| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| NLTX | Director | Aug 17, 2023 | Buy | $0.69 | 166,942 | 115,617 | 5,612,949 | Aug 17, 2023, 05:08 PM |
| NLTX | Director | Aug 16, 2023 | Buy | $0.68 | 229,600 | 156,254 | 5,458,724 | Aug 17, 2023, 05:08 PM |
| NLTX | Director | Aug 15, 2023 | Buy | $0.63 | 1,888,800 | 1,191,616 | 5,246,614 | Aug 17, 2023, 05:08 PM |
| ACAD | Director | May 23, 2023 | Option Exercise | $17.01 | 25,000 | 425,250 | 38,620,261 | May 24, 2023, 05:09 PM |
| ACAD | Director | May 22, 2023 | Buy | $24.57 | 134,206 | 3,297,815 | 38,607,761 | May 24, 2023, 05:09 PM |
| ACAD | Director | May 24, 2023 | Buy | $25.48 | 553,263 | 14,096,825 | 39,317,673 | May 24, 2023, 05:09 PM |
| ACAD | Director | May 23, 2023 | Buy | $25.41 | 209,053 | 5,312,458 | 38,811,515 | May 24, 2023, 05:09 PM |
| SGEN | Director | May 01, 2023 | Option Exercise | $36.70 | 17,500 | 642,250 | 42,975,257 | May 03, 2023, 04:04 PM |
| INCY | Director | Mar 13, 2023 | Option Exercise | $22.74 | 40,000 | 909,600 | 33,442,926 | Mar 15, 2023, 04:03 PM |
| ACAD | Director | Jan 12, 2023 | Option Exercise | $5.22 | 30,000 | 156,600 | 38,484,981 | Jan 17, 2023, 04:22 PM |
| KOD | Director | Jun 03, 2022 | Buy | $7.95 | 102,200 | 812,481 | 15,695,640 | Jun 06, 2022, 05:08 PM |
| KOD | Director | Jun 02, 2022 | Buy | $7.67 | 166,232 | 1,274,594 | 15,604,214 | Jun 06, 2022, 05:08 PM |
| KOD | Director | Jun 06, 2022 | Buy | $7.77 | 303,917 | 2,361,093 | 15,967,504 | Jun 06, 2022, 05:08 PM |
| TRDA | 10% Owner | Jun 06, 2022 | Buy | $6.41 | 38,304 | 245,377 | 4,501,658 | Jun 06, 2022, 05:07 PM |
| TRDA | 10% Owner | Jun 02, 2022 | Buy | $5.82 | 2,643 | 15,383 | 4,467,393 | Jun 06, 2022, 05:07 PM |
| KOD | Director | May 27, 2022 | Buy | $6.87 | 155,940 | 1,071,030 | 15,455,507 | May 27, 2022, 04:44 PM |
| KOD | Director | May 26, 2022 | Buy | $6.74 | 93,322 | 628,583 | 15,316,021 | May 27, 2022, 04:44 PM |
| KOD | Director | May 25, 2022 | Buy | $6.57 | 101,144 | 664,135 | 15,232,546 | May 27, 2022, 04:44 PM |
| TRDA | 10% Owner | May 24, 2022 | Buy | $5.75 | 23,823 | 137,100 | 4,465,029 | May 24, 2022, 06:39 PM |
| TRDA | 10% Owner | May 23, 2022 | Buy | $5.99 | 7,837 | 46,923 | 4,443,719 | May 24, 2022, 06:39 PM |
| TRDA | 10% Owner | May 20, 2022 | Buy | $5.84 | 16,849 | 98,424 | 4,436,709 | May 24, 2022, 06:39 PM |
| TRDA | 10% Owner | May 18, 2022 | Buy | $6.00 | 34,433 | 206,534 | 4,421,689 | May 18, 2022, 05:38 PM |
| TRDA | 10% Owner | May 17, 2022 | Buy | $6.13 | 18,511 | 113,474 | 4,390,994 | May 18, 2022, 05:38 PM |
| TRDA | 10% Owner | May 16, 2022 | Buy | $5.83 | 19,000 | 110,692 | 4,374,493 | May 18, 2022, 05:38 PM |
| KOD | Director | May 18, 2022 | Buy | $5.97 | 223,766 | 1,335,419 | 15,142,074 | May 18, 2022, 05:30 PM |
| KOD | Director | May 17, 2022 | Buy | $5.99 | 110,824 | 663,571 | 14,942,601 | May 18, 2022, 05:30 PM |
| KOD | Director | May 16, 2022 | Buy | $5.72 | 122,100 | 697,839 | 14,843,809 | May 18, 2022, 05:30 PM |
| TCRX | Director | May 11, 2022 | Buy | $1.99 | 25,865 | 51,350 | 2,528,583 | May 12, 2022, 04:41 PM |
| TCRX | Director | May 10, 2022 | Buy | $1.88 | 1,333,927 | 2,507,804 | 2,505,600 | May 12, 2022, 04:41 PM |
| INCY | Director | Mar 08, 2022 | Option Exercise | $22.05 | 40,000 | 882,000 | 33,059,604 | Mar 10, 2022, 06:02 PM |
| INCY | Director | Mar 09, 2022 | Buy | $71.72 | 70,517 | 5,057,550 | 33,217,136 | Mar 10, 2022, 06:02 PM |
| INCY | Director | Mar 08, 2022 | Buy | $70.68 | 100,000 | 7,067,500 | 33,151,989 | Mar 10, 2022, 06:02 PM |
| INCY | Director | Mar 10, 2022 | Buy | $73.13 | 218,563 | 15,982,720 | 33,419,055 | Mar 10, 2022, 06:02 PM |
| SGEN | Director | Mar 08, 2022 | Option Exercise | $20.06 | 35,000 | 702,100 | 42,965,004 | Mar 10, 2022, 04:39 PM |
| INCY | Director | Feb 22, 2022 | Buy | $68.07 | 99,800 | 6,793,536 | 33,039,604 | Feb 22, 2022, 05:45 PM |
| INCY | Director | Feb 18, 2022 | Buy | $68.38 | 133,032 | 9,096,550 | 32,947,370 | Feb 22, 2022, 05:45 PM |
| INCY | Director | Feb 17, 2022 | Buy | $67.74 | 292,972 | 19,844,806 | 32,824,461 | Feb 22, 2022, 05:45 PM |
| KOD | Director | Feb 16, 2022 | Buy | $54.12 | 95,165 | 5,150,173 | 14,457,794 | Feb 17, 2022, 05:33 PM |
| KOD | Director | Feb 15, 2022 | Buy | $54.15 | 5,800 | 314,099 | 14,369,871 | Feb 17, 2022, 05:33 PM |
| KOD | Director | Feb 17, 2022 | Buy | $54.56 | 300,000 | 16,367,881 | 14,734,965 | Feb 17, 2022, 05:33 PM |
| KOD | Director | Jan 31, 2022 | Buy | $57.22 | 30,148 | 1,725,084 | 14,364,512 | Jan 31, 2022, 05:06 PM |
| KOD | Director | Jan 28, 2022 | Buy | $50.42 | 55,258 | 2,786,084 | 14,336,671 | Jan 31, 2022, 05:06 PM |
| KOD | Director | Jan 27, 2022 | Buy | $51.76 | 262,259 | 13,573,519 | 14,285,631 | Jan 31, 2022, 05:06 PM |
| KOD | Director | Jan 24, 2022 | Buy | $57.72 | 362,197 | 20,905,291 | 14,022,337 | Jan 25, 2022, 05:40 PM |
| KOD | Director | Jan 21, 2022 | Buy | $56.80 | 133,414 | 7,577,571 | 13,660,140 | Jan 25, 2022, 05:40 PM |
| KOD | Director | Jan 25, 2022 | Buy | $58.90 | 5,500 | 323,934 | 14,027,837 | Jan 25, 2022, 05:40 PM |
| INCY | Director | Dec 17, 2021 | Buy | $72.80 | 1,075,872 | 78,322,147 | 30,932,696 | Dec 17, 2021, 06:30 PM |
| INCY | Director | Dec 16, 2021 | Buy | $71.96 | 169,315 | 12,184,412 | 29,856,824 | Dec 17, 2021, 06:30 PM |
| INCY | Director | Dec 15, 2021 | Buy | $71.51 | 350,332 | 25,052,340 | 29,687,509 | Dec 17, 2021, 06:30 PM |
| SGEN | Director | Dec 01, 2021 | Sale | $161.21 | 93,451 | 15,064,917 | 43,007,235 | Dec 02, 2021, 06:51 PM |
| SGEN | Director | Nov 30, 2021 | Sale | $160.33 | 301,444 | 48,331,458 | 43,100,476 | Dec 02, 2021, 06:51 PM |
| TLIS | Director | Nov 18, 2021 | Buy | $4.36 | 50,000 | 218,250 | 7,053,176 | Nov 19, 2021, 04:09 PM |
| KOD | Director | Sep 29, 2021 | Option Exercise | $102.00 | 16 | 1,632 | 13,439,794 | Oct 01, 2021, 04:58 PM |
| KOD | Director | Sep 29, 2021 | Option Exercise | $0.01 | 149,999 | 1,500 | 13,439,808 | Oct 01, 2021, 04:58 PM |
| KOD | Director | Sep 30, 2021 | Buy | $95.83 | 86,932 | 8,330,572 | 13,526,726 | Oct 01, 2021, 04:58 PM |
| KOD | Director | Sep 16, 2021 | Buy | $94.59 | 1,153 | 109,064 | 13,300,993 | Sep 17, 2021, 06:05 PM |
| KOD | Director | Sep 15, 2021 | Buy | $94.39 | 30,685 | 2,896,217 | 13,299,840 | Sep 17, 2021, 06:05 PM |
| KOD | Director | Sep 07, 2021 | Buy | $93.31 | 57,501 | 5,365,227 | 13,269,155 | Sep 09, 2021, 06:43 PM |
| KOD | Director | Aug 19, 2021 | Buy | $87.56 | 83,648 | 7,323,898 | 13,211,654 | Aug 19, 2021, 05:12 PM |
| KOD | Director | Aug 18, 2021 | Buy | $87.89 | 22,584 | 1,984,806 | 13,128,006 | Aug 19, 2021, 05:12 PM |
| KOD | Director | Aug 17, 2021 | Buy | $85.90 | 8,164 | 701,254 | 13,105,422 | Aug 19, 2021, 05:12 PM |
| KOD | Director | Aug 11, 2021 | Buy | $86.11 | 53,523 | 4,609,090 | 13,048,008 | Aug 13, 2021, 07:14 PM |
| KOD | Director | Aug 13, 2021 | Buy | $88.66 | 38,264 | 3,392,579 | 13,097,258 | Aug 13, 2021, 07:14 PM |
| KOD | Director | Aug 12, 2021 | Buy | $87.29 | 10,986 | 958,954 | 13,058,994 | Aug 13, 2021, 07:14 PM |
| TCRX | Director | Jul 20, 2021 | Buy | $15.00 | 1,425,000 | 21,375,000 | 1,320,302 | Jul 22, 2021, 04:06 PM |
| KOD | Director | Jun 30, 2021 | Buy | $92.24 | 155,577 | 14,350,693 | 12,994,485 | Jun 30, 2021, 07:29 PM |
| KOD | Director | Jun 29, 2021 | Buy | $90.46 | 54,078 | 4,892,033 | 12,838,908 | Jun 30, 2021, 07:29 PM |
| KOD | Director | Jun 28, 2021 | Buy | $91.43 | 48,274 | 4,413,705 | 12,784,830 | Jun 30, 2021, 07:29 PM |
| TLIS | Director | Feb 17, 2021 | Buy | $16.00 | 6,250,000 | 100,000,000 | 7,003,176 | Feb 19, 2021, 06:17 PM |
| PRLD | Director | Jan 27, 2021 | Option Exercise | $12.85 | 10,376 | 133,332 | 9,252,951 | Jan 29, 2021, 07:04 PM |
| IGMS | Director | Jan 27, 2021 | Option Exercise | $28.63 | 22,420 | 641,854 | 2,895,306 | Jan 29, 2021, 07:03 PM |
| BGNE | Director | Jan 04, 2021 | Sale | $220.50 | 121,154 | 26,714,457 | 10,699,954 | Jan 06, 2021, 06:32 PM |
| NLTX | Director | Jul 07, 2020 | Buy | $15.25 | 424,000 | 6,466,000 | 3,501,691 | Dec 23, 2020, 07:31 PM |
| BGNE | Director | Dec 04, 2020 | Sale | $220.50 | 1,511,546 | 333,295,893 | 10,811,048 | Dec 04, 2020, 05:24 PM |
| KOD | Director | Nov 20, 2020 | Buy | $108.00 | 1,527,777 | 164,999,916 | 12,736,556 | Nov 24, 2020, 04:09 PM |
| PRLD | Director | Sep 29, 2020 | Buy | $19.00 | 1,578,947 | 29,999,993 | 9,247,763 | Sep 30, 2020, 06:37 PM |
| KOD | Director | Sep 25, 2020 | Buy | $56.65 | 48,125 | 2,726,182 | 11,324,937 | Sep 25, 2020, 06:02 PM |
| KOD | Director | Sep 24, 2020 | Buy | $52.02 | 36,020 | 1,873,924 | 11,280,001 | Sep 24, 2020, 07:30 PM |
| KOD | Director | Sep 23, 2020 | Buy | $52.43 | 92,069 | 4,826,756 | 11,246,368 | Sep 24, 2020, 07:30 PM |
| KOD | Director | Sep 22, 2020 | Buy | $50.67 | 74,958 | 3,797,911 | 11,160,400 | Sep 24, 2020, 07:30 PM |
| KOD | Director | Sep 08, 2020 | Buy | $47.34 | 116,295 | 5,505,934 | 11,090,409 | Sep 08, 2020, 05:58 PM |
| KOD | Director | Sep 04, 2020 | Buy | $46.73 | 82,801 | 3,869,474 | 10,982,772 | Sep 08, 2020, 05:58 PM |
| KOD | Director | Sep 03, 2020 | Buy | $47.97 | 123,883 | 5,942,904 | 10,905,982 | Sep 08, 2020, 05:58 PM |
| KOD | Director | Aug 21, 2020 | Buy | $48.63 | 139,044 | 6,762,056 | 10,791,092 | Aug 21, 2020, 05:19 PM |
| KOD | Director | Aug 20, 2020 | Buy | $47.40 | 60,573 | 2,871,156 | 10,662,260 | Aug 21, 2020, 05:19 PM |
| KOD | Director | Aug 19, 2020 | Buy | $46.99 | 3,869 | 181,791 | 10,606,135 | Aug 21, 2020, 05:19 PM |
| BGNE | Director | Jul 15, 2020 | Option Exercise | $14.23 | 14,584,180 | 207,544,544 | 18,840,379 | Jul 17, 2020, 05:23 PM |
| INCY | Director | May 28, 2020 | Buy | $102.55 | 2 | 205 | 29,313,198 | May 28, 2020, 08:07 PM |
| SGEN | Director | May 15, 2020 | Sale | $160.00 | 1,750,000 | 280,000,000 | 43,288,836 | May 19, 2020, 06:03 PM |
| SGEN | Director | May 08, 2020 | Sale | $158.50 | 500,000 | 79,250,000 | 44,891,148 | May 08, 2020, 05:47 PM |
| SGEN | Director | May 07, 2020 | Sale | $164.41 | 168,244 | 27,660,924 | 45,486,837 | May 08, 2020, 05:47 PM |
| SGEN | Director | May 06, 2020 | Sale | $165.04 | 390,072 | 64,379,426 | 45,814,543 | May 08, 2020, 05:47 PM |
| INCY | Director | Apr 28, 2020 | Option Exercise | $13.34 | 40,000 | 533,600 | 29,311,915 | Apr 29, 2020, 04:45 PM |
| SGEN | Director | Apr 23, 2020 | Option Exercise | $12.76 | 35,000 | 446,600 | 45,860,149 | Apr 24, 2020, 04:25 PM |
| INCY | Director | Mar 31, 2020 | Option Exercise | $73.23 | 784 | 57,412 | 29,291,915 | Apr 01, 2020, 07:36 PM |
| ACAD | Director | Mar 18, 2020 | Buy | $33.52 | 135,897 | 4,555,101 | 38,433,977 | Mar 18, 2020, 06:47 PM |
| ACAD | Director | Mar 17, 2020 | Buy | $32.84 | 219,800 | 7,218,907 | 38,309,339 | Mar 18, 2020, 06:47 PM |
| ACAD | Director | Mar 16, 2020 | Buy | $31.51 | 694,303 | 21,878,017 | 38,107,749 | Mar 18, 2020, 06:47 PM |
| KOD | Director | Mar 18, 2020 | Buy | $37.37 | 35,400 | 1,322,977 | 10,602,550 | Mar 18, 2020, 06:47 PM |
| KOD | Director | Mar 17, 2020 | Buy | $38.99 | 10,000 | 389,850 | 10,570,083 | Mar 18, 2020, 06:47 PM |
| KOD | Director | Mar 16, 2020 | Buy | $39.97 | 104,600 | 4,180,977 | 10,560,911 | Mar 18, 2020, 06:47 PM |
| ALXN | Director | Mar 18, 2020 | Buy | $82.01 | 81,379 | 6,673,935 | 7,841,556 | Mar 18, 2020, 06:46 PM |
| ALXN | Director | Mar 17, 2020 | Buy | $76.51 | 102,421 | 7,836,585 | 7,720,234 | Mar 18, 2020, 06:45 PM |
| ALXN | Director | Mar 16, 2020 | Buy | $78.76 | 265,298 | 20,894,753 | 7,626,298 | Mar 18, 2020, 06:45 PM |
| ALXN | Director | Mar 18, 2020 | Buy | $79.76 | 50,902 | 4,059,792 | 7,766,918 | Mar 18, 2020, 06:45 PM |
| KOD | Director | Feb 26, 2020 | Buy | $57.99 | 100,000 | 5,799,441 | 10,464,977 | Feb 26, 2020, 05:06 PM |
| KOD | Director | Feb 25, 2020 | Buy | $57.91 | 206,126 | 11,937,248 | 10,373,248 | Feb 26, 2020, 05:06 PM |
| KOD | Director | Feb 24, 2020 | Buy | $57.56 | 71,123 | 4,093,553 | 10,184,170 | Feb 26, 2020, 05:06 PM |
| NLTX | Director | Dec 20, 2019 | Buy | $8.40 | 3,017,542 | 25,347,352 | 12,872,664 | Dec 20, 2019, 05:16 PM |
| KOD | Director | Dec 06, 2019 | Buy | $46.00 | 1,902,173 | 87,499,958 | 10,118,929 | Dec 06, 2019, 04:46 PM |
| GHDX | Director | Oct 01, 2019 | Option Exercise | $67.28 | 1,850 | 124,468 | 7,642,042 | Oct 03, 2019, 06:08 PM |
| INCY | Director | Sep 30, 2019 | Option Exercise | $74.23 | 728 | 54,039 | 29,291,207 | Oct 02, 2019, 05:15 PM |
| IGMS | Director | Sep 20, 2019 | Buy | $16.00 | 3,144,000 | 50,304,000 | 2,883,204 | Sep 20, 2019, 04:29 PM |
| ACAD | Director | Sep 20, 2019 | Buy | $40.00 | 1,562,500 | 62,500,000 | 37,470,965 | Sep 20, 2019, 04:28 PM |
| KOD | Director | Sep 19, 2019 | Option Exercise | $0.01 | 1 | 0 | 8,374,936 | Sep 20, 2019, 04:28 PM |
| AQXP | Director | Aug 07, 2019 | Buy | $3.05 | 289,725 | 882,884 | 10,105,159 | Aug 08, 2019, 05:00 PM |
| AQXP | Director | Aug 06, 2019 | Buy | $2.85 | 81,800 | 232,731 | 9,839,472 | Aug 08, 2019, 05:00 PM |
| GHDX | Director | Jul 01, 2019 | Option Exercise | $58.86 | 2,544 | 149,740 | 7,641,672 | Jul 03, 2019, 01:16 PM |
| IDRA | 10% Owner | Jul 01, 2019 | Option Exercise | $2.61 | 5,928 | 15,472 | 4,290,995 | Jul 03, 2019, 01:15 PM |
| INCY | Director | Jun 28, 2019 | Option Exercise | $84.96 | 620 | 52,675 | 29,290,843 | Jul 02, 2019, 04:05 PM |
| ALXN | Director | May 28, 2019 | Sale | $126.53 | 123,489 | 15,624,840 | 7,635,265 | May 30, 2019, 05:16 PM |
