 2022, 08:20 PM |
| BMRN | Chief Executive Officer | Apr 18, 2022 | Sale | $81.91 | 20,000 | 1,638,200 | 334,983 | Apr 20, 2022, 08:20 PM |
| BMRN | Chief Executive Officer | Apr 14, 2022 | Option Exercise | $37.46 | 10,000 | 374,600 | 344,983 | Apr 18, 2022, 09:46 PM |
| BMRN | Chief Executive Officer | Apr 14, 2022 | Sale | $83.66 | 10,000 | 836,600 | 334,983 | Apr 18, 2022, 09:46 PM |
| BMRN | Chief Executive Officer | Mar 16, 2022 | Option Exercise | $80.72 | 5,560 | 448,803 | 334,983 | Mar 17, 2022, 09:18 PM |
| BMRN | Chief Executive Officer | Mar 15, 2022 | Option Exercise | $78.27 | 38,306 | 2,998,210 | 340,543 | Mar 17, 2022, 09:18 PM |
| BMRN | Chief Executive Officer | Mar 11, 2022 | Option Exercise | $37.46 | 15,000 | 561,900 | 353,569 | Mar 14, 2022, 08:44 PM |
| BMRN | Chief Executive Officer | Mar 10, 2022 | Option Exercise | $37.46 | 15,000 | 561,900 | 353,569 | Mar 14, 2022, 08:44 PM |
| BMRN | Chief Executive Officer | Mar 11, 2022 | Sale | $77.81 | 15,000 | 1,167,150 | 338,569 | Mar 14, 2022, 08:44 PM |
| BMRN | Chief Executive Officer | Mar 10, 2022 | Sale | $77.57 | 15,000 | 1,163,550 | 338,569 | Mar 14, 2022, 08:44 PM |
| BMRN | Chief Executive Officer | Dec 21, 2021 | Option Exercise | $89.22 | 100 | 8,922 | 303,789 | Jan 14, 2022, 08:45 PM |
| BMRN | Chief Executive Officer | Jan 13, 2022 | Option Exercise | $37.46 | 5,000 | 187,300 | 308,789 | Jan 14, 2022, 08:45 PM |
| BMRN | Chief Executive Officer | Jan 12, 2022 | Option Exercise | $37.46 | 5,000 | 187,300 | 308,789 | Jan 14, 2022, 08:45 PM |
| BMRN | Chief Executive Officer | Jan 13, 2022 | Sale | $87.86 | 5,000 | 439,300 | 303,789 | Jan 14, 2022, 08:45 PM |
| BMRN | Chief Executive Officer | Jan 12, 2022 | Sale | $89.00 | 5,000 | 445,000 | 303,789 | Jan 14, 2022, 08:45 PM |
| BMRN | Chief Executive Officer | Dec 16, 2021 | Option Exercise | $37.46 | 6,000 | 224,760 | 309,689 | Dec 17, 2021, 07:03 PM |
| BMRN | Chief Executive Officer | Dec 15, 2021 | Option Exercise | $37.46 | 6,000 | 224,760 | 309,689 | Dec 17, 2021, 07:03 PM |
| BMRN | Chief Executive Officer | Dec 15, 2021 | Sale | $82.71 | 6,000 | 496,260 | 303,689 | Dec 17, 2021, 07:03 PM |
| BMRN | Chief Executive Officer | Dec 16, 2021 | Sale | $84.68 | 6,000 | 508,080 | 303,689 | Dec 17, 2021, 07:03 PM |
| BMRN | Chief Executive Officer | Sep 09, 2021 | Option Exercise | $78.77 | 50 | 3,938 | 305,889 | Dec 02, 2021, 09:42 PM |
| BMRN | Chief Executive Officer | Dec 01, 2021 | Sale | $87.22 | 1,500 | 130,832 | 304,389 | Dec 02, 2021, 09:42 PM |
| BMRN | Chief Executive Officer | Oct 20, 2021 | Option Exercise | $37.46 | 1,000 | 37,460 | 305,839 | Oct 22, 2021, 04:36 PM |
| BMRN | Chief Executive Officer | Jun 21, 2021 | Option Exercise | $37.46 | 1,000 | 37,460 | 304,839 | Jun 23, 2021, 05:04 PM |
| BMRN | Chief Executive Officer | May 10, 2021 | Option Exercise | $26.49 | 8,513 | 225,509 | 312,352 | May 12, 2021, 07:21 PM |
| BMRN | Chief Executive Officer | May 10, 2021 | Sale | $77.29 | 8,513 | 657,970 | 303,839 | May 12, 2021, 07:21 PM |
| BMRN | Chief Executive Officer | Apr 30, 2021 | Option Exercise | $62.41 | 341 | 21,281 | 303,839 | May 10, 2021, 09:07 PM |
| BMRN | Chief Executive Officer | May 07, 2021 | Option Exercise | $26.49 | 25,000 | 662,250 | 328,839 | May 10, 2021, 09:07 PM |
| BMRN | Chief Executive Officer | May 06, 2021 | Option Exercise | $26.49 | 25,000 | 662,250 | 328,839 | May 10, 2021, 09:07 PM |
| BMRN | Chief Executive Officer | May 07, 2021 | Sale | $78.12 | 25,000 | 1,953,121 | 313,283 | May 10, 2021, 09:07 PM |
| BMRN | Chief Executive Officer | May 06, 2021 | Sale | $78.29 | 25,000 | 1,957,199 | 314,014 | May 10, 2021, 09:07 PM |
| BMRN | Chief Executive Officer | Apr 23, 2021 | Option Exercise | $26.49 | 10,000 | 264,900 | 312,498 | Apr 26, 2021, 08:44 PM |
| BMRN | Chief Executive Officer | Apr 22, 2021 | Option Exercise | $26.49 | 10,000 | 264,900 | 312,498 | Apr 26, 2021, 08:44 PM |
| BMRN | Chief Executive Officer | Apr 23, 2021 | Sale | $79.34 | 10,000 | 793,400 | 302,498 | Apr 26, 2021, 08:44 PM |
| BMRN | Chief Executive Officer | Apr 22, 2021 | Sale | $78.91 | 10,000 | 789,100 | 302,498 | Apr 26, 2021, 08:44 PM |
| BMRN | Chief Executive Officer | Mar 22, 2021 | Option Exercise | $78.52 | 5,519 | 433,352 | 302,498 | Mar 23, 2021, 08:50 PM |
| BMRN | Chief Executive Officer | Mar 15, 2021 | Option Exercise | $78.39 | 23,426 | 1,836,364 | 313,576 | Mar 17, 2021, 09:24 PM |
| BMRN | Chief Executive Officer | Mar 16, 2021 | Option Exercise | $77.21 | 5,559 | 429,210 | 308,017 | Mar 17, 2021, 09:24 PM |
| BMRN | Chief Executive Officer | Mar 04, 2021 | Option Exercise | $77.94 | 100 | 7,794 | 295,652 | Mar 15, 2021, 08:26 PM |
| BMRN | Chief Executive Officer | Mar 12, 2021 | Option Exercise | $26.49 | 7,000 | 185,430 | 302,652 | Mar 15, 2021, 08:26 PM |
| BMRN | Chief Executive Officer | Mar 11, 2021 | Option Exercise | $26.49 | 7,000 | 185,430 | 302,652 | Mar 15, 2021, 08:26 PM |
| BMRN | Chief Executive Officer | Mar 12, 2021 | Sale | $77.10 | 7,000 | 539,700 | 295,652 | Mar 15, 2021, 08:26 PM |
| BMRN | Chief Executive Officer | Mar 11, 2021 | Sale | $77.68 | 7,000 | 543,760 | 295,652 | Mar 15, 2021, 08:26 PM |
| BMRN | Chief Executive Officer | Feb 19, 2021 | Option Exercise | $26.49 | 7,000 | 185,430 | 302,552 | Feb 22, 2021, 08:38 PM |
| BMRN | Chief Executive Officer | Feb 19, 2021 | Sale | $83.58 | 7,000 | 585,060 | 295,552 | Feb 22, 2021, 08:38 PM |
| BMRN | Chief Executive Officer | Feb 18, 2021 | Option Exercise | $26.49 | 7,000 | 185,430 | 302,552 | Feb 19, 2021, 09:22 PM |
| BMRN | Chief Executive Officer | Feb 18, 2021 | Sale | $85.08 | 7,000 | 595,560 | 295,552 | Feb 19, 2021, 09:22 PM |
| BMRN | Chief Executive Officer | Feb 17, 2021 | Option Exercise | $26.49 | 8,000 | 211,920 | 303,552 | Feb 18, 2021, 09:45 PM |
| BMRN | Chief Executive Officer | Feb 17, 2021 | Sale | $84.54 | 8,000 | 676,320 | 295,552 | Feb 18, 2021, 09:45 PM |
| BMRN | Chief Executive Officer | Jan 29, 2021 | Option Exercise | $26.49 | 8,334 | 220,768 | 303,886 | Feb 01, 2021, 07:00 PM |
| BMRN | Chief Executive Officer | Jan 28, 2021 | Option Exercise | $26.49 | 8,333 | 220,741 | 303,885 | Feb 01, 2021, 07:00 PM |
| BMRN | Chief Executive Officer | Jan 28, 2021 | Sale | $82.91 | 8,333 | 690,889 | 295,552 | Feb 01, 2021, 07:00 PM |
| BMRN | Chief Executive Officer | Jan 29, 2021 | Sale | $82.67 | 8,334 | 688,972 | 295,552 | Feb 01, 2021, 07:00 PM |
| BMRN | Chief Executive Officer | Jan 27, 2021 | Option Exercise | $26.49 | 8,333 | 220,741 | 303,885 | Jan 28, 2021, 07:35 PM |
| BMRN | Chief Executive Officer | Jan 27, 2021 | Sale | $85.49 | 8,333 | 712,388 | 295,552 | Jan 28, 2021, 07:35 PM |
| INCY | Director | Dec 31, 2020 | Option Exercise | $86.98 | 275 | 23,920 | 8,921 | Jan 05, 2021, 04:48 PM |
| BMRN | Chief Executive Officer | Dec 28, 2020 | Sale | $88.77 | 1,500 | 133,155 | 297,052 | Dec 30, 2020, 08:02 PM |
| BMRN | Chief Executive Officer | Dec 29, 2020 | Sale | $88.18 | 1,500 | 132,270 | 295,552 | Dec 30, 2020, 08:02 PM |
| INCY | Director | Nov 10, 2020 | Sale | $83.00 | 798 | 66,234 | 8,646 | Nov 12, 2020, 04:41 PM |
| INCY | Director | Sep 30, 2020 | Option Exercise | $89.74 | 254 | 22,794 | 9,444 | Oct 01, 2020, 04:40 PM |
| INCY | Director | Jun 30, 2020 | Option Exercise | $103.97 | 208 | 21,626 | 9,190 | Jul 01, 2020, 04:45 PM |
| BMRN | Chief Executive Officer | May 08, 2020 | Option Exercise | $21.51 | 20,000 | 430,200 | 318,552 | May 12, 2020, 01:51 PM |
| BMRN | Chief Executive Officer | May 08, 2020 | Sale | $91.72 | 20,000 | 1,834,400 | 298,552 | May 12, 2020, 01:51 PM |
| BMRN | Chief Executive Officer | Apr 30, 2020 | Option Exercise | $62.59 | 339 | 21,217 | 298,552 | May 05, 2020, 07:22 PM |
| BMRN | Chief Executive Officer | May 04, 2020 | Option Exercise | $21.51 | 5,000 | 107,550 | 303,552 | May 05, 2020, 07:22 PM |
| BMRN | Chief Executive Officer | May 01, 2020 | Option Exercise | $21.51 | 4,000 | 86,040 | 302,552 | May 05, 2020, 07:22 PM |
| BMRN | Chief Executive Officer | May 04, 2020 | Sale | $88.00 | 5,000 | 440,000 | 298,552 | May 05, 2020, 07:22 PM |
| BMRN | Chief Executive Officer | May 01, 2020 | Sale | $89.38 | 4,000 | 357,520 | 298,552 | May 05, 2020, 07:22 PM |
| BMRN | Chief Executive Officer | Apr 28, 2020 | Option Exercise | $21.51 | 20,000 | 430,200 | 318,213 | Apr 29, 2020, 07:40 PM |
| BMRN | Chief Executive Officer | Apr 27, 2020 | Option Exercise | $21.51 | 20,000 | 430,200 | 318,213 | Apr 29, 2020, 07:40 PM |
| BMRN | Chief Executive Officer | Apr 27, 2020 | Sale | $97.73 | 20,000 | 1,954,600 | 298,213 | Apr 29, 2020, 07:40 PM |
| BMRN | Chief Executive Officer | Apr 28, 2020 | Sale | $97.58 | 20,000 | 1,951,600 | 298,213 | Apr 29, 2020, 07:40 PM |
| BMRN | Chief Executive Officer | Apr 09, 2020 | Option Exercise | $21.51 | 10,000 | 215,100 | 308,213 | Apr 13, 2020, 06:24 PM |
| BMRN | Chief Executive Officer | Apr 09, 2020 | Sale | $79.06 | 10,000 | 790,600 | 298,213 | Apr 13, 2020, 06:24 PM |
| BMRN | Chief Executive Officer | Apr 07, 2020 | Option Exercise | $26.49 | 1,000 | 26,490 | 298,213 | Apr 08, 2020, 08:54 PM |
| INCY | Director | Mar 31, 2020 | Option Exercise | $73.23 | 236 | 17,282 | 7,700 | Apr 02, 2020, 04:55 PM |
| BMRN | Chief Executive Officer | Mar 20, 2020 | Option Exercise | $73.05 | 13,128 | 959,000 | 297,213 | Mar 24, 2020, 08:42 PM |
| BMRN | Chief Executive Officer | Mar 13, 2020 | Option Exercise | $84.50 | 30,952 | 2,615,444 | 265,491 | Mar 17, 2020, 09:08 PM |
| BMRN | Chief Executive Officer | Mar 03, 2020 | Option Exercise | $94.39 | 30 | 2,832 | 296,443 | Mar 11, 2020, 09:01 PM |
| BMRN | Chief Executive Officer | Mar 09, 2020 | Option Exercise | $21.51 | 10,000 | 215,100 | 306,443 | Mar 11, 2020, 09:01 PM |
| BMRN | Chief Executive Officer | Mar 09, 2020 | Sale | $89.52 | 10,000 | 895,200 | 296,443 | Mar 11, 2020, 09:01 PM |
| BMRN | Chief Executive Officer | Feb 03, 2020 | Option Exercise | $21.51 | 10,000 | 215,100 | 338,530 | Feb 05, 2020, 08:38 PM |
| BMRN | Chief Executive Officer | Feb 03, 2020 | Sale | $83.50 | 10,000 | 835,000 | 328,530 | Feb 05, 2020, 08:38 PM |
| BMRN | Chief Executive Officer | Jan 30, 2020 | Option Exercise | $21.51 | 1,000 | 21,510 | 328,530 | Feb 03, 2020, 07:30 PM |
| BMRN | Chief Executive Officer | Jan 14, 2020 | Option Exercise | $21.51 | 8,000 | 172,080 | 335,530 | Jan 16, 2020, 08:00 PM |
| BMRN | Chief Executive Officer | Jan 14, 2020 | Sale | $87.95 | 8,000 | 703,600 | 327,530 | Jan 16, 2020, 08:00 PM |
| BMRN | Chief Executive Officer | Jan 07, 2020 | Option Exercise | $21.51 | 3,000 | 64,530 | 330,530 | Jan 09, 2020, 04:44 PM |
| BMRN | Chief Executive Officer | Jan 08, 2020 | Option Exercise | $21.51 | 4,000 | 86,040 | 331,530 | Jan 09, 2020, 04:44 PM |
| BMRN | Chief Executive Officer | Jan 08, 2020 | Sale | $84.92 | 4,000 | 339,680 | 327,530 | Jan 09, 2020, 04:44 PM |
| BMRN | Chief Executive Officer | Jan 07, 2020 | Sale | $84.46 | 3,000 | 253,380 | 327,530 | Jan 09, 2020, 04:44 PM |
| INCY | Director | Dec 31, 2019 | Option Exercise | $87.32 | 190 | 16,591 | 7,464 | Jan 03, 2020, 04:05 PM |
| BMRN | Chief Executive Officer | Dec 27, 2019 | Option Exercise | $21.51 | 5,000 | 107,550 | 332,530 | Dec 30, 2019, 07:27 PM |
| BMRN | Chief Executive Officer | Dec 26, 2019 | Option Exercise | $21.51 | 3,000 | 64,530 | 330,530 | Dec 30, 2019, 07:27 PM |
| BMRN | Chief Executive Officer | Dec 27, 2019 | Sale | $86.16 | 5,000 | 430,800 | 327,530 | Dec 30, 2019, 07:27 PM |
| BMRN | Chief Executive Officer | Dec 26, 2019 | Sale | $86.43 | 3,000 | 259,290 | 327,530 | Dec 30, 2019, 07:27 PM |
| BMRN | Chief Executive Officer | Nov 11, 2019 | Option Exercise | $75.38 | 10 | 754 | 327,080 | Nov 26, 2019, 01:34 PM |
| BMRN | Chief Executive Officer | Nov 22, 2019 | Option Exercise | $21.51 | 10,000 | 215,100 | 337,080 | Nov 26, 2019, 01:34 PM |
| BMRN | Chief Executive Officer | Nov 22, 2019 | Sale | $77.60 | 10,000 | 776,000 | 327,080 | Nov 26, 2019, 01:34 PM |
| BMRN | Chief Executive Officer | Oct 25, 2019 | Option Exercise | $21.51 | 5,000 | 107,550 | 332,520 | Oct 29, 2019, 07:16 PM |
| BMRN | Chief Executive Officer | Oct 25, 2019 | Sale | $69.55 | 5,000 | 347,750 | 327,520 | Oct 29, 2019, 07:16 PM |
| INCY | Director | Sep 30, 2019 | Option Exercise | $74.23 | 219 | 16,256 | 7,274 | Oct 02, 2019, 04:03 PM |
| BMRN | Chief Executive Officer | Sep 27, 2019 | Option Exercise | $21.51 | 1,000 | 21,510 | 327,520 | Sep 30, 2019, 08:16 PM |
| INCY | Director | Aug 02, 2019 | Sale | $84.73 | 377 | 31,943 | 7,055 | Aug 05, 2019, 04:36 PM |
| INCY | Director | Aug 01, 2019 | Sale | $85.16 | 1,347 | 114,711 | 7,432 | Aug 05, 2019, 04:36 PM |
| INCY | Director | Jun 28, 2019 | Option Exercise | $84.96 | 195 | 16,567 | 8,779 | Jul 02, 2019, 04:23 PM |
| BMRN | Chief Executive Officer | May 10, 2019 | Option Exercise | $14.39 | 10,000 | 143,900 | 336,520 | May 14, 2019, 07:15 PM |
| BMRN | Chief Executive Officer | May 10, 2019 | Sale | $82.52 | 10,000 | 825,193 | 326,520 | May 14, 2019, 07:15 PM |
| BMRN | Chief Executive Officer | May 09, 2019 | Option Exercise | $14.39 | 4,000 | 57,560 | 330,520 | May 13, 2019, 07:08 PM |
| BMRN | Chief Executive Officer | May 09, 2019 | Sale | $81.97 | 4,000 | 327,888 | 326,520 | May 13, 2019, 07:08 PM |
| BMRN | Chief Executive Officer | Apr 30, 2019 | Option Exercise | $68.78 | 309 | 21,254 | 326,520 | May 09, 2019, 08:32 PM |
| BMRN | Chief Executive Officer | May 08, 2019 | Option Exercise | $14.39 | 4,000 | 57,560 | 330,520 | May 09, 2019, 08:32 PM |
| BMRN | Chief Executive Officer | May 08, 2019 | Sale | $82.16 | 4,000 | 328,625 | 326,520 | May 09, 2019, 08:32 PM |
| BMRN | Chief Executive Officer | Apr 26, 2019 | Option Exercise | $14.39 | 3,000 | 43,170 | 329,211 | Apr 30, 2019, 08:09 PM |
| BMRN | Chief Executive Officer | Apr 26, 2019 | Sale | $82.88 | 3,000 | 248,640 | 327,211 | Apr 30, 2019, 08:09 PM |
| BMRN | Chief Executive Officer | Apr 16, 2019 | Option Exercise | $21.51 | 1,000 | 21,510 | 326,211 | Apr 18, 2019, 07:25 PM |
| BMRN | Chief Executive Officer | Apr 12, 2019 | Option Exercise | $14.39 | 4,000 | 57,560 | 329,211 | Apr 15, 2019, 08:26 PM |
| BMRN | Chief Executive Officer | Apr 11, 2019 | Option Exercise | $14.39 | 1,000 | 14,390 | 325,211 | Apr 15, 2019, 08:26 PM |
| BMRN | Chief Executive Officer | Apr 12, 2019 | Sale | $89.12 | 4,000 | 356,480 | 325,211 | Apr 15, 2019, 08:26 PM |
| BMRN | Chief Executive Officer | Apr 08, 2019 | Option Exercise | $14.39 | 3,000 | 43,170 | 327,211 | Apr 09, 2019, 06:23 PM |
| BMRN | Chief Executive Officer | Apr 08, 2019 | Sale | $91.87 | 3,000 | 275,598 | 325,011 | Apr 09, 2019, 06:23 PM |
| BMRN | Chief Executive Officer | Apr 05, 2019 | Option Exercise | $14.39 | 3,000 | 43,170 | 327,211 | Apr 09, 2019, 06:10 PM |
| BMRN | Chief Executive Officer | Apr 05, 2019 | Sale | $93.37 | 3,000 | 280,114 | 324,211 | Apr 09, 2019, 06:10 PM |
| INCY | Director | Mar 29, 2019 | Option Exercise | $86.01 | 168 | 14,450 | 7,064 | Apr 02, 2019, 12:00 AM |
| BMRN | Chief Executive Officer | Mar 27, 2019 | Option Exercise | $14.39 | 1,000 | 14,390 | 324,211 | Mar 29, 2019, 06:07 PM |
| BMRN | Chief Executive Officer | Mar 22, 2019 | Option Exercise | $88.05 | 13,127 | 1,155,832 | 323,211 | Mar 26, 2019, 07:51 PM |
