Insider Transactions for Relypsa Inc (RLYP)

Owner Relationship Date Transaction Cost # Shares Value($) Total Shares Form 4
Torley Helen Director Sep 01, 2016 Option Exercise $32.00 2,250 72,000 0 Sep 02, 2016, 12:39 PM
Torley Helen Director Sep 01, 2016 Option Exercise $32.00 1,237 39,584 2,250 Sep 02, 2016, 12:39 PM
SPIEGELMAN DANIEL K Director Sep 01, 2016 Option Exercise $32.00 2,250 72,000 0 Sep 02, 2016, 12:38 PM
SPIEGELMAN DANIEL K Director Sep 01, 2016 Option Exercise $32.00 1,237 39,584 2,250 Sep 02, 2016, 12:38 PM
Schuetz Thomas J. Director Sep 01, 2016 Option Exercise $32.00 2,250 72,000 0 Sep 02, 2016, 12:37 PM
Schuetz Thomas J. Director Sep 01, 2016 Option Exercise $32.00 33,962 1,086,784 2,250 Sep 02, 2016, 12:37 PM
MCGIRR DAVID W J Director Sep 01, 2016 Option Exercise $32.00 2,250 72,000 0 Sep 02, 2016, 12:37 PM
MCGIRR DAVID W J Director Sep 01, 2016 Option Exercise $32.00 2,729 87,328 2,250 Sep 02, 2016, 12:37 PM
Hillan Kenneth J. Director Sep 01, 2016 Option Exercise $32.00 2,250 72,000 0 Sep 02, 2016, 12:35 PM
Hillan Kenneth J. Director Sep 01, 2016 Option Exercise $32.00 1,237 39,584 2,250 Sep 02, 2016, 12:35 PM
HASTINGS PAUL J Director Sep 01, 2016 Option Exercise $32.00 2,250 72,000 0 Sep 02, 2016, 12:34 PM
HASTINGS PAUL J Director Sep 01, 2016 Option Exercise $32.00 2,495 79,840 2,250 Sep 02, 2016, 12:34 PM
Butler John P. Director Sep 01, 2016 Option Exercise $32.00 2,250 72,000 0 Sep 02, 2016, 12:33 PM
Butler John P. Director Sep 01, 2016 Option Exercise $32.00 2,849 91,168 2,250 Sep 02, 2016, 12:33 PM
Stahl Wilhelm SVP, Chief Technology Officer Sep 01, 2016 Option Exercise $32.00 14,167 453,344 0 Sep 02, 2016, 12:32 PM
Stahl Wilhelm SVP, Chief Technology Officer Sep 01, 2016 Option Exercise $32.00 3,479 111,328 14,167 Sep 02, 2016, 12:32 PM
Orwin John A President & CEO Sep 01, 2016 Option Exercise $32.00 55,000 1,760,000 0 Sep 02, 2016, 12:31 PM
Orwin John A President & CEO Sep 01, 2016 Option Exercise $32.00 10,142 324,544 55,000 Sep 02, 2016, 12:31 PM
Montgomery Monte Chief Accounting Officer Sep 01, 2016 Option Exercise $32.00 13,200 422,400 0 Sep 02, 2016, 12:30 PM
Montgomery Monte Chief Accounting Officer Sep 01, 2016 Option Exercise $32.00 2,066 66,112 13,200 Sep 02, 2016, 12:30 PM
Krasnow Ronald A. See Remarks Sep 01, 2016 Option Exercise $32.00 14,167 453,344 0 Sep 02, 2016, 12:29 PM
Krasnow Ronald A. See Remarks Sep 01, 2016 Option Exercise $32.00 3,479 111,328 14,167 Sep 02, 2016, 12:29 PM
Harrison Stephen D SVP & Chief Scientific Officer Sep 01, 2016 Option Exercise $32.00 16,042 513,344 0 Sep 02, 2016, 12:28 PM
Harrison Stephen D SVP & Chief Scientific Officer Sep 01, 2016 Option Exercise $32.00 5,969 191,008 16,042 Sep 02, 2016, 12:28 PM
Garland J. Scott SVP & Chief Commercial Officer Sep 01, 2016 Option Exercise $32.00 16,042 513,344 0 Sep 02, 2016, 12:27 PM
Garland J. Scott SVP & Chief Commercial Officer Sep 01, 2016 Option Exercise $32.00 2,470 79,040 16,042 Sep 02, 2016, 12:27 PM
Corbett Mary Senior VP, Human Resources Sep 01, 2016 Option Exercise $32.00 14,167 453,344 0 Sep 02, 2016, 12:26 PM
Corbett Mary Senior VP, Human Resources Sep 01, 2016 Option Exercise $32.00 6,080 194,560 14,167 Sep 02, 2016, 12:26 PM