| ALXN | Director | May 30, 2019 | Sale | $120.97 | 57,449 | 6,949,741 | 7,418,911 | May 30, 2019, 05:16 PM |
| ALXN | Director | May 29, 2019 | Sale | $122.20 | 119,062 | 14,548,848 | 7,500,828 | May 30, 2019, 05:16 PM |
| SGEN | Director | Apr 29, 2019 | Option Exercise | $8.38 | 20,000 | 167,600 | 45,839,686 | May 01, 2019, 04:59 PM |
| HOOK | Former 10% owner | Apr 23, 2019 | Buy | $14.00 | 892,857 | 12,499,998 | 820,729 | Apr 23, 2019, 04:54 PM |
| GHDX | Director | Apr 12, 2019 | Sale | $65.32 | 11,204 | 731,889 | 7,639,338 | Apr 12, 2019, 05:02 PM |
| GHDX | Director | Apr 12, 2019 | Sale | $65.30 | 287,465 | 18,770,152 | 7,712,345 | Apr 12, 2019, 05:01 PM |
| GHDX | Director | Apr 11, 2019 | Sale | $66.90 | 202,281 | 13,533,252 | 7,991,484 | Apr 12, 2019, 05:01 PM |
| GHDX | Director | Apr 10, 2019 | Sale | $69.12 | 13,146 | 908,684 | 8,052,102 | Apr 10, 2019, 05:24 PM |
| GHDX | Director | Apr 10, 2019 | Sale | $68.70 | 124,542 | 8,556,110 | 8,062,934 | Apr 10, 2019, 05:24 PM |
| GHDX | Director | Apr 09, 2019 | Sale | $67.70 | 21,063 | 1,425,885 | 8,181,095 | Apr 10, 2019, 05:24 PM |
| GHDX | Director | Apr 08, 2019 | Sale | $67.90 | 22,648 | 1,537,720 | 8,182,908 | Apr 10, 2019, 05:24 PM |
| GHDX | Director | Apr 05, 2019 | Sale | $68.69 | 77,648 | 5,333,397 | 8,244,432 | Apr 05, 2019, 05:51 PM |
| GHDX | Director | Apr 04, 2019 | Sale | $66.64 | 81,053 | 5,401,340 | 8,265,548 | Apr 05, 2019, 05:51 PM |
| GHDX | Director | Apr 03, 2019 | Sale | $68.90 | 97,269 | 6,701,718 | 8,332,332 | Apr 05, 2019, 05:51 PM |
| IDRA | Director | Apr 01, 2019 | Option Exercise | $2.59 | 12,483 | 32,331 | 4,288,031 | Apr 03, 2019, 05:36 PM |
| GHDX | Director | Apr 01, 2019 | Option Exercise | $66.84 | 1,788 | 119,510 | 8,412,478 | Apr 03, 2019, 05:35 PM |
| INCY | Director | Mar 29, 2019 | Option Exercise | $86.01 | 660 | 56,767 | 29,289,013 | Apr 02, 2019, 05:21 PM |
| GHDX | Director | Mar 21, 2019 | Sale | $74.71 | 56,651 | 4,232,164 | 8,412,180 | Mar 25, 2019, 05:05 PM |
| GHDX | Director | Mar 19, 2019 | Sale | $74.34 | 50,100 | 3,724,594 | 8,458,858 | Mar 19, 2019, 05:48 PM |
| GHDX | Director | Mar 19, 2019 | Sale | $74.34 | 50,100 | 3,724,594 | 8,458,858 | Mar 19, 2019, 05:37 PM |
| GHDX | Director | Mar 19, 2019 | Sale | $74.63 | 105,126 | 7,845,648 | 8,500,139 | Mar 19, 2019, 05:31 PM |
| GHDX | Director | Mar 18, 2019 | Sale | $74.19 | 109,533 | 8,125,969 | 8,586,759 | Mar 19, 2019, 05:31 PM |
| GHDX | Director | Mar 15, 2019 | Sale | $74.64 | 55,347 | 4,131,088 | 8,719,547 | Mar 19, 2019, 05:31 PM |
| GHDX | Director | Mar 14, 2019 | Sale | $76.49 | 65,094 | 4,978,787 | 8,724,263 | Mar 14, 2019, 05:03 PM |
| GHDX | Director | Mar 13, 2019 | Sale | $75.92 | 80,253 | 6,092,923 | 8,839,544 | Mar 14, 2019, 05:03 PM |
| GHDX | Director | Mar 12, 2019 | Sale | $75.63 | 74,180 | 5,610,248 | 8,842,376 | Mar 14, 2019, 05:03 PM |
| GHDX | Director | Mar 11, 2019 | Sale | $75.00 | 49,035 | 3,677,484 | 8,906,794 | Mar 11, 2019, 04:59 PM |
| GHDX | Director | Mar 08, 2019 | Sale | $73.55 | 22,700 | 1,669,519 | 8,943,901 | Mar 11, 2019, 04:59 PM |
| GHDX | Director | Mar 07, 2019 | Sale | $73.72 | 2,000 | 147,445 | 8,962,604 | Mar 11, 2019, 04:59 PM |
| GHDX | Director | Mar 05, 2019 | Sale | $77.04 | 10,300 | 793,504 | 8,964,251 | Mar 05, 2019, 06:30 PM |
| GHDX | Director | Mar 04, 2019 | Sale | $76.49 | 27,811 | 2,127,250 | 8,972,737 | Mar 05, 2019, 06:30 PM |
| GHDX | Director | Mar 01, 2019 | Sale | $77.20 | 79,276 | 6,120,387 | 9,054,063 | Mar 05, 2019, 06:30 PM |
| GHDX | Director | Feb 28, 2019 | Sale | $76.20 | 600 | 45,719 | 9,060,972 | Feb 28, 2019, 06:22 PM |
| GHDX | Director | Feb 26, 2019 | Option Exercise | $17.59 | 16,500 | 290,235 | 9,100,815 | Feb 28, 2019, 06:21 PM |
| GHDX | Director | Feb 26, 2019 | Sale | $78.11 | 8,650 | 675,614 | 9,094,309 | Feb 28, 2019, 06:21 PM |
| GHDX | Director | Feb 27, 2019 | Sale | $76.65 | 39,109 | 2,997,792 | 9,062,207 | Feb 28, 2019, 06:21 PM |
| INCY | Director | Feb 26, 2019 | Option Exercise | $2.80 | 40,000 | 112,000 | 29,288,793 | Feb 27, 2019, 05:19 PM |
| GHDX | Director | Jan 28, 2019 | Sale | $71.07 | 46,477 | 3,302,980 | 9,106,199 | Jan 30, 2019, 04:00 PM |
| GHDX | Director | Jan 24, 2019 | Sale | $72.02 | 79,403 | 5,718,588 | 9,206,595 | Jan 25, 2019, 05:19 PM |
| GHDX | Director | Jan 23, 2019 | Sale | $70.67 | 37,512 | 2,651,092 | 9,273,669 | Jan 25, 2019, 05:19 PM |
| GHDX | Director | Jan 25, 2019 | Sale | $72.20 | 91,916 | 6,636,648 | 9,130,859 | Jan 25, 2019, 05:19 PM |
| GHDX | Director | Jan 22, 2019 | Sale | $71.00 | 51,606 | 3,664,031 | 9,302,929 | Jan 22, 2019, 05:27 PM |
| GHDX | Director | Jan 22, 2019 | Sale | $71.61 | 12,800 | 916,641 | 9,345,450 | Jan 22, 2019, 05:26 PM |
| GHDX | Director | Jan 18, 2019 | Sale | $72.73 | 177,142 | 12,884,344 | 9,369,592 | Jan 22, 2019, 05:26 PM |
| GHDX | Director | Jan 17, 2019 | Sale | $70.79 | 181,747 | 12,866,124 | 9,501,955 | Jan 22, 2019, 05:26 PM |
| GHDX | Director | Jan 11, 2019 | Sale | $70.22 | 28,474 | 1,999,533 | 9,652,202 | Jan 14, 2019, 05:11 PM |
| GHDX | Director | Jan 10, 2019 | Sale | $70.28 | 10,185 | 715,780 | 9,675,664 | Jan 14, 2019, 05:11 PM |
| GHDX | Director | Jan 14, 2019 | Sale | $70.07 | 600 | 42,043 | 9,651,709 | Jan 14, 2019, 05:11 PM |
| IDRA | Director | Jan 02, 2019 | Option Exercise | $3.52 | 10,974 | 38,628 | 4,283,870 | Jan 04, 2019, 04:52 PM |
| INCY | Director | Dec 31, 2018 | Option Exercise | $63.59 | 894 | 56,849 | 29,268,793 | Jan 02, 2019, 04:10 PM |
| GHDX | Director | Dec 12, 2018 | Sale | $73.09 | 18,500 | 1,352,087 | 9,683,746 | Dec 12, 2018, 05:57 PM |
| GHDX | Director | Dec 11, 2018 | Sale | $74.07 | 57,554 | 4,262,823 | 9,711,616 | Dec 12, 2018, 05:57 PM |
| GHDX | Director | Dec 10, 2018 | Sale | $73.83 | 9,366 | 691,483 | 9,746,410 | Dec 12, 2018, 05:57 PM |
| GHDX | Director | Dec 07, 2018 | Sale | $76.15 | 102,455 | 7,802,358 | 9,754,128 | Dec 07, 2018, 05:16 PM |
| GHDX | Director | Dec 06, 2018 | Sale | $75.46 | 92,679 | 6,993,622 | 9,838,546 | Dec 07, 2018, 05:16 PM |
| GHDX | Director | Dec 04, 2018 | Sale | $75.62 | 32,776 | 2,478,447 | 9,941,545 | Dec 07, 2018, 05:15 PM |
| ACAD | Director | Nov 30, 2018 | Buy | $17.00 | 11,764,705 | 199,999,985 | 35,976,940 | Dec 04, 2018, 05:00 PM |
| GHDX | Director | Dec 03, 2018 | Sale | $78.49 | 202,134 | 15,865,833 | 10,063,808 | Dec 03, 2018, 05:40 PM |
| GHDX | Director | Nov 30, 2018 | Sale | $79.20 | 204,757 | 16,217,023 | 10,237,588 | Dec 03, 2018, 05:39 PM |
| GHDX | Director | Nov 29, 2018 | Sale | $77.95 | 51,278 | 3,997,192 | 10,307,436 | Dec 03, 2018, 05:39 PM |
| GHDX | Director | Nov 28, 2018 | Sale | $75.61 | 250,392 | 18,932,284 | 10,468,980 | Nov 28, 2018, 05:44 PM |
| GHDX | Director | Nov 27, 2018 | Sale | $74.09 | 138,610 | 10,269,089 | 10,562,396 | Nov 28, 2018, 05:42 PM |
| GHDX | Director | Nov 26, 2018 | Sale | $74.28 | 39,675 | 2,947,113 | 10,648,158 | Nov 28, 2018, 05:42 PM |
| GHDX | Director | Nov 16, 2018 | Sale | $76.65 | 87,395 | 6,699,000 | 10,728,010 | Nov 20, 2018, 05:06 PM |
| GHDX | Director | Nov 13, 2018 | Sale | $79.69 | 114,858 | 9,153,058 | 10,786,282 | Nov 13, 2018, 06:35 PM |
| GHDX | Director | Nov 13, 2018 | Sale | $78.50 | 138,712 | 10,889,359 | 10,938,575 | Nov 13, 2018, 06:33 PM |
| GHDX | Director | Nov 12, 2018 | Sale | $81.07 | 65,588 | 5,317,265 | 11,000,100 | Nov 13, 2018, 06:33 PM |
| GHDX | Director | Nov 09, 2018 | Sale | $82.51 | 169,344 | 13,972,201 | 11,150,887 | Nov 13, 2018, 06:32 PM |
| GHDX | Director | Nov 12, 2018 | Sale | $80.38 | 14,415 | 1,158,724 | 11,007,633 | Nov 13, 2018, 06:32 PM |
| GHDX | Director | Nov 09, 2018 | Sale | $83.71 | 107,738 | 9,018,337 | 11,243,695 | Nov 13, 2018, 06:29 PM |
| GHDX | Director | Nov 08, 2018 | Sale | $86.50 | 76,273 | 6,597,504 | 11,280,104 | Nov 13, 2018, 06:26 PM |
| GHDX | Director | Nov 08, 2018 | Sale | $85.58 | 72,745 | 6,225,158 | 11,354,802 | Nov 13, 2018, 06:22 PM |
| KOD | Director | Oct 09, 2018 | Option Exercise | $5.00 | 791,187 | 3,955,935 | 5,359,406 | Oct 11, 2018, 05:57 PM |
| KOD | Director | Oct 09, 2018 | Buy | $10.00 | 2,500,000 | 25,000,000 | 8,374,935 | Oct 11, 2018, 05:57 PM |
| IDRA | Director | Oct 01, 2018 | Option Exercise | $8.71 | 7,020 | 61,144 | 4,280,212 | Oct 03, 2018, 08:37 PM |
| GHDX | Director | Oct 01, 2018 | Option Exercise | $70.18 | 1,704 | 119,587 | 11,370,600 | Oct 03, 2018, 07:43 PM |
| INCY | Director | Sep 28, 2018 | Option Exercise | $69.08 | 825 | 56,991 | 29,268,495 | Oct 02, 2018, 05:06 PM |
| ACAD | Director | Sep 20, 2018 | Buy | $18.70 | 1,210,776 | 22,646,990 | 24,798,117 | Sep 24, 2018, 08:32 AM |
| BGNE | Director | Aug 02, 2018 | Buy | $108.00 | 5,814,100 | 627,922,800 | 5,250,491 | Aug 06, 2018, 05:22 PM |
| IDRA | Director | Jul 02, 2018 | Option Exercise | $1.32 | 49,149 | 64,877 | 34,222,983 | Jul 05, 2018, 05:52 PM |
| INCY | Director | Jun 29, 2018 | Option Exercise | $67.00 | 849 | 56,883 | 29,268,220 | Jul 03, 2018, 03:32 PM |
| KNSA | Director | May 29, 2018 | Buy | $18.00 | 3,000,000 | 54,000,000 | 2,700,597 | May 31, 2018, 04:10 PM |
| SGEN | Director | May 18, 2018 | Option Exercise | $56.77 | 7,400 | 420,098 | 45,829,686 | May 18, 2018, 04:25 PM |
| SGEN | Director | May 04, 2018 | Buy | $52.68 | 204,537 | 10,775,582 | 45,569,872 | May 08, 2018, 05:17 PM |
| SGEN | Director | May 08, 2018 | Buy | $54.02 | 126,399 | 6,828,339 | 45,825,986 | May 08, 2018, 05:17 PM |
| SGEN | Director | May 07, 2018 | Buy | $53.70 | 129,715 | 6,966,305 | 45,699,587 | May 08, 2018, 05:17 PM |
| INCY | Director | May 02, 2018 | Option Exercise | $9.92 | 60,000 | 595,200 | 29,267,937 | May 03, 2018, 04:19 PM |
| SGEN | Director | May 01, 2018 | Option Exercise | $10.08 | 20,000 | 201,600 | 44,988,471 | May 02, 2018, 06:05 PM |
| SGEN | Director | May 02, 2018 | Buy | $52.57 | 69,947 | 3,676,836 | 45,365,335 | May 02, 2018, 06:05 PM |
| SGEN | Director | May 01, 2018 | Buy | $51.36 | 306,917 | 15,764,736 | 45,295,388 | May 02, 2018, 06:05 PM |
| SGEN | Director | Apr 30, 2018 | Buy | $51.06 | 623,136 | 31,816,925 | 44,978,471 | May 02, 2018, 06:05 PM |
| IDRA | Director | Apr 02, 2018 | Option Exercise | $1.62 | 40,047 | 64,876 | 34,206,600 | Apr 04, 2018, 04:55 PM |
| GHDX | Director | Apr 01, 2018 | Option Exercise | $31.29 | 3,828 | 119,778 | 11,369,920 | Apr 03, 2018, 06:01 PM |
| INCY | Director | Mar 29, 2018 | Option Exercise | $83.33 | 684 | 56,998 | 29,247,937 | Apr 02, 2018, 05:59 PM |
| NVTA | 10% Owner | Mar 28, 2018 | Buy | $4.50 | 1,111,111 | 5,000,000 | 7,480,182 | Mar 29, 2018, 03:59 PM |
| IDRA | Director | Mar 15, 2018 | Option Exercise | $0.47 | 20,316,327 | 9,548,674 | 34,193,251 | Mar 15, 2018, 04:10 PM |
| GHDX | Director | Mar 09, 2018 | Option Exercise | $18.50 | 49,500 | 915,750 | 11,369,282 | Mar 12, 2018, 06:04 PM |
| SGEN | Director | Feb 01, 2018 | Buy | $52.00 | 389,610 | 20,259,720 | 5,278,174 | Feb 05, 2018, 04:00 PM |
| SGEN | Director | Feb 01, 2018 | Buy | $52.00 | 3,456,543 | 179,740,236 | 44,355,335 | Feb 05, 2018, 04:00 PM |
| BGNE | Director | Jan 18, 2018 | Buy | $101.00 | 1,980,198 | 199,999,998 | 5,121,404 | Jan 22, 2018, 05:03 PM |
| BLCM | 10% Owner | Jan 19, 2018 | Sale | $7.91 | 295,361 | 2,336,217 | 3,734,776 | Jan 19, 2018, 04:57 PM |
| BLCM | 10% Owner | Jan 18, 2018 | Sale | $8.12 | 324,774 | 2,635,768 | 4,000,484 | Jan 19, 2018, 04:57 PM |
| BLCM | 10% Owner | Jan 17, 2018 | Sale | $8.63 | 260,600 | 2,247,910 | 4,292,652 | Jan 19, 2018, 04:57 PM |
| IDRA | Director | Jan 02, 2018 | Option Exercise | $2.21 | 27,999 | 61,878 | 16,566,806 | Jan 04, 2018, 04:04 PM |
| INCY | Director | Dec 29, 2017 | Option Exercise | $94.71 | 600 | 56,826 | 29,247,709 | Jan 03, 2018, 04:05 PM |
| ACAD | Director | Nov 27, 2017 | Option Exercise | $28.00 | 1,941 | 54,348 | 489,977 | Nov 29, 2017, 04:00 PM |
| ACAD | Director | Nov 27, 2017 | Option Exercise | $1.38 | 39,378 | 54,342 | 491,918 | Nov 29, 2017, 04:00 PM |
| MRTX | 10% Owner | Nov 08, 2017 | Option Exercise | $7.86 | 280,263 | 2,202,867 | 2,372,218 | Nov 13, 2017, 06:04 AM |
| IDRA | Director | Oct 26, 2017 | Buy | $1.50 | 8,000,000 | 12,000,000 | 16,557,473 | Oct 30, 2017, 05:12 PM |
| ACAD | Director | Oct 13, 2017 | Option Exercise | $35.40 | 55,457 | 1,963,178 | 23,708,408 | Oct 16, 2017, 05:15 PM |
| ACAD | Director | Oct 13, 2017 | Option Exercise | $1.38 | 1,426,590 | 1,968,694 | 23,763,865 | Oct 16, 2017, 05:15 PM |
| RYTM | Former 10% owner | Oct 05, 2017 | Buy | $17.00 | 885,000 | 15,045,000 | 1,878,242 | Oct 06, 2017, 03:58 PM |
| IDRA | Director | Oct 02, 2017 | Option Exercise | $2.28 | 27,135 | 61,868 | 9,352,821 | Oct 04, 2017, 07:22 PM |
| GHDX | Director | Oct 01, 2017 | Option Exercise | $32.09 | 3,732 | 119,760 | 11,360,448 | Oct 03, 2017, 05:39 PM |
| INCY | Director | Sep 29, 2017 | Option Exercise | $116.74 | 486 | 56,736 | 29,247,509 | Oct 03, 2017, 05:30 PM |
| INCY | Director | Sep 08, 2017 | Buy | $132.00 | 100,000 | 13,200,000 | 29,247,347 | Sep 08, 2017, 05:06 PM |
| BGNE | Director | Aug 11, 2017 | Buy | $71.00 | 176,056 | 12,499,976 | 3,476,256 | Aug 14, 2017, 03:49 PM |
| IDRA | Director | Jul 03, 2017 | Option Exercise | $1.75 | 35,361 | 61,882 | 9,343,776 | Jul 06, 2017, 04:06 PM |
| GHDX | Director | Jul 01, 2017 | Option Exercise | $32.55 | 3,684 | 119,914 | 11,359,826 | Jul 05, 2017, 06:19 PM |
| INCY | Director | Jun 30, 2017 | Option Exercise | $125.91 | 450 | 56,660 | 29,161,945 | Jul 05, 2017, 06:01 PM |