| BMRN | Chief Executive Officer | Mar 25, 2019 | Option Exercise | $14.39 | 4,000 | 57,560 | 327,211 | Mar 26, 2019, 07:51 PM |
| BMRN | Chief Executive Officer | Mar 25, 2019 | Sale | $87.86 | 4,000 | 351,440 | 323,211 | Mar 26, 2019, 07:51 PM |
| BMRN | Chief Executive Officer | Mar 19, 2019 | Option Exercise | $14.39 | 1,000 | 14,390 | 336,338 | Mar 21, 2019, 05:01 PM |
| BMRN | Chief Executive Officer | Mar 15, 2019 | Option Exercise | $94.53 | 28,143 | 2,660,358 | 300,558 | Mar 19, 2019, 07:21 PM |
| BMRN | Chief Executive Officer | Mar 15, 2019 | Option Exercise | $14.39 | 4,000 | 57,560 | 339,338 | Mar 19, 2019, 07:21 PM |
| BMRN | Chief Executive Officer | Mar 15, 2019 | Sale | $94.40 | 4,000 | 377,600 | 335,338 | Mar 19, 2019, 07:21 PM |
| BMRN | Chief Executive Officer | Mar 13, 2019 | Option Exercise | $14.39 | 3,000 | 43,170 | 331,701 | Mar 14, 2019, 02:35 PM |
| BMRN | Chief Executive Officer | Mar 13, 2019 | Sale | $93.42 | 3,000 | 280,253 | 328,701 | Mar 14, 2019, 02:35 PM |
| BMRN | Chief Executive Officer | Mar 12, 2019 | Option Exercise | $14.39 | 4,000 | 57,560 | 332,701 | Mar 13, 2019, 08:00 PM |
| BMRN | Chief Executive Officer | Mar 11, 2019 | Option Exercise | $14.39 | 5,000 | 71,950 | 333,701 | Mar 13, 2019, 08:00 PM |
| BMRN | Chief Executive Officer | Mar 12, 2019 | Sale | $91.44 | 4,000 | 365,770 | 328,701 | Mar 13, 2019, 08:00 PM |
| BMRN | Chief Executive Officer | Mar 11, 2019 | Sale | $88.96 | 5,000 | 444,780 | 328,701 | Mar 13, 2019, 08:00 PM |
| BMRN | Chief Executive Officer | Mar 07, 2019 | Option Exercise | $14.39 | 4,000 | 57,560 | 332,701 | Mar 08, 2019, 08:34 PM |
| BMRN | Chief Executive Officer | Mar 07, 2019 | Sale | $90.78 | 4,000 | 363,120 | 328,701 | Mar 08, 2019, 08:34 PM |
| BMRN | Chief Executive Officer | Mar 01, 2019 | Option Exercise | $94.76 | 4,909 | 465,177 | 328,701 | Mar 05, 2019, 07:16 PM |
| BMRN | Chief Executive Officer | Feb 27, 2019 | Option Exercise | $14.39 | 4,000 | 57,560 | 292,290 | Feb 28, 2019, 08:24 PM |
| BMRN | Chief Executive Officer | Feb 27, 2019 | Sale | $91.78 | 4,000 | 367,120 | 288,290 | Feb 28, 2019, 08:24 PM |
| BMRN | Chief Executive Officer | Feb 21, 2019 | Option Exercise | $14.39 | 3,000 | 43,170 | 291,290 | Feb 22, 2019, 06:24 PM |
| BMRN | Chief Executive Officer | Feb 21, 2019 | Sale | $90.12 | 3,000 | 270,360 | 288,290 | Feb 22, 2019, 06:24 PM |
| BMRN | Chief Executive Officer | Feb 14, 2019 | Option Exercise | $14.39 | 4,000 | 57,560 | 292,290 | Feb 15, 2019, 07:06 PM |
| BMRN | Chief Executive Officer | Feb 14, 2019 | Sale | $95.20 | 4,000 | 380,800 | 288,290 | Feb 15, 2019, 07:06 PM |
| BMRN | Chief Executive Officer | Feb 05, 2019 | Option Exercise | $14.39 | 4,000 | 57,560 | 292,290 | Feb 07, 2019, 07:21 PM |
| BMRN | Chief Executive Officer | Feb 05, 2019 | Sale | $98.63 | 4,000 | 394,520 | 288,290 | Feb 07, 2019, 07:21 PM |
| BMRN | Chief Executive Officer | Jan 22, 2019 | Option Exercise | $14.39 | 3,000 | 43,170 | 291,290 | Jan 24, 2019, 07:07 PM |
| BMRN | Chief Executive Officer | Jan 22, 2019 | Sale | $96.82 | 3,000 | 290,460 | 288,290 | Jan 24, 2019, 07:07 PM |
| BMRN | Chief Executive Officer | Jan 14, 2019 | Option Exercise | $14.39 | 4,000 | 57,560 | 292,290 | Jan 15, 2019, 07:43 PM |
| BMRN | Chief Executive Officer | Jan 14, 2019 | Sale | $93.79 | 4,000 | 375,160 | 288,290 | Jan 15, 2019, 07:43 PM |
| BMRN | Chief Executive Officer | Jan 10, 2019 | Option Exercise | $14.39 | 3,000 | 43,170 | 291,290 | Jan 11, 2019, 03:30 PM |
| BMRN | Chief Executive Officer | Jan 10, 2019 | Sale | $90.55 | 3,000 | 271,650 | 288,290 | Jan 11, 2019, 03:30 PM |
| BMRN | Chief Executive Officer | Jan 08, 2019 | Option Exercise | $14.39 | 6,000 | 86,340 | 294,290 | Jan 10, 2019, 06:50 PM |
| BMRN | Chief Executive Officer | Jan 08, 2019 | Sale | $91.59 | 6,000 | 549,523 | 293,290 | Jan 10, 2019, 06:50 PM |
| BMRN | Chief Executive Officer | Jan 07, 2019 | Option Exercise | $14.39 | 3,000 | 43,170 | 291,290 | Jan 09, 2019, 02:55 PM |
| BMRN | Chief Executive Officer | Jan 07, 2019 | Sale | $87.58 | 3,000 | 262,740 | 288,290 | Jan 09, 2019, 02:55 PM |
| INCY | Director | Dec 31, 2018 | Option Exercise | $63.59 | 228 | 14,499 | 6,896 | Jan 03, 2019, 04:02 PM |
| BMRN | Chief Executive Officer | Dec 28, 2018 | Option Exercise | $14.39 | 3,000 | 43,170 | 291,290 | Jan 02, 2019, 05:24 PM |
| BMRN | Chief Executive Officer | Dec 28, 2018 | Sale | $84.04 | 3,000 | 252,120 | 288,290 | Jan 02, 2019, 05:24 PM |
| BMRN | Chief Executive Officer | Dec 26, 2018 | Option Exercise | $14.39 | 4,000 | 57,560 | 292,290 | Dec 27, 2018, 05:35 PM |
| BMRN | Chief Executive Officer | Dec 26, 2018 | Sale | $80.50 | 4,000 | 322,000 | 288,290 | Dec 27, 2018, 05:35 PM |
| BMRN | Chief Executive Officer | Dec 14, 2018 | Option Exercise | $17.86 | 2,000 | 35,720 | 290,290 | Dec 18, 2018, 07:58 PM |
| BMRN | Chief Executive Officer | Dec 14, 2018 | Sale | $92.64 | 2,000 | 185,280 | 288,290 | Dec 18, 2018, 07:58 PM |
| BMRN | Chief Executive Officer | Dec 12, 2018 | Option Exercise | $17.86 | 2,000 | 35,720 | 290,290 | Dec 14, 2018, 02:44 PM |
| BMRN | Chief Executive Officer | Dec 12, 2018 | Sale | $93.12 | 2,000 | 186,240 | 288,290 | Dec 14, 2018, 02:44 PM |
| INCY | Director | Nov 08, 2018 | Buy | $68.77 | 1,000 | 68,765 | 6,668 | Nov 09, 2018, 04:21 PM |
| BMRN | Chief Executive Officer | Nov 02, 2018 | Option Exercise | $17.86 | 1,500 | 26,790 | 289,790 | Nov 05, 2018, 05:34 PM |
| BMRN | Chief Executive Officer | Nov 02, 2018 | Sale | $97.88 | 1,500 | 146,820 | 288,290 | Nov 05, 2018, 05:34 PM |
| BMRN | Chief Executive Officer | Nov 01, 2018 | Option Exercise | $14.39 | 4,000 | 57,560 | 292,290 | Nov 02, 2018, 05:34 PM |
| BMRN | Chief Executive Officer | Nov 01, 2018 | Sale | $92.55 | 4,000 | 370,200 | 288,290 | Nov 02, 2018, 05:34 PM |
| BMRN | Chief Executive Officer | Oct 30, 2018 | Option Exercise | $14.39 | 1,000 | 14,390 | 288,290 | Nov 01, 2018, 07:26 PM |
| BMRN | Chief Executive Officer | Oct 24, 2018 | Option Exercise | $14.39 | 1,000 | 14,390 | 287,290 | Oct 26, 2018, 06:08 PM |
| BMRN | Chief Executive Officer | Oct 03, 2018 | Option Exercise | $17.86 | 1,500 | 26,790 | 287,790 | Oct 05, 2018, 05:42 PM |
| BMRN | Chief Executive Officer | Oct 03, 2018 | Sale | $99.36 | 1,500 | 149,040 | 286,290 | Oct 05, 2018, 05:42 PM |
| INCY | Director | Sep 28, 2018 | Option Exercise | $69.08 | 209 | 14,438 | 5,668 | Oct 02, 2018, 04:11 PM |
| BMRN | Chief Executive Officer | Sep 25, 2018 | Option Exercise | $14.39 | 1,000 | 14,390 | 286,290 | Sep 27, 2018, 01:58 PM |
| VTL | Director | Sep 24, 2018 | Sale | $0.30 | 26,619 | 8,002 | 18,500 | Sep 24, 2018, 07:24 PM |
| VTL | Director | Sep 13, 2018 | Sale | $0.47 | 20,000 | 9,400 | 45,119 | Sep 17, 2018, 09:24 PM |
| BMRN | Chief Executive Officer | Sep 04, 2018 | Option Exercise | $17.86 | 1,500 | 26,790 | 286,790 | Sep 06, 2018, 05:41 PM |
| BMRN | Chief Executive Officer | Sep 04, 2018 | Sale | $98.16 | 1,500 | 147,240 | 285,290 | Sep 06, 2018, 05:41 PM |
| BMRN | Chief Executive Officer | Jul 23, 2018 | Option Exercise | $17.86 | 1,500 | 26,790 | 286,790 | Jul 25, 2018, 07:47 PM |
| BMRN | Chief Executive Officer | Jul 23, 2018 | Sale | $101.69 | 1,500 | 152,535 | 285,290 | Jul 25, 2018, 07:47 PM |
| INCY | Director | Jun 29, 2018 | Option Exercise | $67.00 | 216 | 14,472 | 5,459 | Jul 03, 2018, 04:08 PM |
| BMRN | Chief Executive Officer | Jun 13, 2018 | Option Exercise | $14.39 | 1,000 | 14,390 | 285,290 | Jun 14, 2018, 07:53 PM |
| BMRN | Chief Executive Officer | Jun 04, 2018 | Option Exercise | $92.07 | 6,310 | 580,962 | 284,290 | Jun 06, 2018, 07:49 PM |
| BMRN | Chief Executive Officer | May 17, 2018 | Option Exercise | $38.59 | 18,750 | 723,563 | 309,350 | May 18, 2018, 06:15 PM |
| BMRN | Chief Executive Officer | May 17, 2018 | Sale | $88.66 | 18,750 | 1,662,356 | 290,600 | May 18, 2018, 06:15 PM |
| BMRN | Chief Executive Officer | May 16, 2018 | Option Exercise | $38.59 | 18,750 | 723,563 | 309,350 | May 17, 2018, 08:03 PM |
| BMRN | Chief Executive Officer | May 16, 2018 | Sale | $89.13 | 18,750 | 1,671,131 | 290,600 | May 17, 2018, 08:03 PM |
| BMRN | Chief Executive Officer | May 15, 2018 | Option Exercise | $38.59 | 18,750 | 723,563 | 309,350 | May 16, 2018, 06:30 PM |
| BMRN | Chief Executive Officer | May 14, 2018 | Option Exercise | $38.59 | 18,750 | 723,563 | 309,350 | May 16, 2018, 06:30 PM |
| BMRN | Chief Executive Officer | May 15, 2018 | Sale | $88.29 | 18,750 | 1,655,434 | 290,600 | May 16, 2018, 06:30 PM |
| BMRN | Chief Executive Officer | May 14, 2018 | Sale | $89.22 | 18,750 | 1,672,851 | 290,600 | May 16, 2018, 06:30 PM |
| BMRN | Chief Executive Officer | Apr 30, 2018 | Option Exercise | $68.78 | 309 | 21,254 | 290,600 | May 14, 2018, 09:28 PM |
| BMRN | Chief Executive Officer | May 11, 2018 | Option Exercise | $38.59 | 18,750 | 723,563 | 309,350 | May 14, 2018, 09:28 PM |
| BMRN | Chief Executive Officer | May 10, 2018 | Option Exercise | $38.59 | 18,750 | 723,563 | 309,350 | May 14, 2018, 09:28 PM |
| BMRN | Chief Executive Officer | May 11, 2018 | Sale | $88.42 | 18,750 | 1,657,856 | 290,600 | May 14, 2018, 09:28 PM |
| BMRN | Chief Executive Officer | May 10, 2018 | Sale | $89.59 | 18,750 | 1,679,794 | 290,600 | May 14, 2018, 09:28 PM |
| BMRN | Chief Executive Officer | Mar 22, 2018 | Option Exercise | $81.36 | 13,127 | 1,068,013 | 283,979 | Apr 27, 2018, 06:31 PM |
| BMRN | Chief Executive Officer | Apr 24, 2018 | Option Exercise | $38.59 | 10,000 | 385,900 | 300,031 | Apr 25, 2018, 08:30 PM |
| BMRN | Chief Executive Officer | Apr 23, 2018 | Option Exercise | $38.59 | 10,000 | 385,900 | 300,031 | Apr 25, 2018, 08:30 PM |
| BMRN | Chief Executive Officer | Apr 23, 2018 | Sale | $82.58 | 10,000 | 825,811 | 290,031 | Apr 25, 2018, 08:30 PM |
| BMRN | Chief Executive Officer | Apr 24, 2018 | Sale | $82.29 | 10,000 | 822,887 | 290,031 | Apr 25, 2018, 08:30 PM |
| BMRN | Chief Executive Officer | Apr 20, 2018 | Option Exercise | $38.59 | 10,000 | 385,900 | 300,031 | Apr 24, 2018, 07:50 PM |
| BMRN | Chief Executive Officer | Apr 20, 2018 | Sale | $83.65 | 10,000 | 836,458 | 290,031 | Apr 24, 2018, 07:50 PM |
| BMRN | Chief Executive Officer | Apr 05, 2018 | Option Exercise | $14.39 | 1,000 | 14,390 | 290,031 | Apr 09, 2018, 03:51 PM |
| BMRN | Chief Executive Officer | Apr 02, 2018 | Option Exercise | $14.39 | 1,000 | 14,390 | 289,031 | Apr 03, 2018, 08:56 PM |
| INCY | Director | Mar 29, 2018 | Option Exercise | $83.33 | 174 | 14,499 | 5,243 | Apr 03, 2018, 12:00 AM |
| BMRN | Chief Executive Officer | Mar 28, 2018 | Option Exercise | $16.13 | 2,000 | 32,250 | 288,031 | Mar 30, 2018, 07:58 PM |
| BMRN | Chief Executive Officer | Mar 27, 2018 | Option Exercise | $14.39 | 1,000 | 14,390 | 286,031 | Mar 28, 2018, 06:36 PM |
| BMRN | Chief Executive Officer | Mar 26, 2018 | Option Exercise | $14.39 | 1,000 | 14,390 | 285,031 | Mar 28, 2018, 06:36 PM |
| BMRN | Chief Executive Officer | Mar 22, 2018 | Option Exercise | $81.36 | 13,075 | 1,063,782 | 284,031 | Mar 26, 2018, 07:27 PM |
| BMRN | Chief Executive Officer | Mar 22, 2018 | Option Exercise | $14.39 | 1,000 | 14,390 | 297,106 | Mar 26, 2018, 07:27 PM |
| BMRN | Chief Executive Officer | Mar 16, 2018 | Option Exercise | $38.59 | 15,000 | 578,850 | 311,106 | Mar 20, 2018, 07:46 PM |
| BMRN | Chief Executive Officer | Mar 16, 2018 | Sale | $83.26 | 15,000 | 1,248,853 | 296,106 | Mar 20, 2018, 07:46 PM |
| BMRN | Chief Executive Officer | Mar 15, 2018 | Option Exercise | $83.57 | 14,908 | 1,245,862 | 249,766 | Mar 20, 2018, 02:16 PM |
| BMRN | Chief Executive Officer | Mar 15, 2018 | Option Exercise | $38.59 | 15,000 | 578,850 | 279,674 | Mar 20, 2018, 02:16 PM |
| BMRN | Chief Executive Officer | Mar 15, 2018 | Sale | $84.73 | 15,000 | 1,270,900 | 264,674 | Mar 20, 2018, 02:16 PM |
| BMRN | Chief Executive Officer | Mar 02, 2018 | Option Exercise | $79.86 | 8,542 | 682,164 | 264,674 | Mar 06, 2018, 08:55 PM |
| BMRN | Chief Executive Officer | Mar 02, 2018 | Option Exercise | $14.39 | 1,000 | 14,390 | 273,216 | Mar 06, 2018, 08:55 PM |
| BMRN | Chief Executive Officer | Feb 15, 2018 | Option Exercise | $38.59 | 10,000 | 385,900 | 236,494 | Feb 20, 2018, 08:40 PM |
| BMRN | Chief Executive Officer | Feb 15, 2018 | Sale | $84.63 | 10,000 | 846,285 | 226,494 | Feb 20, 2018, 08:40 PM |
| BMRN | Chief Executive Officer | Jan 05, 2018 | Option Exercise | $38.59 | 10,000 | 385,900 | 235,894 | Jan 09, 2018, 08:36 PM |
| BMRN | Chief Executive Officer | Jan 05, 2018 | Sale | $90.32 | 10,000 | 903,203 | 225,894 | Jan 09, 2018, 08:36 PM |
| INCY | Director | Dec 29, 2017 | Option Exercise | $94.71 | 153 | 14,491 | 5,069 | Jan 03, 2018, 12:00 AM |
| BMRN | Chief Executive Officer | Dec 29, 2017 | Option Exercise | $38.59 | 10,000 | 385,900 | 235,894 | Jan 02, 2018, 05:29 PM |
| BMRN | Chief Executive Officer | Dec 28, 2017 | Option Exercise | $38.59 | 10,000 | 385,900 | 235,894 | Jan 02, 2018, 05:29 PM |
| BMRN | Chief Executive Officer | Dec 29, 2017 | Sale | $89.61 | 10,000 | 896,125 | 225,894 | Jan 02, 2018, 05:29 PM |
| BMRN | Chief Executive Officer | Dec 28, 2017 | Sale | $89.89 | 10,000 | 898,912 | 225,894 | Jan 02, 2018, 05:29 PM |
| INCY | Director | Sep 29, 2017 | Option Exercise | $116.74 | 124 | 14,476 | 4,916 | Oct 03, 2017, 04:13 PM |
| VTL | Director | Sep 13, 2017 | Buy | $4.00 | 10,000 | 39,969 | 65,119 | Sep 14, 2017, 04:15 PM |
| INCY | Director | Jun 30, 2017 | Option Exercise | $125.91 | 115 | 14,480 | 4,792 | Jul 05, 2017, 04:17 PM |
| VTL | Director | Jun 13, 2017 | Buy | $3.00 | 16,000 | 48,069 | 55,119 | Jun 15, 2017, 04:27 PM |
| BMRN | Chief Executive Officer | Jun 02, 2017 | Option Exercise | $90.72 | 6,640 | 602,381 | 226,924 | Jun 06, 2017, 08:34 PM |
| BMRN | Chief Executive Officer | Jun 05, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 231,924 | Jun 06, 2017, 08:34 PM |
| BMRN | Chief Executive Officer | Jun 02, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 238,564 | Jun 06, 2017, 08:34 PM |
| BMRN | Chief Executive Officer | Jun 05, 2017 | Sale | $90.56 | 5,000 | 452,800 | 226,924 | Jun 06, 2017, 08:34 PM |
| BMRN | Chief Executive Officer | Jun 02, 2017 | Sale | $89.70 | 5,000 | 448,500 | 233,564 | Jun 06, 2017, 08:34 PM |
| BMRN | Chief Executive Officer | Jun 01, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 238,564 | Jun 05, 2017, 07:05 PM |
| BMRN | Chief Executive Officer | Jun 01, 2017 | Sale | $87.53 | 5,000 | 437,650 | 233,564 | Jun 05, 2017, 07:05 PM |
| BMRN | Chief Executive Officer | May 31, 2017 | Option Exercise | $17.33 | 7,423 | 128,641 | 240,987 | Jun 02, 2017, 05:52 PM |
| BMRN | Chief Executive Officer | May 31, 2017 | Sale | $88.29 | 7,423 | 655,377 | 233,564 | Jun 02, 2017, 05:52 PM |
| INCY | Director | May 31, 2017 | Buy | $131.80 | 500 | 65,900 | 4,677 | Jun 02, 2017, 04:14 PM |
| BMRN | Chief Executive Officer | May 24, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 238,564 | May 26, 2017, 05:02 PM |
| BMRN | Chief Executive Officer | May 24, 2017 | Sale | $88.38 | 5,000 | 441,900 | 233,564 | May 26, 2017, 05:02 PM |
| BMRN | Chief Executive Officer | May 17, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 238,564 | May 19, 2017, 10:33 AM |
| BMRN | Chief Executive Officer | May 17, 2017 | Sale | $91.73 | 5,000 | 458,650 | 233,564 | May 19, 2017, 10:33 AM |