Berman Lance Chief Medical Officer and SVP Sep 01, 2016 Option Exercise $32.00 20,355 651,360 0 Sep 02, 2016, 12:26 PM
Berman Lance Chief Medical Officer and SVP Sep 01, 2016 Option Exercise $32.00 4,922 157,504 20,355 Sep 02, 2016, 12:26 PM
BALL KRISTINE M Chief Financial Officer & SVP Sep 01, 2016 Option Exercise $32.00 20,355 651,360 0 Sep 02, 2016, 12:25 PM
BALL KRISTINE M Chief Financial Officer & SVP Sep 01, 2016 Option Exercise $32.00 11,922 381,504 20,355 Sep 02, 2016, 12:25 PM
Montgomery Monte Chief Accounting Officer Aug 16, 2016 Sale $31.92 510 16,279 12,539 Aug 18, 2016, 06:47 PM
DONDERO JAMES D 10% Owner Aug 17, 2016 Buy $31.92 500 15,960 128,500 Aug 18, 2016, 05:23 PM
Krasnow Ronald A. See Remarks Aug 15, 2016 Option Exercise $31.89 1,034 32,974 14,729 Aug 17, 2016, 04:26 PM
Harrison Stephen D SVP & Chief Scientific Officer Aug 15, 2016 Option Exercise $31.89 705 22,482 17,844 Aug 17, 2016, 04:25 PM
Garland J. Scott SVP & Chief Commercial Officer Aug 15, 2016 Option Exercise $31.89 705 22,482 14,345 Aug 17, 2016, 04:24 PM
Corbett Mary Senior VP, Human Resources Aug 15, 2016 Option Exercise $31.89 1,034 32,974 17,330 Aug 17, 2016, 04:23 PM
Berman Lance Chief Medical Officer and SVP Aug 15, 2016 Option Exercise $31.89 1,480 47,197 21,110 Aug 17, 2016, 04:22 PM
BALL KRISTINE M Chief Financial Officer & SVP Aug 15, 2016 Option Exercise $31.89 1,480 47,197 28,110 Aug 17, 2016, 04:21 PM
Stahl Wilhelm SVP, Chief Technology Officer Aug 15, 2016 Option Exercise $31.89 1,034 32,974 14,729 Aug 17, 2016, 04:20 PM
Orwin John A President & CEO Aug 15, 2016 Option Exercise $31.89 3,994 127,369 53,892 Aug 17, 2016, 04:20 PM
DONDERO JAMES D 10% Owner Aug 11, 2016 Sale $31.96 37,000 1,182,520 128,000 Aug 15, 2016, 06:21 PM
ORBIMED ADVISORS LLC 10% Owner Jul 25, 2016 Sale $31.98 343,600 10,988,328 3,356,400 Jul 26, 2016, 06:04 PM
ORBIMED ADVISORS LLC 10% Owner Jul 22, 2016 Sale $32.00 3,700,000 118,400,000 3,700,000 Jul 26, 2016, 06:04 PM
Torley Helen Director Jun 07, 2016 Sale $19.32 1,013 19,570 1,237 Jun 08, 2016, 05:23 PM
SPIEGELMAN DANIEL K Director Jun 07, 2016 Sale $19.31 1,013 19,562 1,237 Jun 08, 2016, 05:22 PM
Hillan Kenneth J. Director Jun 07, 2016 Sale $19.31 1,013 19,563 1,237 Jun 08, 2016, 05:21 PM
Butler John P. Director Jun 07, 2016 Sale $19.32 1,013 19,570 2,849 Jun 08, 2016, 05:19 PM
HASTINGS PAUL J Director Jun 07, 2016 Sale $19.32 1,013 19,573 2,495 Jun 08, 2016, 05:18 PM
MCGIRR DAVID W J Director Jun 07, 2016 Sale $19.34 1,013 19,588 2,729 Jun 08, 2016, 05:17 PM
Krasnow Ronald A. See Remarks Jun 03, 2016 Option Exercise $19.96 548 10,938 15,763 Jun 07, 2016, 06:53 PM
Stahl Wilhelm SVP, Chief Technology Officer Jun 03, 2016 Option Exercise $19.96 548 10,938 15,763 Jun 07, 2016, 06:51 PM
Garland J. Scott SVP & Chief Commercial Officer Jun 03, 2016 Option Exercise $19.96 783 15,629 15,050 Jun 07, 2016, 06:50 PM
Harrison Stephen D SVP & Chief Scientific Officer Jun 03, 2016 Option Exercise $19.96 783 15,629 18,549 Jun 07, 2016, 06:49 PM
Berman Lance Chief Medical Officer and SVP Jun 03, 2016 Option Exercise $19.96 783 15,629 22,590 Jun 07, 2016, 06:48 PM