| ALXN | Director | Jun 15, 2017 | Buy | $117.33 | 656,387 | 77,012,514 | 7,645,906 | Jun 16, 2017, 04:04 PM |
| ALXN | Director | Jun 14, 2017 | Buy | $118.00 | 4,392 | 518,256 | 7,321,850 | Jun 16, 2017, 04:04 PM |
| ALXN | Director | Jun 14, 2017 | Buy | $116.32 | 1,348,955 | 156,915,230 | 7,317,906 | Jun 16, 2017, 04:03 PM |
| GHDX | Director | May 31, 2017 | Option Exercise | $18.13 | 49,500 | 897,435 | 11,359,212 | Jun 01, 2017, 05:19 PM |
| SGEN | Director | May 19, 2017 | Option Exercise | $66.60 | 3,700 | 246,420 | 40,898,792 | May 23, 2017, 05:11 PM |
| SGEN | Director | May 19, 2017 | Option Exercise | $66.60 | 3,700 | 246,420 | 4,888,564 | May 23, 2017, 05:11 PM |
| SGEN | Director | May 15, 2017 | Option Exercise | $10.20 | 20,000 | 204,000 | 40,895,092 | May 17, 2017, 05:26 PM |
| INCY | Director | Apr 27, 2017 | Option Exercise | $7.26 | 60,000 | 435,600 | 29,161,795 | Apr 28, 2017, 05:10 PM |
| IDRA | Director | Apr 03, 2017 | Option Exercise | $2.43 | 25,461 | 61,870 | 9,331,989 | Apr 05, 2017, 04:59 PM |
| INCY | Director | Mar 31, 2017 | Option Exercise | $133.67 | 426 | 56,943 | 29,141,795 | Apr 04, 2017, 07:33 PM |
| GHDX | Director | Apr 01, 2017 | Option Exercise | $31.49 | 3,804 | 119,788 | 11,350,962 | Apr 04, 2017, 07:32 PM |
| BLCM | 10% Owner | Mar 24, 2017 | Buy | $12.00 | 166,666 | 1,999,992 | 4,527,089 | Mar 28, 2017, 05:05 PM |
| AQXP | 10% Owner | Jan 09, 2017 | Buy | $17.18 | 398,062 | 6,836,813 | 9,764,459 | Jan 09, 2017, 06:46 PM |
| IDRA | Director | Jan 03, 2017 | Option Exercise | $1.50 | 42,507 | 63,761 | 9,323,502 | Jan 05, 2017, 07:00 PM |
| GHDX | Director | Jan 01, 2017 | Option Exercise | $29.39 | 4,080 | 119,911 | 11,350,328 | Jan 04, 2017, 06:30 PM |
| INCY | Director | Dec 30, 2016 | Option Exercise | $100.27 | 567 | 56,853 | 19,758,174 | Jan 04, 2017, 06:01 PM |
| BGNE | Director | Nov 18, 2016 | Buy | $32.00 | 1,760,495 | 56,335,840 | 3,317,977 | Nov 21, 2016, 06:13 PM |
| NVTA | 10% Owner | Nov 17, 2016 | Buy | $6.00 | 733,333 | 4,399,998 | 6,480,668 | Nov 18, 2016, 04:36 PM |
| SGEN | Director | Nov 08, 2016 | Buy | $59.46 | 326,300 | 19,403,299 | 40,885,092 | Nov 09, 2016, 04:37 PM |
| SGEN | Director | Nov 07, 2016 | Buy | $58.74 | 56,200 | 3,301,345 | 40,590,914 | Nov 09, 2016, 04:37 PM |
| SGEN | Director | Nov 03, 2016 | Buy | $56.43 | 198,433 | 11,196,763 | 40,540,247 | Nov 03, 2016, 06:12 PM |
| SGEN | Director | Nov 03, 2016 | Buy | $56.91 | 379,336 | 21,586,885 | 40,361,400 | Nov 03, 2016, 06:11 PM |
| SGEN | Director | Nov 02, 2016 | Buy | $56.15 | 466,619 | 26,200,958 | 40,019,506 | Nov 03, 2016, 06:11 PM |
| SGEN | Director | Nov 01, 2016 | Buy | $54.46 | 184,674 | 10,057,349 | 39,598,943 | Nov 03, 2016, 06:11 PM |
| IDRA | Director | Oct 07, 2016 | Buy | $2.00 | 3,250,000 | 6,500,000 | 9,309,333 | Oct 11, 2016, 05:45 PM |
| IDRA | Director | Oct 03, 2016 | Option Exercise | $2.56 | 24,897 | 63,736 | 6,380,737 | Oct 05, 2016, 04:30 PM |
| GHDX | Director | Sep 30, 2016 | Option Exercise | $28.92 | 4,140 | 119,729 | 11,349,648 | Oct 04, 2016, 06:35 PM |
| INCY | Director | Sep 30, 2016 | Option Exercise | $94.29 | 603 | 56,857 | 19,757,985 | Oct 04, 2016, 06:33 PM |
| AQXP | 10% Owner | Sep 20, 2016 | Buy | $12.25 | 2,783,605 | 34,110,452 | 9,404,467 | Sep 21, 2016, 04:28 PM |
| SGEN | Director | Sep 12, 2016 | Buy | $51.14 | 49,889 | 2,551,111 | 39,305,533 | Sep 13, 2016, 06:05 PM |
| SGEN | Director | Sep 09, 2016 | Buy | $50.42 | 256,220 | 12,917,842 | 39,260,675 | Sep 13, 2016, 06:05 PM |
| SGEN | Director | Sep 13, 2016 | Buy | $51.09 | 141,202 | 7,213,981 | 39,432,496 | Sep 13, 2016, 06:05 PM |
| SGEN | Director | Sep 08, 2016 | Buy | $50.12 | 211,093 | 10,579,529 | 39,030,368 | Sep 08, 2016, 05:39 PM |
| SGEN | Director | Sep 07, 2016 | Buy | $48.52 | 59,560 | 2,889,689 | 38,840,624 | Sep 08, 2016, 05:39 PM |
| SGEN | Director | Sep 06, 2016 | Buy | $45.90 | 143,363 | 6,580,527 | 4,643,343 | Sep 08, 2016, 05:39 PM |
| BCRX | 10% Owner | Aug 15, 2016 | Sale | $4.83 | 400,000 | 1,931,040 | 9,419,240 | Aug 16, 2016, 06:11 PM |
| BCRX | 10% Owner | Aug 12, 2016 | Sale | $5.02 | 3,645,600 | 18,315,817 | 10,059,679 | Aug 16, 2016, 06:11 PM |
| BCRX | 10% Owner | Aug 16, 2016 | Sale | $4.29 | 990 | 4,246 | 9,418,390 | Aug 16, 2016, 06:11 PM |
| GHDX | Director | Aug 15, 2016 | Buy | $27.02 | 100,000 | 2,701,590 | 11,348,958 | Aug 15, 2016, 06:02 PM |
| ACAD | Director | Aug 10, 2016 | Buy | $33.00 | 1,303,030 | 42,999,990 | 22,337,275 | Aug 12, 2016, 04:08 PM |
| GHDX | Director | Jul 01, 2016 | Option Exercise | $26.74 | 4,476 | 119,688 | 11,259,062 | Jul 06, 2016, 06:22 PM |
| IDRA | Director | Jul 01, 2016 | Option Exercise | $1.63 | 39,114 | 63,756 | 6,372,438 | Jul 06, 2016, 06:21 PM |
| INCY | Director | Jun 30, 2016 | Option Exercise | $79.98 | 711 | 56,866 | 19,757,784 | Jul 05, 2016, 05:13 PM |
| MRTX | 10% Owner | Jun 09, 2016 | Sale | $9.45 | 545,058 | 5,150,516 | 2,281,101 | Jun 09, 2016, 05:06 PM |
| MRTX | 10% Owner | Jun 08, 2016 | Sale | $9.21 | 158,100 | 1,456,481 | 2,631,020 | Jun 09, 2016, 05:06 PM |
| MRTX | 10% Owner | Jun 07, 2016 | Sale | $9.44 | 296,200 | 2,795,476 | 2,778,549 | Jun 09, 2016, 05:06 PM |
| SGEN | Director | May 20, 2016 | Option Exercise | $38.82 | 7,400 | 287,268 | 38,787,087 | May 24, 2016, 05:50 PM |
| GHDX | Director | May 17, 2016 | Option Exercise | $10.73 | 49,500 | 531,135 | 11,258,316 | May 19, 2016, 06:23 PM |
| NTLA | Former 10% owner | May 11, 2016 | Buy | $18.00 | 200,000 | 3,600,000 | 976,214 | May 11, 2016, 04:25 PM |
| IDRA | Director | Apr 01, 2016 | Option Exercise | $1.97 | 32,364 | 63,757 | 6,359,400 | Apr 05, 2016, 06:00 PM |
| GHDX | Director | Apr 01, 2016 | Option Exercise | $25.48 | 4,704 | 119,858 | 11,250,066 | Apr 05, 2016, 05:58 PM |
| INCY | Director | Mar 31, 2016 | Option Exercise | $72.47 | 786 | 56,961 | 19,757,547 | Apr 04, 2016, 06:32 PM |
| MRTX | 10% Owner | Mar 30, 2016 | Option Exercise | $6.74 | 313,482 | 2,112,869 | 3,054,055 | Apr 01, 2016, 04:22 PM |
| MRTX | 10% Owner | Mar 30, 2016 | Option Exercise | $6.74 | 274 | 1,847 | 137 | Apr 01, 2016, 04:22 PM |
| ACAD | Director | Mar 30, 2016 | Buy | $25.94 | 462,546 | 12,000,056 | 2,799,646 | Apr 01, 2016, 04:21 PM |
| ACAD | Director | Apr 01, 2016 | Buy | $28.52 | 302,900 | 8,638,572 | 21,167,398 | Apr 01, 2016, 04:21 PM |
| ACAD | Director | Mar 31, 2016 | Buy | $27.21 | 683,644 | 18,601,181 | 20,894,327 | Apr 01, 2016, 04:21 PM |
| SGEN | Director | Mar 17, 2016 | Buy | $31.85 | 124,065 | 3,951,304 | 38,783,387 | Mar 21, 2016, 04:32 PM |
| INCY | Director | Mar 17, 2016 | Option Exercise | $3.86 | 60,000 | 231,600 | 19,396,568 | Mar 17, 2016, 07:14 PM |
| INCY | Director | Mar 17, 2016 | Buy | $61.49 | 400,000 | 24,595,777 | 19,757,285 | Mar 17, 2016, 07:14 PM |
| INCY | Director | Mar 15, 2016 | Buy | $66.47 | 400,000 | 26,588,417 | 19,376,568 | Mar 17, 2016, 07:14 PM |
| SGEN | Director | Mar 15, 2016 | Buy | $32.08 | 661,093 | 21,210,834 | 38,158,204 | Mar 16, 2016, 06:57 PM |
| SGEN | Director | Mar 14, 2016 | Buy | $33.77 | 118,941 | 4,016,519 | 37,562,036 | Mar 16, 2016, 06:57 PM |
| SGEN | Director | Mar 16, 2016 | Buy | $31.77 | 569,203 | 18,084,599 | 38,671,506 | Mar 16, 2016, 06:57 PM |
| AQXP | 10% Owner | Mar 16, 2016 | Buy | $8.00 | 361,755 | 2,893,570 | 6,928,119 | Mar 16, 2016, 06:56 PM |
| AQXP | 10% Owner | Mar 15, 2016 | Buy | $7.98 | 106,538 | 850,484 | 6,601,891 | Mar 16, 2016, 06:56 PM |
| AQXP | 10% Owner | Mar 15, 2016 | Buy | $7.88 | 3,374 | 26,582 | 781,421 | Mar 16, 2016, 06:56 PM |
| SGEN | Director | Mar 09, 2016 | Buy | $32.03 | 208,670 | 6,683,985 | 37,017,863 | Mar 11, 2016, 06:13 PM |
| SGEN | Director | Mar 11, 2016 | Buy | $33.10 | 195,765 | 6,480,738 | 37,454,776 | Mar 11, 2016, 06:13 PM |
| SGEN | Director | Mar 10, 2016 | Buy | $32.34 | 290,231 | 9,386,567 | 37,278,782 | Mar 11, 2016, 06:13 PM |
| SGEN | Director | Mar 02, 2016 | Buy | $32.67 | 400,000 | 13,068,812 | 36,367,808 | Mar 02, 2016, 06:31 PM |
| SGEN | Director | Mar 01, 2016 | Buy | $31.24 | 24,200 | 756,112 | 36,007,250 | Mar 02, 2016, 06:31 PM |
| SGEN | Director | Feb 29, 2016 | Buy | $30.39 | 251,722 | 7,650,310 | 35,985,436 | Mar 02, 2016, 06:31 PM |
| SGEN | Director | Feb 26, 2016 | Buy | $30.13 | 44,300 | 1,334,945 | 35,758,535 | Feb 26, 2016, 05:42 PM |
| SGEN | Director | Feb 25, 2016 | Buy | $29.86 | 142,702 | 4,261,553 | 35,718,720 | Feb 26, 2016, 05:42 PM |
| SGEN | Director | Feb 24, 2016 | Buy | $28.99 | 127,506 | 3,696,568 | 35,590,465 | Feb 26, 2016, 05:42 PM |
| INCY | Director | Feb 25, 2016 | Buy | $74.00 | 6,700 | 495,800 | 19,015,852 | Feb 26, 2016, 04:42 PM |
| INCY | Director | Feb 24, 2016 | Buy | $70.41 | 57,590 | 4,055,187 | 19,009,830 | Feb 26, 2016, 04:42 PM |
| SGEN | Director | Feb 22, 2016 | Buy | $30.21 | 243,411 | 7,354,639 | 35,475,868 | Feb 22, 2016, 05:34 PM |
| SGEN | Director | Feb 19, 2016 | Buy | $29.20 | 506,526 | 14,790,560 | 35,257,100 | Feb 22, 2016, 05:34 PM |
| SGEN | Director | Feb 18, 2016 | Buy | $29.94 | 251,534 | 7,530,350 | 34,800,251 | Feb 22, 2016, 05:34 PM |
| SGEN | Director | Feb 16, 2016 | Buy | $29.80 | 270,163 | 8,049,663 | 33,847,095 | Feb 17, 2016, 06:05 PM |
| SGEN | Director | Feb 12, 2016 | Buy | $27.93 | 193,717 | 5,410,745 | 33,588,605 | Feb 17, 2016, 06:05 PM |
| SGEN | Director | Feb 17, 2016 | Buy | $31.25 | 805,267 | 25,161,937 | 34,573,386 | Feb 17, 2016, 06:05 PM |
| INCY | Director | Feb 16, 2016 | Buy | $70.71 | 678,488 | 47,973,375 | 18,958,070 | Feb 16, 2016, 08:14 PM |
| INCY | Director | Feb 12, 2016 | Buy | $67.14 | 208,677 | 14,010,425 | 18,346,124 | Feb 16, 2016, 08:14 PM |
| INCY | Director | Feb 12, 2016 | Buy | $65.83 | 922,530 | 60,732,037 | 18,158,080 | Feb 16, 2016, 08:13 PM |
| INCY | Director | Feb 11, 2016 | Buy | $61.93 | 1,328,897 | 82,297,659 | 17,326,770 | Feb 16, 2016, 08:13 PM |
| BGNE | Director | Feb 08, 2016 | Buy | $24.00 | 1,912,680 | 45,904,320 | 1,723,306 | Feb 09, 2016, 05:38 PM |
| BGNE | Director | Feb 08, 2016 | Option Exercise | $0.68 | 2,592,593 | 1,750,000 | 73,162,022 | Feb 09, 2016, 05:38 PM |
| BCRX | 10% Owner | Feb 05, 2016 | Buy | $6.33 | 45,000 | 284,656 | 12,894,240 | Feb 09, 2016, 05:24 PM |
| BCRX | 10% Owner | Feb 04, 2016 | Buy | $6.65 | 24,800 | 164,915 | 12,849,240 | Feb 04, 2016, 05:15 PM |
| BCRX | 10% Owner | Feb 03, 2016 | Buy | $6.29 | 91,187 | 573,311 | 12,824,440 | Feb 04, 2016, 05:15 PM |
| BCRX | 10% Owner | Feb 02, 2016 | Buy | $6.52 | 91,728 | 598,360 | 12,733,253 | Feb 04, 2016, 05:15 PM |
| BCRX | 10% Owner | Jan 28, 2016 | Buy | $6.88 | 25,000 | 172,015 | 12,641,525 | Jan 29, 2016, 04:42 PM |
| BCRX | 10% Owner | Jan 27, 2016 | Buy | $6.98 | 63,345 | 441,971 | 12,616,525 | Jan 29, 2016, 04:42 PM |
| AQXP | 10% Owner | Jan 26, 2016 | Buy | $10.81 | 77,639 | 839,524 | 6,502,773 | Jan 26, 2016, 06:53 PM |
| AQXP | 10% Owner | Jan 25, 2016 | Buy | $11.11 | 10,945 | 121,576 | 6,432,847 | Jan 26, 2016, 06:53 PM |
| AQXP | 10% Owner | Jan 22, 2016 | Buy | $10.72 | 50,315 | 539,465 | 6,422,989 | Jan 26, 2016, 06:53 PM |
| AQXP | 10% Owner | Jan 22, 2016 | Buy | $10.78 | 1,887 | 20,345 | 765,980 | Jan 26, 2016, 06:53 PM |
| BCRX | 10% Owner | Jan 21, 2016 | Buy | $7.29 | 103,600 | 755,368 | 12,549,980 | Jan 25, 2016, 06:10 PM |
| BCRX | 10% Owner | Jan 22, 2016 | Buy | $7.00 | 3,200 | 22,389 | 12,553,180 | Jan 25, 2016, 06:10 PM |
| BCRX | 10% Owner | Jan 20, 2016 | Buy | $6.87 | 52,695 | 362,171 | 12,446,380 | Jan 20, 2016, 07:13 PM |
| BCRX | 10% Owner | Jan 19, 2016 | Buy | $7.12 | 92,200 | 656,750 | 12,393,685 | Jan 20, 2016, 07:13 PM |
| BCRX | 10% Owner | Jan 15, 2016 | Buy | $7.46 | 200,000 | 1,491,222 | 12,301,485 | Jan 20, 2016, 07:13 PM |
| AQXP | 10% Owner | Jan 19, 2016 | Buy | $9.08 | 5,029 | 45,642 | 750,354 | Jan 20, 2016, 07:12 PM |
| AQXP | 10% Owner | Jan 20, 2016 | Buy | $9.48 | 112,034 | 1,062,538 | 6,375,941 | Jan 20, 2016, 07:12 PM |
| AQXP | 10% Owner | Jan 19, 2016 | Buy | $9.11 | 73,016 | 665,474 | 6,274,969 | Jan 20, 2016, 07:12 PM |
| AQXP | 10% Owner | Jan 15, 2016 | Buy | $8.47 | 84,670 | 717,201 | 6,204,630 | Jan 15, 2016, 05:37 PM |
| AQXP | 10% Owner | Jan 14, 2016 | Buy | $8.13 | 107,983 | 878,410 | 6,128,358 | Jan 15, 2016, 05:37 PM |
| AQXP | 10% Owner | Jan 14, 2016 | Buy | $8.17 | 9,970 | 81,472 | 735,198 | Jan 15, 2016, 05:37 PM |
| AQXP | 10% Owner | Jan 15, 2016 | Buy | $8.47 | 84,670 | 717,201 | 6,204,630 | Jan 15, 2016, 05:13 PM |
| AQXP | 10% Owner | Jan 14, 2016 | Buy | $8.13 | 107,983 | 878,410 | 6,128,358 | Jan 15, 2016, 05:13 PM |
| AQXP | 10% Owner | Jan 14, 2016 | Buy | $8.17 | 9,970 | 81,472 | 735,198 | Jan 15, 2016, 05:13 PM |
| ACAD | Director | Jan 07, 2016 | Buy | $29.00 | 2,586,206 | 74,999,974 | 20,278,008 | Jan 08, 2016, 07:07 PM |
| ACAD | Director | Jan 07, 2016 | Buy | $29.00 | 2,586,206 | 74,999,974 | 20,278,008 | Jan 08, 2016, 06:07 PM |
| IDRA | Director | Jan 04, 2016 | Option Exercise | $3.00 | 21,246 | 63,738 | 6,348,612 | Jan 06, 2016, 06:02 PM |
| GHDX | Director | Jan 01, 2016 | Option Exercise | $35.20 | 3,408 | 119,962 | 11,249,282 | Jan 05, 2016, 06:47 PM |
| INCY | Director | Dec 31, 2015 | Option Exercise | $108.45 | 525 | 56,936 | 16,129,274 | Jan 05, 2016, 06:22 PM |
| SGEN | Director | Nov 20, 2015 | Buy | $43.98 | 181,647 | 7,988,259 | 33,428,852 | Nov 20, 2015, 05:02 PM |
| SGEN | Director | Nov 19, 2015 | Buy | $43.93 | 133,073 | 5,845,378 | 33,247,205 | Nov 20, 2015, 05:02 PM |