| BMRN | Chief Executive Officer | May 15, 2017 | Option Exercise | $91.50 | 4,932 | 451,278 | 233,564 | May 17, 2017, 06:51 PM |
| INCY | Director | May 15, 2017 | Buy | $115.00 | 500 | 57,500 | 4,177 | May 17, 2017, 04:18 PM |
| BMRN | Chief Executive Officer | May 12, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 243,496 | May 16, 2017, 06:47 PM |
| BMRN | Chief Executive Officer | May 12, 2017 | Sale | $89.23 | 5,000 | 446,150 | 238,496 | May 16, 2017, 06:47 PM |
| BMRN | Chief Executive Officer | Apr 28, 2017 | Option Exercise | $70.30 | 302 | 21,232 | 238,496 | May 09, 2017, 01:19 PM |
| BMRN | Chief Executive Officer | May 08, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 243,496 | May 09, 2017, 01:19 PM |
| BMRN | Chief Executive Officer | May 05, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 243,496 | May 09, 2017, 01:19 PM |
| BMRN | Chief Executive Officer | May 05, 2017 | Sale | $99.00 | 5,000 | 495,000 | 238,496 | May 09, 2017, 01:19 PM |
| BMRN | Chief Executive Officer | May 08, 2017 | Sale | $93.17 | 5,000 | 465,850 | 238,496 | May 09, 2017, 01:19 PM |
| INCY | Director | Apr 28, 2017 | Buy | $124.26 | 500 | 62,130 | 3,677 | May 02, 2017, 04:31 PM |
| BMRN | Chief Executive Officer | Apr 27, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 243,194 | May 01, 2017, 05:39 PM |
| BMRN | Chief Executive Officer | Apr 27, 2017 | Sale | $95.72 | 5,000 | 478,600 | 238,194 | May 01, 2017, 05:39 PM |
| BMRN | Chief Executive Officer | Apr 25, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 243,194 | Apr 27, 2017, 06:49 PM |
| BMRN | Chief Executive Officer | Apr 25, 2017 | Sale | $94.00 | 5,000 | 470,000 | 238,194 | Apr 27, 2017, 06:49 PM |
| INCY | Director | Apr 13, 2017 | Buy | $139.66 | 1,000 | 139,660 | 3,177 | Apr 17, 2017, 04:56 PM |
| INCY | Director | Apr 07, 2017 | Buy | $139.48 | 1,000 | 139,480 | 2,177 | Apr 11, 2017, 04:06 PM |
| BMRN | Chief Executive Officer | Apr 04, 2017 | Option Exercise | $14.39 | 3,000 | 43,170 | 238,194 | Apr 06, 2017, 05:28 PM |
| INCY | Director | Mar 31, 2017 | Option Exercise | $133.67 | 108 | 14,436 | 1,177 | Mar 31, 2017, 05:06 PM |
| BMRN | Chief Executive Officer | Mar 15, 2017 | Option Exercise | $92.50 | 15,690 | 1,451,325 | 190,674 | Mar 17, 2017, 06:27 PM |
| BMRN | Chief Executive Officer | Mar 16, 2017 | Option Exercise | $71.33 | 5,000 | 356,650 | 195,674 | Mar 17, 2017, 06:27 PM |
| BMRN | Chief Executive Officer | Mar 15, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 211,364 | Mar 17, 2017, 06:27 PM |
| BMRN | Chief Executive Officer | Mar 16, 2017 | Sale | $91.96 | 5,000 | 459,800 | 190,674 | Mar 17, 2017, 06:27 PM |
| BMRN | Chief Executive Officer | Mar 15, 2017 | Sale | $91.42 | 5,000 | 457,100 | 206,364 | Mar 17, 2017, 06:27 PM |
| BMRN | Chief Executive Officer | Mar 13, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 211,364 | Mar 15, 2017, 07:16 PM |
| BMRN | Chief Executive Officer | Mar 13, 2017 | Sale | $92.68 | 5,000 | 463,400 | 206,364 | Mar 15, 2017, 07:16 PM |
| BMRN | Chief Executive Officer | Mar 10, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 211,364 | Mar 13, 2017, 07:59 PM |
| BMRN | Chief Executive Officer | Mar 09, 2017 | Option Exercise | $17.33 | 6,000 | 103,980 | 212,364 | Mar 13, 2017, 07:59 PM |
| BMRN | Chief Executive Officer | Mar 10, 2017 | Sale | $91.09 | 5,000 | 455,450 | 206,364 | Mar 13, 2017, 07:59 PM |
| BMRN | Chief Executive Officer | Mar 09, 2017 | Sale | $90.18 | 6,000 | 541,080 | 206,364 | Mar 13, 2017, 07:59 PM |
| BMRN | Chief Executive Officer | Mar 03, 2017 | Option Exercise | $93.95 | 8,989 | 844,517 | 206,364 | Mar 07, 2017, 06:37 PM |
| BMRN | Chief Executive Officer | Jan 26, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 175,682 | Jan 27, 2017, 05:46 PM |
| BMRN | Chief Executive Officer | Jan 25, 2017 | Option Exercise | $17.33 | 5,000 | 86,650 | 175,682 | Jan 27, 2017, 05:46 PM |
| BMRN | Chief Executive Officer | Jan 26, 2017 | Sale | $84.00 | 5,000 | 420,000 | 170,682 | Jan 27, 2017, 05:46 PM |
| BMRN | Chief Executive Officer | Jan 25, 2017 | Sale | $84.44 | 5,000 | 422,200 | 170,682 | Jan 27, 2017, 05:46 PM |
| BMRN | Chief Executive Officer | Jan 10, 2017 | Option Exercise | $17.33 | 4,000 | 69,320 | 174,682 | Jan 12, 2017, 06:48 PM |
| BMRN | Chief Executive Officer | Jan 11, 2017 | Option Exercise | $17.33 | 4,000 | 69,320 | 174,682 | Jan 12, 2017, 06:48 PM |
| BMRN | Chief Executive Officer | Jan 11, 2017 | Sale | $89.84 | 4,000 | 359,360 | 170,682 | Jan 12, 2017, 06:48 PM |
| BMRN | Chief Executive Officer | Jan 10, 2017 | Sale | $91.31 | 4,000 | 365,240 | 170,682 | Jan 12, 2017, 06:48 PM |
| BMRN | Chief Executive Officer | Jan 09, 2017 | Option Exercise | $17.33 | 4,000 | 69,320 | 174,682 | Jan 10, 2017, 04:53 PM |
| BMRN | Chief Executive Officer | Jan 06, 2017 | Option Exercise | $17.33 | 4,000 | 69,320 | 174,682 | Jan 10, 2017, 04:53 PM |
| BMRN | Chief Executive Officer | Jan 09, 2017 | Sale | $89.79 | 4,000 | 359,160 | 170,682 | Jan 10, 2017, 04:53 PM |
| BMRN | Chief Executive Officer | Jan 06, 2017 | Sale | $87.19 | 4,000 | 348,760 | 170,682 | Jan 10, 2017, 04:53 PM |
| BMRN | Chief Executive Officer | Dec 30, 2016 | Option Exercise | $17.33 | 4,000 | 69,320 | 174,682 | Jan 03, 2017, 05:46 PM |
| BMRN | Chief Executive Officer | Dec 29, 2016 | Option Exercise | $17.33 | 4,000 | 69,320 | 174,682 | Jan 03, 2017, 05:46 PM |
| BMRN | Chief Executive Officer | Dec 29, 2016 | Sale | $83.84 | 4,000 | 335,360 | 170,682 | Jan 03, 2017, 05:46 PM |
| BMRN | Chief Executive Officer | Dec 30, 2016 | Sale | $83.35 | 4,000 | 333,400 | 170,682 | Jan 03, 2017, 05:46 PM |
| INCY | Director | Dec 30, 2016 | Option Exercise | $100.27 | 144 | 14,439 | 1,069 | Dec 30, 2016, 05:07 PM |
| BMRN | Chief Executive Officer | Nov 21, 2016 | Option Exercise | $26.49 | 69,744 | 1,847,519 | 240,426 | Nov 23, 2016, 04:42 PM |
| BMRN | Chief Executive Officer | Nov 22, 2016 | Option Exercise | $26.49 | 69,743 | 1,847,492 | 240,425 | Nov 23, 2016, 04:42 PM |
| BMRN | Chief Executive Officer | Nov 22, 2016 | Sale | $85.69 | 69,743 | 5,976,515 | 170,682 | Nov 23, 2016, 04:42 PM |
| BMRN | Chief Executive Officer | Nov 21, 2016 | Sale | $87.56 | 69,744 | 6,106,478 | 170,682 | Nov 23, 2016, 04:42 PM |
| BMRN | Chief Executive Officer | Nov 16, 2016 | Option Exercise | $17.54 | 41,670 | 730,892 | 365,038 | Nov 18, 2016, 05:37 PM |
| BMRN | Chief Executive Officer | Nov 16, 2016 | Sale | $90.97 | 41,670 | 3,790,795 | 323,368 | Nov 18, 2016, 05:37 PM |
| BMRN | Chief Executive Officer | Nov 08, 2016 | Option Exercise | $21.51 | 70,000 | 1,505,700 | 393,368 | Nov 09, 2016, 08:23 PM |
| BMRN | Chief Executive Officer | Nov 07, 2016 | Option Exercise | $21.51 | 70,000 | 1,505,700 | 393,368 | Nov 09, 2016, 08:23 PM |
| BMRN | Chief Executive Officer | Nov 08, 2016 | Sale | $82.83 | 70,000 | 5,797,806 | 323,368 | Nov 09, 2016, 08:23 PM |
| BMRN | Chief Executive Officer | Nov 07, 2016 | Sale | $82.52 | 70,000 | 5,776,435 | 323,368 | Nov 09, 2016, 08:23 PM |
| BMRN | Chief Executive Officer | Oct 28, 2016 | Option Exercise | $14.39 | 60,000 | 863,400 | 383,368 | Oct 31, 2016, 07:33 PM |
| BMRN | Chief Executive Officer | Oct 27, 2016 | Option Exercise | $14.39 | 60,000 | 863,400 | 383,368 | Oct 31, 2016, 07:33 PM |
| BMRN | Chief Executive Officer | Oct 28, 2016 | Sale | $81.27 | 60,000 | 4,875,990 | 323,368 | Oct 31, 2016, 07:33 PM |
| BMRN | Chief Executive Officer | Oct 27, 2016 | Sale | $81.34 | 60,000 | 4,880,448 | 323,368 | Oct 31, 2016, 07:33 PM |
| BMRN | Chief Executive Officer | Oct 17, 2016 | Option Exercise | $17.54 | 41,666 | 730,822 | 365,034 | Oct 19, 2016, 04:41 PM |
| BMRN | Chief Executive Officer | Oct 17, 2016 | Sale | $84.39 | 41,666 | 3,516,227 | 323,368 | Oct 19, 2016, 04:41 PM |
| BMRN | Chief Executive Officer | Oct 14, 2016 | Option Exercise | $17.86 | 11,000 | 196,460 | 334,368 | Oct 17, 2016, 07:16 PM |
| BMRN | Chief Executive Officer | Oct 13, 2016 | Option Exercise | $38.59 | 53,125 | 2,050,094 | 376,493 | Oct 17, 2016, 07:16 PM |
| BMRN | Chief Executive Officer | Oct 14, 2016 | Sale | $86.89 | 11,000 | 955,814 | 323,368 | Oct 17, 2016, 07:16 PM |
| BMRN | Chief Executive Officer | Oct 13, 2016 | Sale | $86.98 | 53,125 | 4,620,563 | 323,368 | Oct 17, 2016, 07:16 PM |
| INCY | Director | Sep 30, 2016 | Option Exercise | $94.29 | 153 | 14,426 | 925 | Oct 04, 2016, 04:39 PM |
| BMRN | Chief Executive Officer | Sep 30, 2016 | Option Exercise | $38.59 | 53,125 | 2,050,094 | 431,709 | Oct 04, 2016, 03:59 PM |
| BMRN | Chief Executive Officer | Sep 30, 2016 | Sale | $92.02 | 53,125 | 4,888,780 | 378,584 | Oct 04, 2016, 03:59 PM |
| BMRN | Chief Executive Officer | Sep 29, 2016 | Option Exercise | $38.59 | 53,125 | 2,050,094 | 431,709 | Oct 03, 2016, 06:37 PM |
| BMRN | Chief Executive Officer | Sep 29, 2016 | Sale | $93.65 | 53,125 | 4,974,901 | 378,584 | Oct 03, 2016, 06:37 PM |
| BMRN | Chief Executive Officer | Sep 16, 2016 | Option Exercise | $29.34 | 94,791 | 2,780,915 | 431,709 | Sep 19, 2016, 06:41 PM |
| BMRN | Chief Executive Officer | Sep 15, 2016 | Option Exercise | $17.33 | 42,577 | 737,859 | 421,161 | Sep 19, 2016, 06:41 PM |
| BMRN | Chief Executive Officer | Sep 16, 2016 | Sale | $95.56 | 94,791 | 9,058,601 | 378,584 | Sep 19, 2016, 06:41 PM |
| BMRN | Chief Executive Officer | Sep 15, 2016 | Sale | $94.85 | 42,577 | 4,038,360 | 378,584 | Sep 19, 2016, 06:41 PM |
| BMRN | Chief Executive Officer | Aug 16, 2016 | Option Exercise | $17.54 | 41,666 | 730,822 | 420,250 | Aug 17, 2016, 04:37 PM |
| BMRN | Chief Executive Officer | Aug 16, 2016 | Sale | $91.49 | 41,666 | 3,811,868 | 378,584 | Aug 17, 2016, 04:37 PM |
| BMRN | Chief Executive Officer | Jul 18, 2016 | Option Exercise | $17.54 | 41,666 | 730,822 | 420,250 | Jul 20, 2016, 07:51 PM |
| BMRN | Chief Executive Officer | Jul 18, 2016 | Sale | $92.72 | 41,666 | 3,863,272 | 378,584 | Jul 20, 2016, 07:51 PM |
| INCY | Director | Jun 30, 2016 | Option Exercise | $79.98 | 181 | 14,476 | 772 | Jul 05, 2016, 04:31 PM |
| BMRN | Chief Executive Officer | Jun 16, 2016 | Option Exercise | $17.54 | 41,666 | 730,822 | 420,250 | Jun 20, 2016, 08:23 PM |
| BMRN | Chief Executive Officer | Jun 16, 2016 | Sale | $80.55 | 41,666 | 3,356,196 | 378,584 | Jun 20, 2016, 08:23 PM |
| BMRN | Chief Executive Officer | Jun 03, 2016 | Option Exercise | $90.00 | 6,640 | 597,600 | 378,584 | Jun 07, 2016, 11:06 AM |
| BMRN | Chief Executive Officer | May 13, 2016 | Option Exercise | $82.71 | 4,932 | 407,926 | 385,224 | May 17, 2016, 03:11 PM |
| BMRN | Chief Executive Officer | May 06, 2016 | Option Exercise | $80.80 | 5,479 | 442,703 | 390,156 | May 09, 2016, 08:47 PM |
| BMRN | Chief Executive Officer | May 05, 2016 | Option Exercise | $12.99 | 10,000 | 129,900 | 10,000 | May 09, 2016, 08:47 PM |
| BMRN | Chief Executive Officer | May 05, 2016 | Option Exercise | $46.57 | 20,000 | 931,389 | 10,000 | May 09, 2016, 08:47 PM |
| BMRN | Chief Executive Officer | May 05, 2016 | Option Exercise | $12.99 | 10,000 | 129,900 | 10,000 | May 09, 2016, 08:47 PM |
| BMRN | Chief Executive Officer | May 05, 2016 | Option Exercise | $12.99 | 20,000 | 259,800 | 20,000 | May 09, 2016, 08:47 PM |
| BMRN | Chief Executive Officer | May 05, 2016 | Option Exercise | $12.99 | 10,000 | 129,900 | 10,000 | May 09, 2016, 08:47 PM |
| BMRN | Chief Executive Officer | May 05, 2016 | Sale | $80.15 | 10,000 | 801,489 | 0 | May 09, 2016, 08:47 PM |
| BMRN | Chief Executive Officer | May 05, 2016 | Sale | $80.15 | 20,000 | 1,602,978 | 0 | May 09, 2016, 08:47 PM |
| BMRN | Chief Executive Officer | May 05, 2016 | Sale | $80.15 | 10,000 | 801,489 | 0 | May 09, 2016, 08:47 PM |
| BMRN | Chief Executive Officer | May 05, 2016 | Sale | $80.15 | 10,000 | 801,489 | 0 | May 09, 2016, 08:47 PM |
| BMRN | Chief Executive Officer | Apr 29, 2016 | Option Exercise | $51.26 | 414 | 21,223 | 395,635 | May 04, 2016, 10:11 AM |
| BMRN | Chief Executive Officer | May 02, 2016 | Option Exercise | $12.99 | 36,500 | 474,135 | 432,135 | May 04, 2016, 10:11 AM |
| BMRN | Chief Executive Officer | May 02, 2016 | Sale | $85.01 | 36,500 | 3,102,931 | 395,635 | May 04, 2016, 10:11 AM |
| BMRN | Chief Executive Officer | Apr 06, 2016 | Option Exercise | $14.39 | 1,500 | 21,585 | 395,221 | Apr 07, 2016, 08:49 PM |
| BMRN | Chief Executive Officer | Apr 05, 2016 | Option Exercise | $14.39 | 1,500 | 21,585 | 393,721 | Apr 07, 2016, 08:49 PM |
| INCY | Director | Mar 31, 2016 | Option Exercise | $72.47 | 200 | 14,494 | 591 | Apr 01, 2016, 04:10 PM |
| BMRN | Chief Executive Officer | Mar 03, 2016 | Option Exercise | $89.57 | 8,989 | 805,145 | 331,511 | Mar 07, 2016, 08:47 PM |
| BMRN | Chief Executive Officer | Feb 29, 2016 | Option Exercise | $81.87 | 192,982 | 15,799,437 | 350,500 | Mar 02, 2016, 08:38 PM |
| BMRN | Chief Executive Officer | Mar 01, 2016 | Sale | $84.28 | 10,000 | 842,769 | 345,479 | Mar 02, 2016, 08:38 PM |
| INCY | Director | Dec 31, 2015 | Option Exercise | $108.45 | 133 | 14,424 | 391 | Dec 31, 2015, 04:28 PM |
| BMRN | Chief Executive Officer | Nov 30, 2015 | Sale | $94.74 | 1,000 | 94,744 | 25,758 | Dec 02, 2015, 06:58 PM |
| BMRN | Chief Executive Officer | Oct 15, 2015 | Sale | $108.24 | 1,000 | 108,241 | 26,758 | Oct 19, 2015, 01:39 PM |
| INCY | Director | Oct 01, 2015 | Option Exercise | $110.33 | 131 | 14,453 | 258 | Oct 02, 2015, 04:29 PM |
| BMRN | Chief Executive Officer | Sep 14, 2015 | Sale | $131.43 | 1,000 | 131,432 | 27,758 | Sep 16, 2015, 08:09 PM |
| VTL | Director | Sep 10, 2015 | Buy | $3.05 | 6,000 | 18,293 | 39,119 | Sep 11, 2015, 12:47 PM |
| VTL | Director | Sep 09, 2015 | Buy | $3.10 | 8,000 | 24,800 | 33,119 | Sep 11, 2015, 12:47 PM |
| BMRN | Chief Executive Officer | Aug 12, 2015 | Sale | $134.72 | 1,500 | 202,083 | 28,758 | Aug 13, 2015, 10:40 AM |
| BMRN | Chief Executive Officer | Jul 07, 2015 | Sale | $139.07 | 1,500 | 208,599 | 30,258 | Jul 09, 2015, 05:06 PM |
| INCY | Director | Jul 01, 2015 | Option Exercise | $104.21 | 127 | 13,235 | 127 | Jul 06, 2015, 04:28 PM |
| BMRN | Chief Executive Officer | Jun 04, 2015 | Option Exercise | $120.46 | 6,640 | 799,854 | 229,254 | Jun 08, 2015, 06:01 PM |
| BMRN | Chief Executive Officer | May 21, 2015 | Sale | $126.11 | 1,500 | 189,158 | 31,758 | May 26, 2015, 07:54 PM |
| BMRN | Chief Executive Officer | May 15, 2015 | Option Exercise | $122.78 | 4,932 | 605,551 | 235,894 | May 19, 2015, 07:17 PM |
| BMRN | Chief Executive Officer | May 12, 2015 | Option Exercise | $121.09 | 2,349 | 284,440 | 240,826 | May 14, 2015, 06:52 PM |
| BMRN | Chief Executive Officer | May 08, 2015 | Option Exercise | $121.66 | 5,479 | 666,575 | 243,175 | May 12, 2015, 07:19 PM |
| BMRN | Chief Executive Officer | Apr 30, 2015 | Option Exercise | $51.26 | 908 | 46,547 | 252,159 | May 05, 2015, 07:02 PM |
| BMRN | Chief Executive Officer | May 01, 2015 | Option Exercise | $6.46 | 23,218 | 149,988 | 56,476 | May 05, 2015, 07:02 PM |
| BMRN | Chief Executive Officer | May 01, 2015 | Sale | $114.98 | 3,505 | 402,991 | 248,654 | May 05, 2015, 07:02 PM |
| BMRN | Chief Executive Officer | May 01, 2015 | Sale | $114.98 | 23,218 | 2,669,513 | 33,258 | May 05, 2015, 07:02 PM |
| BMRN | Chief Executive Officer | Apr 01, 2015 | Option Exercise | $6.46 | 22,546 | 145,647 | 55,804 | Apr 03, 2015, 01:05 PM |