Corbett Mary Senior VP, Human Resources Jun 03, 2016 Option Exercise $19.96 548 10,938 18,364 Jun 07, 2016, 06:48 PM
Orwin John A President & CEO Jun 03, 2016 Option Exercise $19.96 2,114 42,195 57,886 Jun 07, 2016, 06:47 PM
BALL KRISTINE M Chief Financial Officer & SVP Jun 03, 2016 Option Exercise $19.96 783 15,629 29,590 Jun 07, 2016, 06:46 PM
Harrison Stephen D SVP & Chief Scientific Officer Feb 29, 2016 Option Exercise $11.27 2,218 24,999 17,249 Mar 16, 2016, 07:29 PM
Corbett Mary Senior VP, Human Resources Feb 29, 2016 Option Exercise $11.27 1,274 14,359 17,454 Mar 16, 2016, 07:28 PM
BALL KRISTINE M Chief Financial Officer & SVP Mar 16, 2016 Buy $12.15 7,000 85,050 28,290 Mar 16, 2016, 07:27 PM
Schuetz Thomas J. Director Mar 15, 2016 Buy $13.39 30,000 401,832 33,962 Mar 16, 2016, 07:26 PM
Stahl Wilhelm SVP, Chief Technology Officer Dec 31, 2015 Option Exercise $3.96 20,000 79,200 34,853 Jan 04, 2016, 05:27 PM
Stahl Wilhelm SVP, Chief Technology Officer Dec 31, 2015 Sale $28.53 20,000 570,558 14,853 Jan 04, 2016, 05:27 PM
ORBIMED ADVISORS LLC 10% Owner Dec 23, 2015 Sale $27.18 100,000 2,717,564 7,452,058 Dec 23, 2015, 05:06 PM
ORBIMED ADVISORS LLC 10% Owner Dec 22, 2015 Sale $26.55 150,000 3,982,837 7,538,630 Dec 23, 2015, 05:06 PM
ORBIMED ADVISORS LLC 10% Owner Dec 21, 2015 Sale $27.55 250,000 6,887,612 7,664,171 Dec 23, 2015, 05:06 PM
Orwin John A President & CEO Dec 07, 2015 Option Exercise $7.40 10,000 74,000 69,375 Dec 09, 2015, 08:24 PM
Orwin John A President & CEO Dec 07, 2015 Sale $28.28 15,000 424,132 62,554 Dec 09, 2015, 08:24 PM
Berman Lance Chief Medical Officer and SVP Dec 09, 2015 Option Exercise $7.40 750 5,550 22,040 Dec 09, 2015, 08:23 PM
Berman Lance Chief Medical Officer and SVP Dec 07, 2015 Option Exercise $4.51 30,000 135,157 51,290 Dec 09, 2015, 08:23 PM
Berman Lance Chief Medical Officer and SVP Dec 07, 2015 Sale $29.78 30,000 893,400 21,290 Dec 09, 2015, 08:23 PM
Berman Lance Chief Medical Officer and SVP Dec 09, 2015 Sale $29.50 750 22,125 21,290 Dec 09, 2015, 08:23 PM
Orwin John A President & CEO Dec 04, 2015 Option Exercise $7.40 20,000 148,000 79,375 Dec 04, 2015, 05:50 PM
Orwin John A President & CEO Dec 02, 2015 Option Exercise $7.40 20,000 148,000 79,375 Dec 04, 2015, 05:50 PM
Orwin John A President & CEO Dec 02, 2015 Sale $25.00 20,000 500,000 59,375 Dec 04, 2015, 05:50 PM
Orwin John A President & CEO Dec 04, 2015 Sale $25.00 20,000 500,000 59,375 Dec 04, 2015, 05:50 PM
ORBIMED ADVISORS LLC 10% Owner Oct 22, 2015 Buy $12.56 500,000 6,280,165 7,900,000 Oct 22, 2015, 06:00 PM
BALL KRISTINE M Chief Financial Officer & SVP Sep 02, 2015 Sale $22.96 646 14,832 15,040 Sep 03, 2015, 06:21 PM
Krasnow Ronald A. See Remarks Aug 17, 2015 Sale $24.75 522 12,922 10,478 Aug 19, 2015, 07:42 PM
Corbett Mary Senior VP, Human Resources Aug 17, 2015 Sale $24.72 522 12,906 10,479 Aug 19, 2015, 07:41 PM
Berman Lance Chief Medical Officer and SVP Aug 17, 2015 Sale $24.77 710 17,586 15,040 Aug 19, 2015, 07:41 PM
BALL KRISTINE M Chief Financial Officer & SVP Aug 17, 2015 Sale $24.78 710 17,597 15,040 Aug 19, 2015, 07:40 PM
Orwin John A President & CEO Aug 17, 2015 Sale $24.84 5,000 124,183 44,866 Aug 19, 2015, 07:40 PM