| SGEN | Director | Nov 18, 2015 | Buy | $43.61 | 14,638 | 638,321 | 33,114,132 | Nov 20, 2015, 05:02 PM |
| SGEN | Director | Nov 06, 2015 | Buy | $41.94 | 417,924 | 17,529,497 | 32,582,794 | Nov 10, 2015, 07:57 PM |
| SGEN | Director | Nov 10, 2015 | Buy | $44.00 | 9,400 | 413,600 | 33,099,494 | Nov 10, 2015, 07:57 PM |
| SGEN | Director | Nov 09, 2015 | Buy | $43.76 | 507,300 | 22,200,588 | 33,090,094 | Nov 10, 2015, 07:57 PM |
| GHDX | Director | Oct 01, 2015 | Option Exercise | $21.34 | 5,616 | 119,845 | 11,248,714 | Oct 05, 2015, 07:17 PM |
| INCY | Director | Oct 01, 2015 | Option Exercise | $110.33 | 516 | 56,930 | 16,129,099 | Oct 05, 2015, 07:04 PM |
| IDRA | Director | Oct 01, 2015 | Option Exercise | $3.06 | 20,835 | 63,755 | 6,341,530 | Oct 05, 2015, 06:59 PM |
| SGEN | Director | Sep 11, 2015 | Buy | $41.43 | 4,212,787 | 174,517,109 | 31,218,173 | Sep 15, 2015, 07:04 PM |
| SGEN | Director | Sep 15, 2015 | Buy | $48.28 | 626,259 | 30,237,807 | 32,164,870 | Sep 15, 2015, 07:04 PM |
| SGEN | Director | Sep 14, 2015 | Buy | $46.34 | 320,438 | 14,849,199 | 31,538,611 | Sep 15, 2015, 07:04 PM |
| AQXP | 10% Owner | Sep 10, 2015 | Buy | $15.50 | 2,213,469 | 34,308,770 | 6,022,104 | Sep 11, 2015, 04:11 PM |
| AQXP | 10% Owner | Sep 10, 2015 | Buy | $15.50 | 266,563 | 4,131,727 | 725,228 | Sep 11, 2015, 04:11 PM |
| XOMA | Former 10% owner | Jul 22, 2015 | Sale | $1.09 | 11,000,000 | 12,017,500 | 3,153,539 | Jul 23, 2015, 05:35 PM |
| IDRA | Director | Jul 01, 2015 | Option Exercise | $3.66 | 15,780 | 57,755 | 6,334,585 | Jul 06, 2015, 06:25 PM |
| GHDX | Director | Jul 01, 2015 | Option Exercise | $27.34 | 4,380 | 119,749 | 11,247,778 | Jul 06, 2015, 05:42 PM |
| INCY | Director | Jul 01, 2015 | Option Exercise | $104.21 | 546 | 56,899 | 12,485,965 | Jul 06, 2015, 05:40 PM |
| SGEN | Director | May 21, 2015 | Buy | $43.38 | 362,459 | 15,723,084 | 27,005,386 | May 21, 2015, 07:42 PM |
| SGEN | Director | May 20, 2015 | Buy | $42.56 | 374,298 | 15,929,272 | 26,652,609 | May 21, 2015, 07:42 PM |
| SGEN | Director | May 19, 2015 | Buy | $40.87 | 214,129 | 8,751,249 | 26,268,629 | May 21, 2015, 07:42 PM |
| SGEN | Director | May 15, 2015 | Option Exercise | $39.94 | 7,400 | 295,556 | 26,054,500 | May 18, 2015, 06:45 PM |
| INCY | Director | May 11, 2015 | Option Exercise | $7.68 | 60,000 | 460,800 | 12,485,783 | May 12, 2015, 06:58 PM |
| SGEN | Director | May 11, 2015 | Option Exercise | $5.11 | 20,000 | 102,200 | 26,050,800 | May 12, 2015, 09:04 AM |
| SGEN | Director | May 07, 2015 | Buy | $37.15 | 47,717 | 1,772,790 | 26,040,800 | May 07, 2015, 09:32 PM |
| SGEN | Director | May 06, 2015 | Buy | $36.41 | 453,995 | 16,530,995 | 25,993,083 | May 07, 2015, 09:32 PM |
| SGEN | Director | May 05, 2015 | Buy | $34.69 | 530,952 | 18,419,925 | 25,539,088 | May 07, 2015, 09:32 PM |
| IDRA | Director | Apr 01, 2015 | Option Exercise | $3.52 | 16,410 | 57,763 | 6,329,325 | Apr 02, 2015, 07:09 PM |
| GHDX | Director | Apr 01, 2015 | Option Exercise | $30.43 | 3,936 | 119,772 | 11,247,048 | Apr 02, 2015, 06:37 PM |
| SGEN | Director | Mar 10, 2015 | Buy | $34.54 | 9,319 | 321,921 | 25,008,136 | Mar 11, 2015, 06:55 PM |
| SGEN | Director | Mar 09, 2015 | Buy | $34.66 | 275,717 | 9,556,609 | 24,998,817 | Mar 11, 2015, 06:55 PM |
| SGEN | Director | Feb 25, 2015 | Buy | $34.48 | 63,650 | 2,194,758 | 24,274,259 | Feb 26, 2015, 07:12 PM |
| SGEN | Director | Feb 24, 2015 | Buy | $33.76 | 217,465 | 7,341,491 | 24,210,609 | Feb 26, 2015, 07:12 PM |
| IDRA | Director | Feb 13, 2015 | Buy | $3.75 | 5,333,333 | 19,999,999 | 6,323,855 | Feb 17, 2015, 07:39 AM |
| MRTX | 10% Owner | Jan 29, 2015 | Buy | $20.00 | 425,000 | 8,500,000 | 2,604,832 | Feb 02, 2015, 05:33 PM |
| GEVA | Director | Jan 07, 2015 | Buy | $94.19 | 1,000,000 | 94,190,002 | 9,184,771 | Jan 09, 2015, 05:28 PM |
| IDRA | Director | Jan 02, 2015 | Option Exercise | $4.90 | 11,781 | 57,727 | 1,425,446 | Jan 06, 2015, 08:32 PM |
| XOMA | Director | Jan 06, 2015 | Sale | $3.86 | 1,000,000 | 3,860,000 | 12,589,950 | Jan 06, 2015, 08:31 PM |
| XOMA | Director | Jan 05, 2015 | Sale | $3.81 | 1,003,300 | 3,824,078 | 13,449,938 | Jan 06, 2015, 08:31 PM |
| XOMA | Director | Jan 02, 2015 | Sale | $3.55 | 212,100 | 753,740 | 14,313,038 | Jan 06, 2015, 08:31 PM |
| XOMA | Director | Dec 30, 2014 | Sale | $3.65 | 391,900 | 1,430,239 | 14,495,492 | Dec 30, 2014, 05:40 PM |
| XOMA | Director | Dec 29, 2014 | Sale | $3.68 | 221,000 | 812,440 | 14,832,615 | Dec 30, 2014, 05:40 PM |
| XOMA | Director | Dec 26, 2014 | Sale | $3.71 | 131,100 | 486,460 | 15,022,732 | Dec 30, 2014, 05:40 PM |
| XOMA | Director | Dec 18, 2014 | Sale | $4.29 | 165,700 | 710,687 | 15,783,368 | Dec 19, 2014, 05:13 PM |
| XOMA | Director | Dec 17, 2014 | Sale | $4.31 | 686,500 | 2,958,129 | 15,925,911 | Dec 19, 2014, 05:13 PM |
| XOMA | Director | Dec 19, 2014 | Sale | $4.21 | 752,900 | 3,168,580 | 15,135,587 | Dec 19, 2014, 05:13 PM |
| XOMA | Director | Dec 16, 2014 | Sale | $4.27 | 319,200 | 1,363,271 | 16,516,549 | Dec 16, 2014, 05:29 PM |
| XOMA | Director | Dec 15, 2014 | Sale | $4.45 | 460,800 | 2,050,652 | 16,791,283 | Dec 16, 2014, 05:29 PM |
| XOMA | Director | Dec 12, 2014 | Sale | $4.71 | 253,800 | 1,196,413 | 17,187,779 | Dec 16, 2014, 05:29 PM |
| SGEN | Director | Dec 09, 2014 | Buy | $34.16 | 128,430 | 4,387,345 | 20,455,616 | Dec 10, 2014, 08:04 PM |
| SGEN | Director | Dec 08, 2014 | Buy | $32.93 | 465,316 | 15,320,685 | 20,327,186 | Dec 10, 2014, 08:04 PM |
| SGEN | Director | Dec 10, 2014 | Buy | $34.40 | 654,150 | 22,501,700 | 21,109,766 | Dec 10, 2014, 08:04 PM |
| XOMA | Director | Dec 09, 2014 | Sale | $4.62 | 392,353 | 1,811,062 | 17,406,162 | Dec 10, 2014, 05:50 PM |
| XOMA | Director | Dec 04, 2014 | Sale | $4.55 | 1,304,288 | 5,928,902 | 17,743,703 | Dec 04, 2014, 06:05 PM |
| XOMA | Director | Dec 03, 2014 | Sale | $4.84 | 567,918 | 2,748,837 | 18,866,287 | Dec 04, 2014, 06:05 PM |
| XOMA | Director | Dec 02, 2014 | Sale | $5.36 | 500,000 | 2,679,550 | 19,353,087 | Dec 04, 2014, 06:05 PM |
| IDRA | Director | Oct 01, 2014 | Option Exercise | $2.16 | 26,742 | 57,763 | 1,421,519 | Oct 03, 2014, 05:55 PM |
| GHDX | Director | Jul 01, 2014 | Option Exercise | $27.86 | 4,296 | 119,687 | 11,245,068 | Jul 03, 2014, 02:33 PM |
| IDRA | Director | Jul 01, 2014 | Option Exercise | $2.83 | 18,546 | 52,485 | 1,412,605 | Jul 03, 2014, 02:32 PM |
| GEVA | Director | Jun 20, 2014 | Option Exercise | $60.45 | 29,750 | 1,798,388 | 8,184,771 | Jun 24, 2014, 04:12 PM |
| SGEN | Director | Jun 13, 2014 | Buy | $39.89 | 88,587 | 3,533,526 | 18,207,945 | Jun 16, 2014, 04:33 PM |
| SGEN | Director | Jun 12, 2014 | Buy | $39.94 | 128,008 | 5,112,199 | 18,121,499 | Jun 16, 2014, 04:33 PM |
| SGEN | Director | Jun 09, 2014 | Buy | $38.92 | 251,093 | 9,772,651 | 17,996,584 | Jun 09, 2014, 05:26 PM |
| SGEN | Director | Jun 06, 2014 | Buy | $37.41 | 174,987 | 6,546,471 | 17,751,559 | Jun 09, 2014, 05:26 PM |
| SGEN | Director | Jun 05, 2014 | Buy | $37.67 | 120,172 | 4,526,317 | 17,580,806 | Jun 09, 2014, 05:26 PM |
| SGEN | Director | Jun 04, 2014 | Buy | $36.13 | 87,042 | 3,145,161 | 17,463,541 | Jun 04, 2014, 07:27 PM |
| SGEN | Director | Jun 03, 2014 | Buy | $34.47 | 100,304 | 3,457,722 | 17,378,605 | Jun 04, 2014, 07:27 PM |
| SGEN | Director | Jun 02, 2014 | Buy | $34.09 | 94,617 | 3,225,210 | 17,280,727 | Jun 04, 2014, 07:27 PM |
| INCY | Director | May 21, 2014 | Option Exercise | $7.02 | 30,000 | 210,600 | 12,465,783 | May 23, 2014, 05:07 PM |
| SGEN | Director | May 14, 2014 | Option Exercise | $7.26 | 30,000 | 217,800 | 16,999,872 | May 16, 2014, 07:00 PM |
| SGEN | Director | May 16, 2014 | Buy | $34.05 | 168,411 | 5,734,196 | 17,188,399 | May 16, 2014, 07:00 PM |
| SGEN | Director | May 15, 2014 | Buy | $34.26 | 21,200 | 726,356 | 17,020,560 | May 16, 2014, 07:00 PM |
| SGEN | Director | May 09, 2014 | Buy | $34.16 | 138,073 | 4,715,922 | 16,989,872 | May 16, 2014, 04:52 PM |
| SGEN | Director | May 08, 2014 | Buy | $34.02 | 233,055 | 7,929,305 | 16,855,137 | May 16, 2014, 04:52 PM |
| SGEN | Director | May 07, 2014 | Buy | $33.59 | 117,254 | 3,938,140 | 16,627,717 | May 16, 2014, 04:52 PM |
| SGEN | Director | May 07, 2013 | Buy | $33.59 | 117,254 | 3,938,140 | 16,627,717 | May 09, 2014, 05:16 PM |
| SGEN | Director | May 09, 2013 | Buy | $34.16 | 138,073 | 4,715,922 | 16,989,872 | May 09, 2014, 05:16 PM |
| SGEN | Director | May 08, 2013 | Buy | $34.02 | 233,055 | 7,929,305 | 16,855,137 | May 09, 2014, 05:16 PM |
| GEVA | Director | Apr 23, 2014 | Option Exercise | $65.10 | 56,000 | 3,645,600 | 8,180,521 | Apr 25, 2014, 08:04 PM |
| GHDX | Director | Apr 01, 2014 | Option Exercise | $26.57 | 4,512 | 119,884 | 11,244,352 | Apr 03, 2014, 07:22 PM |
| GEVA | Director | Mar 06, 2014 | Buy | $105.75 | 375,000 | 39,656,250 | 8,172,521 | Mar 07, 2014, 05:54 PM |
| ACAD | Director | Mar 05, 2014 | Buy | $28.50 | 526,316 | 15,000,006 | 18,476,847 | Mar 07, 2014, 05:27 PM |
| GHDX | Director | Jan 01, 2014 | Option Exercise | $29.27 | 4,092 | 119,773 | 11,243,600 | Jan 03, 2014, 05:29 PM |
| SGEN | Director | Dec 13, 2013 | Buy | $39.65 | 43,709 | 1,733,276 | 16,436,458 | Dec 16, 2013, 07:42 PM |
| SGEN | Director | Dec 12, 2013 | Buy | $39.59 | 284,610 | 11,268,201 | 16,393,812 | Dec 16, 2013, 07:42 PM |
| SGEN | Director | Dec 16, 2013 | Buy | $39.92 | 78,759 | 3,143,952 | 16,513,298 | Dec 16, 2013, 07:42 PM |
| SGEN | Director | Dec 05, 2013 | Buy | $44.00 | 365,676 | 16,089,489 | 16,116,121 | Dec 05, 2013, 08:13 PM |
| SGEN | Director | Dec 04, 2013 | Buy | $43.11 | 270,795 | 11,675,184 | 15,759,353 | Dec 05, 2013, 08:13 PM |
| SGEN | Director | Dec 03, 2013 | Buy | $42.44 | 369,430 | 15,678,059 | 15,495,154 | Dec 05, 2013, 08:13 PM |
| MRTX | 10% Owner | Oct 24, 2013 | Buy | $17.50 | 400,000 | 7,000,000 | 2,213,897 | Oct 28, 2013, 08:15 PM |
| GHDX | Director | Oct 01, 2013 | Option Exercise | $30.33 | 3,948 | 119,743 | 11,242,918 | Oct 02, 2013, 05:27 PM |
| GEVA | Director | Sep 25, 2013 | Buy | $56.63 | 1,050,000 | 59,461,501 | 7,806,552 | Sep 27, 2013, 04:08 PM |
| XOMA | Director | Aug 19, 2013 | Buy | $3.62 | 2,757,791 | 9,983,203 | 19,767,770 | Aug 21, 2013, 07:54 PM |
| XOMA | Director | Aug 19, 2013 | Option Exercise | $3.62 | 2,757,791 | 9,983,203 | 19,767,770 | Aug 21, 2013, 05:07 PM |
| BCRX | 10% Owner | Aug 01, 2013 | Buy | $4.40 | 1,136,364 | 5,000,002 | 4,832,285 | Aug 02, 2013, 04:00 PM |
| GHDX | Director | Jul 01, 2013 | Option Exercise | $32.85 | 3,636 | 119,443 | 11,242,260 | Jul 03, 2013, 05:25 PM |
| INCY | Director | Jun 11, 2013 | Option Exercise | $4.44 | 30,000 | 133,200 | 12,455,783 | Jun 13, 2013, 06:49 PM |
| ACAD | Director | Jun 04, 2013 | Buy | $14.45 | 699,776 | 10,110,693 | 17,240,358 | Jun 05, 2013, 06:47 PM |
| ACAD | Director | Jun 03, 2013 | Buy | $14.06 | 767,953 | 10,794,614 | 16,630,193 | Jun 05, 2013, 06:47 PM |
| ACAD | Director | Jun 05, 2013 | Buy | $14.51 | 872,585 | 12,657,999 | 18,001,203 | Jun 05, 2013, 06:47 PM |
| GHDX | Director | Jun 05, 2013 | Buy | $35.81 | 194,621 | 6,970,351 | 11,241,654 | Jun 05, 2013, 05:23 PM |
| GHDX | Director | Jun 05, 2013 | Buy | $35.81 | 23,152 | 829,189 | 1,730,777 | Jun 05, 2013, 05:23 PM |
| GHDX | Director | Jun 04, 2013 | Buy | $36.62 | 163,659 | 5,993,192 | 11,051,768 | Jun 05, 2013, 05:23 PM |
| GHDX | Director | May 29, 2013 | Buy | $36.82 | 5,046 | 185,802 | 1,671,081 | May 29, 2013, 06:06 PM |
| GHDX | Director | May 28, 2013 | Buy | $36.93 | 74,266 | 2,742,933 | 10,711,599 | May 29, 2013, 06:06 PM |
| GHDX | Director | May 29, 2013 | Buy | $36.82 | 41,954 | 1,544,813 | 10,752,532 | May 29, 2013, 06:06 PM |
| GHDX | Director | May 24, 2013 | Buy | $36.93 | 62,517 | 2,308,909 | 10,646,920 | May 24, 2013, 05:04 PM |
| GHDX | Director | May 23, 2013 | Buy | $36.99 | 13,645 | 504,693 | 10,592,521 | May 24, 2013, 05:04 PM |
| GHDX | Director | May 23, 2013 | Buy | $36.59 | 3,255 | 119,106 | 10,579,208 | May 24, 2013, 05:04 PM |
| ACAD | Director | May 15, 2013 | Buy | $12.50 | 1,993,000 | 24,912,500 | 15,960,582 | May 17, 2013, 04:10 PM |
| GHDX | Director | May 16, 2013 | Buy | $36.54 | 17,186 | 627,963 | 10,577,816 | May 16, 2013, 06:03 PM |
| GHDX | Director | May 16, 2013 | Buy | $36.54 | 2,120 | 77,463 | 1,649,473 | May 16, 2013, 06:03 PM |
| GHDX | Director | May 15, 2013 | Buy | $36.41 | 52,133 | 1,898,361 | 10,561,048 | May 16, 2013, 06:03 PM |
| GHDX | Director | May 14, 2013 | Buy | $35.53 | 27,184 | 965,899 | 10,515,769 | May 14, 2013, 06:40 PM |
| GHDX | Director | May 13, 2013 | Buy | $34.02 | 144,478 | 4,914,910 | 10,492,159 | May 14, 2013, 06:40 PM |
| GHDX | Director | May 13, 2013 | Buy | $34.56 | 68,764 | 2,376,256 | 10,351,197 | May 14, 2013, 06:40 PM |
| GHDX | Director | Apr 01, 2013 | Option Exercise | $27.99 | 4,284 | 119,909 | 10,306,953 | Apr 03, 2013, 05:50 PM |
| GHDX | Director | Feb 21, 2013 | Buy | $27.64 | 25,120 | 694,237 | 10,306,239 | Feb 21, 2013, 06:11 PM |
| GHDX | Director | Feb 21, 2013 | Buy | $27.64 | 3,080 | 85,122 | 1,614,513 | Feb 21, 2013, 06:11 PM |
| GHDX | Director | Feb 20, 2013 | Buy | $27.97 | 20,885 | 584,220 | 10,281,731 | Feb 21, 2013, 06:11 PM |
| GHDX | Director | Feb 14, 2013 | Buy | $28.43 | 30,860 | 877,384 | 10,263,580 | Feb 14, 2013, 05:51 PM |
| GHDX | Director | Feb 14, 2013 | Buy | $28.43 | 3,940 | 112,019 | 1,609,152 | Feb 14, 2013, 05:51 PM |
| GHDX | Director | Feb 13, 2013 | Buy | $28.58 | 17,200 | 491,585 | 10,233,478 | Feb 14, 2013, 05:51 PM |