| BMRN | Chief Executive Officer | Apr 01, 2015 | Sale | $120.53 | 22,546 | 2,717,537 | 33,258 | Apr 03, 2015, 01:05 PM |
| BMRN | Chief Executive Officer | Apr 01, 2015 | Sale | $120.53 | 3,506 | 422,589 | 251,251 | Apr 03, 2015, 01:05 PM |
| BMRN | Chief Executive Officer | Mar 20, 2015 | Sale | $126.40 | 1,000 | 126,396 | 33,258 | Mar 24, 2015, 07:05 PM |
| BMRN | Chief Executive Officer | Mar 17, 2015 | Sale | $124.87 | 1,000 | 124,866 | 34,258 | Mar 18, 2015, 08:02 PM |
| BMRN | Chief Executive Officer | Mar 16, 2015 | Sale | $123.48 | 1,000 | 123,477 | 35,258 | Mar 18, 2015, 08:02 PM |
| BMRN | Chief Executive Officer | Mar 09, 2015 | Option Exercise | $12.99 | 15,000 | 194,850 | 57,279 | Mar 11, 2015, 06:32 PM |
| BMRN | Chief Executive Officer | Mar 10, 2015 | Sale | $114.89 | 2,021 | 232,201 | 36,258 | Mar 11, 2015, 06:32 PM |
| BMRN | Chief Executive Officer | Mar 09, 2015 | Sale | $112.13 | 19,000 | 2,130,391 | 42,279 | Mar 11, 2015, 06:32 PM |
| BMRN | Chief Executive Officer | Mar 05, 2015 | Option Exercise | $12.99 | 10,000 | 129,900 | 52,279 | Mar 05, 2015, 08:20 PM |
| BMRN | Chief Executive Officer | Mar 05, 2015 | Sale | $113.70 | 10,000 | 1,137,020 | 42,279 | Mar 05, 2015, 08:20 PM |
| BMRN | Chief Executive Officer | Mar 04, 2015 | Option Exercise | $9.86 | 500 | 4,930 | 43,695 | Mar 04, 2015, 07:39 PM |
| BMRN | Chief Executive Officer | Mar 02, 2015 | Option Exercise | $12.99 | 3,000 | 38,970 | 46,195 | Mar 04, 2015, 07:39 PM |
| BMRN | Chief Executive Officer | Mar 03, 2015 | Sale | $107.42 | 5,000 | 537,095 | 215,157 | Mar 04, 2015, 07:39 PM |
| BMRN | Chief Executive Officer | Mar 02, 2015 | Sale | $108.44 | 5,000 | 542,195 | 220,157 | Mar 04, 2015, 07:39 PM |
| BMRN | Chief Executive Officer | Mar 02, 2015 | Sale | $107.96 | 3,000 | 323,892 | 43,195 | Mar 04, 2015, 07:39 PM |
| BMRN | Chief Executive Officer | Mar 04, 2015 | Sale | $107.71 | 916 | 98,661 | 42,279 | Mar 04, 2015, 07:39 PM |
| BMRN | Chief Executive Officer | Jan 09, 2015 | Sale | $94.14 | 2,000 | 188,286 | 225,157 | Jan 13, 2015, 07:38 PM |
| BMRN | Chief Executive Officer | Dec 24, 2014 | Option Exercise | $12.99 | 3,000 | 38,970 | 46,195 | Dec 29, 2014, 07:21 PM |
| BMRN | Chief Executive Officer | Dec 24, 2014 | Sale | $88.73 | 2,000 | 177,462 | 227,157 | Dec 29, 2014, 07:21 PM |
| BMRN | Chief Executive Officer | Dec 24, 2014 | Sale | $88.73 | 3,000 | 266,193 | 43,195 | Dec 29, 2014, 07:21 PM |
| BMRN | Chief Executive Officer | Dec 10, 2014 | Option Exercise | $12.99 | 2,000 | 25,980 | 45,195 | Dec 12, 2014, 01:51 PM |
| BMRN | Chief Executive Officer | Dec 10, 2014 | Sale | $95.00 | 2,000 | 190,000 | 43,195 | Dec 12, 2014, 01:51 PM |
| BMRN | Chief Executive Officer | Nov 25, 2014 | Option Exercise | $12.99 | 2,000 | 25,980 | 45,195 | Nov 28, 2014, 09:24 PM |
| BMRN | Chief Executive Officer | Nov 25, 2014 | Sale | $90.00 | 2,000 | 180,000 | 43,195 | Nov 28, 2014, 09:24 PM |
| BMRN | Chief Executive Officer | Nov 12, 2014 | Sale | $85.51 | 1,000 | 85,513 | 228,157 | Nov 14, 2014, 03:05 PM |
| BMRN | Chief Executive Officer | Nov 12, 2014 | Sale | $81.51 | 1,000 | 81,513 | 228,157 | Nov 14, 2014, 02:58 PM |
| BMRN | Chief Executive Officer | Nov 10, 2014 | Option Exercise | $12.99 | 4,000 | 51,960 | 47,195 | Nov 12, 2014, 07:07 PM |
| BMRN | Chief Executive Officer | Nov 10, 2014 | Sale | $87.00 | 4,000 | 348,000 | 43,195 | Nov 12, 2014, 07:07 PM |
| BMRN | Chief Executive Officer | Nov 03, 2014 | Sale | $85.33 | 3,000 | 256,002 | 43,195 | Nov 05, 2014, 07:45 PM |
| BMRN | Chief Executive Officer | Oct 24, 2014 | Option Exercise | $12.99 | 2,000 | 25,980 | 48,195 | Oct 28, 2014, 07:09 PM |
| BMRN | Chief Executive Officer | Oct 24, 2014 | Sale | $80.00 | 2,000 | 160,000 | 46,195 | Oct 28, 2014, 07:09 PM |
| BMRN | Chief Executive Officer | Oct 21, 2014 | Option Exercise | $12.99 | 2,000 | 25,980 | 48,195 | Oct 23, 2014, 06:34 PM |
| BMRN | Chief Executive Officer | Oct 21, 2014 | Sale | $75.00 | 2,000 | 150,000 | 46,195 | Oct 23, 2014, 06:34 PM |
| VTL | Director | Oct 08, 2014 | Buy | $17.50 | 4,286 | 75,005 | 25,119 | Oct 09, 2014, 09:07 PM |
| ITMN | Director | Sep 29, 2014 | Option Exercise | $74.00 | 1,200 | 88,800 | 0 | Oct 01, 2014, 08:52 PM |
| ITMN | Director | Sep 29, 2014 | Option Exercise | $74.00 | 8,525 | 630,850 | 1,200 | Oct 01, 2014, 08:52 PM |
| BMRN | Chief Executive Officer | Aug 20, 2014 | Option Exercise | $12.99 | 5,000 | 64,950 | 51,195 | Aug 22, 2014, 08:10 PM |
| BMRN | Chief Executive Officer | Aug 20, 2014 | Sale | $70.00 | 5,000 | 350,000 | 46,195 | Aug 22, 2014, 08:10 PM |
| BMRN | Chief Executive Officer | Jun 04, 2014 | Sale | $62.52 | 1,000 | 62,521 | 178,257 | Jun 05, 2014, 07:33 PM |
| BMRN | Chief Executive Officer | Jun 03, 2014 | Sale | $59.88 | 1,000 | 59,876 | 179,257 | Jun 05, 2014, 07:33 PM |
| BMRN | Chief Executive Officer | May 22, 2014 | Sale | $56.88 | 1,000 | 56,876 | 46,195 | May 23, 2014, 12:57 PM |
| BMRN | Chief Executive Officer | May 21, 2014 | Sale | $56.19 | 1,545 | 86,817 | 47,195 | May 22, 2014, 06:27 PM |
| BMRN | Chief Executive Officer | May 15, 2014 | Option Exercise | $57.44 | 4,932 | 283,294 | 180,257 | May 19, 2014, 06:26 PM |
| PTLA | Director | May 16, 2014 | Sale | $22.03 | 1,000 | 22,030 | 706 | May 19, 2014, 04:43 PM |
| BMRN | Chief Executive Officer | May 12, 2014 | Option Exercise | $59.30 | 4,567 | 270,823 | 185,189 | May 14, 2014, 07:55 PM |
| BMRN | Chief Executive Officer | Apr 30, 2014 | Option Exercise | $29.69 | 715 | 21,228 | 195,235 | May 12, 2014, 04:58 PM |
| BMRN | Chief Executive Officer | May 08, 2014 | Option Exercise | $56.78 | 5,479 | 311,098 | 189,756 | May 12, 2014, 04:58 PM |
| VTL | Director | Apr 23, 2001 | Buy | $12.00 | 8,333 | 99,996 | 8,333 | Apr 23, 2014, 07:08 PM |
| BMRN | Chief Executive Officer | Mar 28, 2014 | Option Exercise | $12.99 | 2,000 | 25,980 | 48,740 | Apr 01, 2014, 07:41 PM |
| PTLA | Director | Mar 06, 2014 | Sale | $25.15 | 1,000 | 25,150 | 1,706 | Mar 10, 2014, 08:50 PM |
| PTLA | Director | May 22, 2013 | Buy | $14.50 | 2,000 | 29,000 | 2,000 | Mar 10, 2014, 08:47 PM |
| BMRN | Chief Executive Officer | Feb 20, 2014 | Sale | $80.00 | 8,000 | 640,000 | 46,740 | Feb 24, 2014, 06:54 PM |
| BMRN | Chief Executive Officer | Feb 06, 2014 | Option Exercise | $12.99 | 4,000 | 51,960 | 54,740 | Feb 07, 2014, 04:53 PM |
| BMRN | Chief Executive Officer | Jan 10, 2014 | Option Exercise | $12.99 | 5,000 | 64,950 | 55,740 | Jan 14, 2014, 07:37 PM |
| BMRN | Chief Executive Officer | Jan 10, 2014 | Sale | $70.00 | 5,000 | 350,000 | 50,740 | Jan 14, 2014, 07:37 PM |
| BMRN | Chief Executive Officer | Jan 06, 2014 | Option Exercise | $12.99 | 10,000 | 129,900 | 60,740 | Jan 08, 2014, 05:24 PM |
| BMRN | Chief Executive Officer | Jan 06, 2014 | Sale | $67.41 | 10,000 | 674,096 | 55,740 | Jan 08, 2014, 05:24 PM |
| BMRN | Chief Executive Officer | Jan 02, 2014 | Option Exercise | $12.99 | 5,000 | 64,950 | 55,740 | Jan 06, 2014, 04:08 PM |
| BMRN | Chief Executive Officer | Jan 02, 2014 | Sale | $68.90 | 5,000 | 344,482 | 50,740 | Jan 06, 2014, 04:08 PM |
| BMRN | Chief Executive Officer | Dec 24, 2013 | Option Exercise | $12.99 | 10,000 | 129,900 | 60,740 | Dec 27, 2013, 12:07 PM |
| BMRN | Chief Executive Officer | Dec 24, 2013 | Sale | $68.71 | 10,000 | 687,143 | 50,740 | Dec 27, 2013, 12:07 PM |
| BMRN | Chief Executive Officer | Dec 05, 2013 | Option Exercise | $12.99 | 5,000 | 64,950 | 55,740 | Dec 09, 2013, 07:42 PM |
| BMRN | Chief Executive Officer | Dec 05, 2013 | Sale | $69.70 | 5,000 | 348,484 | 50,740 | Dec 09, 2013, 07:42 PM |
| BMRN | Chief Executive Officer | Nov 14, 2013 | Option Exercise | $12.99 | 5,000 | 64,950 | 50,740 | Nov 18, 2013, 05:38 PM |
| BMRN | Chief Executive Officer | Nov 05, 2013 | Option Exercise | $12.99 | 5,000 | 64,950 | 50,740 | Nov 07, 2013, 05:33 PM |
| BMRN | Chief Executive Officer | Nov 05, 2013 | Sale | $62.36 | 5,000 | 311,779 | 45,740 | Nov 07, 2013, 05:33 PM |
| BMRN | Chief Executive Officer | Oct 31, 2013 | Option Exercise | $12.99 | 10,000 | 129,900 | 55,740 | Nov 04, 2013, 06:31 PM |
| BMRN | Chief Executive Officer | Oct 31, 2013 | Sale | $62.72 | 10,000 | 627,155 | 45,740 | Nov 04, 2013, 06:31 PM |
| BMRN | Chief Executive Officer | Oct 16, 2013 | Option Exercise | $12.99 | 2,000 | 25,980 | 47,740 | Oct 18, 2013, 05:15 PM |
| BMRN | Chief Executive Officer | Oct 16, 2013 | Sale | $67.72 | 2,000 | 135,450 | 45,740 | Oct 18, 2013, 05:15 PM |
| BMRN | Chief Executive Officer | Oct 10, 2013 | Sale | $66.76 | 3,000 | 200,291 | 45,740 | Oct 15, 2013, 08:17 PM |
| BMRN | Chief Executive Officer | Sep 16, 2013 | Option Exercise | $12.99 | 2,000 | 25,980 | 50,740 | Sep 18, 2013, 02:35 PM |
| BMRN | Chief Executive Officer | Sep 16, 2013 | Sale | $73.08 | 2,000 | 146,163 | 48,740 | Sep 18, 2013, 02:35 PM |
| BMRN | Chief Executive Officer | Aug 15, 2013 | Option Exercise | $12.99 | 1,000 | 12,990 | 49,740 | Aug 19, 2013, 05:10 PM |
| BMRN | Chief Executive Officer | Aug 15, 2013 | Sale | $64.36 | 1,000 | 64,364 | 48,740 | Aug 19, 2013, 05:10 PM |
| BMRN | Chief Executive Officer | Jul 15, 2013 | Option Exercise | $38.34 | 2,000 | 76,688 | 49,740 | Jul 17, 2013, 04:36 PM |
| BMRN | Chief Executive Officer | Jun 12, 2013 | Option Exercise | $12.99 | 5,000 | 64,950 | 48,740 | Jun 14, 2013, 06:51 PM |
| BMRN | Chief Executive Officer | Jun 05, 2013 | Option Exercise | $36.17 | 20,000 | 723,306 | 53,740 | Jun 07, 2013, 04:53 PM |
| BMRN | Chief Executive Officer | Jun 04, 2013 | Option Exercise | $36.85 | 20,000 | 737,094 | 53,740 | Jun 04, 2013, 05:47 PM |
| BMRN | Chief Executive Officer | May 31, 2013 | Option Exercise | $12.99 | 3,000 | 38,970 | 43,740 | Jun 04, 2013, 05:47 PM |
| BMRN | Chief Executive Officer | May 21, 2013 | Option Exercise | $12.99 | 2,000 | 25,980 | 32,609 | May 23, 2013, 06:03 PM |
| BMRN | Chief Executive Officer | May 21, 2013 | Sale | $64.14 | 2,000 | 128,279 | 30,609 | May 23, 2013, 06:03 PM |
| BMRN | Chief Executive Officer | May 12, 2013 | Option Exercise | $67.68 | 8,742 | 591,659 | 102,165 | May 23, 2013, 04:32 PM |
| BMRN | Chief Executive Officer | May 13, 2013 | Option Exercise | $12.99 | 8,000 | 103,920 | 28,609 | May 23, 2013, 04:32 PM |
| BMRN | Chief Executive Officer | May 10, 2013 | Sale | $67.48 | 800 | 53,985 | 111,038 | May 23, 2013, 04:32 PM |
| BMRN | Chief Executive Officer | May 13, 2013 | Sale | $69.11 | 8,000 | 552,896 | 25,609 | May 23, 2013, 04:32 PM |
| BMRN | Chief Executive Officer | May 13, 2013 | Sale | $68.53 | 7,000 | 479,720 | 97,165 | May 23, 2013, 04:32 PM |
| BMRN | Chief Executive Officer | May 16, 2013 | Option Exercise | $49.89 | 7,000 | 349,248 | 25,609 | May 17, 2013, 07:15 PM |
| BMRN | Chief Executive Officer | May 15, 2013 | Option Exercise | $12.99 | 10,000 | 129,900 | 30,609 | May 17, 2013, 07:15 PM |
| BMRN | Chief Executive Officer | May 17, 2013 | Option Exercise | $64.01 | 5,000 | 320,050 | 30,609 | May 17, 2013, 07:15 PM |
| BMRN | Chief Executive Officer | May 16, 2013 | Sale | $64.65 | 2,000 | 129,307 | 20,609 | May 17, 2013, 07:15 PM |
| BMRN | Chief Executive Officer | May 15, 2013 | Sale | $68.55 | 10,000 | 685,477 | 20,609 | May 17, 2013, 07:15 PM |
| BMRN | Chief Executive Officer | May 14, 2013 | Option Exercise | $12.99 | 15,000 | 194,850 | 35,609 | May 15, 2013, 02:45 PM |
| BMRN | Chief Executive Officer | May 14, 2013 | Sale | $70.17 | 15,000 | 1,052,491 | 20,609 | May 15, 2013, 02:45 PM |
| BMRN | Chief Executive Officer | May 14, 2013 | Option Exercise | $12.99 | 25,000 | 324,750 | 45,609 | May 15, 2013, 01:52 PM |
| BMRN | Chief Executive Officer | May 14, 2013 | Sale | $70.94 | 25,000 | 1,773,551 | 35,609 | May 15, 2013, 01:52 PM |
| BMRN | Chief Executive Officer | May 12, 2013 | Option Exercise | $67.68 | 8,873 | 600,525 | 102,165 | May 14, 2013, 02:21 PM |
| BMRN | Chief Executive Officer | May 13, 2013 | Option Exercise | $12.99 | 8,000 | 103,920 | 28,609 | May 14, 2013, 02:21 PM |
| BMRN | Chief Executive Officer | May 13, 2013 | Sale | $69.11 | 8,000 | 552,896 | 25,609 | May 14, 2013, 02:21 PM |
| BMRN | Chief Executive Officer | May 13, 2013 | Sale | $68.53 | 7,000 | 479,720 | 97,165 | May 14, 2013, 02:21 PM |
| BMRN | Chief Executive Officer | May 10, 2013 | Sale | $67.48 | 800 | 53,985 | 111,038 | May 14, 2013, 02:21 PM |
| BMRN | Chief Executive Officer | May 08, 2013 | Option Exercise | $65.32 | 5,479 | 357,888 | 112,838 | May 09, 2013, 05:59 PM |
| BMRN | Chief Executive Officer | May 07, 2013 | Option Exercise | $12.99 | 3,000 | 38,970 | 16,545 | May 09, 2013, 05:59 PM |
| BMRN | Chief Executive Officer | May 08, 2013 | Sale | $65.88 | 1,000 | 65,879 | 118,317 | May 09, 2013, 05:59 PM |
| BMRN | Chief Executive Officer | May 07, 2013 | Sale | $65.87 | 3,000 | 197,613 | 13,545 | May 09, 2013, 05:59 PM |
| BMRN | Chief Executive Officer | May 03, 2013 | Option Exercise | $12.99 | 8,000 | 103,920 | 18,545 | May 07, 2013, 04:10 PM |
| BMRN | Chief Executive Officer | May 03, 2013 | Sale | $67.24 | 8,000 | 537,950 | 13,545 | May 07, 2013, 04:10 PM |
| BMRN | Chief Executive Officer | Apr 30, 2013 | Option Exercise | $23.20 | 916 | 21,256 | 120,317 | May 02, 2013, 05:37 PM |
| BMRN | Chief Executive Officer | May 02, 2013 | Option Exercise | $12.99 | 2,000 | 25,980 | 15,545 | May 02, 2013, 05:37 PM |
| BMRN | Chief Executive Officer | Apr 30, 2013 | Sale | $63.74 | 1,000 | 63,742 | 119,317 | May 02, 2013, 05:37 PM |
| BMRN | Chief Executive Officer | May 02, 2013 | Sale | $65.62 | 2,000 | 131,241 | 13,545 | May 02, 2013, 05:37 PM |
| BMRN | Chief Executive Officer | Mar 26, 2013 | Option Exercise | $12.99 | 12,000 | 155,880 | 25,545 | Mar 28, 2013, 06:26 PM |
| BMRN | Chief Executive Officer | Mar 26, 2013 | Sale | $60.68 | 12,000 | 728,147 | 13,545 | Mar 28, 2013, 06:26 PM |
| BMRN | Chief Executive Officer | Mar 04, 2013 | Option Exercise | $12.99 | 5,000 | 64,950 | 23,545 | Mar 04, 2013, 08:58 PM |
| BMRN | Chief Executive Officer | Feb 28, 2013 | Option Exercise | $12.99 | 5,000 | 64,950 | 18,545 | Mar 04, 2013, 08:58 PM |
| BMRN | Chief Executive Officer | Feb 28, 2013 | Sale | $58.00 | 5,000 | 290,000 | 18,545 | Mar 04, 2013, 08:58 PM |
| BMRN | Chief Executive Officer | Mar 01, 2013 | Sale | $59.14 | 1,000 | 59,140 | 119,401 | Mar 04, 2013, 08:58 PM |
| BMRN | Chief Executive Officer | Mar 04, 2013 | Sale | $60.00 | 5,000 | 300,000 | 13,545 | Mar 04, 2013, 08:58 PM |
| BMRN | Chief Executive Officer | Feb 27, 2013 | Sale | $56.46 | 1,500 | 84,683 | 120,401 | Feb 28, 2013, 05:07 PM |
| BMRN | Chief Executive Officer | Feb 04, 2013 | Option Exercise | $12.99 | 2,000 | 25,980 | 155,691 | Feb 05, 2013, 05:30 PM |
| BMRN | Chief Executive Officer | Feb 04, 2013 | Sale | $55.77 | 2,000 | 111,532 | 153,691 | Feb 05, 2013, 05:30 PM |
| BMRN | Chief Executive Officer | Jan 23, 2013 | Sale | $55.22 | 4,000 | 220,880 | 153,691 | Jan 24, 2013, 07:54 PM |
| BMRN | Chief Executive Officer | Jan 22, 2013 | Sale | $55.00 | 10,000 | 550,000 | 157,691 | Jan 24, 2013, 07:54 PM |
| BMRN | Chief Executive Officer | Jan 18, 2013 | Option Exercise | $12.99 | 5,000 | 64,950 | 172,691 | Jan 23, 2013, 02:12 PM |
| BMRN | Chief Executive Officer | Jan 18, 2013 | Sale | $54.00 | 5,000 | 270,000 | 167,691 | Jan 23, 2013, 02:12 PM |
