| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| ZLAB | Director | Dec 08, 2021 | Buy | $71.36 | 4,000 | 285,440 | 4,000 | Dec 12, 2022, 04:05 PM |
| ZLAB | Director | Dec 08, 2022 | Sale | $35.33 | 4,000 | 141,320 | 0 | Dec 09, 2022, 04:05 PM |
| ZLAB | Director | Dec 08, 2022 | Sale | $35.37 | 3,852 | 136,245 | 342,763 | Dec 09, 2022, 04:05 PM |
| ZLAB | Director | Dec 08, 2021 | Buy | $71.36 | 4,000 | 285,440 | 342,852 | Dec 08, 2021, 08:56 PM |
| GENZ | Exec VP,Legal & Corporate Dev. | Apr 04, 2011 | Option Exercise | $74.00 | 29,250 | 2,164,500 | 0 | Apr 06, 2011, 11:49 AM |
| GENZ | Exec VP,Legal & Corporate Dev. | Apr 04, 2011 | Option Exercise | $74.00 | 15,660 | 1,158,840 | 29,250 | Apr 06, 2011, 11:49 AM |
| GENZ | Exec VP,Legal & Corporate Dev. | Apr 04, 2011 | Option Exercise | $74.00 | 148 | 10,952 | 0 | Apr 06, 2011, 11:49 AM |
| Symbol | Relationship | Date | Transaction | Value($) |
| ZLAB | Director | Dec 08, 2021 | Buy | 285,440 |
| ZLAB | Director | Dec 08, 2022 | Sale | 141,320 |
| ZLAB | Director | Dec 08, 2022 | Sale | 136,245 |
| ZLAB | Director | Dec 08, 2021 | Buy | 285,440 |
| GENZ | Exec VP,Legal & Corporate Dev. | Apr 04, 2011 | Option Exercise | 2,164,500 |
| GENZ | Exec VP,Legal & Corporate Dev. | Apr 04, 2011 | Option Exercise | 1,158,840 |
| GENZ | Exec VP,Legal & Corporate Dev. | Apr 04, 2011 | Option Exercise | 10,952 |