| GHDX | Director | Feb 11, 2013 | Buy | $28.23 | 9,055 | 255,638 | 1,603,265 | Feb 11, 2013, 06:43 PM |
| GHDX | Director | Feb 08, 2013 | Buy | $27.96 | 36,376 | 1,017,106 | 10,149,413 | Feb 11, 2013, 06:43 PM |
| GHDX | Director | Feb 11, 2013 | Buy | $28.23 | 70,929 | 2,002,446 | 10,218,600 | Feb 11, 2013, 06:43 PM |
| GEVA | Director | Jan 04, 2013 | Buy | $47.53 | 859,720 | 40,862,491 | 6,782,215 | Jan 08, 2013, 05:40 PM |
| GHDX | Director | Nov 21, 2012 | Buy | $27.54 | 300 | 8,262 | 10,117,174 | Nov 23, 2012, 01:24 PM |
| GHDX | Director | Nov 20, 2012 | Buy | $26.83 | 229,000 | 6,143,360 | 10,116,906 | Nov 23, 2012, 01:24 PM |
| XOMA | Director | Oct 29, 2012 | Buy | $3.00 | 4,722,666 | 14,167,998 | 17,888,512 | Oct 31, 2012, 05:02 PM |
| INCY | Director | Aug 01, 2012 | Option Exercise | $5.67 | 10,000 | 56,700 | 66,340 | Aug 03, 2012, 05:35 PM |
| GEVA | Director | Jul 13, 2012 | Buy | $41.20 | 886,000 | 36,503,201 | 5,942,594 | Jul 13, 2012, 06:59 PM |
| RDEA | Director | Jun 19, 2012 | Option Exercise | $32.00 | 6,914,291 | 221,257,312 | 0 | Jun 21, 2012, 04:13 PM |
| INCY | Director | Jun 04, 2012 | Option Exercise | $6.66 | 5,000 | 33,300 | 5,000 | Jun 06, 2012, 04:55 PM |
| GHDX | Director | May 22, 2012 | Buy | $32.94 | 17,406 | 573,401 | 9,086,690 | May 23, 2012, 05:03 PM |
| GHDX | Director | May 21, 2012 | Buy | $32.18 | 150,000 | 4,826,972 | 9,069,664 | May 23, 2012, 05:03 PM |
| GHDX | Director | May 14, 2012 | Buy | $33.68 | 212,438 | 7,153,896 | 8,762,905 | May 16, 2012, 08:18 PM |
| GHDX | Director | May 16, 2012 | Buy | $34.46 | 23,621 | 813,925 | 8,922,942 | May 16, 2012, 08:18 PM |
| GHDX | Director | May 15, 2012 | Buy | $34.09 | 140,000 | 4,772,474 | 8,899,838 | May 16, 2012, 08:18 PM |
| GHDX | Director | May 11, 2012 | Buy | $30.22 | 26,660 | 805,567 | 8,555,121 | May 11, 2012, 06:01 PM |
| GHDX | Director | May 10, 2012 | Buy | $29.87 | 68,681 | 2,051,783 | 8,529,088 | May 11, 2012, 06:01 PM |
| GHDX | Director | May 09, 2012 | Buy | $29.90 | 19,547 | 584,367 | 8,462,023 | May 11, 2012, 06:01 PM |
| GHDX | Director | May 04, 2012 | Buy | $28.02 | 53,128 | 1,488,643 | 8,305,414 | May 08, 2012, 07:00 PM |
| GHDX | Director | May 08, 2012 | Buy | $28.83 | 86,033 | 2,480,619 | 8,442,936 | May 08, 2012, 07:00 PM |
| GHDX | Director | May 07, 2012 | Buy | $28.26 | 56,540 | 1,597,965 | 8,358,928 | May 08, 2012, 07:00 PM |
| TZYM | 10% Owner | Mar 14, 2012 | Buy | $3.00 | 90,838 | 272,090 | 3,540,015 | Mar 14, 2012, 05:37 PM |
| TZYM | 10% Owner | Mar 13, 2012 | Buy | $2.96 | 159,015 | 470,382 | 3,449,177 | Mar 14, 2012, 05:37 PM |
| TZYM | 10% Owner | Mar 12, 2012 | Buy | $2.44 | 961,299 | 2,341,269 | 3,290,162 | Mar 14, 2012, 05:37 PM |
| TZYM | 10% Owner | Mar 14, 2012 | Buy | $3.00 | 2,392 | 7,165 | 57,704 | Mar 14, 2012, 05:34 PM |
| TZYM | 10% Owner | Mar 13, 2012 | Buy | $2.96 | 4,186 | 12,383 | 55,312 | Mar 14, 2012, 05:34 PM |
| TZYM | 10% Owner | Mar 12, 2012 | Buy | $2.44 | 25,304 | 61,629 | 51,126 | Mar 14, 2012, 05:34 PM |
| GHDX | Director | Mar 08, 2012 | Buy | $30.36 | 2,162 | 65,647 | 1,484,977 | Mar 09, 2012, 06:28 PM |
| GHDX | Director | Mar 07, 2012 | Buy | $29.88 | 2,346 | 70,097 | 1,482,815 | Mar 09, 2012, 06:28 PM |
| GHDX | Director | Mar 08, 2012 | Buy | $30.36 | 516 | 15,668 | 227,840 | Mar 09, 2012, 06:28 PM |
| GHDX | Director | Mar 07, 2012 | Buy | $29.88 | 583 | 17,420 | 227,324 | Mar 09, 2012, 06:28 PM |
| GHDX | Director | Mar 08, 2012 | Buy | $30.36 | 19,513 | 592,489 | 8,255,421 | Mar 09, 2012, 06:27 PM |
| GHDX | Director | Mar 07, 2012 | Buy | $29.88 | 22,071 | 659,464 | 8,235,908 | Mar 09, 2012, 06:27 PM |
| GHDX | Director | Mar 05, 2012 | Buy | $30.01 | 155,014 | 4,651,479 | 8,213,837 | Mar 05, 2012, 06:28 PM |
| GHDX | Director | Mar 02, 2012 | Buy | $29.52 | 91,459 | 2,699,915 | 8,058,823 | Mar 05, 2012, 06:28 PM |
| GHDX | Director | Mar 01, 2012 | Buy | $29.47 | 15,288 | 450,543 | 7,967,364 | Mar 05, 2012, 06:28 PM |
| GHDX | Director | Mar 05, 2012 | Buy | $30.01 | 18,597 | 558,037 | 1,480,469 | Mar 05, 2012, 06:26 PM |
| GHDX | Director | Mar 02, 2012 | Buy | $29.52 | 10,972 | 323,899 | 1,461,872 | Mar 05, 2012, 06:26 PM |
| GHDX | Director | Mar 01, 2012 | Buy | $29.47 | 1,763 | 51,956 | 1,450,900 | Mar 05, 2012, 06:26 PM |
| GHDX | Director | Feb 29, 2012 | Buy | $29.06 | 4,149 | 120,562 | 219,818 | Feb 29, 2012, 05:42 PM |
| GHDX | Director | Feb 28, 2012 | Buy | $29.11 | 1,353 | 39,384 | 215,669 | Feb 29, 2012, 05:42 PM |
| GHDX | Director | Feb 27, 2012 | Buy | $29.03 | 974 | 28,276 | 214,316 | Feb 29, 2012, 05:42 PM |
| GHDX | Director | Feb 29, 2012 | Buy | $29.06 | 156,902 | 4,559,274 | 7,952,076 | Feb 29, 2012, 05:41 PM |
| GHDX | Director | Feb 28, 2012 | Buy | $29.11 | 51,248 | 1,491,752 | 7,795,174 | Feb 29, 2012, 05:41 PM |
| GHDX | Director | Feb 27, 2012 | Buy | $29.03 | 36,881 | 1,070,678 | 7,743,926 | Feb 29, 2012, 05:41 PM |
| GHDX | Director | Feb 28, 2012 | Buy | $29.11 | 5,934 | 172,730 | 1,429,585 | Feb 29, 2012, 05:39 PM |
| GHDX | Director | Feb 27, 2012 | Buy | $29.03 | 4,270 | 123,961 | 1,423,651 | Feb 29, 2012, 05:39 PM |
| GHDX | Director | Feb 29, 2012 | Buy | $29.06 | 19,552 | 568,144 | 1,449,137 | Feb 29, 2012, 05:39 PM |
| GHDX | Director | Feb 23, 2012 | Buy | $28.12 | 1,639 | 46,095 | 213,342 | Feb 23, 2012, 06:08 PM |
| GHDX | Director | Feb 22, 2012 | Buy | $27.98 | 145 | 4,057 | 211,703 | Feb 23, 2012, 06:08 PM |
| GHDX | Director | Feb 21, 2012 | Buy | $27.98 | 1,238 | 34,635 | 211,558 | Feb 23, 2012, 06:08 PM |
| GHDX | Director | Feb 22, 2012 | Buy | $27.98 | 638 | 17,852 | 1,411,904 | Feb 23, 2012, 06:08 PM |
| GHDX | Director | Feb 21, 2012 | Buy | $27.98 | 5,217 | 145,955 | 1,411,266 | Feb 23, 2012, 06:08 PM |
| GHDX | Director | Feb 23, 2012 | Buy | $28.12 | 7,477 | 210,282 | 1,419,381 | Feb 23, 2012, 06:08 PM |
| GHDX | Director | Feb 16, 2012 | Buy | $29.73 | 21,900 | 651,092 | 1,406,049 | Feb 16, 2012, 06:58 PM |
| GHDX | Director | Feb 15, 2012 | Buy | $28.88 | 3,944 | 113,892 | 1,384,149 | Feb 16, 2012, 06:58 PM |
| GHDX | Director | Feb 14, 2012 | Buy | $28.44 | 7,341 | 208,756 | 1,380,205 | Feb 16, 2012, 06:58 PM |
| PCYC | 10% Owner | Feb 10, 2012 | Buy | $20.85 | 150,000 | 3,128,040 | 557,211 | Feb 14, 2012, 05:53 PM |
| GHDX | Director | Feb 09, 2012 | Buy | $26.32 | 55,994 | 1,473,628 | 7,159,786 | Feb 10, 2012, 09:34 PM |
| GHDX | Director | Feb 08, 2012 | Buy | $26.20 | 202,089 | 5,294,563 | 7,103,792 | Feb 10, 2012, 09:34 PM |
| GHDX | Director | Feb 10, 2012 | Buy | $26.59 | 159,832 | 4,249,931 | 7,319,618 | Feb 10, 2012, 09:34 PM |
| GHDX | Director | Feb 10, 2012 | Buy | $26.59 | 4,225 | 112,343 | 203,107 | Feb 10, 2012, 09:33 PM |
| GHDX | Director | Feb 09, 2012 | Buy | $26.32 | 1,478 | 38,898 | 198,882 | Feb 10, 2012, 09:33 PM |
| GHDX | Director | Feb 08, 2012 | Buy | $26.20 | 5,340 | 139,904 | 197,404 | Feb 10, 2012, 09:33 PM |
| GHDX | Director | Feb 08, 2012 | Buy | $26.20 | 33,141 | 868,267 | 1,339,422 | Feb 10, 2012, 09:33 PM |
| GHDX | Director | Feb 10, 2012 | Buy | $26.59 | 24,582 | 653,635 | 1,372,864 | Feb 10, 2012, 09:33 PM |
| GHDX | Director | Feb 09, 2012 | Buy | $26.32 | 8,860 | 233,174 | 1,348,282 | Feb 10, 2012, 09:33 PM |
| RDEA | Director | Feb 01, 2012 | Buy | $17.00 | 876,828 | 14,906,076 | 4,922,226 | Feb 03, 2012, 05:52 PM |
| RDEA | Director | Feb 01, 2012 | Buy | $17.00 | 23,172 | 393,924 | 116,454 | Feb 03, 2012, 05:51 PM |
| DDXS | 10% Owner | Jan 27, 2012 | Sale | $0.22 | 59,340 | 13,156 | 0 | Jan 31, 2012, 07:15 PM |
| PCYC | 10% Owner | Jan 24, 2012 | Buy | $17.95 | 22,555 | 404,958 | 343,773 | Jan 26, 2012, 06:12 PM |
| PCYC | 10% Owner | Jan 26, 2012 | Buy | $17.93 | 41,873 | 750,902 | 407,211 | Jan 26, 2012, 06:12 PM |
| PCYC | 10% Owner | Jan 25, 2012 | Buy | $18.53 | 21,565 | 399,626 | 365,338 | Jan 26, 2012, 06:12 PM |
| PCYC | 10% Owner | Jan 26, 2012 | Buy | $17.93 | 6,304 | 113,049 | 195,858 | Jan 26, 2012, 06:09 PM |
| PCYC | 10% Owner | Jan 25, 2012 | Buy | $18.53 | 3,246 | 60,152 | 189,554 | Jan 26, 2012, 06:09 PM |
| PCYC | 10% Owner | Jan 24, 2012 | Buy | $17.95 | 3,395 | 60,955 | 186,308 | Jan 26, 2012, 06:09 PM |
| PCYC | 10% Owner | Jan 19, 2012 | Buy | $16.05 | 938 | 15,055 | 171,404 | Jan 23, 2012, 08:40 PM |
| PCYC | 10% Owner | Jan 23, 2012 | Buy | $16.87 | 4,273 | 72,097 | 182,913 | Jan 23, 2012, 08:40 PM |
| PCYC | 10% Owner | Jan 20, 2012 | Buy | $16.42 | 6,536 | 107,306 | 177,940 | Jan 23, 2012, 08:40 PM |
| PCYC | 10% Owner | Jan 20, 2012 | Option Exercise | $15.00 | 700 | 10,500 | 178,640 | Jan 23, 2012, 08:40 PM |
| PCYC | 10% Owner | Jan 23, 2012 | Buy | $16.87 | 162,215 | 2,737,009 | 8,073,793 | Jan 23, 2012, 08:40 PM |
| PCYC | 10% Owner | Jan 20, 2012 | Buy | $16.42 | 248,166 | 4,073,980 | 7,886,678 | Jan 23, 2012, 08:40 PM |
| PCYC | 10% Owner | Jan 19, 2012 | Buy | $16.05 | 34,857 | 559,459 | 7,638,512 | Jan 23, 2012, 08:40 PM |
| PCYC | 10% Owner | Jan 20, 2012 | Option Exercise | $15.00 | 24,900 | 373,500 | 7,911,578 | Jan 23, 2012, 08:40 PM |
| PCYC | 10% Owner | Jan 20, 2012 | Buy | $16.42 | 43,156 | 708,524 | 288,609 | Jan 23, 2012, 08:39 PM |
| PCYC | 10% Owner | Jan 19, 2012 | Buy | $16.05 | 6,060 | 97,264 | 245,453 | Jan 23, 2012, 08:39 PM |
| PCYC | 10% Owner | Jan 23, 2012 | Buy | $16.87 | 28,209 | 475,963 | 321,218 | Jan 23, 2012, 08:39 PM |
| PCYC | 10% Owner | Jan 20, 2012 | Option Exercise | $15.00 | 4,400 | 66,000 | 293,009 | Jan 23, 2012, 08:39 PM |
| DDXS | 10% Owner | Jan 19, 2012 | Sale | $0.20 | 20,000 | 4,000 | 59,340 | Jan 20, 2012, 06:18 PM |
| DDXS | 10% Owner | Jan 18, 2012 | Sale | $0.21 | 118,800 | 25,233 | 79,340 | Jan 20, 2012, 06:18 PM |
| INCY | Director | Jan 12, 2012 | Buy | $16.26 | 8,769 | 142,615 | 349,983 | Jan 17, 2012, 08:43 PM |
| INCY | Director | Jan 13, 2012 | Buy | $16.53 | 5,856 | 96,794 | 355,839 | Jan 17, 2012, 08:43 PM |
| INCY | Director | Jan 13, 2012 | Buy | $16.53 | 217,511 | 3,595,234 | 12,430,783 | Jan 17, 2012, 08:43 PM |
| INCY | Director | Jan 12, 2012 | Buy | $16.26 | 325,728 | 5,297,473 | 12,213,272 | Jan 17, 2012, 08:43 PM |
| GEVA | Director | Jan 05, 2012 | Option Exercise | $25.18 | 1,077,225 | 27,124,526 | 5,077,676 | Jan 09, 2012, 07:01 PM |
| GEVA | Director | Jan 05, 2012 | Option Exercise | $25.18 | 29,089 | 732,461 | 135,739 | Jan 09, 2012, 07:00 PM |
| GEVA | Director | Jan 05, 2012 | Option Exercise | $25.18 | 187,576 | 4,723,164 | 1,736,065 | Jan 09, 2012, 07:00 PM |
| SGEN | Director | Dec 30, 2011 | Option Exercise | $6.25 | 355,143 | 2,219,644 | 15,131,223 | Jan 04, 2012, 07:25 PM |
| SGEN | Director | Dec 30, 2011 | Option Exercise | $6.25 | 68,006 | 425,038 | 539,130 | Jan 04, 2012, 07:24 PM |
| SGEN | Director | Dec 30, 2011 | Option Exercise | $6.25 | 339,788 | 2,123,675 | 4,966,001 | Jan 04, 2012, 07:24 PM |
| SGEN | Director | Dec 30, 2011 | Option Exercise | $6.25 | 49,563 | 309,769 | 450,461 | Jan 04, 2012, 07:23 PM |
| ADLR | 10% Owner | Dec 19, 2011 | Option Exercise | $4.25 | 12,679 | 53,886 | 0 | Jan 03, 2012, 06:04 PM |
| ADLR | 10% Owner | Dec 19, 2011 | Option Exercise | $4.25 | 186,272 | 791,656 | 0 | Jan 03, 2012, 06:04 PM |
| ADLR | 10% Owner | Dec 19, 2011 | Option Exercise | $4.25 | 79,054 | 335,980 | 0 | Jan 03, 2012, 06:01 PM |
| INCY | Director | Dec 09, 2011 | Buy | $13.26 | 181,201 | 2,402,409 | 11,887,544 | Dec 12, 2011, 05:23 PM |
| INCY | Director | Dec 08, 2011 | Buy | $13.46 | 222,320 | 2,992,186 | 11,706,343 | Dec 12, 2011, 05:23 PM |
| INCY | Director | Dec 09, 2011 | Buy | $13.26 | 4,862 | 64,462 | 341,214 | Dec 12, 2011, 05:22 PM |
| INCY | Director | Dec 08, 2011 | Buy | $13.46 | 5,965 | 80,282 | 336,352 | Dec 12, 2011, 05:22 PM |
| INCY | Director | Dec 07, 2011 | Buy | $13.22 | 3,878 | 51,256 | 330,387 | Dec 07, 2011, 05:58 PM |
| INCY | Director | Dec 06, 2011 | Buy | $13.53 | 9,057 | 122,526 | 326,509 | Dec 07, 2011, 05:58 PM |
| INCY | Director | Dec 05, 2011 | Buy | $13.89 | 28,685 | 398,315 | 317,452 | Dec 07, 2011, 05:58 PM |
| INCY | Director | Dec 07, 2011 | Buy | $13.22 | 144,903 | 1,915,214 | 11,484,023 | Dec 07, 2011, 05:57 PM |
| INCY | Director | Dec 06, 2011 | Buy | $13.53 | 338,406 | 4,578,060 | 11,339,120 | Dec 07, 2011, 05:57 PM |
| INCY | Director | Dec 05, 2011 | Buy | $13.89 | 1,071,825 | 14,883,177 | 11,000,714 | Dec 07, 2011, 05:57 PM |
| PCYC | 10% Owner | Dec 02, 2011 | Buy | $15.42 | 14,561 | 224,467 | 239,393 | Dec 06, 2011, 06:12 PM |
| PCYC | 10% Owner | Dec 02, 2011 | Buy | $15.42 | 88,197 | 1,359,615 | 7,603,655 | Dec 06, 2011, 06:09 PM |
| PCYC | 10% Owner | Dec 02, 2011 | Buy | $15.42 | 2,360 | 36,381 | 170,466 | Dec 06, 2011, 06:08 PM |
| GHDX | Director | Dec 05, 2011 | Buy | $28.45 | 548 | 15,593 | 192,064 | Dec 05, 2011, 06:19 PM |
| GHDX | Director | Dec 02, 2011 | Buy | $28.05 | 2,604 | 73,045 | 191,516 | Dec 05, 2011, 06:19 PM |
| GHDX | Director | Dec 05, 2011 | Buy | $28.45 | 3,377 | 96,092 | 1,306,281 | Dec 05, 2011, 06:18 PM |
| GHDX | Director | Dec 02, 2011 | Buy | $28.05 | 16,063 | 450,585 | 1,302,904 | Dec 05, 2011, 06:18 PM |
| GHDX | Director | Dec 01, 2011 | Buy | $27.33 | 26,537 | 725,256 | 1,286,841 | Dec 05, 2011, 06:18 PM |
| GHDX | Director | Dec 02, 2011 | Buy | $28.05 | 97,295 | 2,729,234 | 6,881,247 | Dec 05, 2011, 06:16 PM |
| GHDX | Director | Dec 05, 2011 | Buy | $28.45 | 20,456 | 582,072 | 6,901,703 | Dec 05, 2011, 06:16 PM |