| BMRN | Chief Executive Officer | Jan 04, 2013 | Option Exercise | $12.99 | 3,000 | 38,970 | 170,691 | Jan 08, 2013, 07:43 PM |
| BMRN | Chief Executive Officer | Jan 04, 2013 | Sale | $52.24 | 3,000 | 156,731 | 167,691 | Jan 08, 2013, 07:43 PM |
| BMRN | Chief Executive Officer | Dec 31, 2012 | Option Exercise | $12.99 | 5,000 | 64,950 | 172,691 | Jan 03, 2013, 04:02 PM |
| BMRN | Chief Executive Officer | Dec 31, 2012 | Sale | $48.62 | 5,000 | 243,116 | 167,691 | Jan 03, 2013, 04:02 PM |
| BMRN | Chief Executive Officer | Dec 27, 2012 | Option Exercise | $12.99 | 4,000 | 51,960 | 184,691 | Dec 27, 2012, 07:59 PM |
| BMRN | Chief Executive Officer | Dec 26, 2012 | Option Exercise | $12.99 | 7,000 | 90,930 | 180,691 | Dec 27, 2012, 07:59 PM |
| BMRN | Chief Executive Officer | Dec 24, 2012 | Option Exercise | $12.99 | 6,000 | 77,940 | 173,691 | Dec 27, 2012, 07:59 PM |
| BMRN | Chief Executive Officer | Dec 26, 2012 | Sale | $48.38 | 7,000 | 338,633 | 171,691 | Dec 27, 2012, 07:59 PM |
| BMRN | Chief Executive Officer | Dec 24, 2012 | Sale | $48.38 | 6,000 | 290,252 | 178,691 | Dec 27, 2012, 07:59 PM |
| BMRN | Chief Executive Officer | Dec 27, 2012 | Sale | $48.34 | 4,000 | 193,360 | 167,691 | Dec 27, 2012, 07:59 PM |
| BMRN | Chief Executive Officer | Dec 21, 2012 | Option Exercise | $12.99 | 9,000 | 116,910 | 176,691 | Dec 21, 2012, 06:22 PM |
| BMRN | Chief Executive Officer | Dec 21, 2012 | Sale | $48.57 | 9,000 | 437,137 | 173,691 | Dec 21, 2012, 06:22 PM |
| BMRN | Chief Executive Officer | Dec 12, 2012 | Option Exercise | $12.99 | 5,000 | 64,950 | 172,691 | Dec 14, 2012, 06:24 PM |
| BMRN | Chief Executive Officer | Dec 12, 2012 | Sale | $50.00 | 5,000 | 250,000 | 167,691 | Dec 14, 2012, 06:24 PM |
| BMRN | Chief Executive Officer | Dec 07, 2012 | Option Exercise | $9.86 | 3,000 | 29,580 | 170,691 | Dec 11, 2012, 06:59 PM |
| BMRN | Chief Executive Officer | Dec 10, 2012 | Option Exercise | $12.99 | 3,000 | 38,970 | 170,691 | Dec 11, 2012, 06:59 PM |
| BMRN | Chief Executive Officer | Dec 10, 2012 | Sale | $48.03 | 3,000 | 144,084 | 167,691 | Dec 11, 2012, 06:59 PM |
| BMRN | Chief Executive Officer | Dec 07, 2012 | Sale | $47.04 | 3,000 | 141,123 | 167,691 | Dec 11, 2012, 06:59 PM |
| BMRN | Chief Executive Officer | Dec 04, 2012 | Option Exercise | $12.99 | 5,000 | 64,950 | 172,691 | Dec 06, 2012, 02:29 PM |
| BMRN | Chief Executive Officer | Dec 04, 2012 | Sale | $47.94 | 5,000 | 239,692 | 167,691 | Dec 06, 2012, 02:29 PM |
| BMRN | Chief Executive Officer | Nov 16, 2012 | Option Exercise | $12.99 | 8,000 | 103,920 | 175,691 | Nov 19, 2012, 06:18 PM |
| BMRN | Chief Executive Officer | Nov 16, 2012 | Sale | $48.05 | 8,000 | 384,366 | 167,691 | Nov 19, 2012, 06:18 PM |
| BMRN | Chief Executive Officer | Nov 09, 2012 | Sale | $48.42 | 2,000 | 96,844 | 167,691 | Nov 09, 2012, 08:16 PM |
| BMRN | Chief Executive Officer | Nov 07, 2012 | Sale | $47.29 | 5,000 | 236,470 | 172,691 | Nov 09, 2012, 08:16 PM |
| BMRN | Chief Executive Officer | Oct 31, 2012 | Option Exercise | $9.86 | 3,000 | 29,580 | 178,691 | Nov 01, 2012, 07:06 PM |
| BMRN | Chief Executive Officer | Oct 31, 2012 | Sale | $37.96 | 4,000 | 151,856 | 175,691 | Nov 01, 2012, 07:06 PM |
| BMRN | Chief Executive Officer | Oct 22, 2012 | Option Exercise | $9.86 | 3,000 | 29,580 | 178,691 | Oct 24, 2012, 08:33 PM |
| BMRN | Chief Executive Officer | Oct 22, 2012 | Sale | $41.86 | 3,000 | 125,579 | 175,691 | Oct 24, 2012, 08:33 PM |
| BMRN | Chief Executive Officer | Oct 19, 2012 | Sale | $42.72 | 2,000 | 85,440 | 175,691 | Oct 23, 2012, 12:20 PM |
| BMRN | Chief Executive Officer | Oct 12, 2012 | Option Exercise | $9.86 | 3,000 | 29,580 | 180,691 | Oct 16, 2012, 02:18 PM |
| BMRN | Chief Executive Officer | Oct 12, 2012 | Sale | $41.32 | 3,000 | 123,969 | 177,691 | Oct 16, 2012, 02:18 PM |
| BMRN | Chief Executive Officer | Sep 28, 2012 | Option Exercise | $9.86 | 4,000 | 39,440 | 181,691 | Oct 01, 2012, 09:21 PM |
| BMRN | Chief Executive Officer | Sep 28, 2012 | Sale | $40.20 | 4,000 | 160,804 | 177,691 | Oct 01, 2012, 09:21 PM |
| BMRN | Chief Executive Officer | Sep 14, 2012 | Option Exercise | $9.86 | 4,000 | 39,440 | 181,691 | Sep 17, 2012, 09:26 PM |
| BMRN | Chief Executive Officer | Sep 14, 2012 | Sale | $37.91 | 4,000 | 151,628 | 177,691 | Sep 17, 2012, 09:26 PM |
| BMRN | Chief Executive Officer | Sep 10, 2012 | Sale | $38.62 | 1,000 | 38,620 | 177,691 | Sep 12, 2012, 06:36 PM |
| ITMN | Director | Jun 04, 2012 | Option Exercise | $10.10 | 2,500 | 25,250 | 6,725 | Jun 06, 2012, 07:01 PM |
| BMRN | Chief Executive Officer | May 31, 2012 | Option Exercise | $6.46 | 2,000 | 12,920 | 178,691 | May 31, 2012, 07:19 PM |
| BMRN | Chief Executive Officer | May 31, 2012 | Option Exercise | $6.46 | 8,000 | 51,680 | 176,691 | May 31, 2012, 03:46 PM |
| BMRN | Chief Executive Officer | May 16, 2012 | Option Exercise | $9.86 | 15,000 | 147,900 | 183,691 | May 18, 2012, 06:20 PM |
| BMRN | Chief Executive Officer | May 16, 2012 | Sale | $38.49 | 15,000 | 577,369 | 173,691 | May 18, 2012, 06:20 PM |
| BMRN | Chief Executive Officer | May 11, 2012 | Option Exercise | $8.50 | 25,000 | 212,500 | 194,191 | May 15, 2012, 08:11 PM |
| BMRN | Chief Executive Officer | May 14, 2012 | Option Exercise | $9.86 | 15,000 | 147,900 | 183,691 | May 15, 2012, 08:11 PM |
| BMRN | Chief Executive Officer | May 14, 2012 | Sale | $38.13 | 15,000 | 571,893 | 168,691 | May 15, 2012, 08:11 PM |
| BMRN | Chief Executive Officer | May 11, 2012 | Sale | $38.03 | 25,500 | 969,656 | 174,191 | May 15, 2012, 08:11 PM |
| BMRN | Chief Executive Officer | May 08, 2012 | Option Exercise | $9.86 | 15,000 | 147,900 | 128,191 | May 09, 2012, 04:39 PM |
| BMRN | Chief Executive Officer | May 07, 2012 | Option Exercise | $9.86 | 5,000 | 49,300 | 118,191 | May 09, 2012, 04:39 PM |
| BMRN | Chief Executive Officer | May 08, 2012 | Sale | $36.52 | 15,000 | 547,800 | 113,191 | May 09, 2012, 04:39 PM |
| BMRN | Chief Executive Officer | May 07, 2012 | Sale | $35.96 | 5,000 | 179,800 | 113,191 | May 09, 2012, 04:39 PM |
| BMRN | Chief Executive Officer | May 03, 2012 | Option Exercise | $9.86 | 10,000 | 98,600 | 123,191 | May 04, 2012, 05:54 PM |
| BMRN | Chief Executive Officer | May 04, 2012 | Option Exercise | $9.86 | 10,000 | 98,600 | 123,191 | May 04, 2012, 05:54 PM |
| BMRN | Chief Executive Officer | May 03, 2012 | Sale | $36.68 | 10,000 | 366,800 | 113,191 | May 04, 2012, 05:54 PM |
| BMRN | Chief Executive Officer | May 04, 2012 | Sale | $36.00 | 10,000 | 360,000 | 113,191 | May 04, 2012, 05:54 PM |
| BMRN | Chief Executive Officer | Apr 30, 2012 | Option Exercise | $19.35 | 1,098 | 21,242 | 113,191 | May 03, 2012, 02:23 PM |
| BMRN | Chief Executive Officer | May 02, 2012 | Option Exercise | $9.86 | 10,000 | 98,600 | 123,191 | May 03, 2012, 02:23 PM |
| BMRN | Chief Executive Officer | May 01, 2012 | Option Exercise | $9.86 | 20,000 | 197,200 | 133,191 | May 03, 2012, 02:23 PM |
| BMRN | Chief Executive Officer | May 02, 2012 | Sale | $35.72 | 10,000 | 357,200 | 113,191 | May 03, 2012, 02:23 PM |
| BMRN | Chief Executive Officer | May 01, 2012 | Sale | $35.00 | 20,000 | 699,920 | 113,191 | May 03, 2012, 02:23 PM |
| BMRN | Chief Executive Officer | Apr 27, 2012 | Option Exercise | $9.86 | 20,000 | 197,200 | 134,093 | Apr 30, 2012, 05:56 PM |
| BMRN | Chief Executive Officer | Apr 27, 2012 | Sale | $34.99 | 22,000 | 769,872 | 114,093 | Apr 30, 2012, 05:56 PM |
| BMRN | Chief Executive Officer | Mar 09, 2012 | Option Exercise | $6.47 | 15,000 | 97,050 | 129,093 | Mar 13, 2012, 08:53 AM |
| BMRN | Chief Executive Officer | Mar 09, 2012 | Sale | $34.46 | 15,000 | 516,867 | 114,093 | Mar 13, 2012, 08:53 AM |
| BMRN | Chief Executive Officer | Mar 08, 2012 | Sale | $35.00 | 1,000 | 35,000 | 114,093 | Mar 09, 2012, 01:16 PM |
| BMRN | Chief Executive Officer | Feb 29, 2012 | Sale | $36.26 | 1,000 | 36,258 | 115,093 | Mar 01, 2012, 05:23 PM |
| BMRN | Chief Executive Officer | Feb 27, 2012 | Sale | $35.94 | 3,000 | 107,813 | 116,093 | Feb 28, 2012, 03:51 PM |
| BMRN | Chief Executive Officer | Feb 24, 2012 | Sale | $35.20 | 2,000 | 70,396 | 119,093 | Feb 28, 2012, 03:51 PM |
| BMRN | Chief Executive Officer | Feb 23, 2012 | Sale | $35.31 | 5,000 | 176,541 | 121,093 | Feb 24, 2012, 06:55 PM |
| BMRN | Chief Executive Officer | Sep 28, 2011 | Sale | $32.00 | 1,000 | 32,000 | 126,093 | Sep 30, 2011, 12:37 PM |
| BMRN | Chief Executive Officer | Aug 30, 2011 | Option Exercise | $6.46 | 2,000 | 12,920 | 129,093 | Aug 31, 2011, 03:39 PM |
| BMRN | Chief Executive Officer | Aug 30, 2011 | Sale | $29.01 | 2,000 | 58,018 | 127,093 | Aug 31, 2011, 03:39 PM |
| BMRN | Chief Executive Officer | Aug 19, 2011 | Option Exercise | $6.46 | 2,000 | 12,920 | 129,093 | Aug 22, 2011, 06:43 PM |
| BMRN | Chief Executive Officer | Aug 19, 2011 | Sale | $26.75 | 2,000 | 53,496 | 127,093 | Aug 22, 2011, 06:43 PM |
| BMRN | Chief Executive Officer | Aug 12, 2011 | Option Exercise | $6.46 | 3,000 | 19,380 | 130,093 | Aug 16, 2011, 12:35 PM |
| BMRN | Chief Executive Officer | Aug 12, 2011 | Sale | $27.10 | 3,000 | 81,288 | 127,093 | Aug 16, 2011, 12:35 PM |
| BMRN | Chief Executive Officer | Aug 02, 2011 | Option Exercise | $6.46 | 4,000 | 25,840 | 135,093 | Aug 04, 2011, 01:54 PM |
| BMRN | Chief Executive Officer | Aug 02, 2011 | Sale | $30.27 | 8,000 | 242,136 | 131,093 | Aug 04, 2011, 01:54 PM |
| NGSX | Director | Jul 26, 2011 | Option Exercise | $1.65 | 11,627 | 19,185 | 21,748 | Jul 26, 2011, 08:56 PM |
| BMRN | Chief Executive Officer | Jul 14, 2011 | Sale | $30.00 | 1,000 | 30,000 | 131,093 | Jul 18, 2011, 05:43 PM |
| BMRN | Chief Executive Officer | Jun 06, 2011 | Sale | $27.39 | 2,000 | 54,772 | 127,093 | Jun 08, 2011, 04:14 PM |
| BMRN | Chief Executive Officer | May 31, 2011 | Sale | $28.00 | 710 | 19,880 | 129,093 | Jun 02, 2011, 04:54 PM |
| BMRN | Chief Executive Officer | May 27, 2011 | Sale | $28.00 | 290 | 8,120 | 129,803 | May 31, 2011, 01:59 PM |
| BMRN | Chief Executive Officer | May 25, 2011 | Sale | $26.94 | 1,000 | 26,944 | 130,093 | May 31, 2011, 01:58 PM |
| BMRN | Chief Executive Officer | May 25, 2011 | Sale | $26.94 | 1,000 | 26,944 | 103,093 | May 26, 2011, 08:32 PM |
| BMRN | Chief Executive Officer | May 10, 2011 | Sale | $25.87 | 400 | 10,346 | 87,593 | May 12, 2011, 03:15 PM |
| BMRN | Chief Executive Officer | May 05, 2011 | Sale | $25.64 | 200 | 5,128 | 87,993 | May 09, 2011, 01:10 PM |
| BMRN | Chief Executive Officer | Apr 29, 2011 | Option Exercise | $11.64 | 1,826 | 21,249 | 91,893 | May 05, 2011, 02:52 PM |
| BMRN | Chief Executive Officer | May 04, 2011 | Option Exercise | $9.86 | 1,000 | 9,860 | 90,893 | May 05, 2011, 02:52 PM |
| BMRN | Chief Executive Officer | May 03, 2011 | Option Exercise | $9.86 | 3,000 | 29,580 | 94,893 | May 05, 2011, 02:52 PM |
| BMRN | Chief Executive Officer | May 04, 2011 | Sale | $26.13 | 2,700 | 70,547 | 89,893 | May 05, 2011, 02:52 PM |
| BMRN | Chief Executive Officer | May 03, 2011 | Sale | $26.85 | 5,000 | 134,266 | 91,893 | May 05, 2011, 02:52 PM |
| BMRN | Chief Executive Officer | Jan 18, 2011 | Sale | $26.58 | 3,500 | 93,030 | 90,067 | Jan 19, 2011, 05:31 PM |
| BMRN | Chief Executive Officer | Dec 13, 2010 | Option Exercise | $6.46 | 1,000 | 6,460 | 94,567 | Dec 13, 2010, 04:30 PM |
| BMRN | Chief Executive Officer | Dec 13, 2010 | Sale | $27.43 | 1,000 | 27,429 | 93,567 | Dec 13, 2010, 04:30 PM |
| BMRN | Chief Executive Officer | Dec 06, 2010 | Option Exercise | $6.46 | 2,000 | 12,920 | 95,567 | Dec 13, 2010, 02:45 PM |
| BMRN | Chief Executive Officer | Dec 06, 2010 | Sale | $27.17 | 2,000 | 54,348 | 93,567 | Dec 13, 2010, 02:45 PM |
| BMRN | Chief Executive Officer | Dec 06, 2010 | Option Exercise | $6.46 | 1,000 | 6,460 | 94,567 | Dec 07, 2010, 03:44 PM |
| BMRN | Chief Executive Officer | Dec 06, 2010 | Sale | $27.17 | 1,000 | 27,174 | 93,567 | Dec 07, 2010, 03:44 PM |
| BMRN | Chief Executive Officer | Nov 23, 2010 | Option Exercise | $6.46 | 1,000 | 6,460 | 94,567 | Nov 23, 2010, 08:11 PM |
| BMRN | Chief Executive Officer | Nov 23, 2010 | Sale | $27.02 | 1,000 | 27,021 | 93,567 | Nov 23, 2010, 08:11 PM |
| BMRN | Chief Executive Officer | Nov 18, 2010 | Option Exercise | $6.46 | 1,000 | 6,460 | 94,567 | Nov 22, 2010, 02:44 PM |
| BMRN | Chief Executive Officer | Nov 18, 2010 | Sale | $25.99 | 1,000 | 25,988 | 93,567 | Nov 22, 2010, 02:44 PM |
| BMRN | Chief Executive Officer | Nov 08, 2010 | Option Exercise | $6.46 | 2,000 | 12,920 | 95,567 | Nov 09, 2010, 05:14 PM |
| BMRN | Chief Executive Officer | Nov 08, 2010 | Sale | $25.78 | 2,000 | 51,569 | 93,567 | Nov 09, 2010, 05:14 PM |
| BMRN | Chief Executive Officer | Nov 02, 2010 | Option Exercise | $6.46 | 2,000 | 12,920 | 97,067 | Nov 04, 2010, 03:39 PM |
| BMRN | Chief Executive Officer | Nov 03, 2010 | Option Exercise | $6.46 | 4,000 | 25,840 | 97,567 | Nov 04, 2010, 03:39 PM |
| BMRN | Chief Executive Officer | Nov 02, 2010 | Sale | $25.64 | 3,500 | 89,750 | 95,067 | Nov 04, 2010, 03:39 PM |
| BMRN | Chief Executive Officer | Nov 03, 2010 | Sale | $25.46 | 4,000 | 101,824 | 93,567 | Nov 04, 2010, 03:39 PM |
| BMRN | Chief Executive Officer | Sep 08, 2010 | Option Exercise | $6.46 | 1,000 | 6,460 | 96,067 | Sep 09, 2010, 07:51 PM |
| BMRN | Chief Executive Officer | Sep 08, 2010 | Sale | $22.22 | 1,000 | 22,220 | 95,067 | Sep 09, 2010, 07:51 PM |
| BMRN | Chief Executive Officer | Sep 02, 2010 | Sale | $20.89 | 1,000 | 20,890 | 95,067 | Sep 02, 2010, 07:27 PM |
| BMRN | Chief Executive Officer | Sep 01, 2010 | Sale | $21.00 | 3,000 | 63,000 | 96,067 | Sep 02, 2010, 07:27 PM |
| BMRN | Chief Executive Officer | Aug 30, 2010 | Option Exercise | $6.46 | 3,000 | 19,380 | 102,067 | Sep 01, 2010, 06:45 PM |
| BMRN | Chief Executive Officer | Aug 30, 2010 | Sale | $20.71 | 3,000 | 62,125 | 99,067 | Sep 01, 2010, 06:45 PM |
| BMRN | Chief Executive Officer | Aug 27, 2010 | Option Exercise | $6.46 | 3,000 | 19,380 | 102,067 | Sep 01, 2010, 06:38 PM |
| BMRN | Chief Executive Officer | Aug 27, 2010 | Sale | $20.68 | 3,000 | 62,028 | 99,067 | Sep 01, 2010, 06:38 PM |
| BMRN | Chief Executive Officer | Aug 30, 2010 | Option Exercise | $6.46 | 3,000 | 19,380 | 102,067 | Aug 31, 2010, 01:58 PM |
| BMRN | Chief Executive Officer | Aug 30, 2010 | Sale | $20.71 | 3,000 | 62,125 | 99,067 | Aug 31, 2010, 01:58 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| BMRN | Chief Executive Officer | Aug 08, 2023 | Sale | 529,740 |
| BMRN | Chief Executive Officer | Aug 07, 2023 | Sale | 352,400 |
| BMRN | Chief Executive Officer | May 12, 2023 | Option Exercise | 3,755,415 |
| BMRN | Chief Executive Officer | May 12, 2023 | Option Exercise | 3,153,165 |
| BMRN | Chief Executive Officer | May 11, 2023 | Option Exercise | 2,034,300 |
| BMRN | Chief Executive Officer | May 11, 2023 | Sale | 2,840,226 |
| BMRN | Chief Executive Officer | Apr 28, 2023 | Option Exercise | 21,201 |
| BMRN | Chief Executive Officer | May 09, 2023 | Option Exercise | 2,034,300 |
| BMRN | Chief Executive Officer | May 10, 2023 | Option Exercise | 2,034,300 |
| BMRN | Chief Executive Officer | May 10, 2023 | Sale | 2,845,397 |
| BMRN | Chief Executive Officer | May 09, 2023 | Sale | 2,847,973 |
| BMRN | Chief Executive Officer | Apr 10, 2023 | Option Exercise | 678,100 |
| BMRN | Chief Executive Officer | Apr 10, 2023 | Sale | 995,600 |