Stahl Wilhelm SVP, Chief Technology Officer Aug 17, 2015 Sale $24.70 522 12,894 10,478 Aug 19, 2015, 07:39 PM
Lockey Claire See Remarks Aug 17, 2015 Sale $24.69 522 12,888 10,478 Aug 19, 2015, 07:39 PM
Orwin John A President & CEO Jul 31, 2015 Option Exercise $7.40 5,000 37,000 35,000 Aug 03, 2015, 08:43 PM
Orwin John A President & CEO Jul 30, 2015 Option Exercise $7.40 20,000 148,000 50,000 Aug 03, 2015, 08:43 PM
Orwin John A President & CEO Jul 31, 2015 Sale $33.52 10,000 335,225 25,200 Aug 03, 2015, 08:43 PM
Orwin John A President & CEO Jul 30, 2015 Sale $33.58 20,000 671,573 30,200 Aug 03, 2015, 08:43 PM
MCGIRR DAVID W J Director Jun 11, 2015 Sale $34.67 1,220 42,300 3,742 Jun 15, 2015, 06:42 PM
HASTINGS PAUL J Director Jun 11, 2015 Sale $34.63 1,454 50,359 3,508 Jun 15, 2015, 06:41 PM
Butler John P. Director Jun 11, 2015 Sale $34.62 1,100 38,087 3,862 Jun 15, 2015, 06:40 PM
Schuetz Thomas J. Director Jun 11, 2015 Sale $34.57 1,000 34,571 3,962 Jun 15, 2015, 06:39 PM
Orwin John A President & CEO May 29, 2015 Option Exercise $7.40 20,000 148,000 55,000 Jun 02, 2015, 08:24 PM
Orwin John A President & CEO Jun 01, 2015 Option Exercise $7.40 8,555 63,307 43,555 Jun 02, 2015, 08:24 PM
Orwin John A President & CEO May 29, 2015 Sale $36.55 20,000 731,001 40,306 Jun 02, 2015, 08:24 PM
Orwin John A President & CEO Jun 01, 2015 Sale $36.23 13,555 491,148 35,204 Jun 02, 2015, 08:24 PM
ORBIMED ADVISORS LLC 10% Owner May 18, 2015 Sale $34.13 1,457,551 49,746,217 7,400,000 May 20, 2015, 08:30 PM
VEITINGER KLAUS R DR Director May 11, 2015 Option Exercise $3.96 5,834 23,103 8,546 May 13, 2015, 07:00 PM
VEITINGER KLAUS R DR Director May 11, 2015 Sale $36.06 5,834 210,387 2,712 May 13, 2015, 07:00 PM
VEITINGER KLAUS R DR Director Apr 10, 2015 Option Exercise $3.96 5,832 23,095 8,544 Apr 13, 2015, 06:09 PM
VEITINGER KLAUS R DR Director Apr 10, 2015 Sale $35.35 5,832 206,179 2,712 Apr 13, 2015, 06:09 PM
VEITINGER KLAUS R DR Director Mar 10, 2015 Option Exercise $4.35 5,834 25,401 8,546 Mar 12, 2015, 06:21 PM
VEITINGER KLAUS R DR Director Mar 10, 2015 Sale $38.67 5,834 225,594 2,712 Mar 12, 2015, 06:21 PM
Lockey Claire See Remarks Mar 04, 2015 Option Exercise $4.57 10,000 45,685 15,500 Mar 06, 2015, 07:19 PM
Lockey Claire See Remarks Mar 04, 2015 Sale $40.00 10,000 400,000 5,500 Mar 06, 2015, 07:19 PM
BALL KRISTINE M Chief Financial Officer & SVP Mar 05, 2015 Option Exercise $3.96 3,000 11,880 10,500 Mar 05, 2015, 08:24 PM
BALL KRISTINE M Chief Financial Officer & SVP Mar 05, 2015 Sale $41.00 3,000 123,000 7,500 Mar 05, 2015, 08:24 PM
BALL KRISTINE M Chief Financial Officer & SVP Mar 03, 2015 Sale $38.80 519 20,137 7,500 Mar 05, 2015, 08:24 PM
Krasnow Ronald A. See Remarks Feb 27, 2015 Sale $39.00 348 13,572 5,500 Feb 27, 2015, 08:55 PM
Krasnow Ronald A. See Remarks Feb 26, 2015 Sale $39.00 5,000 195,000 5,848 Feb 27, 2015, 08:55 PM
Krasnow Ronald A. See Remarks Feb 25, 2015 Sale $39.00 5,000 195,000 10,848 Feb 27, 2015, 08:55 PM
Berman Lance Chief Medical Officer and SVP Feb 24, 2015 Option Exercise $5.23 5,000 26,130 12,500 Feb 25, 2015, 06:33 PM
Berman Lance Chief Medical Officer and SVP Feb 24, 2015 Sale $38.19 5,000 190,949 9,800 Feb 25, 2015, 06:33 PM