| INCY | Director | Dec 01, 2011 | Buy | $14.12 | 22,380 | 315,958 | 288,767 | Dec 01, 2011, 04:33 PM |
| INCY | Director | Nov 29, 2011 | Buy | $12.21 | 28,890 | 352,819 | 266,387 | Dec 01, 2011, 04:33 PM |
| INCY | Director | Dec 01, 2011 | Buy | $14.12 | 828,622 | 11,698,369 | 9,928,889 | Dec 01, 2011, 04:31 PM |
| INCY | Director | Nov 30, 2011 | Buy | $13.44 | 507,911 | 6,826,897 | 9,100,267 | Dec 01, 2011, 04:31 PM |
| INCY | Director | Nov 29, 2011 | Buy | $12.21 | 1,069,646 | 13,063,037 | 8,592,356 | Dec 01, 2011, 04:31 PM |
| PCYC | 10% Owner | Nov 29, 2011 | Buy | $14.18 | 4,383 | 62,133 | 168,106 | Nov 30, 2011, 06:20 PM |
| PCYC | 10% Owner | Nov 28, 2011 | Buy | $13.34 | 4,052 | 54,055 | 163,723 | Nov 30, 2011, 06:20 PM |
| PCYC | 10% Owner | Nov 28, 2011 | Buy | $13.34 | 25,764 | 343,702 | 185,797 | Nov 30, 2011, 06:19 PM |
| PCYC | 10% Owner | Nov 30, 2011 | Buy | $14.92 | 11,164 | 166,590 | 224,832 | Nov 30, 2011, 06:19 PM |
| PCYC | 10% Owner | Nov 29, 2011 | Buy | $14.18 | 27,871 | 395,097 | 213,668 | Nov 30, 2011, 06:19 PM |
| PCYC | 10% Owner | Nov 30, 2011 | Buy | $14.92 | 65,002 | 969,966 | 7,515,458 | Nov 30, 2011, 06:19 PM |
| PCYC | 10% Owner | Nov 29, 2011 | Buy | $14.18 | 162,271 | 2,300,343 | 7,450,456 | Nov 30, 2011, 06:19 PM |
| PCYC | 10% Owner | Nov 28, 2011 | Buy | $13.34 | 150,007 | 2,001,154 | 7,288,185 | Nov 30, 2011, 06:19 PM |
| GHDX | Director | Nov 23, 2011 | Buy | $25.83 | 539 | 13,923 | 188,912 | Nov 23, 2011, 05:00 PM |
| GHDX | Director | Nov 22, 2011 | Buy | $26.03 | 2,044 | 53,206 | 188,373 | Nov 23, 2011, 05:00 PM |
| GHDX | Director | Nov 21, 2011 | Buy | $25.91 | 3,167 | 82,041 | 186,329 | Nov 23, 2011, 05:00 PM |
| GHDX | Director | Nov 23, 2011 | Buy | $25.83 | 67,427 | 1,741,720 | 6,783,952 | Nov 23, 2011, 04:59 PM |
| GHDX | Director | Nov 22, 2011 | Buy | $26.03 | 46,328 | 1,205,927 | 6,716,525 | Nov 23, 2011, 04:59 PM |
| GHDX | Director | Nov 21, 2011 | Buy | $25.91 | 79,984 | 2,071,986 | 6,670,197 | Nov 23, 2011, 04:59 PM |
| GHDX | Director | Nov 23, 2011 | Buy | $25.83 | 2,273 | 58,714 | 1,260,304 | Nov 23, 2011, 04:59 PM |
| GHDX | Director | Nov 22, 2011 | Buy | $26.03 | 1,628 | 42,377 | 1,258,031 | Nov 23, 2011, 04:59 PM |
| GHDX | Director | Nov 21, 2011 | Buy | $25.91 | 1,630 | 42,225 | 1,256,403 | Nov 23, 2011, 04:59 PM |
| GHDX | Director | Nov 16, 2011 | Buy | $27.35 | 951 | 26,006 | 183,162 | Nov 17, 2011, 05:35 PM |
| GHDX | Director | Nov 15, 2011 | Buy | $27.93 | 1,599 | 44,666 | 182,211 | Nov 17, 2011, 05:35 PM |
| GHDX | Director | Nov 16, 2011 | Buy | $27.35 | 458 | 12,525 | 1,254,773 | Nov 17, 2011, 05:34 PM |
| GHDX | Director | Nov 11, 2011 | Buy | $27.66 | 4,052 | 112,088 | 179,045 | Nov 14, 2011, 06:13 PM |
| GHDX | Director | Nov 10, 2011 | Buy | $26.89 | 1,509 | 40,573 | 174,993 | Nov 14, 2011, 06:13 PM |
| GHDX | Director | Nov 09, 2011 | Buy | $26.79 | 2,978 | 79,778 | 173,484 | Nov 14, 2011, 06:13 PM |
| GHDX | Director | Nov 14, 2011 | Buy | $27.25 | 1,567 | 42,707 | 180,612 | Nov 14, 2011, 06:13 PM |
| GHDX | Director | Nov 09, 2011 | Buy | $26.79 | 72,479 | 1,941,654 | 6,348,720 | Nov 14, 2011, 06:13 PM |
| GHDX | Director | Nov 14, 2011 | Buy | $27.25 | 39,117 | 1,066,091 | 6,525,616 | Nov 14, 2011, 06:13 PM |
| GHDX | Director | Nov 11, 2011 | Buy | $27.66 | 100,823 | 2,789,006 | 6,486,499 | Nov 14, 2011, 06:13 PM |
| GHDX | Director | Nov 10, 2011 | Buy | $26.89 | 36,956 | 993,654 | 6,385,676 | Nov 14, 2011, 06:13 PM |
| GHDX | Director | Nov 09, 2011 | Buy | $26.79 | 542 | 14,520 | 1,254,315 | Nov 14, 2011, 05:17 PM |
| GHDX | Director | Nov 07, 2011 | Buy | $26.24 | 132,371 | 3,474,033 | 6,276,241 | Nov 07, 2011, 06:10 PM |
| GHDX | Director | Nov 04, 2011 | Buy | $25.78 | 55,920 | 1,441,461 | 6,143,870 | Nov 07, 2011, 06:10 PM |
| GHDX | Director | Nov 03, 2011 | Buy | $24.48 | 21,221 | 519,553 | 6,087,950 | Nov 07, 2011, 06:10 PM |
| GHDX | Director | Nov 03, 2011 | Buy | $24.48 | 898 | 21,986 | 162,557 | Nov 07, 2011, 06:10 PM |
| GHDX | Director | Nov 07, 2011 | Buy | $26.24 | 5,584 | 146,550 | 170,506 | Nov 07, 2011, 06:10 PM |
| GHDX | Director | Nov 04, 2011 | Buy | $25.78 | 2,365 | 60,963 | 164,922 | Nov 07, 2011, 06:10 PM |
| GHDX | Director | Nov 03, 2011 | Buy | $24.48 | 120 | 2,938 | 1,253,773 | Nov 07, 2011, 06:08 PM |
| VPHM | 10% Owner | Oct 05, 2011 | Buy | $18.18 | 16,278 | 295,984 | 1,915,524 | Oct 06, 2011, 05:36 PM |
| VPHM | 10% Owner | Oct 04, 2011 | Buy | $17.48 | 2,511 | 43,883 | 1,899,246 | Oct 06, 2011, 05:36 PM |
| VPHM | 10% Owner | Oct 05, 2011 | Buy | $18.18 | 145,763 | 2,650,423 | 9,548,763 | Oct 06, 2011, 05:35 PM |
| VPHM | 10% Owner | Oct 04, 2011 | Buy | $17.48 | 45,584 | 796,644 | 9,403,000 | Oct 06, 2011, 05:35 PM |
| VPHM | 10% Owner | Oct 05, 2011 | Buy | $18.18 | 6,017 | 109,408 | 295,436 | Oct 06, 2011, 05:34 PM |
| VPHM | 10% Owner | Oct 04, 2011 | Buy | $17.48 | 1,905 | 33,293 | 289,419 | Oct 06, 2011, 05:34 PM |
| VPHM | 10% Owner | Sep 30, 2011 | Buy | $18.12 | 5,012 | 90,801 | 287,514 | Oct 03, 2011, 06:43 PM |
| VPHM | 10% Owner | Sep 29, 2011 | Buy | $17.99 | 9,507 | 171,004 | 282,502 | Oct 03, 2011, 06:43 PM |
| VPHM | 10% Owner | Sep 29, 2011 | Buy | $17.99 | 249,915 | 4,495,274 | 8,709,235 | Oct 03, 2011, 06:42 PM |
| VPHM | 10% Owner | Oct 03, 2011 | Buy | $17.70 | 516,203 | 9,134,858 | 9,357,416 | Oct 03, 2011, 06:42 PM |
| VPHM | 10% Owner | Sep 30, 2011 | Buy | $18.12 | 131,978 | 2,391,014 | 8,841,213 | Oct 03, 2011, 06:42 PM |
| VPHM | 10% Owner | Sep 30, 2011 | Buy | $18.12 | 20,210 | 366,140 | 1,896,735 | Oct 03, 2011, 06:42 PM |
| VPHM | 10% Owner | Sep 29, 2011 | Buy | $17.99 | 32,995 | 593,488 | 1,876,525 | Oct 03, 2011, 06:42 PM |
| VPHM | 10% Owner | Sep 26, 2011 | Buy | $18.13 | 26,781 | 485,450 | 1,843,530 | Sep 26, 2011, 05:46 PM |
| VPHM | 10% Owner | Sep 23, 2011 | Buy | $17.74 | 36,728 | 651,492 | 1,816,749 | Sep 26, 2011, 05:46 PM |
| VPHM | 10% Owner | Sep 22, 2011 | Buy | $17.43 | 9,340 | 162,759 | 1,780,021 | Sep 26, 2011, 05:46 PM |
| VPHM | 10% Owner | Sep 23, 2011 | Buy | $17.74 | 224,769 | 3,987,016 | 8,299,679 | Sep 26, 2011, 05:40 PM |
| VPHM | 10% Owner | Sep 22, 2011 | Buy | $17.43 | 63,151 | 1,100,469 | 8,074,910 | Sep 26, 2011, 05:40 PM |
| VPHM | 10% Owner | Sep 26, 2011 | Buy | $18.13 | 159,641 | 2,893,756 | 8,459,320 | Sep 26, 2011, 05:40 PM |
| VPHM | 10% Owner | Sep 26, 2011 | Buy | $18.13 | 6,287 | 113,962 | 272,995 | Sep 26, 2011, 05:34 PM |
| VPHM | 10% Owner | Sep 23, 2011 | Buy | $17.74 | 8,933 | 158,456 | 266,708 | Sep 26, 2011, 05:34 PM |
| VPHM | 10% Owner | Sep 22, 2011 | Buy | $17.43 | 2,509 | 43,722 | 257,775 | Sep 26, 2011, 05:34 PM |
| SGEN | Director | Sep 06, 2011 | Buy | $17.08 | 1,773 | 30,285 | 323,148 | Sep 08, 2011, 05:13 PM |
| SGEN | Director | Sep 06, 2011 | Buy | $17.08 | 129,187 | 2,206,641 | 14,776,080 | Sep 08, 2011, 05:12 PM |
| SGEN | Director | Aug 25, 2011 | Buy | $15.49 | 984,850 | 15,253,844 | 14,646,893 | Aug 25, 2011, 05:37 PM |
| SGEN | Director | Aug 24, 2011 | Buy | $14.98 | 9,576 | 143,432 | 13,662,043 | Aug 25, 2011, 05:37 PM |
| SGEN | Director | Aug 23, 2011 | Buy | $14.79 | 171,009 | 2,528,388 | 13,652,467 | Aug 25, 2011, 05:37 PM |
| SGEN | Director | Aug 25, 2011 | Buy | $15.49 | 15,150 | 234,651 | 321,375 | Aug 25, 2011, 05:36 PM |
| SGEN | Director | Aug 24, 2011 | Buy | $14.98 | 147 | 2,202 | 306,225 | Aug 25, 2011, 05:36 PM |
| SGEN | Director | Aug 23, 2011 | Buy | $14.79 | 2,629 | 38,870 | 306,078 | Aug 25, 2011, 05:36 PM |
| VPHM | 10% Owner | Aug 23, 2011 | Buy | $16.97 | 5,468 | 92,814 | 1,770,681 | Aug 25, 2011, 05:19 PM |
| VPHM | 10% Owner | Aug 23, 2011 | Buy | $16.97 | 32,704 | 555,121 | 8,011,759 | Aug 25, 2011, 05:17 PM |
| VPHM | 10% Owner | Aug 23, 2011 | Buy | $16.97 | 503 | 8,538 | 255,266 | Aug 25, 2011, 05:13 PM |
| PCYC | 10% Owner | Aug 22, 2011 | Buy | $9.96 | 4,426 | 44,085 | 149,544 | Aug 24, 2011, 05:12 PM |
| PCYC | 10% Owner | Aug 22, 2011 | Buy | $9.96 | 287,264 | 2,861,270 | 6,813,790 | Aug 24, 2011, 05:11 PM |
| PCYC | 10% Owner | Aug 22, 2011 | Buy | $9.96 | 39,710 | 395,528 | 41,519 | Aug 24, 2011, 05:10 PM |
| AUXL | 10% Owner | Aug 01, 2011 | Sale | $18.04 | 8,145 | 146,896 | 72,731 | Aug 03, 2011, 04:53 PM |
| AUXL | 10% Owner | Aug 02, 2011 | Sale | $17.25 | 507 | 8,745 | 67,322 | Aug 03, 2011, 04:53 PM |
| GHDX | Director | Jun 09, 2011 | Buy | $26.26 | 89,891 | 2,360,109 | 6,059,449 | Jun 09, 2011, 05:34 PM |
| GHDX | Director | Jun 08, 2011 | Buy | $26.13 | 44,563 | 1,164,432 | 5,969,558 | Jun 09, 2011, 05:34 PM |
| GHDX | Director | Jun 07, 2011 | Buy | $26.16 | 69,198 | 1,810,136 | 5,924,995 | Jun 09, 2011, 05:34 PM |
| GHDX | Director | Jun 07, 2011 | Buy | $26.16 | 1,652 | 43,214 | 158,923 | Jun 09, 2011, 05:33 PM |
| GHDX | Director | Jun 09, 2011 | Buy | $26.26 | 1,671 | 43,873 | 161,659 | Jun 09, 2011, 05:33 PM |
| GHDX | Director | Jun 08, 2011 | Buy | $26.13 | 1,065 | 27,828 | 159,988 | Jun 09, 2011, 05:33 PM |
| GHDX | Director | Jun 09, 2011 | Buy | $26.25 | 49 | 1,286 | 194,415 | Jun 09, 2011, 05:32 PM |
| GHDX | Director | Jun 08, 2011 | Buy | $26.13 | 27 | 706 | 194,366 | Jun 09, 2011, 05:32 PM |
| GHDX | Director | Jun 07, 2011 | Buy | $26.16 | 43 | 1,125 | 194,339 | Jun 09, 2011, 05:32 PM |
| GHDX | Director | Jun 01, 2011 | Buy | $27.49 | 71,471 | 1,964,575 | 5,855,797 | Jun 01, 2011, 06:15 PM |
| GHDX | Director | May 31, 2011 | Buy | $27.48 | 55,039 | 1,512,235 | 5,784,326 | Jun 01, 2011, 06:15 PM |
| GHDX | Director | May 27, 2011 | Buy | $27.04 | 55,183 | 1,491,922 | 5,729,287 | Jun 01, 2011, 06:15 PM |
| GHDX | Director | Jun 01, 2011 | Buy | $27.49 | 1,706 | 46,894 | 157,271 | Jun 01, 2011, 05:31 PM |
| GHDX | Director | May 31, 2011 | Buy | $27.48 | 1,461 | 40,142 | 155,565 | Jun 01, 2011, 05:31 PM |
| GHDX | Director | May 27, 2011 | Buy | $27.04 | 1,464 | 39,581 | 154,104 | Jun 01, 2011, 05:31 PM |
| GHDX | Director | Jun 01, 2011 | Buy | $27.49 | 44 | 1,209 | 194,296 | Jun 01, 2011, 05:23 PM |
| GHDX | Director | May 31, 2011 | Buy | $27.48 | 34 | 934 | 194,252 | Jun 01, 2011, 05:23 PM |
| GHDX | Director | May 27, 2011 | Buy | $27.04 | 34 | 919 | 194,218 | Jun 01, 2011, 05:23 PM |
| AUXL | 10% Owner | Mar 30, 2011 | Buy | $21.98 | 3,911 | 85,963 | 149,968 | Mar 31, 2011, 06:01 PM |
| AUXL | 10% Owner | Mar 30, 2011 | Buy | $21.98 | 309 | 6,792 | 6,992 | Mar 31, 2011, 05:59 PM |
| AUXL | 10% Owner | Mar 29, 2011 | Buy | $21.98 | 332,000 | 7,298,070 | 6,105,365 | Mar 31, 2011, 05:50 PM |
| GHDX | Director | Mar 10, 2011 | Buy | $25.56 | 20,000 | 511,150 | 5,674,104 | Mar 11, 2011, 04:33 PM |
| GHDX | Director | Mar 09, 2011 | Buy | $26.22 | 50,856 | 1,333,262 | 5,654,104 | Mar 11, 2011, 04:33 PM |
| AUXL | 10% Owner | Mar 08, 2011 | Buy | $22.86 | 5,693 | 130,148 | 146,057 | Mar 10, 2011, 08:04 PM |
| AUXL | 10% Owner | Mar 09, 2011 | Buy | $22.92 | 782,273 | 17,926,169 | 5,773,365 | Mar 10, 2011, 08:03 PM |
| AUXL | 10% Owner | Mar 08, 2011 | Buy | $22.86 | 206,216 | 4,714,316 | 4,991,092 | Mar 10, 2011, 08:03 PM |
| GHDX | Director | Mar 08, 2011 | Buy | $25.13 | 50 | 1,256 | 152,640 | Mar 08, 2011, 05:37 PM |
| GHDX | Director | Mar 07, 2011 | Buy | $24.99 | 8,207 | 205,095 | 152,590 | Mar 08, 2011, 05:37 PM |
| GHDX | Director | Mar 04, 2011 | Buy | $25.45 | 1,391 | 35,405 | 144,383 | Mar 08, 2011, 05:37 PM |
| GHDX | Director | Mar 04, 2011 | Buy | $25.45 | 50,400 | 1,282,845 | 5,304,082 | Mar 08, 2011, 05:33 PM |
| GHDX | Director | Mar 08, 2011 | Buy | $25.13 | 1,826 | 45,887 | 5,603,248 | Mar 08, 2011, 05:33 PM |
| GHDX | Director | Mar 07, 2011 | Buy | $24.99 | 297,340 | 7,430,585 | 5,601,422 | Mar 08, 2011, 05:33 PM |
| GHDX | Director | Mar 02, 2011 | Buy | $26.10 | 74,969 | 1,956,372 | 5,253,682 | Mar 02, 2011, 05:24 PM |
| GHDX | Director | Mar 01, 2011 | Buy | $25.56 | 43,212 | 1,104,574 | 5,178,713 | Mar 02, 2011, 05:24 PM |
| GHDX | Director | Feb 28, 2011 | Buy | $25.10 | 42,156 | 1,058,018 | 5,135,501 | Mar 02, 2011, 05:24 PM |
| GHDX | Director | Feb 28, 2011 | Buy | $25.10 | 1,164 | 29,214 | 139,730 | Mar 02, 2011, 05:12 PM |
| GHDX | Director | Mar 02, 2011 | Buy | $26.10 | 2,069 | 53,992 | 142,992 | Mar 02, 2011, 05:12 PM |
| GHDX | Director | Mar 01, 2011 | Buy | $25.56 | 1,193 | 30,495 | 140,923 | Mar 02, 2011, 05:12 PM |
| SGEN | Director | Feb 02, 2011 | Buy | $15.50 | 48,197 | 747,054 | 303,449 | Feb 04, 2011, 04:53 PM |
| SGEN | Director | Feb 02, 2011 | Buy | $15.50 | 1,751,803 | 27,152,947 | 13,470,692 | Feb 04, 2011, 04:48 PM |
| RDEA | Director | Jan 20, 2011 | Buy | $26.00 | 9,815 | 255,190 | 93,282 | Jan 24, 2011, 04:08 PM |
| ADLR | 10% Owner | Oct 29, 2010 | Sale | $1.18 | 14 | 17 | 2,902 | Oct 29, 2010, 05:31 PM |
| ADLR | 10% Owner | Oct 28, 2010 | Sale | $1.19 | 33 | 39 | 2,916 | Oct 29, 2010, 05:31 PM |
| ADLR | 10% Owner | Oct 27, 2010 | Sale | $1.29 | 30 | 39 | 2,970 | Oct 29, 2010, 05:31 PM |
| ADLR | 10% Owner | Oct 29, 2010 | Sale | $1.18 | 376 | 445 | 79,054 | Oct 29, 2010, 05:24 PM |
| ADLR | 10% Owner | Oct 28, 2010 | Sale | $1.19 | 885 | 1,052 | 79,430 | Oct 29, 2010, 05:24 PM |
| ADLR | 10% Owner | Oct 27, 2010 | Sale | $1.29 | 802 | 1,037 | 80,884 | Oct 29, 2010, 05:24 PM |
| ADLR | 10% Owner | Oct 29, 2010 | Sale | $1.18 | 31,666 | 37,461 | 6,666,436 | Oct 29, 2010, 05:02 PM |
| ADLR | 10% Owner | Oct 28, 2010 | Sale | $1.19 | 74,670 | 88,738 | 6,698,102 | Oct 29, 2010, 05:02 PM |
| ADLR | 10% Owner | Oct 27, 2010 | Sale | $1.29 | 67,649 | 87,491 | 6,820,750 | Oct 29, 2010, 05:02 PM |