| BMRN | Chief Executive Officer | Apr 06, 2023 | Option Exercise | 678,100 |
| BMRN | Chief Executive Officer | Apr 06, 2023 | Sale | 961,300 |
| BMRN | Chief Executive Officer | Mar 15, 2023 | Option Exercise | 828,002 |
| BMRN | Chief Executive Officer | Mar 16, 2023 | Option Exercise | 8,278,275 |
| BMRN | Chief Executive Officer | Mar 13, 2023 | Option Exercise | 542,480 |
| BMRN | Chief Executive Officer | Mar 10, 2023 | Option Exercise | 1,017,150 |
| BMRN | Chief Executive Officer | Mar 13, 2023 | Sale | 723,600 |
| BMRN | Chief Executive Officer | Mar 10, 2023 | Sale | 1,384,200 |
| BMRN | Chief Executive Officer | Feb 10, 2023 | Option Exercise | 1,017,150 |
| BMRN | Chief Executive Officer | Feb 13, 2023 | Option Exercise | 406,860 |
| BMRN | Chief Executive Officer | Feb 10, 2023 | Sale | 1,651,650 |
| BMRN | Chief Executive Officer | Feb 13, 2023 | Sale | 654,900 |
| BMRN | Chief Executive Officer | Jan 17, 2023 | Option Exercise | 678,100 |
| BMRN | Chief Executive Officer | Jan 13, 2023 | Option Exercise | 678,100 |
| BMRN | Chief Executive Officer | Jan 17, 2023 | Sale | 1,115,500 |
| BMRN | Chief Executive Officer | Jan 13, 2023 | Sale | 1,122,500 |
| BMRN | Chief Executive Officer | Dec 13, 2022 | Sale | 106,890 |
| BMRN | Chief Executive Officer | Nov 02, 2022 | Option Exercise | 8,612 |
| BMRN | Chief Executive Officer | Dec 02, 2022 | Sale | 155,967 |
| BMRN | Chief Executive Officer | Oct 31, 2022 | Sale | 129,825 |
| BMRN | Chief Executive Officer | Oct 14, 2022 | Sale | 359,560 |
| BMRN | Chief Executive Officer | Aug 15, 2022 | Sale | 285,630 |
| BMRN | Chief Executive Officer | Aug 12, 2022 | Sale | 379,000 |
| BMRN | Chief Executive Officer | Apr 29, 2022 | Option Exercise | 21,281 |
| BMRN | Chief Executive Officer | May 06, 2022 | Option Exercise | 749,200 |
| BMRN | Chief Executive Officer | May 05, 2022 | Option Exercise | 374,600 |
| BMRN | Chief Executive Officer | May 06, 2022 | Sale | 1,620,000 |
| BMRN | Chief Executive Officer | May 05, 2022 | Sale | 841,400 |
| BMRN | Chief Executive Officer | Apr 29, 2022 | Option Exercise | 187,300 |
| BMRN | Chief Executive Officer | Apr 28, 2022 | Option Exercise | 749,200 |
| BMRN | Chief Executive Officer | Apr 28, 2022 | Sale | 1,675,800 |
| BMRN | Chief Executive Officer | Apr 29, 2022 | Sale | 409,750 |
| BMRN | Chief Executive Officer | Apr 18, 2022 | Option Exercise | 749,200 |
| BMRN | Chief Executive Officer | Apr 18, 2022 | Sale | 1,638,200 |
| BMRN | Chief Executive Officer | Apr 14, 2022 | Option Exercise | 374,600 |
| BMRN | Chief Executive Officer | Apr 14, 2022 | Sale | 836,600 |
| BMRN | Chief Executive Officer | Mar 16, 2022 | Option Exercise | 448,803 |
| BMRN | Chief Executive Officer | Mar 15, 2022 | Option Exercise | 2,998,210 |
| BMRN | Chief Executive Officer | Mar 11, 2022 | Option Exercise | 561,900 |
| BMRN | Chief Executive Officer | Mar 10, 2022 | Option Exercise | 561,900 |
| BMRN | Chief Executive Officer | Mar 11, 2022 | Sale | 1,167,150 |
| BMRN | Chief Executive Officer | Mar 10, 2022 | Sale | 1,163,550 |
| BMRN | Chief Executive Officer | Dec 21, 2021 | Option Exercise | 8,922 |
| BMRN | Chief Executive Officer | Jan 13, 2022 | Option Exercise | 187,300 |
| BMRN | Chief Executive Officer | Jan 12, 2022 | Option Exercise | 187,300 |
| BMRN | Chief Executive Officer | Jan 13, 2022 | Sale | 439,300 |
| BMRN | Chief Executive Officer | Jan 12, 2022 | Sale | 445,000 |
| BMRN | Chief Executive Officer | Dec 16, 2021 | Option Exercise | 224,760 |
| BMRN | Chief Executive Officer | Dec 15, 2021 | Option Exercise | 224,760 |
| BMRN | Chief Executive Officer | Dec 15, 2021 | Sale | 496,260 |
| BMRN | Chief Executive Officer | Dec 16, 2021 | Sale | 508,080 |
| BMRN | Chief Executive Officer | Sep 09, 2021 | Option Exercise | 3,938 |
| BMRN | Chief Executive Officer | Dec 01, 2021 | Sale | 130,832 |
| BMRN | Chief Executive Officer | Oct 20, 2021 | Option Exercise | 37,460 |
| BMRN | Chief Executive Officer | Jun 21, 2021 | Option Exercise | 37,460 |
| BMRN | Chief Executive Officer | May 10, 2021 | Option Exercise | 225,509 |
| BMRN | Chief Executive Officer | May 10, 2021 | Sale | 657,970 |
| BMRN | Chief Executive Officer | Apr 30, 2021 | Option Exercise | 21,281 |
| BMRN | Chief Executive Officer | May 07, 2021 | Option Exercise | 662,250 |
| BMRN | Chief Executive Officer | May 06, 2021 | Option Exercise | 662,250 |
| BMRN | Chief Executive Officer | May 07, 2021 | Sale | 1,953,121 |
| BMRN | Chief Executive Officer | May 06, 2021 | Sale | 1,957,199 |
| BMRN | Chief Executive Officer | Apr 23, 2021 | Option Exercise | 264,900 |
| BMRN | Chief Executive Officer | Apr 22, 2021 | Option Exercise | 264,900 |
| BMRN | Chief Executive Officer | Apr 23, 2021 | Sale | 793,400 |
| BMRN | Chief Executive Officer | Apr 22, 2021 | Sale | 789,100 |
| BMRN | Chief Executive Officer | Mar 22, 2021 | Option Exercise | 433,352 |
| BMRN | Chief Executive Officer | Mar 15, 2021 | Option Exercise | 1,836,364 |
| BMRN | Chief Executive Officer | Mar 16, 2021 | Option Exercise | 429,210 |
| BMRN | Chief Executive Officer | Mar 04, 2021 | Option Exercise | 7,794 |
| BMRN | Chief Executive Officer | Mar 12, 2021 | Option Exercise | 185,430 |
| BMRN | Chief Executive Officer | Mar 11, 2021 | Option Exercise | 185,430 |
| BMRN | Chief Executive Officer | Mar 12, 2021 | Sale | 539,700 |
| BMRN | Chief Executive Officer | Mar 11, 2021 | Sale | 543,760 |
| BMRN | Chief Executive Officer | Feb 19, 2021 | Option Exercise | 185,430 |
| BMRN | Chief Executive Officer | Feb 19, 2021 | Sale | 585,060 |
| BMRN | Chief Executive Officer | Feb 18, 2021 | Option Exercise | 185,430 |
| BMRN | Chief Executive Officer | Feb 18, 2021 | Sale | 595,560 |
| BMRN | Chief Executive Officer | Feb 17, 2021 | Option Exercise | 211,920 |
| BMRN | Chief Executive Officer | Feb 17, 2021 | Sale | 676,320 |
| BMRN | Chief Executive Officer | Jan 29, 2021 | Option Exercise | 220,768 |
| BMRN | Chief Executive Officer | Jan 28, 2021 | Option Exercise | 220,741 |
| BMRN | Chief Executive Officer | Jan 28, 2021 | Sale | 690,889 |
| BMRN | Chief Executive Officer | Jan 29, 2021 | Sale | 688,972 |
| BMRN | Chief Executive Officer | Jan 27, 2021 | Option Exercise | 220,741 |
| BMRN | Chief Executive Officer | Jan 27, 2021 | Sale | 712,388 |
| INCY | Director | Dec 31, 2020 | Option Exercise | 23,920 |
| BMRN | Chief Executive Officer | Dec 28, 2020 | Sale | 133,155 |
| BMRN | Chief Executive Officer | Dec 29, 2020 | Sale | 132,270 |
| INCY | Director | Nov 10, 2020 | Sale | 66,234 |
| INCY | Director | Sep 30, 2020 | Option Exercise | 22,794 |
| INCY | Director | Jun 30, 2020 | Option Exercise | 21,626 |
| BMRN | Chief Executive Officer | May 08, 2020 | Option Exercise | 430,200 |
| BMRN | Chief Executive Officer | May 08, 2020 | Sale | 1,834,400 |
| BMRN | Chief Executive Officer | Apr 30, 2020 | Option Exercise | 21,217 |
| BMRN | Chief Executive Officer | May 04, 2020 | Option Exercise | 107,550 |
| BMRN | Chief Executive Officer | May 01, 2020 | Option Exercise | 86,040 |
| BMRN | Chief Executive Officer | May 04, 2020 | Sale | 440,000 |
| BMRN | Chief Executive Officer | May 01, 2020 | Sale | 357,520 |
| BMRN | Chief Executive Officer | Apr 28, 2020 | Option Exercise | 430,200 |
| BMRN | Chief Executive Officer | Apr 27, 2020 | Option Exercise | 430,200 |
| BMRN | Chief Executive Officer | Apr 27, 2020 | Sale | 1,954,600 |
| BMRN | Chief Executive Officer | Apr 28, 2020 | Sale | 1,951,600 |
| BMRN | Chief Executive Officer | Apr 09, 2020 | Option Exercise | 215,100 |
| BMRN | Chief Executive Officer | Apr 09, 2020 | Sale | 790,600 |
| BMRN | Chief Executive Officer | Apr 07, 2020 | Option Exercise | 26,490 |
| INCY | Director | Mar 31, 2020 | Option Exercise | 17,282 |
| BMRN | Chief Executive Officer | Mar 20, 2020 | Option Exercise | 959,000 |
| BMRN | Chief Executive Officer | Mar 13, 2020 | Option Exercise | 2,615,444 |
| BMRN | Chief Executive Officer | Mar 03, 2020 | Option Exercise | 2,832 |
| BMRN | Chief Executive Officer | Mar 09, 2020 | Option Exercise | 215,100 |
| BMRN | Chief Executive Officer | Mar 09, 2020 | Sale | 895,200 |
| BMRN | Chief Executive Officer | Feb 03, 2020 | Option Exercise | 215,100 |
| BMRN | Chief Executive Officer | Feb 03, 2020 | Sale | 835,000 |
| BMRN | Chief Executive Officer | Jan 30, 2020 | Option Exercise | 21,510 |
| BMRN | Chief Executive Officer | Jan 14, 2020 | Option Exercise | 172,080 |
| BMRN | Chief Executive Officer | Jan 14, 2020 | Sale | 703,600 |
| BMRN | Chief Executive Officer | Jan 07, 2020 | Option Exercise | 64,530 |
| BMRN | Chief Executive Officer | Jan 08, 2020 | Option Exercise | 86,040 |
| BMRN | Chief Executive Officer | Jan 08, 2020 | Sale | 339,680 |
| BMRN | Chief Executive Officer | Jan 07, 2020 | Sale | 253,380 |
| INCY | Director | Dec 31, 2019 | Option Exercise | 16,591 |
| BMRN | Chief Executive Officer | Dec 27, 2019 | Option Exercise | 107,550 |
| BMRN | Chief Executive Officer | Dec 26, 2019 | Option Exercise | 64,530 |
| BMRN | Chief Executive Officer | Dec 27, 2019 | Sale | 430,800 |
| BMRN | Chief Executive Officer | Dec 26, 2019 | Sale | 259,290 |
| BMRN | Chief Executive Officer | Nov 11, 2019 | Option Exercise | 754 |
| BMRN | Chief Executive Officer | Nov 22, 2019 | Option Exercise | 215,100 |
| BMRN | Chief Executive Officer | Nov 22, 2019 | Sale | 776,000 |
| BMRN | Chief Executive Officer | Oct 25, 2019 | Option Exercise | 107,550 |
| BMRN | Chief Executive Officer | Oct 25, 2019 | Sale | 347,750 |
| INCY | Director | Sep 30, 2019 | Option Exercise | 16,256 |
| BMRN | Chief Executive Officer | Sep 27, 2019 | Option Exercise | 21,510 |
| INCY | Director | Aug 02, 2019 | Sale | 31,943 |
| INCY | Director | Aug 01, 2019 | Sale | 114,711 |
| INCY | Director | Jun 28, 2019 | Option Exercise | 16,567 |
| BMRN | Chief Executive Officer | May 10, 2019 | Option Exercise | 143,900 |
| BMRN | Chief Executive Officer | May 10, 2019 | Sale | 825,193 |
| BMRN | Chief Executive Officer | May 09, 2019 | Option Exercise | 57,560 |
| BMRN | Chief Executive Officer | May 09, 2019 | Sale | 327,888 |
| BMRN | Chief Executive Officer | Apr 30, 2019 | Option Exercise | 21,254 |
| BMRN | Chief Executive Officer | May 08, 2019 | Option Exercise | 57,560 |
| BMRN | Chief Executive Officer | May 08, 2019 | Sale | 328,625 |
| BMRN | Chief Executive Officer | Apr 26, 2019 | Option Exercise | 43,170 |
| BMRN | Chief Executive Officer | Apr 26, 2019 | Sale | 248,640 |
| BMRN | Chief Executive Officer | Apr 16, 2019 | Option Exercise | 21,510 |
| BMRN | Chief Executive Officer | Apr 12, 2019 | Option Exercise | 57,560 |
| BMRN | Chief Executive Officer | Apr 11, 2019 | Option Exercise | 14,390 |
| BMRN | Chief Executive Officer | Apr 12, 2019 | Sale | 356,480 |
| BMRN | Chief Executive Officer | Apr 08, 2019 | Option Exercise | 43,170 |
| BMRN | Chief Executive Officer | Apr 08, 2019 | Sale | 275,598 |
| BMRN | Chief Executive Officer | Apr 05, 2019 | Option Exercise | 43,170 |
| BMRN | Chief Executive Officer | Apr 05, 2019 | Sale | 280,114 |
| INCY | Director | Mar 29, 2019 | Option Exercise | 14,450 |
| BMRN | Chief Executive Officer | Mar 27, 2019 | Option Exercise | 14,390 |
| BMRN | Chief Executive Officer | Mar 22, 2019 | Option Exercise | 1,155,832 |
| BMRN | Chief Executive Officer | Mar 25, 2019 | Option Exercise | 57,560 |
| BMRN | Chief Executive Officer | Mar 25, 2019 | Sale | 351,440 |
| BMRN | Chief Executive Officer | Mar 19, 2019 | Option Exercise | 14,390 |
| BMRN | Chief Executive Officer | Mar 15, 2019 | Option Exercise | 2,660,358 |
| BMRN | Chief Executive Officer | Mar 15, 2019 | Option Exercise | 57,560 |
| BMRN | Chief Executive Officer | Mar 15, 2019 | Sale | 377,600 |
| BMRN | Chief Executive Officer | Mar 13, 2019 | Option Exercise | 43,170 |
| BMRN | Chief Executive Officer | Mar 13, 2019 | Sale | 280,253 |
| BMRN | Chief Executive Officer | Mar 12, 2019 | Option Exercise | 57,560 |
| BMRN | Chief Executive Officer | Mar 11, 2019 | Option Exercise | 71,950 |
| BMRN | Chief Executive Officer | Mar 12, 2019 | Sale | 365,770 |
| BMRN | Chief Executive Officer | Mar 11, 2019 | Sale | 444,780 |
| BMRN | Chief Executive Officer | Mar 07, 2019 | Option Exercise | 57,560 |
| BMRN | Chief Executive Officer | Mar 07, 2019 | Sale | 363,120 |
| BMRN | Chief Executive Officer | Mar 01, 2019 | Option Exercise | 465,177 |
| BMRN | Chief Executive Officer | Feb 27, 2019 | Option Exercise | 57,560 |
| BMRN | Chief Executive Officer | Feb 27, 2019 | Sale | 367,120 |
| BMRN | Chief Executive Officer | Feb 21, 2019 | Option Exercise | 43,170 |
| BMRN | Chief Executive Officer | Feb 21, 2019 | Sale | 270,360 |
| BMRN | Chief Executive Officer | Feb 14, 2019 | Option Exercise | 57,560 |
| BMRN | Chief Executive Officer | Feb 14, 2019 | Sale | 380,800 |
| BMRN | Chief Executive Officer | Feb 05, 2019 | Option Exercise | 57,560 |
| BMRN | Chief Executive Officer | Feb 05, 2019 | Sale | 394,520 |
| BMRN | Chief Executive Officer | Jan 22, 2019 | Option Exercise | 43,170 |
| BMRN | Chief Executive Officer | Jan 22, 2019 | Sale | 290,460 |
| BMRN | Chief Executive Officer | Jan 14, 2019 | Option Exercise | 57,560 |
| BMRN | Chief Executive Officer | Jan 14, 2019 | Sale | 375,160 |
| BMRN | Chief Executive Officer | Jan 10, 2019 | Option Exercise | 43,170 |
| BMRN | Chief Executive Officer | Jan 10, 2019 | Sale | 271,650 |
| BMRN | Chief Executive Officer | Jan 08, 2019 | Option Exercise | 86,340 |
| BMRN | Chief Executive Officer | Jan 08, 2019 | Sale | 549,523 |
| BMRN | Chief Executive Officer | Jan 07, 2019 | Option Exercise | 43,170 |
| BMRN | Chief Executive Officer | Jan 07, 2019 | Sale | 262,740 |
| INCY | Director | Dec 31, 2018 | Option Exercise | 14,499 |
| BMRN | Chief Executive Officer | Dec 28, 2018 | Option Exercise | 43,170 |
| BMRN | Chief Executive Officer | Dec 28, 2018 | Sale | 252,120 |
| BMRN | Chief Executive Officer | Dec 26, 2018 | Option Exercise | 57,560 |
| BMRN | Chief Executive Officer | Dec 26, 2018 | Sale | 322,000 |
| BMRN | Chief Executive Officer | Dec 14, 2018 | Option Exercise | 35,720 |
| BMRN | Chief Executive Officer | Dec 14, 2018 | Sale | 185,280 |
| BMRN | Chief Executive Officer | Dec 12, 2018 | Option Exercise | 35,720 |
| BMRN | Chief Executive Officer | Dec 12, 2018 | Sale | 186,240 |
| INCY | Director | Nov 08, 2018 | Buy | 68,765 |
| BMRN | Chief Executive Officer | Nov 02, 2018 | Option Exercise | 26,790 |
| BMRN | Chief Executive Officer | Nov 02, 2018 | Sale | 146,820 |
| BMRN | Chief Executive Officer | Nov 01, 2018 | Option Exercise | 57,560 |
| BMRN | Chief Executive Officer | Nov 01, 2018 | Sale | 370,200 |
| BMRN | Chief Executive Officer | Oct 30, 2018 | Option Exercise | 14,390 |
| BMRN | Chief Executive Officer | Oct 24, 2018 | Option Exercise | 14,390 |
| BMRN | Chief Executive Officer | Oct 03, 2018 | Option Exercise | 26,790 |
| BMRN | Chief Executive Officer | Oct 03, 2018 | Sale | 149,040 |
| INCY | Director | Sep 28, 2018 | Option Exercise | 14,438 |
| BMRN | Chief Executive Officer | Sep 25, 2018 | Option Exercise | 14,390 |
| VTL | Director | Sep 24, 2018 | Sale | 8,002 |
| VTL | Director | Sep 13, 2018 | Sale | 9,400 |
| BMRN | Chief Executive Officer | Sep 04, 2018 | Option Exercise | 26,790 |
| BMRN | Chief Executive Officer | Sep 04, 2018 | Sale | 147,240 |