Krasnow Ronald A. See Remarks Feb 23, 2015 Sale $39.00 5,000 195,000 20,848 Feb 25, 2015, 11:44 AM
Krasnow Ronald A. See Remarks Feb 24, 2015 Sale $39.00 5,000 195,000 15,848 Feb 25, 2015, 11:44 AM
VEITINGER KLAUS R DR Director Feb 10, 2015 Option Exercise $4.65 5,834 27,128 8,546 Feb 10, 2015, 09:06 PM
VEITINGER KLAUS R DR Director Feb 10, 2015 Sale $32.12 5,834 187,359 2,812 Feb 10, 2015, 09:06 PM
Krasnow Ronald A. See Remarks Jan 21, 2015 Option Exercise $3.78 55,000 208,103 80,848 Jan 23, 2015, 09:45 PM
Krasnow Ronald A. See Remarks Jan 21, 2015 Sale $35.00 55,000 1,925,000 25,848 Jan 23, 2015, 09:45 PM
BALL KRISTINE M Chief Financial Officer & SVP Jan 21, 2015 Option Exercise $3.96 3,000 11,880 10,500 Jan 23, 2015, 09:44 PM
BALL KRISTINE M Chief Financial Officer & SVP Jan 21, 2015 Sale $36.00 3,000 108,000 7,500 Jan 23, 2015, 09:44 PM
Lockey Claire See Remarks Jan 21, 2015 Option Exercise $4.65 5,000 23,250 10,500 Jan 23, 2015, 09:43 PM
Lockey Claire See Remarks Jan 21, 2015 Sale $35.00 5,000 175,000 5,500 Jan 23, 2015, 09:43 PM
Krasnow Ronald A. See Remarks Jan 14, 2015 Option Exercise $2.76 5,000 13,800 30,848 Jan 16, 2015, 07:43 PM
Krasnow Ronald A. See Remarks Jan 14, 2015 Sale $33.58 5,000 167,895 26,928 Jan 16, 2015, 07:43 PM
VEITINGER KLAUS R DR Director Jan 12, 2015 Option Exercise $4.65 5,834 27,128 8,546 Jan 14, 2015, 11:15 AM
VEITINGER KLAUS R DR Director Jan 12, 2015 Sale $32.33 5,834 188,589 4,160 Jan 14, 2015, 11:15 AM
VEITINGER KLAUS R DR Director Dec 12, 2014 Option Exercise $4.65 9,852 45,812 12,564 Dec 12, 2014, 07:11 PM
VEITINGER KLAUS R DR Director Dec 10, 2014 Option Exercise $4.65 4,167 19,377 6,879 Dec 12, 2014, 07:11 PM
VEITINGER KLAUS R DR Director Dec 11, 2014 Option Exercise $4.65 150 698 2,862 Dec 12, 2014, 07:11 PM
VEITINGER KLAUS R DR Director Dec 11, 2014 Sale $32.50 150 4,875 2,712 Dec 12, 2014, 07:11 PM
VEITINGER KLAUS R DR Director Dec 12, 2014 Sale $32.50 9,852 320,190 2,712 Dec 12, 2014, 07:11 PM
VEITINGER KLAUS R DR Director Dec 10, 2014 Sale $31.35 4,167 130,617 6,079 Dec 12, 2014, 07:11 PM
5AM Partners III, LLC 10% Owner Dec 09, 2014 Sale $30.04 589,637 17,712,696 1,843,243 Dec 11, 2014, 04:55 PM
Lockey Claire See Remarks Dec 09, 2014 Option Exercise $4.65 8,000 37,200 13,500 Dec 10, 2014, 08:29 PM
Lockey Claire See Remarks Dec 09, 2014 Sale $30.00 8,000 240,000 5,500 Dec 10, 2014, 08:29 PM
Berman Lance Chief Medical Officer and SVP Nov 28, 2014 Option Exercise $4.50 5,000 22,504 12,500 Dec 02, 2014, 07:02 PM
Berman Lance Chief Medical Officer and SVP Nov 28, 2014 Sale $25.00 5,000 125,000 7,500 Dec 02, 2014, 07:02 PM
Berman Lance Chief Medical Officer and SVP Nov 25, 2014 Option Exercise $4.56 15,000 68,399 22,500 Nov 26, 2014, 04:33 PM
Berman Lance Chief Medical Officer and SVP Nov 24, 2014 Option Exercise $3.96 15,000 59,400 22,500 Nov 26, 2014, 04:33 PM
Berman Lance Chief Medical Officer and SVP Nov 25, 2014 Sale $25.00 15,000 375,000 7,500 Nov 26, 2014, 04:33 PM
Berman Lance Chief Medical Officer and SVP Nov 24, 2014 Sale $25.00 15,000 375,000 7,500 Nov 26, 2014, 04:33 PM
VEITINGER KLAUS R DR Director Nov 20, 2014 Option Exercise $4.65 3,334 15,503 6,046 Nov 24, 2014, 05:48 PM