| ADLR | 10% Owner | Oct 29, 2010 | Sale | $1.18 | 884 | 1,046 | 186,272 | Oct 29, 2010, 04:58 PM |
| ADLR | 10% Owner | Oct 28, 2010 | Sale | $1.19 | 2,086 | 2,479 | 187,156 | Oct 29, 2010, 04:58 PM |
| ADLR | 10% Owner | Oct 27, 2010 | Sale | $1.29 | 1,891 | 2,446 | 190,583 | Oct 29, 2010, 04:58 PM |
| TRMS | Director | Sep 28, 2010 | Buy | $2.45 | 13,916 | 34,100 | 1,242,773 | Sep 30, 2010, 05:10 PM |
| TRMS | Director | Sep 28, 2010 | Buy | $2.45 | 384 | 941 | 384 | Sep 30, 2010, 04:57 PM |
| INCY | Director | Sep 23, 2010 | Sale | $14.86 | 5,681 | 84,424 | 237,497 | Sep 23, 2010, 05:49 PM |
| INCY | Director | Sep 22, 2010 | Sale | $14.71 | 7,180 | 105,631 | 243,178 | Sep 23, 2010, 05:49 PM |
| INCY | Director | Sep 21, 2010 | Sale | $14.94 | 19,291 | 288,265 | 250,358 | Sep 23, 2010, 05:49 PM |
| INCY | Director | Sep 21, 2010 | Sale | $14.94 | 19,433 | 290,387 | 252,213 | Sep 23, 2010, 05:46 PM |
| INCY | Director | Sep 23, 2010 | Sale | $14.86 | 5,722 | 85,033 | 239,258 | Sep 23, 2010, 05:46 PM |
| INCY | Director | Sep 22, 2010 | Sale | $14.71 | 7,233 | 106,410 | 244,980 | Sep 23, 2010, 05:46 PM |
| INCY | Director | Sep 23, 2010 | Sale | $14.86 | 3,820 | 56,768 | 159,739 | Sep 23, 2010, 05:43 PM |
| INCY | Director | Sep 22, 2010 | Sale | $14.71 | 4,829 | 71,043 | 163,559 | Sep 23, 2010, 05:43 PM |
| INCY | Director | Sep 21, 2010 | Sale | $14.94 | 12,974 | 193,870 | 168,388 | Sep 23, 2010, 05:43 PM |
| INCY | Director | Sep 23, 2010 | Sale | $14.86 | 179,644 | 2,669,654 | 7,511,046 | Sep 23, 2010, 05:39 PM |
| INCY | Director | Sep 22, 2010 | Sale | $14.71 | 227,071 | 3,340,623 | 7,690,690 | Sep 23, 2010, 05:39 PM |
| INCY | Director | Sep 21, 2010 | Sale | $14.94 | 610,072 | 9,116,306 | 7,917,761 | Sep 23, 2010, 05:39 PM |
| GHDX | Director | Sep 09, 2010 | Buy | $14.78 | 40 | 591 | 134,196 | Sep 10, 2010, 04:06 PM |
| GHDX | Director | Sep 08, 2010 | Buy | $14.82 | 105 | 1,556 | 134,156 | Sep 10, 2010, 04:06 PM |
| GHDX | Director | Sep 09, 2010 | Buy | $14.78 | 1,460 | 21,585 | 4,934,990 | Sep 10, 2010, 04:04 PM |
| GHDX | Director | Sep 08, 2010 | Buy | $14.82 | 3,801 | 56,337 | 4,933,530 | Sep 10, 2010, 04:04 PM |
| GHDX | Director | Aug 31, 2010 | Buy | $14.47 | 26,919 | 389,584 | 4,891,182 | Sep 02, 2010, 04:33 PM |
| GHDX | Director | Sep 02, 2010 | Buy | $14.54 | 3,969 | 57,699 | 4,929,729 | Sep 02, 2010, 04:33 PM |
| GHDX | Director | Sep 01, 2010 | Buy | $14.44 | 34,578 | 499,331 | 4,925,760 | Sep 02, 2010, 04:33 PM |
| GHDX | Director | Aug 30, 2010 | Buy | $14.45 | 1,271 | 18,362 | 132,244 | Aug 30, 2010, 05:41 PM |
| GHDX | Director | Aug 27, 2010 | Buy | $14.42 | 1,037 | 14,950 | 130,973 | Aug 30, 2010, 05:41 PM |
| GHDX | Director | Aug 26, 2010 | Buy | $14.24 | 1,107 | 15,766 | 129,936 | Aug 30, 2010, 05:41 PM |
| GHDX | Director | Aug 30, 2010 | Buy | $14.45 | 46,047 | 665,223 | 4,864,263 | Aug 30, 2010, 05:39 PM |
| GHDX | Director | Aug 27, 2010 | Buy | $14.42 | 37,561 | 541,502 | 4,818,216 | Aug 30, 2010, 05:39 PM |
| GHDX | Director | Aug 26, 2010 | Buy | $14.24 | 40,103 | 571,161 | 4,780,655 | Aug 30, 2010, 05:39 PM |
| AUXL | 10% Owner | Aug 27, 2010 | Buy | $25.82 | 964 | 24,892 | 140,364 | Aug 30, 2010, 04:47 PM |
| AUXL | 10% Owner | Aug 26, 2010 | Buy | $25.36 | 2,088 | 52,951 | 139,400 | Aug 30, 2010, 04:47 PM |
| AUXL | 10% Owner | Aug 27, 2010 | Buy | $25.82 | 34,899 | 901,141 | 4,784,876 | Aug 30, 2010, 04:45 PM |
| AUXL | 10% Owner | Aug 26, 2010 | Buy | $25.36 | 75,648 | 1,918,414 | 4,749,977 | Aug 30, 2010, 04:45 PM |
| GHDX | Director | Aug 19, 2010 | Buy | $14.63 | 55,305 | 808,993 | 4,645,388 | Aug 23, 2010, 05:18 PM |
| GHDX | Director | Aug 23, 2010 | Buy | $14.44 | 67,892 | 980,509 | 4,740,552 | Aug 23, 2010, 05:18 PM |
| GHDX | Director | Aug 20, 2010 | Buy | $14.52 | 27,272 | 395,875 | 4,672,660 | Aug 23, 2010, 05:18 PM |
| GHDX | Director | Aug 23, 2010 | Buy | $14.44 | 1,874 | 27,065 | 128,829 | Aug 23, 2010, 05:17 PM |
| GHDX | Director | Aug 20, 2010 | Buy | $14.52 | 752 | 10,916 | 126,955 | Aug 23, 2010, 05:17 PM |
| GHDX | Director | Aug 19, 2010 | Buy | $14.63 | 1,527 | 22,337 | 126,203 | Aug 23, 2010, 05:17 PM |
| GHDX | Director | Aug 18, 2010 | Buy | $15.00 | 51 | 765 | 124,676 | Aug 18, 2010, 04:50 PM |
| GHDX | Director | Aug 16, 2010 | Buy | $14.99 | 479 | 7,178 | 124,625 | Aug 18, 2010, 04:50 PM |
| GHDX | Director | Aug 18, 2010 | Buy | $15.00 | 1,845 | 27,675 | 4,590,083 | Aug 18, 2010, 04:48 PM |
| GHDX | Director | Aug 16, 2010 | Buy | $14.99 | 17,342 | 259,877 | 4,588,238 | Aug 18, 2010, 04:48 PM |
| GHDX | Director | Aug 13, 2010 | Buy | $14.84 | 1,309 | 19,425 | 124,146 | Aug 13, 2010, 04:35 PM |
| GHDX | Director | Aug 12, 2010 | Buy | $14.99 | 836 | 12,529 | 122,837 | Aug 13, 2010, 04:35 PM |
| GHDX | Director | Aug 11, 2010 | Buy | $14.73 | 779 | 11,474 | 122,001 | Aug 13, 2010, 04:35 PM |
| GHDX | Director | Aug 11, 2010 | Buy | $14.73 | 28,206 | 415,465 | 4,493,192 | Aug 13, 2010, 04:30 PM |
| GHDX | Director | Aug 13, 2010 | Buy | $14.84 | 47,408 | 703,529 | 4,570,896 | Aug 13, 2010, 04:30 PM |
| GHDX | Director | Aug 12, 2010 | Buy | $14.99 | 30,296 | 454,040 | 4,523,488 | Aug 13, 2010, 04:30 PM |
| INCY | Director | Aug 10, 2010 | Sale | $14.00 | 2,812 | 39,364 | 273,502 | Aug 11, 2010, 05:31 PM |
| INCY | Director | Aug 09, 2010 | Sale | $14.08 | 9,991 | 140,710 | 280,511 | Aug 11, 2010, 05:31 PM |
| INCY | Director | Aug 10, 2010 | Sale | $14.00 | 1,877 | 26,275 | 182,601 | Aug 11, 2010, 05:24 PM |
| INCY | Director | Aug 09, 2010 | Sale | $14.08 | 6,670 | 93,938 | 187,280 | Aug 11, 2010, 05:24 PM |
| INCY | Director | Aug 09, 2010 | Sale | $14.08 | 122,467 | 1,724,784 | 3,438,734 | Aug 11, 2010, 05:22 PM |
| INCY | Director | Aug 10, 2010 | Sale | $14.00 | 34,462 | 482,421 | 3,352,822 | Aug 11, 2010, 05:22 PM |
| INCY | Director | Aug 10, 2010 | Sale | $14.00 | 88,250 | 1,235,380 | 8,586,095 | Aug 11, 2010, 05:21 PM |
| INCY | Director | Aug 09, 2010 | Sale | $14.08 | 313,622 | 4,416,947 | 8,806,103 | Aug 11, 2010, 05:21 PM |
| INCY | Director | Aug 10, 2010 | Sale | $14.00 | 2,789 | 39,042 | 271,491 | Aug 11, 2010, 05:18 PM |
| INCY | Director | Aug 09, 2010 | Sale | $14.08 | 9,916 | 139,654 | 278,447 | Aug 11, 2010, 05:18 PM |
| GHDX | Director | Aug 06, 2010 | Buy | $14.16 | 44,927 | 636,250 | 4,345,671 | Aug 10, 2010, 05:04 PM |
| GHDX | Director | Aug 10, 2010 | Buy | $14.75 | 56,705 | 836,217 | 4,464,986 | Aug 10, 2010, 05:04 PM |
| GHDX | Director | Aug 09, 2010 | Buy | $14.81 | 62,610 | 927,144 | 4,408,281 | Aug 10, 2010, 05:04 PM |
| GHDX | Director | Aug 10, 2010 | Buy | $14.75 | 1,565 | 23,079 | 121,222 | Aug 10, 2010, 05:00 PM |
| GHDX | Director | Aug 09, 2010 | Buy | $14.81 | 1,728 | 25,589 | 119,657 | Aug 10, 2010, 05:00 PM |
| GHDX | Director | Aug 06, 2010 | Buy | $14.16 | 1,240 | 17,561 | 117,929 | Aug 10, 2010, 05:00 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| NLTX | Director | Aug 17, 2023 | Buy | 115,617 |
| NLTX | Director | Aug 16, 2023 | Buy | 156,254 |
| NLTX | Director | Aug 15, 2023 | Buy | 1,191,616 |
| ACAD | Director | May 23, 2023 | Option Exercise | 425,250 |
| ACAD | Director | May 22, 2023 | Buy | 3,297,815 |
| ACAD | Director | May 24, 2023 | Buy | 14,096,825 |
| ACAD | Director | May 23, 2023 | Buy | 5,312,458 |
| SGEN | Director | May 01, 2023 | Option Exercise | 642,250 |
| INCY | Director | Mar 13, 2023 | Option Exercise | 909,600 |
| ACAD | Director | Jan 12, 2023 | Option Exercise | 156,600 |
| KOD | Director | Jun 03, 2022 | Buy | 812,481 |
| KOD | Director | Jun 02, 2022 | Buy | 1,274,594 |
| KOD | Director | Jun 06, 2022 | Buy | 2,361,093 |
| TRDA | 10% Owner | Jun 06, 2022 | Buy | 245,377 |
| TRDA | 10% Owner | Jun 02, 2022 | Buy | 15,383 |
| KOD | Director | May 27, 2022 | Buy | 1,071,030 |
| KOD | Director | May 26, 2022 | Buy | 628,583 |
| KOD | Director | May 25, 2022 | Buy | 664,135 |
| TRDA | 10% Owner | May 24, 2022 | Buy | 137,100 |
| TRDA | 10% Owner | May 23, 2022 | Buy | 46,923 |
| TRDA | 10% Owner | May 20, 2022 | Buy | 98,424 |
| TRDA | 10% Owner | May 18, 2022 | Buy | 206,534 |
| TRDA | 10% Owner | May 17, 2022 | Buy | 113,474 |
| TRDA | 10% Owner | May 16, 2022 | Buy | 110,692 |
| KOD | Director | May 18, 2022 | Buy | 1,335,419 |
| KOD | Director | May 17, 2022 | Buy | 663,571 |
| KOD | Director | May 16, 2022 | Buy | 697,839 |
| TCRX | Director | May 11, 2022 | Buy | 51,350 |
| TCRX | Director | May 10, 2022 | Buy | 2,507,804 |
| INCY | Director | Mar 08, 2022 | Option Exercise | 882,000 |
| INCY | Director | Mar 09, 2022 | Buy | 5,057,550 |
| INCY | Director | Mar 08, 2022 | Buy | 7,067,500 |
| INCY | Director | Mar 10, 2022 | Buy | 15,982,720 |
| SGEN | Director | Mar 08, 2022 | Option Exercise | 702,100 |
| INCY | Director | Feb 22, 2022 | Buy | 6,793,536 |
| INCY | Director | Feb 18, 2022 | Buy | 9,096,550 |
| INCY | Director | Feb 17, 2022 | Buy | 19,844,806 |
| KOD | Director | Feb 16, 2022 | Buy | 5,150,173 |
| KOD | Director | Feb 15, 2022 | Buy | 314,099 |
| KOD | Director | Feb 17, 2022 | Buy | 16,367,881 |
| KOD | Director | Jan 31, 2022 | Buy | 1,725,084 |
| KOD | Director | Jan 28, 2022 | Buy | 2,786,084 |
| KOD | Director | Jan 27, 2022 | Buy | 13,573,519 |
| KOD | Director | Jan 24, 2022 | Buy | 20,905,291 |
| KOD | Director | Jan 21, 2022 | Buy | 7,577,571 |
| KOD | Director | Jan 25, 2022 | Buy | 323,934 |
| INCY | Director | Dec 17, 2021 | Buy | 78,322,147 |
| INCY | Director | Dec 16, 2021 | Buy | 12,184,412 |
| INCY | Director | Dec 15, 2021 | Buy | 25,052,340 |
| SGEN | Director | Dec 01, 2021 | Sale | 15,064,917 |
| SGEN | Director | Nov 30, 2021 | Sale | 48,331,458 |
| TLIS | Director | Nov 18, 2021 | Buy | 218,250 |
| KOD | Director | Sep 29, 2021 | Option Exercise | 1,632 |
| KOD | Director | Sep 29, 2021 | Option Exercise | 1,500 |
| KOD | Director | Sep 30, 2021 | Buy | 8,330,572 |
| KOD | Director | Sep 16, 2021 | Buy | 109,064 |
| KOD | Director | Sep 15, 2021 | Buy | 2,896,217 |
| KOD | Director | Sep 07, 2021 | Buy | 5,365,227 |
| KOD | Director | Aug 19, 2021 | Buy | 7,323,898 |
| KOD | Director | Aug 18, 2021 | Buy | 1,984,806 |
| KOD | Director | Aug 17, 2021 | Buy | 701,254 |
| KOD | Director | Aug 11, 2021 | Buy | 4,609,090 |
| KOD | Director | Aug 13, 2021 | Buy | 3,392,579 |
| KOD | Director | Aug 12, 2021 | Buy | 958,954 |
| TCRX | Director | Jul 20, 2021 | Buy | 21,375,000 |
| KOD | Director | Jun 30, 2021 | Buy | 14,350,693 |
| KOD | Director | Jun 29, 2021 | Buy | 4,892,033 |
| KOD | Director | Jun 28, 2021 | Buy | 4,413,705 |
| TLIS | Director | Feb 17, 2021 | Buy | 100,000,000 |
| PRLD | Director | Jan 27, 2021 | Option Exercise | 133,332 |
| IGMS | Director | Jan 27, 2021 | Option Exercise | 641,854 |
| BGNE | Director | Jan 04, 2021 | Sale | 26,714,457 |
| NLTX | Director | Jul 07, 2020 | Buy | 6,466,000 |
| BGNE | Director | Dec 04, 2020 | Sale | 333,295,893 |
| KOD | Director | Nov 20, 2020 | Buy | 164,999,916 |
| PRLD | Director | Sep 29, 2020 | Buy | 29,999,993 |
| KOD | Director | Sep 25, 2020 | Buy | 2,726,182 |
| KOD | Director | Sep 24, 2020 | Buy | 1,873,924 |
| KOD | Director | Sep 23, 2020 | Buy | 4,826,756 |
| KOD | Director | Sep 22, 2020 | Buy | 3,797,911 |
| KOD | Director | Sep 08, 2020 | Buy | 5,505,934 |
| KOD | Director | Sep 04, 2020 | Buy | 3,869,474 |
| KOD | Director | Sep 03, 2020 | Buy | 5,942,904 |
| KOD | Director | Aug 21, 2020 | Buy | 6,762,056 |
| KOD | Director | Aug 20, 2020 | Buy | 2,871,156 |
| KOD | Director | Aug 19, 2020 | Buy | 181,791 |
| BGNE | Director | Jul 15, 2020 | Option Exercise | 207,544,544 |
| INCY | Director | May 28, 2020 | Buy | 205 |
| SGEN | Director | May 15, 2020 | Sale | 280,000,000 |
| SGEN | Director | May 08, 2020 | Sale | 79,250,000 |
| SGEN | Director | May 07, 2020 | Sale | 27,660,924 |
| SGEN | Director | May 06, 2020 | Sale | 64,379,426 |
| INCY | Director | Apr 28, 2020 | Option Exercise | 533,600 |
| SGEN | Director | Apr 23, 2020 | Option Exercise | 446,600 |
| INCY | Director | Mar 31, 2020 | Option Exercise | 57,412 |
| ACAD | Director | Mar 18, 2020 | Buy | 4,555,101 |
| ACAD | Director | Mar 17, 2020 | Buy | 7,218,907 |
| ACAD | Director | Mar 16, 2020 | Buy | 21,878,017 |
| KOD | Director | Mar 18, 2020 | Buy | 1,322,977 |
| KOD | Director | Mar 17, 2020 | Buy | 389,850 |
| KOD | Director | Mar 16, 2020 | Buy | 4,180,977 |
| ALXN | Director | Mar 18, 2020 | Buy | 6,673,935 |
| ALXN | Director | Mar 17, 2020 | Buy | 7,836,585 |
| ALXN | Director | Mar 16, 2020 | Buy | 20,894,753 |
| ALXN | Director | Mar 18, 2020 | Buy | 4,059,792 |
| KOD | Director | Feb 26, 2020 | Buy | 5,799,441 |
| KOD | Director | Feb 25, 2020 | Buy | 11,937,248 |
| KOD | Director | Feb 24, 2020 | Buy | 4,093,553 |
| NLTX | Director | Dec 20, 2019 | Buy | 25,347,352 |
| KOD | Director | Dec 06, 2019 | Buy | 87,499,958 |
| GHDX | Director | Oct 01, 2019 | Option Exercise | 124,468 |
| INCY | Director | Sep 30, 2019 | Option Exercise | 54,039 |
| IGMS | Director | Sep 20, 2019 | Buy | 50,304,000 |
| ACAD | Director | Sep 20, 2019 | Buy | 62,500,000 |
| KOD | Director | Sep 19, 2019 | Option Exercise | 0 |
| AQXP | Director | Aug 07, 2019 | Buy | 882,884 |
| AQXP | Director | Aug 06, 2019 | Buy | 232,731 |
| GHDX | Director | Jul 01, 2019 | Option Exercise | 149,740 |
| IDRA | 10% Owner | Jul 01, 2019 | Option Exercise | 15,472 |
| INCY | Director | Jun 28, 2019 | Option Exercise | 52,675 |