| BMRN | Chief Executive Officer | Jul 23, 2018 | Option Exercise | 26,790 |
| BMRN | Chief Executive Officer | Jul 23, 2018 | Sale | 152,535 |
| INCY | Director | Jun 29, 2018 | Option Exercise | 14,472 |
| BMRN | Chief Executive Officer | Jun 13, 2018 | Option Exercise | 14,390 |
| BMRN | Chief Executive Officer | Jun 04, 2018 | Option Exercise | 580,962 |
| BMRN | Chief Executive Officer | May 17, 2018 | Option Exercise | 723,563 |
| BMRN | Chief Executive Officer | May 17, 2018 | Sale | 1,662,356 |
| BMRN | Chief Executive Officer | May 16, 2018 | Option Exercise | 723,563 |
| BMRN | Chief Executive Officer | May 16, 2018 | Sale | 1,671,131 |
| BMRN | Chief Executive Officer | May 15, 2018 | Option Exercise | 723,563 |
| BMRN | Chief Executive Officer | May 14, 2018 | Option Exercise | 723,563 |
| BMRN | Chief Executive Officer | May 15, 2018 | Sale | 1,655,434 |
| BMRN | Chief Executive Officer | May 14, 2018 | Sale | 1,672,851 |
| BMRN | Chief Executive Officer | Apr 30, 2018 | Option Exercise | 21,254 |
| BMRN | Chief Executive Officer | May 11, 2018 | Option Exercise | 723,563 |
| BMRN | Chief Executive Officer | May 10, 2018 | Option Exercise | 723,563 |
| BMRN | Chief Executive Officer | May 11, 2018 | Sale | 1,657,856 |
| BMRN | Chief Executive Officer | May 10, 2018 | Sale | 1,679,794 |
| BMRN | Chief Executive Officer | Mar 22, 2018 | Option Exercise | 1,068,013 |
| BMRN | Chief Executive Officer | Apr 24, 2018 | Option Exercise | 385,900 |
| BMRN | Chief Executive Officer | Apr 23, 2018 | Option Exercise | 385,900 |
| BMRN | Chief Executive Officer | Apr 23, 2018 | Sale | 825,811 |
| BMRN | Chief Executive Officer | Apr 24, 2018 | Sale | 822,887 |
| BMRN | Chief Executive Officer | Apr 20, 2018 | Option Exercise | 385,900 |
| BMRN | Chief Executive Officer | Apr 20, 2018 | Sale | 836,458 |
| BMRN | Chief Executive Officer | Apr 05, 2018 | Option Exercise | 14,390 |
| BMRN | Chief Executive Officer | Apr 02, 2018 | Option Exercise | 14,390 |
| INCY | Director | Mar 29, 2018 | Option Exercise | 14,499 |
| BMRN | Chief Executive Officer | Mar 28, 2018 | Option Exercise | 32,250 |
| BMRN | Chief Executive Officer | Mar 27, 2018 | Option Exercise | 14,390 |
| BMRN | Chief Executive Officer | Mar 26, 2018 | Option Exercise | 14,390 |
| BMRN | Chief Executive Officer | Mar 22, 2018 | Option Exercise | 1,063,782 |
| BMRN | Chief Executive Officer | Mar 22, 2018 | Option Exercise | 14,390 |
| BMRN | Chief Executive Officer | Mar 16, 2018 | Option Exercise | 578,850 |
| BMRN | Chief Executive Officer | Mar 16, 2018 | Sale | 1,248,853 |
| BMRN | Chief Executive Officer | Mar 15, 2018 | Option Exercise | 1,245,862 |
| BMRN | Chief Executive Officer | Mar 15, 2018 | Option Exercise | 578,850 |
| BMRN | Chief Executive Officer | Mar 15, 2018 | Sale | 1,270,900 |
| BMRN | Chief Executive Officer | Mar 02, 2018 | Option Exercise | 682,164 |
| BMRN | Chief Executive Officer | Mar 02, 2018 | Option Exercise | 14,390 |
| BMRN | Chief Executive Officer | Feb 15, 2018 | Option Exercise | 385,900 |
| BMRN | Chief Executive Officer | Feb 15, 2018 | Sale | 846,285 |
| BMRN | Chief Executive Officer | Jan 05, 2018 | Option Exercise | 385,900 |
| BMRN | Chief Executive Officer | Jan 05, 2018 | Sale | 903,203 |
| INCY | Director | Dec 29, 2017 | Option Exercise | 14,491 |
| BMRN | Chief Executive Officer | Dec 29, 2017 | Option Exercise | 385,900 |
| BMRN | Chief Executive Officer | Dec 28, 2017 | Option Exercise | 385,900 |
| BMRN | Chief Executive Officer | Dec 29, 2017 | Sale | 896,125 |
| BMRN | Chief Executive Officer | Dec 28, 2017 | Sale | 898,912 |
| INCY | Director | Sep 29, 2017 | Option Exercise | 14,476 |
| VTL | Director | Sep 13, 2017 | Buy | 39,969 |
| INCY | Director | Jun 30, 2017 | Option Exercise | 14,480 |
| VTL | Director | Jun 13, 2017 | Buy | 48,069 |
| BMRN | Chief Executive Officer | Jun 02, 2017 | Option Exercise | 602,381 |
| BMRN | Chief Executive Officer | Jun 05, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | Jun 02, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | Jun 05, 2017 | Sale | 452,800 |
| BMRN | Chief Executive Officer | Jun 02, 2017 | Sale | 448,500 |
| BMRN | Chief Executive Officer | Jun 01, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | Jun 01, 2017 | Sale | 437,650 |
| BMRN | Chief Executive Officer | May 31, 2017 | Option Exercise | 128,641 |
| BMRN | Chief Executive Officer | May 31, 2017 | Sale | 655,377 |
| INCY | Director | May 31, 2017 | Buy | 65,900 |
| BMRN | Chief Executive Officer | May 24, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | May 24, 2017 | Sale | 441,900 |
| BMRN | Chief Executive Officer | May 17, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | May 17, 2017 | Sale | 458,650 |
| BMRN | Chief Executive Officer | May 15, 2017 | Option Exercise | 451,278 |
| INCY | Director | May 15, 2017 | Buy | 57,500 |
| BMRN | Chief Executive Officer | May 12, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | May 12, 2017 | Sale | 446,150 |
| BMRN | Chief Executive Officer | Apr 28, 2017 | Option Exercise | 21,232 |
| BMRN | Chief Executive Officer | May 08, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | May 05, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | May 05, 2017 | Sale | 495,000 |
| BMRN | Chief Executive Officer | May 08, 2017 | Sale | 465,850 |
| INCY | Director | Apr 28, 2017 | Buy | 62,130 |
| BMRN | Chief Executive Officer | Apr 27, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | Apr 27, 2017 | Sale | 478,600 |
| BMRN | Chief Executive Officer | Apr 25, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | Apr 25, 2017 | Sale | 470,000 |
| INCY | Director | Apr 13, 2017 | Buy | 139,660 |
| INCY | Director | Apr 07, 2017 | Buy | 139,480 |
| BMRN | Chief Executive Officer | Apr 04, 2017 | Option Exercise | 43,170 |
| INCY | Director | Mar 31, 2017 | Option Exercise | 14,436 |
| BMRN | Chief Executive Officer | Mar 15, 2017 | Option Exercise | 1,451,325 |
| BMRN | Chief Executive Officer | Mar 16, 2017 | Option Exercise | 356,650 |
| BMRN | Chief Executive Officer | Mar 15, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | Mar 16, 2017 | Sale | 459,800 |
| BMRN | Chief Executive Officer | Mar 15, 2017 | Sale | 457,100 |
| BMRN | Chief Executive Officer | Mar 13, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | Mar 13, 2017 | Sale | 463,400 |
| BMRN | Chief Executive Officer | Mar 10, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | Mar 09, 2017 | Option Exercise | 103,980 |
| BMRN | Chief Executive Officer | Mar 10, 2017 | Sale | 455,450 |
| BMRN | Chief Executive Officer | Mar 09, 2017 | Sale | 541,080 |
| BMRN | Chief Executive Officer | Mar 03, 2017 | Option Exercise | 844,517 |
| BMRN | Chief Executive Officer | Jan 26, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | Jan 25, 2017 | Option Exercise | 86,650 |
| BMRN | Chief Executive Officer | Jan 26, 2017 | Sale | 420,000 |
| BMRN | Chief Executive Officer | Jan 25, 2017 | Sale | 422,200 |
| BMRN | Chief Executive Officer | Jan 10, 2017 | Option Exercise | 69,320 |
| BMRN | Chief Executive Officer | Jan 11, 2017 | Option Exercise | 69,320 |
| BMRN | Chief Executive Officer | Jan 11, 2017 | Sale | 359,360 |
| BMRN | Chief Executive Officer | Jan 10, 2017 | Sale | 365,240 |
| BMRN | Chief Executive Officer | Jan 09, 2017 | Option Exercise | 69,320 |
| BMRN | Chief Executive Officer | Jan 06, 2017 | Option Exercise | 69,320 |
| BMRN | Chief Executive Officer | Jan 09, 2017 | Sale | 359,160 |
| BMRN | Chief Executive Officer | Jan 06, 2017 | Sale | 348,760 |
| BMRN | Chief Executive Officer | Dec 30, 2016 | Option Exercise | 69,320 |
| BMRN | Chief Executive Officer | Dec 29, 2016 | Option Exercise | 69,320 |
| BMRN | Chief Executive Officer | Dec 29, 2016 | Sale | 335,360 |
| BMRN | Chief Executive Officer | Dec 30, 2016 | Sale | 333,400 |
| INCY | Director | Dec 30, 2016 | Option Exercise | 14,439 |
| BMRN | Chief Executive Officer | Nov 21, 2016 | Option Exercise | 1,847,519 |
| BMRN | Chief Executive Officer | Nov 22, 2016 | Option Exercise | 1,847,492 |
| BMRN | Chief Executive Officer | Nov 22, 2016 | Sale | 5,976,515 |
| BMRN | Chief Executive Officer | Nov 21, 2016 | Sale | 6,106,478 |
| BMRN | Chief Executive Officer | Nov 16, 2016 | Option Exercise | 730,892 |
| BMRN | Chief Executive Officer | Nov 16, 2016 | Sale | 3,790,795 |
| BMRN | Chief Executive Officer | Nov 08, 2016 | Option Exercise | 1,505,700 |
| BMRN | Chief Executive Officer | Nov 07, 2016 | Option Exercise | 1,505,700 |
| BMRN | Chief Executive Officer | Nov 08, 2016 | Sale | 5,797,806 |
| BMRN | Chief Executive Officer | Nov 07, 2016 | Sale | 5,776,435 |
| BMRN | Chief Executive Officer | Oct 28, 2016 | Option Exercise | 863,400 |
| BMRN | Chief Executive Officer | Oct 27, 2016 | Option Exercise | 863,400 |
| BMRN | Chief Executive Officer | Oct 28, 2016 | Sale | 4,875,990 |
| BMRN | Chief Executive Officer | Oct 27, 2016 | Sale | 4,880,448 |
| BMRN | Chief Executive Officer | Oct 17, 2016 | Option Exercise | 730,822 |
| BMRN | Chief Executive Officer | Oct 17, 2016 | Sale | 3,516,227 |
| BMRN | Chief Executive Officer | Oct 14, 2016 | Option Exercise | 196,460 |
| BMRN | Chief Executive Officer | Oct 13, 2016 | Option Exercise | 2,050,094 |
| BMRN | Chief Executive Officer | Oct 14, 2016 | Sale | 955,814 |
| BMRN | Chief Executive Officer | Oct 13, 2016 | Sale | 4,620,563 |
| INCY | Director | Sep 30, 2016 | Option Exercise | 14,426 |
| BMRN | Chief Executive Officer | Sep 30, 2016 | Option Exercise | 2,050,094 |
| BMRN | Chief Executive Officer | Sep 30, 2016 | Sale | 4,888,780 |
| BMRN | Chief Executive Officer | Sep 29, 2016 | Option Exercise | 2,050,094 |
| BMRN | Chief Executive Officer | Sep 29, 2016 | Sale | 4,974,901 |
| BMRN | Chief Executive Officer | Sep 16, 2016 | Option Exercise | 2,780,915 |
| BMRN | Chief Executive Officer | Sep 15, 2016 | Option Exercise | 737,859 |
| BMRN | Chief Executive Officer | Sep 16, 2016 | Sale | 9,058,601 |
| BMRN | Chief Executive Officer | Sep 15, 2016 | Sale | 4,038,360 |
| BMRN | Chief Executive Officer | Aug 16, 2016 | Option Exercise | 730,822 |
| BMRN | Chief Executive Officer | Aug 16, 2016 | Sale | 3,811,868 |
| BMRN | Chief Executive Officer | Jul 18, 2016 | Option Exercise | 730,822 |
| BMRN | Chief Executive Officer | Jul 18, 2016 | Sale | 3,863,272 |
| INCY | Director | Jun 30, 2016 | Option Exercise | 14,476 |
| BMRN | Chief Executive Officer | Jun 16, 2016 | Option Exercise | 730,822 |
| BMRN | Chief Executive Officer | Jun 16, 2016 | Sale | 3,356,196 |
| BMRN | Chief Executive Officer | Jun 03, 2016 | Option Exercise | 597,600 |
| BMRN | Chief Executive Officer | May 13, 2016 | Option Exercise | 407,926 |
| BMRN | Chief Executive Officer | May 06, 2016 | Option Exercise | 442,703 |
| BMRN | Chief Executive Officer | May 05, 2016 | Option Exercise | 129,900 |
| BMRN | Chief Executive Officer | May 05, 2016 | Option Exercise | 931,389 |
| BMRN | Chief Executive Officer | May 05, 2016 | Option Exercise | 129,900 |
| BMRN | Chief Executive Officer | May 05, 2016 | Option Exercise | 259,800 |
| BMRN | Chief Executive Officer | May 05, 2016 | Option Exercise | 129,900 |
| BMRN | Chief Executive Officer | May 05, 2016 | Sale | 801,489 |
| BMRN | Chief Executive Officer | May 05, 2016 | Sale | 1,602,978 |
| BMRN | Chief Executive Officer | May 05, 2016 | Sale | 801,489 |
| BMRN | Chief Executive Officer | May 05, 2016 | Sale | 801,489 |
| BMRN | Chief Executive Officer | Apr 29, 2016 | Option Exercise | 21,223 |
| BMRN | Chief Executive Officer | May 02, 2016 | Option Exercise | 474,135 |
| BMRN | Chief Executive Officer | May 02, 2016 | Sale | 3,102,931 |
| BMRN | Chief Executive Officer | Apr 06, 2016 | Option Exercise | 21,585 |
| BMRN | Chief Executive Officer | Apr 05, 2016 | Option Exercise | 21,585 |
| INCY | Director | Mar 31, 2016 | Option Exercise | 14,494 |
| BMRN | Chief Executive Officer | Mar 03, 2016 | Option Exercise | 805,145 |
| BMRN | Chief Executive Officer | Feb 29, 2016 | Option Exercise | 15,799,437 |
| BMRN | Chief Executive Officer | Mar 01, 2016 | Sale | 842,769 |
| INCY | Director | Dec 31, 2015 | Option Exercise | 14,424 |
| BMRN | Chief Executive Officer | Nov 30, 2015 | Sale | 94,744 |
| BMRN | Chief Executive Officer | Oct 15, 2015 | Sale | 108,241 |
| INCY | Director | Oct 01, 2015 | Option Exercise | 14,453 |
| BMRN | Chief Executive Officer | Sep 14, 2015 | Sale | 131,432 |
| VTL | Director | Sep 10, 2015 | Buy | 18,293 |
| VTL | Director | Sep 09, 2015 | Buy | 24,800 |
| BMRN | Chief Executive Officer | Aug 12, 2015 | Sale | 202,083 |
| BMRN | Chief Executive Officer | Jul 07, 2015 | Sale | 208,599 |
| INCY | Director | Jul 01, 2015 | Option Exercise | 13,235 |
| BMRN | Chief Executive Officer | Jun 04, 2015 | Option Exercise | 799,854 |
| BMRN | Chief Executive Officer | May 21, 2015 | Sale | 189,158 |
| BMRN | Chief Executive Officer | May 15, 2015 | Option Exercise | 605,551 |
| BMRN | Chief Executive Officer | May 12, 2015 | Option Exercise | 284,440 |
| BMRN | Chief Executive Officer | May 08, 2015 | Option Exercise | 666,575 |
| BMRN | Chief Executive Officer | Apr 30, 2015 | Option Exercise | 46,547 |
| BMRN | Chief Executive Officer | May 01, 2015 | Option Exercise | 149,988 |
| BMRN | Chief Executive Officer | May 01, 2015 | Sale | 402,991 |
| BMRN | Chief Executive Officer | May 01, 2015 | Sale | 2,669,513 |
| BMRN | Chief Executive Officer | Apr 01, 2015 | Option Exercise | 145,647 |
| BMRN | Chief Executive Officer | Apr 01, 2015 | Sale | 2,717,537 |
| BMRN | Chief Executive Officer | Apr 01, 2015 | Sale | 422,589 |
| BMRN | Chief Executive Officer | Mar 20, 2015 | Sale | 126,396 |
| BMRN | Chief Executive Officer | Mar 17, 2015 | Sale | 124,866 |
| BMRN | Chief Executive Officer | Mar 16, 2015 | Sale | 123,477 |
| BMRN | Chief Executive Officer | Mar 09, 2015 | Option Exercise | 194,850 |
| BMRN | Chief Executive Officer | Mar 10, 2015 | Sale | 232,201 |
| BMRN | Chief Executive Officer | Mar 09, 2015 | Sale | 2,130,391 |
| BMRN | Chief Executive Officer | Mar 05, 2015 | Option Exercise | 129,900 |
| BMRN | Chief Executive Officer | Mar 05, 2015 | Sale | 1,137,020 |
| BMRN | Chief Executive Officer | Mar 04, 2015 | Option Exercise | 4,930 |
| BMRN | Chief Executive Officer | Mar 02, 2015 | Option Exercise | 38,970 |
| BMRN | Chief Executive Officer | Mar 03, 2015 | Sale | 537,095 |
| BMRN | Chief Executive Officer | Mar 02, 2015 | Sale | 542,195 |
| BMRN | Chief Executive Officer | Mar 02, 2015 | Sale | 323,892 |
| BMRN | Chief Executive Officer | Mar 04, 2015 | Sale | 98,661 |
| BMRN | Chief Executive Officer | Jan 09, 2015 | Sale | 188,286 |
| BMRN | Chief Executive Officer | Dec 24, 2014 | Option Exercise | 38,970 |
| BMRN | Chief Executive Officer | Dec 24, 2014 | Sale | 177,462 |
| BMRN | Chief Executive Officer | Dec 24, 2014 | Sale | 266,193 |
| BMRN | Chief Executive Officer | Dec 10, 2014 | Option Exercise | 25,980 |
| BMRN | Chief Executive Officer | Dec 10, 2014 | Sale | 190,000 |
| BMRN | Chief Executive Officer | Nov 25, 2014 | Option Exercise | 25,980 |
| BMRN | Chief Executive Officer | Nov 25, 2014 | Sale | 180,000 |
| BMRN | Chief Executive Officer | Nov 12, 2014 | Sale | 85,513 |
| BMRN | Chief Executive Officer | Nov 12, 2014 | Sale | 81,513 |