VEITINGER KLAUS R DR Director Nov 20, 2014 Sale $22.50 3,334 75,015 2,712 Nov 24, 2014, 05:48 PM
VEITINGER KLAUS R DR Director Nov 10, 2014 Option Exercise $4.65 2,500 11,625 5,212 Nov 12, 2014, 04:29 PM
VEITINGER KLAUS R DR Director Nov 10, 2014 Sale $20.06 2,500 50,144 2,712 Nov 12, 2014, 04:29 PM
VEITINGER KLAUS R DR Director Oct 10, 2014 Option Exercise $4.65 2,500 11,625 5,212 Oct 15, 2014, 04:19 PM
VEITINGER KLAUS R DR Director Oct 10, 2014 Sale $19.34 2,500 48,343 2,812 Oct 15, 2014, 04:19 PM
Berman Lance Chief Medical Officer and SVP Sep 24, 2014 Option Exercise $4.41 5,000 22,033 12,500 Sep 25, 2014, 08:01 PM
Berman Lance Chief Medical Officer and SVP Sep 24, 2014 Sale $22.00 5,000 110,000 7,500 Sep 25, 2014, 08:01 PM
ORBIMED ADVISORS LLC 10% Owner Sep 17, 2014 Sale $25.07 49,000 1,228,430 8,857,551 Sep 18, 2014, 05:20 PM
ORBIMED ADVISORS LLC 10% Owner Sep 16, 2014 Sale $25.49 45,000 1,146,836 8,909,151 Sep 18, 2014, 05:20 PM
5AM Partners II, LLC 10% Owner Sep 16, 2014 Sale $26.03 612,540 15,944,417 1,269,398 Sep 17, 2014, 02:48 PM
VEITINGER KLAUS R DR Director Sep 10, 2014 Option Exercise $4.65 4,167 19,377 6,879 Sep 11, 2014, 07:38 PM
VEITINGER KLAUS R DR Director Sep 10, 2014 Sale $23.00 4,167 95,851 2,712 Sep 11, 2014, 07:38 PM
Stahl Wilhelm SVP, Pharmaceutical Operations Aug 29, 2014 Option Exercise $4.21 15,785 66,520 21,285 Sep 03, 2014, 05:56 PM
Stahl Wilhelm SVP, Pharmaceutical Operations Aug 29, 2014 Sale $25.29 15,785 399,253 5,500 Sep 03, 2014, 05:56 PM
5AM Partners II, LLC 10% Owner Aug 26, 2014 Sale $26.53 96,310 2,555,104 1,858,686 Aug 27, 2014, 04:49 PM
5AM Partners II, LLC 10% Owner Aug 25, 2014 Sale $26.50 336,690 8,922,285 1,951,340 Aug 27, 2014, 04:49 PM
Berman Lance Chief Medical Officer and SVP Aug 22, 2014 Option Exercise $4.37 15,000 65,568 22,500 Aug 26, 2014, 07:52 PM
Berman Lance Chief Medical Officer and SVP Aug 25, 2014 Option Exercise $7.40 5,000 37,000 12,500 Aug 26, 2014, 07:52 PM
Berman Lance Chief Medical Officer and SVP Aug 22, 2014 Sale $25.69 15,000 385,343 7,500 Aug 26, 2014, 07:52 PM
Berman Lance Chief Medical Officer and SVP Aug 25, 2014 Sale $26.48 5,000 132,379 7,500 Aug 26, 2014, 07:52 PM
ORBIMED ADVISORS LLC 10% Owner Aug 15, 2014 Sale $26.35 990,000 26,086,500 8,951,551 Aug 19, 2014, 08:22 PM
VEITINGER KLAUS R DR Director Aug 11, 2014 Option Exercise $4.65 4,167 19,377 6,879 Aug 12, 2014, 07:17 PM
VEITINGER KLAUS R DR Director Aug 11, 2014 Sale $27.73 4,167 115,563 2,712 Aug 12, 2014, 07:17 PM
Stahl Wilhelm SVP, Pharmaceutical Operations Aug 08, 2014 Option Exercise $3.96 49,300 195,228 49,300 Aug 12, 2014, 07:16 PM
Stahl Wilhelm SVP, Pharmaceutical Operations Aug 08, 2014 Sale $25.09 49,300 1,237,085 0 Aug 12, 2014, 07:16 PM
Lockey Claire See Remarks Aug 08, 2014 Option Exercise $4.65 10,000 46,500 10,000 Aug 12, 2014, 07:16 PM
Lockey Claire See Remarks Aug 08, 2014 Sale $26.50 10,000 265,000 6,000 Aug 12, 2014, 07:16 PM
Berman Lance Chief Medical Officer and SVP Jul 24, 2014 Option Exercise $3.96 15,000 59,400 15,000 Jul 24, 2014, 07:12 PM
Berman Lance Chief Medical Officer and SVP Jul 22, 2014 Option Exercise $3.96 15,000 59,400 15,000 Jul 24, 2014, 07:12 PM