| ALXN | Director | May 28, 2019 | Sale | 15,624,840 |
| ALXN | Director | May 30, 2019 | Sale | 6,949,741 |
| ALXN | Director | May 29, 2019 | Sale | 14,548,848 |
| SGEN | Director | Apr 29, 2019 | Option Exercise | 167,600 |
| HOOK | Former 10% owner | Apr 23, 2019 | Buy | 12,499,998 |
| GHDX | Director | Apr 12, 2019 | Sale | 731,889 |
| GHDX | Director | Apr 12, 2019 | Sale | 18,770,152 |
| GHDX | Director | Apr 11, 2019 | Sale | 13,533,252 |
| GHDX | Director | Apr 10, 2019 | Sale | 908,684 |
| GHDX | Director | Apr 10, 2019 | Sale | 8,556,110 |
| GHDX | Director | Apr 09, 2019 | Sale | 1,425,885 |
| GHDX | Director | Apr 08, 2019 | Sale | 1,537,720 |
| GHDX | Director | Apr 05, 2019 | Sale | 5,333,397 |
| GHDX | Director | Apr 04, 2019 | Sale | 5,401,340 |
| GHDX | Director | Apr 03, 2019 | Sale | 6,701,718 |
| IDRA | Director | Apr 01, 2019 | Option Exercise | 32,331 |
| GHDX | Director | Apr 01, 2019 | Option Exercise | 119,510 |
| INCY | Director | Mar 29, 2019 | Option Exercise | 56,767 |
| GHDX | Director | Mar 21, 2019 | Sale | 4,232,164 |
| GHDX | Director | Mar 19, 2019 | Sale | 3,724,594 |
| GHDX | Director | Mar 19, 2019 | Sale | 3,724,594 |
| GHDX | Director | Mar 19, 2019 | Sale | 7,845,648 |
| GHDX | Director | Mar 18, 2019 | Sale | 8,125,969 |
| GHDX | Director | Mar 15, 2019 | Sale | 4,131,088 |
| GHDX | Director | Mar 14, 2019 | Sale | 4,978,787 |
| GHDX | Director | Mar 13, 2019 | Sale | 6,092,923 |
| GHDX | Director | Mar 12, 2019 | Sale | 5,610,248 |
| GHDX | Director | Mar 11, 2019 | Sale | 3,677,484 |
| GHDX | Director | Mar 08, 2019 | Sale | 1,669,519 |
| GHDX | Director | Mar 07, 2019 | Sale | 147,445 |
| GHDX | Director | Mar 05, 2019 | Sale | 793,504 |
| GHDX | Director | Mar 04, 2019 | Sale | 2,127,250 |
| GHDX | Director | Mar 01, 2019 | Sale | 6,120,387 |
| GHDX | Director | Feb 28, 2019 | Sale | 45,719 |
| GHDX | Director | Feb 26, 2019 | Option Exercise | 290,235 |
| GHDX | Director | Feb 26, 2019 | Sale | 675,614 |
| GHDX | Director | Feb 27, 2019 | Sale | 2,997,792 |
| INCY | Director | Feb 26, 2019 | Option Exercise | 112,000 |
| GHDX | Director | Jan 28, 2019 | Sale | 3,302,980 |
| GHDX | Director | Jan 24, 2019 | Sale | 5,718,588 |
| GHDX | Director | Jan 23, 2019 | Sale | 2,651,092 |
| GHDX | Director | Jan 25, 2019 | Sale | 6,636,648 |
| GHDX | Director | Jan 22, 2019 | Sale | 3,664,031 |
| GHDX | Director | Jan 22, 2019 | Sale | 916,641 |
| GHDX | Director | Jan 18, 2019 | Sale | 12,884,344 |
| GHDX | Director | Jan 17, 2019 | Sale | 12,866,124 |
| GHDX | Director | Jan 11, 2019 | Sale | 1,999,533 |
| GHDX | Director | Jan 10, 2019 | Sale | 715,780 |
| GHDX | Director | Jan 14, 2019 | Sale | 42,043 |
| IDRA | Director | Jan 02, 2019 | Option Exercise | 38,628 |
| INCY | Director | Dec 31, 2018 | Option Exercise | 56,849 |
| GHDX | Director | Dec 12, 2018 | Sale | 1,352,087 |
| GHDX | Director | Dec 11, 2018 | Sale | 4,262,823 |
| GHDX | Director | Dec 10, 2018 | Sale | 691,483 |
| GHDX | Director | Dec 07, 2018 | Sale | 7,802,358 |
| GHDX | Director | Dec 06, 2018 | Sale | 6,993,622 |
| GHDX | Director | Dec 04, 2018 | Sale | 2,478,447 |
| ACAD | Director | Nov 30, 2018 | Buy | 199,999,985 |
| GHDX | Director | Dec 03, 2018 | Sale | 15,865,833 |
| GHDX | Director | Nov 30, 2018 | Sale | 16,217,023 |
| GHDX | Director | Nov 29, 2018 | Sale | 3,997,192 |
| GHDX | Director | Nov 28, 2018 | Sale | 18,932,284 |
| GHDX | Director | Nov 27, 2018 | Sale | 10,269,089 |
| GHDX | Director | Nov 26, 2018 | Sale | 2,947,113 |
| GHDX | Director | Nov 16, 2018 | Sale | 6,699,000 |
| GHDX | Director | Nov 13, 2018 | Sale | 9,153,058 |
| GHDX | Director | Nov 13, 2018 | Sale | 10,889,359 |
| GHDX | Director | Nov 12, 2018 | Sale | 5,317,265 |
| GHDX | Director | Nov 09, 2018 | Sale | 13,972,201 |
| GHDX | Director | Nov 12, 2018 | Sale | 1,158,724 |
| GHDX | Director | Nov 09, 2018 | Sale | 9,018,337 |
| GHDX | Director | Nov 08, 2018 | Sale | 6,597,504 |
| GHDX | Director | Nov 08, 2018 | Sale | 6,225,158 |
| KOD | Director | Oct 09, 2018 | Option Exercise | 3,955,935 |
| KOD | Director | Oct 09, 2018 | Buy | 25,000,000 |
| IDRA | Director | Oct 01, 2018 | Option Exercise | 61,144 |
| GHDX | Director | Oct 01, 2018 | Option Exercise | 119,587 |
| INCY | Director | Sep 28, 2018 | Option Exercise | 56,991 |
| ACAD | Director | Sep 20, 2018 | Buy | 22,646,990 |
| BGNE | Director | Aug 02, 2018 | Buy | 627,922,800 |
| IDRA | Director | Jul 02, 2018 | Option Exercise | 64,877 |
| INCY | Director | Jun 29, 2018 | Option Exercise | 56,883 |
| KNSA | Director | May 29, 2018 | Buy | 54,000,000 |
| SGEN | Director | May 18, 2018 | Option Exercise | 420,098 |
| SGEN | Director | May 04, 2018 | Buy | 10,775,582 |
| SGEN | Director | May 08, 2018 | Buy | 6,828,339 |
| SGEN | Director | May 07, 2018 | Buy | 6,966,305 |
| INCY | Director | May 02, 2018 | Option Exercise | 595,200 |
| SGEN | Director | May 01, 2018 | Option Exercise | 201,600 |
| SGEN | Director | May 02, 2018 | Buy | 3,676,836 |
| SGEN | Director | May 01, 2018 | Buy | 15,764,736 |
| SGEN | Director | Apr 30, 2018 | Buy | 31,816,925 |
| IDRA | Director | Apr 02, 2018 | Option Exercise | 64,876 |
| GHDX | Director | Apr 01, 2018 | Option Exercise | 119,778 |
| INCY | Director | Mar 29, 2018 | Option Exercise | 56,998 |
| NVTA | 10% Owner | Mar 28, 2018 | Buy | 5,000,000 |
| IDRA | Director | Mar 15, 2018 | Option Exercise | 9,548,674 |
| GHDX | Director | Mar 09, 2018 | Option Exercise | 915,750 |
| SGEN | Director | Feb 01, 2018 | Buy | 20,259,720 |
| SGEN | Director | Feb 01, 2018 | Buy | 179,740,236 |
| BGNE | Director | Jan 18, 2018 | Buy | 199,999,998 |
| BLCM | 10% Owner | Jan 19, 2018 | Sale | 2,336,217 |
| BLCM | 10% Owner | Jan 18, 2018 | Sale | 2,635,768 |
| BLCM | 10% Owner | Jan 17, 2018 | Sale | 2,247,910 |
| IDRA | Director | Jan 02, 2018 | Option Exercise | 61,878 |
| INCY | Director | Dec 29, 2017 | Option Exercise | 56,826 |
| ACAD | Director | Nov 27, 2017 | Option Exercise | 54,348 |
| ACAD | Director | Nov 27, 2017 | Option Exercise | 54,342 |
| MRTX | 10% Owner | Nov 08, 2017 | Option Exercise | 2,202,867 |
| IDRA | Director | Oct 26, 2017 | Buy | 12,000,000 |
| ACAD | Director | Oct 13, 2017 | Option Exercise | 1,963,178 |
| ACAD | Director | Oct 13, 2017 | Option Exercise | 1,968,694 |
| RYTM | Former 10% owner | Oct 05, 2017 | Buy | 15,045,000 |
| IDRA | Director | Oct 02, 2017 | Option Exercise | 61,868 |
| GHDX | Director | Oct 01, 2017 | Option Exercise | 119,760 |
| INCY | Director | Sep 29, 2017 | Option Exercise | 56,736 |
| INCY | Director | Sep 08, 2017 | Buy | 13,200,000 |
| BGNE | Director | Aug 11, 2017 | Buy | 12,499,976 |
| IDRA | Director | Jul 03, 2017 | Option Exercise | 61,882 |
| GHDX | Director | Jul 01, 2017 | Option Exercise | 119,914 |
| INCY | Director | Jun 30, 2017 | Option Exercise | 56,660 |
| ALXN | Director | Jun 15, 2017 | Buy | 77,012,514 |
| ALXN | Director | Jun 14, 2017 | Buy | 518,256 |
| ALXN | Director | Jun 14, 2017 | Buy | 156,915,230 |
| GHDX | Director | May 31, 2017 | Option Exercise | 897,435 |
| SGEN | Director | May 19, 2017 | Option Exercise | 246,420 |
| SGEN | Director | May 19, 2017 | Option Exercise | 246,420 |
| SGEN | Director | May 15, 2017 | Option Exercise | 204,000 |
| INCY | Director | Apr 27, 2017 | Option Exercise | 435,600 |
| IDRA | Director | Apr 03, 2017 | Option Exercise | 61,870 |
| INCY | Director | Mar 31, 2017 | Option Exercise | 56,943 |
| GHDX | Director | Apr 01, 2017 | Option Exercise | 119,788 |
| BLCM | 10% Owner | Mar 24, 2017 | Buy | 1,999,992 |
| AQXP | 10% Owner | Jan 09, 2017 | Buy | 6,836,813 |
| IDRA | Director | Jan 03, 2017 | Option Exercise | 63,761 |
| GHDX | Director | Jan 01, 2017 | Option Exercise | 119,911 |
| INCY | Director | Dec 30, 2016 | Option Exercise | 56,853 |
| BGNE | Director | Nov 18, 2016 | Buy | 56,335,840 |
| NVTA | 10% Owner | Nov 17, 2016 | Buy | 4,399,998 |
| SGEN | Director | Nov 08, 2016 | Buy | 19,403,299 |
| SGEN | Director | Nov 07, 2016 | Buy | 3,301,345 |
| SGEN | Director | Nov 03, 2016 | Buy | 11,196,763 |
| SGEN | Director | Nov 03, 2016 | Buy | 21,586,885 |
| SGEN | Director | Nov 02, 2016 | Buy | 26,200,958 |
| SGEN | Director | Nov 01, 2016 | Buy | 10,057,349 |
| IDRA | Director | Oct 07, 2016 | Buy | 6,500,000 |
| IDRA | Director | Oct 03, 2016 | Option Exercise | 63,736 |
| GHDX | Director | Sep 30, 2016 | Option Exercise | 119,729 |
| INCY | Director | Sep 30, 2016 | Option Exercise | 56,857 |
| AQXP | 10% Owner | Sep 20, 2016 | Buy | 34,110,452 |
| SGEN | Director | Sep 12, 2016 | Buy | 2,551,111 |
| SGEN | Director | Sep 09, 2016 | Buy | 12,917,842 |
| SGEN | Director | Sep 13, 2016 | Buy | 7,213,981 |
| SGEN | Director | Sep 08, 2016 | Buy | 10,579,529 |
| SGEN | Director | Sep 07, 2016 | Buy | 2,889,689 |
| SGEN | Director | Sep 06, 2016 | Buy | 6,580,527 |
| BCRX | 10% Owner | Aug 15, 2016 | Sale | 1,931,040 |
| BCRX | 10% Owner | Aug 12, 2016 | Sale | 18,315,817 |
| BCRX | 10% Owner | Aug 16, 2016 | Sale | 4,246 |
| GHDX | Director | Aug 15, 2016 | Buy | 2,701,590 |
| ACAD | Director | Aug 10, 2016 | Buy | 42,999,990 |
| GHDX | Director | Jul 01, 2016 | Option Exercise | 119,688 |
| IDRA | Director | Jul 01, 2016 | Option Exercise | 63,756 |
| INCY | Director | Jun 30, 2016 | Option Exercise | 56,866 |
| MRTX | 10% Owner | Jun 09, 2016 | Sale | 5,150,516 |
| MRTX | 10% Owner | Jun 08, 2016 | Sale | 1,456,481 |
| MRTX | 10% Owner | Jun 07, 2016 | Sale | 2,795,476 |
| SGEN | Director | May 20, 2016 | Option Exercise | 287,268 |
| GHDX | Director | May 17, 2016 | Option Exercise | 531,135 |
| NTLA | Former 10% owner | May 11, 2016 | Buy | 3,600,000 |
| IDRA | Director | Apr 01, 2016 | Option Exercise | 63,757 |
| GHDX | Director | Apr 01, 2016 | Option Exercise | 119,858 |
| INCY | Director | Mar 31, 2016 | Option Exercise | 56,961 |
| MRTX | 10% Owner | Mar 30, 2016 | Option Exercise | 2,112,869 |
| MRTX | 10% Owner | Mar 30, 2016 | Option Exercise | 1,847 |
| ACAD | Director | Mar 30, 2016 | Buy | 12,000,056 |
| ACAD | Director | Apr 01, 2016 | Buy | 8,638,572 |
| ACAD | Director | Mar 31, 2016 | Buy | 18,601,181 |
| SGEN | Director | Mar 17, 2016 | Buy | 3,951,304 |
| INCY | Director | Mar 17, 2016 | Option Exercise | 231,600 |
| INCY | Director | Mar 17, 2016 | Buy | 24,595,777 |
| INCY | Director | Mar 15, 2016 | Buy | 26,588,417 |
| SGEN | Director | Mar 15, 2016 | Buy | 21,210,834 |
| SGEN | Director | Mar 14, 2016 | Buy | 4,016,519 |
| SGEN | Director | Mar 16, 2016 | Buy | 18,084,599 |
| AQXP | 10% Owner | Mar 16, 2016 | Buy | 2,893,570 |
| AQXP | 10% Owner | Mar 15, 2016 | Buy | 850,484 |
| AQXP | 10% Owner | Mar 15, 2016 | Buy | 26,582 |
| SGEN | Director | Mar 09, 2016 | Buy | 6,683,985 |
| SGEN | Director | Mar 11, 2016 | Buy | 6,480,738 |
| SGEN | Director | Mar 10, 2016 | Buy | 9,386,567 |
| SGEN | Director | Mar 02, 2016 | Buy | 13,068,812 |
| SGEN | Director | Mar 01, 2016 | Buy | 756,112 |
| SGEN | Director | Feb 29, 2016 | Buy | 7,650,310 |
| SGEN | Director | Feb 26, 2016 | Buy | 1,334,945 |
| SGEN | Director | Feb 25, 2016 | Buy | 4,261,553 |
| SGEN | Director | Feb 24, 2016 | Buy | 3,696,568 |
| INCY | Director | Feb 25, 2016 | Buy | 495,800 |
| INCY | Director | Feb 24, 2016 | Buy | 4,055,187 |
| SGEN | Director | Feb 22, 2016 | Buy | 7,354,639 |
| SGEN | Director | Feb 19, 2016 | Buy | 14,790,560 |
| SGEN | Director | Feb 18, 2016 | Buy | 7,530,350 |
| SGEN | Director | Feb 16, 2016 | Buy | 8,049,663 |
| SGEN | Director | Feb 12, 2016 | Buy | 5,410,745 |
| SGEN | Director | Feb 17, 2016 | Buy | 25,161,937 |
| INCY | Director | Feb 16, 2016 | Buy | 47,973,375 |
| INCY | Director | Feb 12, 2016 | Buy | 14,010,425 |
| INCY | Director | Feb 12, 2016 | Buy | 60,732,037 |
| INCY | Director | Feb 11, 2016 | Buy | 82,297,659 |
| BGNE | Director | Feb 08, 2016 | Buy | 45,904,320 |
| BGNE | Director | Feb 08, 2016 | Option Exercise | 1,750,000 |
| BCRX | 10% Owner | Feb 05, 2016 | Buy | 284,656 |
| BCRX | 10% Owner | Feb 04, 2016 | Buy | 164,915 |
| BCRX | 10% Owner | Feb 03, 2016 | Buy | 573,311 |
| BCRX | 10% Owner | Feb 02, 2016 | Buy | 598,360 |
| BCRX | 10% Owner | Jan 28, 2016 | Buy | 172,015 |
| BCRX | 10% Owner | Jan 27, 2016 | Buy | 441,971 |
| AQXP | 10% Owner | Jan 26, 2016 | Buy | 839,524 |
| AQXP | 10% Owner | Jan 25, 2016 | Buy | 121,576 |
| AQXP | 10% Owner | Jan 22, 2016 | Buy | 539,465 |
| AQXP | 10% Owner | Jan 22, 2016 | Buy | 20,345 |
| BCRX | 10% Owner | Jan 21, 2016 | Buy | 755,368 |
| BCRX | 10% Owner | Jan 22, 2016 | Buy | 22,389 |
| BCRX | 10% Owner | Jan 20, 2016 | Buy | 362,171 |
| BCRX | 10% Owner | Jan 19, 2016 | Buy | 656,750 |
| BCRX | 10% Owner | Jan 15, 2016 | Buy | 1,491,222 |
| AQXP | 10% Owner | Jan 19, 2016 | Buy | 45,642 |
| AQXP | 10% Owner | Jan 20, 2016 | Buy | 1,062,538 |
| AQXP | 10% Owner | Jan 19, 2016 | Buy | 665,474 |
| AQXP | 10% Owner | Jan 15, 2016 | Buy | 717,201 |
| AQXP | 10% Owner | Jan 14, 2016 | Buy | 878,410 |
| AQXP | 10% Owner | Jan 14, 2016 | Buy | 81,472 |
| AQXP | 10% Owner | Jan 15, 2016 | Buy | 717,201 |
| AQXP | 10% Owner | Jan 14, 2016 | Buy | 878,410 |
| AQXP | 10% Owner | Jan 14, 2016 | Buy | 81,472 |
| ACAD | Director | Jan 07, 2016 | Buy | 74,999,974 |
| ACAD | Director | Jan 07, 2016 | Buy | 74,999,974 |
| IDRA | Director | Jan 04, 2016 | Option Exercise | 63,738 |
| GHDX | Director | Jan 01, 2016 | Option Exercise | 119,962 |
| INCY | Director | Dec 31, 2015 | Option Exercise |