| BMRN | Chief Executive Officer | Nov 10, 2014 | Option Exercise | 51,960 |
| BMRN | Chief Executive Officer | Nov 10, 2014 | Sale | 348,000 |
| BMRN | Chief Executive Officer | Nov 03, 2014 | Sale | 256,002 |
| BMRN | Chief Executive Officer | Oct 24, 2014 | Option Exercise | 25,980 |
| BMRN | Chief Executive Officer | Oct 24, 2014 | Sale | 160,000 |
| BMRN | Chief Executive Officer | Oct 21, 2014 | Option Exercise | 25,980 |
| BMRN | Chief Executive Officer | Oct 21, 2014 | Sale | 150,000 |
| VTL | Director | Oct 08, 2014 | Buy | 75,005 |
| ITMN | Director | Sep 29, 2014 | Option Exercise | 88,800 |
| ITMN | Director | Sep 29, 2014 | Option Exercise | 630,850 |
| BMRN | Chief Executive Officer | Aug 20, 2014 | Option Exercise | 64,950 |
| BMRN | Chief Executive Officer | Aug 20, 2014 | Sale | 350,000 |
| BMRN | Chief Executive Officer | Jun 04, 2014 | Sale | 62,521 |
| BMRN | Chief Executive Officer | Jun 03, 2014 | Sale | 59,876 |
| BMRN | Chief Executive Officer | May 22, 2014 | Sale | 56,876 |
| BMRN | Chief Executive Officer | May 21, 2014 | Sale | 86,817 |
| BMRN | Chief Executive Officer | May 15, 2014 | Option Exercise | 283,294 |
| PTLA | Director | May 16, 2014 | Sale | 22,030 |
| BMRN | Chief Executive Officer | May 12, 2014 | Option Exercise | 270,823 |
| BMRN | Chief Executive Officer | Apr 30, 2014 | Option Exercise | 21,228 |
| BMRN | Chief Executive Officer | May 08, 2014 | Option Exercise | 311,098 |
| VTL | Director | Apr 23, 2001 | Buy | 99,996 |
| BMRN | Chief Executive Officer | Mar 28, 2014 | Option Exercise | 25,980 |
| PTLA | Director | Mar 06, 2014 | Sale | 25,150 |
| PTLA | Director | May 22, 2013 | Buy | 29,000 |
| BMRN | Chief Executive Officer | Feb 20, 2014 | Sale | 640,000 |
| BMRN | Chief Executive Officer | Feb 06, 2014 | Option Exercise | 51,960 |
| BMRN | Chief Executive Officer | Jan 10, 2014 | Option Exercise | 64,950 |
| BMRN | Chief Executive Officer | Jan 10, 2014 | Sale | 350,000 |
| BMRN | Chief Executive Officer | Jan 06, 2014 | Option Exercise | 129,900 |
| BMRN | Chief Executive Officer | Jan 06, 2014 | Sale | 674,096 |
| BMRN | Chief Executive Officer | Jan 02, 2014 | Option Exercise | 64,950 |
| BMRN | Chief Executive Officer | Jan 02, 2014 | Sale | 344,482 |
| BMRN | Chief Executive Officer | Dec 24, 2013 | Option Exercise | 129,900 |
| BMRN | Chief Executive Officer | Dec 24, 2013 | Sale | 687,143 |
| BMRN | Chief Executive Officer | Dec 05, 2013 | Option Exercise | 64,950 |
| BMRN | Chief Executive Officer | Dec 05, 2013 | Sale | 348,484 |
| BMRN | Chief Executive Officer | Nov 14, 2013 | Option Exercise | 64,950 |
| BMRN | Chief Executive Officer | Nov 05, 2013 | Option Exercise | 64,950 |
| BMRN | Chief Executive Officer | Nov 05, 2013 | Sale | 311,779 |
| BMRN | Chief Executive Officer | Oct 31, 2013 | Option Exercise | 129,900 |
| BMRN | Chief Executive Officer | Oct 31, 2013 | Sale | 627,155 |
| BMRN | Chief Executive Officer | Oct 16, 2013 | Option Exercise | 25,980 |
| BMRN | Chief Executive Officer | Oct 16, 2013 | Sale | 135,450 |
| BMRN | Chief Executive Officer | Oct 10, 2013 | Sale | 200,291 |
| BMRN | Chief Executive Officer | Sep 16, 2013 | Option Exercise | 25,980 |
| BMRN | Chief Executive Officer | Sep 16, 2013 | Sale | 146,163 |
| BMRN | Chief Executive Officer | Aug 15, 2013 | Option Exercise | 12,990 |
| BMRN | Chief Executive Officer | Aug 15, 2013 | Sale | 64,364 |
| BMRN | Chief Executive Officer | Jul 15, 2013 | Option Exercise | 76,688 |
| BMRN | Chief Executive Officer | Jun 12, 2013 | Option Exercise | 64,950 |
| BMRN | Chief Executive Officer | Jun 05, 2013 | Option Exercise | 723,306 |
| BMRN | Chief Executive Officer | Jun 04, 2013 | Option Exercise | 737,094 |
| BMRN | Chief Executive Officer | May 31, 2013 | Option Exercise | 38,970 |
| BMRN | Chief Executive Officer | May 21, 2013 | Option Exercise | 25,980 |
| BMRN | Chief Executive Officer | May 21, 2013 | Sale | 128,279 |
| BMRN | Chief Executive Officer | May 12, 2013 | Option Exercise | 591,659 |
| BMRN | Chief Executive Officer | May 13, 2013 | Option Exercise | 103,920 |
| BMRN | Chief Executive Officer | May 10, 2013 | Sale | 53,985 |
| BMRN | Chief Executive Officer | May 13, 2013 | Sale | 552,896 |
| BMRN | Chief Executive Officer | May 13, 2013 | Sale | 479,720 |
| BMRN | Chief Executive Officer | May 16, 2013 | Option Exercise | 349,248 |
| BMRN | Chief Executive Officer | May 15, 2013 | Option Exercise | 129,900 |
| BMRN | Chief Executive Officer | May 17, 2013 | Option Exercise | 320,050 |
| BMRN | Chief Executive Officer | May 16, 2013 | Sale | 129,307 |
| BMRN | Chief Executive Officer | May 15, 2013 | Sale | 685,477 |
| BMRN | Chief Executive Officer | May 14, 2013 | Option Exercise | 194,850 |
| BMRN | Chief Executive Officer | May 14, 2013 | Sale | 1,052,491 |
| BMRN | Chief Executive Officer | May 14, 2013 | Option Exercise | 324,750 |
| BMRN | Chief Executive Officer | May 14, 2013 | Sale | 1,773,551 |
| BMRN | Chief Executive Officer | May 12, 2013 | Option Exercise | 600,525 |
| BMRN | Chief Executive Officer | May 13, 2013 | Option Exercise | 103,920 |
| BMRN | Chief Executive Officer | May 13, 2013 | Sale | 552,896 |
| BMRN | Chief Executive Officer | May 13, 2013 | Sale | 479,720 |
| BMRN | Chief Executive Officer | May 10, 2013 | Sale | 53,985 |
| BMRN | Chief Executive Officer | May 08, 2013 | Option Exercise | 357,888 |
| BMRN | Chief Executive Officer | May 07, 2013 | Option Exercise | 38,970 |
| BMRN | Chief Executive Officer | May 08, 2013 | Sale | 65,879 |
| BMRN | Chief Executive Officer | May 07, 2013 | Sale | 197,613 |
| BMRN | Chief Executive Officer | May 03, 2013 | Option Exercise | 103,920 |
| BMRN | Chief Executive Officer | May 03, 2013 | Sale | 537,950 |
| BMRN | Chief Executive Officer | Apr 30, 2013 | Option Exercise | 21,256 |
| BMRN | Chief Executive Officer | May 02, 2013 | Option Exercise | 25,980 |
| BMRN | Chief Executive Officer | Apr 30, 2013 | Sale | 63,742 |
| BMRN | Chief Executive Officer | May 02, 2013 | Sale | 131,241 |
| BMRN | Chief Executive Officer | Mar 26, 2013 | Option Exercise | 155,880 |
| BMRN | Chief Executive Officer | Mar 26, 2013 | Sale | 728,147 |
| BMRN | Chief Executive Officer | Mar 04, 2013 | Option Exercise | 64,950 |
| BMRN | Chief Executive Officer | Feb 28, 2013 | Option Exercise | 64,950 |
| BMRN | Chief Executive Officer | Feb 28, 2013 | Sale | 290,000 |
| BMRN | Chief Executive Officer | Mar 01, 2013 | Sale | 59,140 |
| BMRN | Chief Executive Officer | Mar 04, 2013 | Sale | 300,000 |
| BMRN | Chief Executive Officer | Feb 27, 2013 | Sale | 84,683 |
| BMRN | Chief Executive Officer | Feb 04, 2013 | Option Exercise | 25,980 |
| BMRN | Chief Executive Officer | Feb 04, 2013 | Sale | 111,532 |
| BMRN | Chief Executive Officer | Jan 23, 2013 | Sale | 220,880 |
| BMRN | Chief Executive Officer | Jan 22, 2013 | Sale | 550,000 |
| BMRN | Chief Executive Officer | Jan 18, 2013 | Option Exercise | 64,950 |
| BMRN | Chief Executive Officer | Jan 18, 2013 | Sale | 270,000 |
| BMRN | Chief Executive Officer | Jan 04, 2013 | Option Exercise | 38,970 |
| BMRN | Chief Executive Officer | Jan 04, 2013 | Sale | 156,731 |
| BMRN | Chief Executive Officer | Dec 31, 2012 | Option Exercise | 64,950 |
| BMRN | Chief Executive Officer | Dec 31, 2012 | Sale | 243,116 |
| BMRN | Chief Executive Officer | Dec 27, 2012 | Option Exercise | 51,960 |
| BMRN | Chief Executive Officer | Dec 26, 2012 | Option Exercise | 90,930 |
| BMRN | Chief Executive Officer | Dec 24, 2012 | Option Exercise | 77,940 |
| BMRN | Chief Executive Officer | Dec 26, 2012 | Sale | 338,633 |
| BMRN | Chief Executive Officer | Dec 24, 2012 | Sale | 290,252 |
| BMRN | Chief Executive Officer | Dec 27, 2012 | Sale | 193,360 |
| BMRN | Chief Executive Officer | Dec 21, 2012 | Option Exercise | 116,910 |
| BMRN | Chief Executive Officer | Dec 21, 2012 | Sale | 437,137 |
| BMRN | Chief Executive Officer | Dec 12, 2012 | Option Exercise | 64,950 |
| BMRN | Chief Executive Officer | Dec 12, 2012 | Sale | 250,000 |
| BMRN | Chief Executive Officer | Dec 07, 2012 | Option Exercise | 29,580 |
| BMRN | Chief Executive Officer | Dec 10, 2012 | Option Exercise | 38,970 |
| BMRN | Chief Executive Officer | Dec 10, 2012 | Sale | 144,084 |
| BMRN | Chief Executive Officer | Dec 07, 2012 | Sale | 141,123 |
| BMRN | Chief Executive Officer | Dec 04, 2012 | Option Exercise | 64,950 |
| BMRN | Chief Executive Officer | Dec 04, 2012 | Sale | 239,692 |
| BMRN | Chief Executive Officer | Nov 16, 2012 | Option Exercise | 103,920 |
| BMRN | Chief Executive Officer | Nov 16, 2012 | Sale | 384,366 |
| BMRN | Chief Executive Officer | Nov 09, 2012 | Sale | 96,844 |
| BMRN | Chief Executive Officer | Nov 07, 2012 | Sale | 236,470 |
| BMRN | Chief Executive Officer | Oct 31, 2012 | Option Exercise | 29,580 |
| BMRN | Chief Executive Officer | Oct 31, 2012 | Sale | 151,856 |
| BMRN | Chief Executive Officer | Oct 22, 2012 | Option Exercise | 29,580 |
| BMRN | Chief Executive Officer | Oct 22, 2012 | Sale | 125,579 |
| BMRN | Chief Executive Officer | Oct 19, 2012 | Sale | 85,440 |
| BMRN | Chief Executive Officer | Oct 12, 2012 | Option Exercise | 29,580 |
| BMRN | Chief Executive Officer | Oct 12, 2012 | Sale | 123,969 |
| BMRN | Chief Executive Officer | Sep 28, 2012 | Option Exercise | 39,440 |
| BMRN | Chief Executive Officer | Sep 28, 2012 | Sale | 160,804 |
| BMRN | Chief Executive Officer | Sep 14, 2012 | Option Exercise | 39,440 |
| BMRN | Chief Executive Officer | Sep 14, 2012 | Sale | 151,628 |
| BMRN | Chief Executive Officer | Sep 10, 2012 | Sale | 38,620 |
| ITMN | Director | Jun 04, 2012 | Option Exercise | 25,250 |
| BMRN | Chief Executive Officer | May 31, 2012 | Option Exercise | 12,920 |
| BMRN | Chief Executive Officer | May 31, 2012 | Option Exercise | 51,680 |
| BMRN | Chief Executive Officer | May 16, 2012 | Option Exercise | 147,900 |
| BMRN | Chief Executive Officer | May 16, 2012 | Sale | 577,369 |
| BMRN | Chief Executive Officer | May 11, 2012 | Option Exercise | 212,500 |
| BMRN | Chief Executive Officer | May 14, 2012 | Option Exercise | 147,900 |
| BMRN | Chief Executive Officer | May 14, 2012 | Sale | 571,893 |
| BMRN | Chief Executive Officer | May 11, 2012 | Sale | 969,656 |
| BMRN | Chief Executive Officer | May 08, 2012 | Option Exercise | 147,900 |
| BMRN | Chief Executive Officer | May 07, 2012 | Option Exercise | 49,300 |
| BMRN | Chief Executive Officer | May 08, 2012 | Sale | 547,800 |
| BMRN | Chief Executive Officer | May 07, 2012 | Sale | 179,800 |
| BMRN | Chief Executive Officer | May 03, 2012 | Option Exercise | 98,600 |
| BMRN | Chief Executive Officer | May 04, 2012 | Option Exercise | 98,600 |
| BMRN | Chief Executive Officer | May 03, 2012 | Sale | 366,800 |
| BMRN | Chief Executive Officer | May 04, 2012 | Sale | 360,000 |
| BMRN | Chief Executive Officer | Apr 30, 2012 | Option Exercise | 21,242 |
| BMRN | Chief Executive Officer | May 02, 2012 | Option Exercise | 98,600 |
| BMRN | Chief Executive Officer | May 01, 2012 | Option Exercise | 197,200 |
| BMRN | Chief Executive Officer | May 02, 2012 | Sale | 357,200 |
| BMRN | Chief Executive Officer | May 01, 2012 | Sale | 699,920 |
| BMRN | Chief Executive Officer | Apr 27, 2012 | Option Exercise | 197,200 |
| BMRN | Chief Executive Officer | Apr 27, 2012 | Sale | 769,872 |
| BMRN | Chief Executive Officer | Mar 09, 2012 | Option Exercise | 97,050 |
| BMRN | Chief Executive Officer | Mar 09, 2012 | Sale | 516,867 |
| BMRN | Chief Executive Officer | Mar 08, 2012 | Sale | 35,000 |
| BMRN | Chief Executive Officer | Feb 29, 2012 | Sale | 36,258 |
| BMRN | Chief Executive Officer | Feb 27, 2012 | Sale | 107,813 |
| BMRN | Chief Executive Officer | Feb 24, 2012 | Sale | 70,396 |
| BMRN | Chief Executive Officer | Feb 23, 2012 | Sale | 176,541 |
| BMRN | Chief Executive Officer | Sep 28, 2011 | Sale | 32,000 |
| BMRN | Chief Executive Officer | Aug 30, 2011 | Option Exercise | 12,920 |
| BMRN | Chief Executive Officer | Aug 30, 2011 | Sale | 58,018 |
| BMRN | Chief Executive Officer | Aug 19, 2011 | Option Exercise | 12,920 |
| BMRN | Chief Executive Officer | Aug 19, 2011 | Sale | 53,496 |
| BMRN | Chief Executive Officer | Aug 12, 2011 | Option Exercise | 19,380 |
| BMRN | Chief Executive Officer | Aug 12, 2011 | Sale | 81,288 |
| BMRN | Chief Executive Officer | Aug 02, 2011 | Option Exercise | 25,840 |
| BMRN | Chief Executive Officer | Aug 02, 2011 | Sale | 242,136 |
| NGSX | Director | Jul 26, 2011 | Option Exercise | 19,185 |
| BMRN | Chief Executive Officer | Jul 14, 2011 | Sale | 30,000 |
| BMRN | Chief Executive Officer | Jun 06, 2011 | Sale | 54,772 |
| BMRN | Chief Executive Officer | May 31, 2011 | Sale | 19,880 |
| BMRN | Chief Executive Officer | May 27, 2011 | Sale | 8,120 |
| BMRN | Chief Executive Officer | May 25, 2011 | Sale | 26,944 |
| BMRN | Chief Executive Officer | May 25, 2011 | Sale | 26,944 |
| BMRN | Chief Executive Officer | May 10, 2011 | Sale | 10,346 |
| BMRN | Chief Executive Officer | May 05, 2011 | Sale | 5,128 |
| BMRN | Chief Executive Officer | Apr 29, 2011 | Option Exercise | 21,249 |
| BMRN | Chief Executive Officer | May 04, 2011 | Option Exercise | 9,860 |
| BMRN | Chief Executive Officer | May 03, 2011 | Option Exercise | 29,580 |
| BMRN | Chief Executive Officer | May 04, 2011 | Sale | 70,547 |
| BMRN | Chief Executive Officer | May 03, 2011 | Sale | 134,266 |
| BMRN | Chief Executive Officer | Jan 18, 2011 | Sale | 93,030 |
| BMRN | Chief Executive Officer | Dec 13, 2010 | Option Exercise | 6,460 |
| BMRN | Chief Executive Officer | Dec 13, 2010 | Sale | 27,429 |
| BMRN | Chief Executive Officer | Dec 06, 2010 | Option Exercise | 12,920 |
| BMRN | Chief Executive Officer | Dec 06, 2010 | Sale | 54,348 |
| BMRN | Chief Executive Officer | Dec 06, 2010 | Option Exercise | 6,460 |
| BMRN | Chief Executive Officer | Dec 06, 2010 | Sale | 27,174 |
| BMRN | Chief Executive Officer | Nov 23, 2010 | Option Exercise | 6,460 |
| BMRN | Chief Executive Officer | Nov 23, 2010 | Sale | 27,021 |
| BMRN | Chief Executive Officer | Nov 18, 2010 | Option Exercise | 6,460 |
| BMRN | Chief Executive Officer | Nov 18, 2010 | Sale | 25,988 |
| BMRN | Chief Executive Officer | Nov 08, 2010 | Option Exercise | 12,920 |
| BMRN | Chief Executive Officer | Nov 08, 2010 | Sale | 51,569 |
| BMRN | Chief Executive Officer | Nov 02, 2010 | Option Exercise | 12,920 |
| BMRN | Chief Executive Officer | Nov 03, 2010 | Option Exercise | 25,840 |
| BMRN | Chief Executive Officer | Nov 02, 2010 | Sale | 89,750 |
| BMRN | Chief Executive Officer | Nov 03, 2010 | Sale | 101,824 |
| BMRN | Chief Executive Officer | Sep 08, 2010 | Option Exercise | 6,460 |
| BMRN | Chief Executive Officer | Sep 08, 2010 | Sale | 22,220 |
| BMRN | Chief Executive Officer | Sep 02, 2010 | Sale | 20,890 |
| BMRN | Chief Executive Officer | Sep 01, 2010 | Sale | 63,000 |
| BMRN | Chief Executive Officer | Aug 30, 2010 | Option Exercise | 19,380 |
| BMRN | Chief Executive Officer | Aug 30, 2010 | Sale | 62,125 |
| BMRN | Chief Executive Officer | Aug 27, 2010 | Option Exercise | 19,380 |
| BMRN | Chief Executive Officer | Aug 27, 2010 | Sale | 62,028 |
| BMRN | Chief Executive Officer | Aug 30, 2010 | Option Exercise | 19,380 |
| BMRN | Chief Executive Officer | Aug 30, 2010 | Sale | 62,125 |