Berman Lance Chief Medical Officer and SVP Jul 23, 2014 Option Exercise $3.96 15,000 59,400 15,000 Jul 24, 2014, 07:12 PM
Berman Lance Chief Medical Officer and SVP Jul 23, 2014 Sale $24.24 15,000 363,622 400 Jul 24, 2014, 07:12 PM
Berman Lance Chief Medical Officer and SVP Jul 24, 2014 Sale $23.86 15,000 357,896 1,472 Jul 24, 2014, 07:12 PM
Berman Lance Chief Medical Officer and SVP Jul 22, 2014 Sale $23.67 15,000 354,993 0 Jul 24, 2014, 07:12 PM
VEITINGER KLAUS R DR Director Jul 10, 2014 Option Exercise $4.65 4,167 19,377 6,879 Jul 11, 2014, 06:23 PM
VEITINGER KLAUS R DR Director Jul 10, 2014 Sale $23.12 4,167 96,354 2,712 Jul 11, 2014, 06:23 PM
New Leaf Ventures I, L.P. Director Nov 20, 2013 Option Exercise $11.00 21,691 238,601 1,928,912 Nov 20, 2013, 09:51 PM
New Leaf Ventures I, L.P. Director Nov 20, 2013 Option Exercise $9.18 25,977 238,594 1,950,603 Nov 20, 2013, 09:51 PM
New Leaf Ventures I, L.P. Director Nov 20, 2013 Buy $11.00 185,978 2,045,758 2,114,890 Nov 20, 2013, 09:51 PM
HUNT RONALD Director Nov 20, 2013 Option Exercise $11.00 21,691 238,601 1,928,912 Nov 20, 2013, 09:50 PM
HUNT RONALD Director Nov 20, 2013 Option Exercise $9.18 25,977 238,594 1,950,603 Nov 20, 2013, 09:50 PM
HUNT RONALD Director Nov 20, 2013 Buy $11.00 185,978 2,045,758 2,114,890 Nov 20, 2013, 09:50 PM
SILVERSTEIN JONATHAN Director Nov 20, 2013 Option Exercise $11.00 27,282 300,102 9,229,359 Nov 20, 2013, 07:31 PM
SILVERSTEIN JONATHAN Director Nov 20, 2013 Option Exercise $0.17 1,744,711 296,601 9,234,475 Nov 20, 2013, 07:31 PM
SILVERSTEIN JONATHAN Director Nov 20, 2013 Buy $11.00 712,192 7,834,112 9,941,551 Nov 20, 2013, 07:31 PM
ORBIMED ADVISORS LLC 10% Owner Nov 20, 2013 Option Exercise $11.00 27,282 300,102 9,229,359 Nov 20, 2013, 07:23 PM
ORBIMED ADVISORS LLC 10% Owner Nov 20, 2013 Option Exercise $0.17 1,744,711 296,601 9,234,475 Nov 20, 2013, 07:23 PM
ORBIMED ADVISORS LLC 10% Owner Nov 20, 2013 Buy $11.00 712,192 7,834,112 9,941,551 Nov 20, 2013, 07:23 PM
ROCKLAGE SCOTT M Director Nov 20, 2013 Option Exercise $11.00 221 2,431 52,952 Nov 20, 2013, 07:18 PM
ROCKLAGE SCOTT M Director Nov 20, 2013 Option Exercise $0.17 14,024 2,384 52,994 Nov 20, 2013, 07:18 PM
ROCKLAGE SCOTT M Director Nov 20, 2013 Buy $11.00 9,364 103,004 62,316 Nov 20, 2013, 07:18 PM
ROCKLAGE SCOTT M Director Nov 20, 2013 Option Exercise $11.00 42,160 463,760 2,275,248 Nov 20, 2013, 07:13 PM
ROCKLAGE SCOTT M Director Nov 20, 2013 Option Exercise $0.68 677,742 462,439 2,275,517 Nov 20, 2013, 07:13 PM
ROCKLAGE SCOTT M Director Nov 20, 2013 Buy $11.00 363,328 3,996,608 2,418,066 Nov 20, 2013, 07:13 PM
5AM Partners III, LLC 10% Owner Nov 20, 2013 Option Exercise $11.00 8,731 96,041 2,054,738 Nov 20, 2013, 07:13 PM
5AM Partners III, LLC 10% Owner Nov 20, 2013 Option Exercise $0.17 558,220 94,897 2,056,334 Nov 20, 2013, 07:13 PM
5AM Partners III, LLC 10% Owner Nov 20, 2013 Buy $11.00 372,692 4,099,612 2,418,066 Nov 20, 2013, 07:13 PM
Orwin John A President & CEO Nov 20, 2013 Buy $11.00 15,000 165,000 15,000 Nov 20, 2013, 07:10 PM
5AM Partners II, LLC 10% Owner Nov 20, 2013 Option Exercise $11.00 33,650 370,150 2,275,248 Nov 20, 2013, 05:45 PM
5AM Partners II, LLC 10% Owner Nov 20, 2013 Option Exercise $2.77 133,546 369,926 2,275,517 Nov 20, 2013, 05:45 PM

Desktop Version

Owner Relationship Date Transaction Value($)
Torley Helen Director Sep 01, 2016 Option Exercise 72,000
Torley Helen Director Sep 01, 2016 Option Exercise 39,584
SPIEGELMAN DANIEL K Director Sep 01, 2016 Option Exercise 72,000
SPIEGELMAN DANIEL K Director Sep 01, 2016 Option Exercise 39,584
Schuetz Thomas J. Director Sep 01, 2016 Option Exercise 72,000
Schuetz Thomas J. Director Sep 01, 2016 Option Exercise 1,086,784
MCGIRR DAVID W J Director Sep 01, 2016 Option Exercise 72,000
MCGIRR DAVID W J Director Sep 01, 2016 Option Exercise 87,328
Hillan Kenneth J. Director Sep 01, 2016 Option Exercise 72,000
Hillan Kenneth J. Director Sep 01, 2016 Option Exercise 39,584
HASTINGS PAUL J Director Sep 01, 2016 Option Exercise 72,000
HASTINGS PAUL J Director Sep 01, 2016 Option Exercise 79,840
Butler John P. Director Sep 01, 2016 Option Exercise 72,000
Butler John P. Director Sep 01, 2016 Option Exercise 91,168
Stahl Wilhelm SVP, Chief Technology Officer Sep 01, 2016 Option Exercise 453,344
Stahl Wilhelm SVP, Chief Technology Officer Sep 01, 2016 Option Exercise 111,328
Orwin John A President & CEO Sep 01, 2016 Option Exercise 1,760,000
Orwin John A President & CEO Sep 01, 2016 Option Exercise 324,544
Montgomery Monte Chief Accounting Officer Sep 01, 2016 Option Exercise 422,400
Montgomery Monte Chief Accounting Officer Sep 01, 2016 Option Exercise 66,112
Krasnow Ronald A. See Remarks Sep 01, 2016 Option Exercise 453,344
Krasnow Ronald A. See Remarks Sep 01, 2016 Option Exercise 111,328
Harrison Stephen D SVP & Chief Scientific Officer Sep 01, 2016 Option Exercise 513,344
Harrison Stephen D SVP & Chief Scientific Officer Sep 01, 2016 Option Exercise 191,008
Garland J. Scott SVP & Chief Commercial Officer Sep 01, 2016 Option Exercise 513,344
Garland J. Scott SVP & Chief Commercial Officer Sep 01, 2016 Option Exercise 79,040
Corbett Mary Senior VP, Human Resources Sep 01, 2016 Option Exercise 453,344
Corbett Mary Senior VP, Human Resources Sep 01, 2016 Option Exercise 194,560
Berman Lance Chief Medical Officer and SVP Sep 01, 2016 Option Exercise 651,360
Berman Lance Chief Medical Officer and SVP Sep 01, 2016 Option Exercise 157,504
BALL KRISTINE M Chief Financial Officer & SVP Sep 01, 2016 Option Exercise 651,360
BALL KRISTINE M Chief Financial Officer & SVP Sep 01, 2016 Option Exercise 381,504
Montgomery Monte Chief Accounting Officer Aug 16, 2016 Sale 16,279
DONDERO JAMES D 10% Owner Aug 17, 2016 Buy 15,960
Krasnow Ronald A. See Remarks Aug 15, 2016 Option Exercise 32,974
Harrison Stephen D SVP & Chief Scientific Officer Aug 15, 2016 Option Exercise 22,482
Garland J. Scott SVP & Chief Commercial Officer Aug 15, 2016 Option Exercise 22,482
Corbett Mary Senior VP, Human Resources Aug 15, 2016 Option Exercise 32,974
Berman Lance Chief Medical Officer and SVP Aug 15, 2016 Option Exercise 47,197
BALL KRISTINE M Chief Financial Officer & SVP Aug 15, 2016 Option Exercise 47,197
Stahl Wilhelm SVP, Chief Technology Officer Aug 15, 2016 Option Exercise 32,974
Orwin John A President & CEO Aug 15, 2016 Option Exercise 127,369
DONDERO JAMES D 10% Owner Aug 11, 2016 Sale 1,182,520
ORBIMED ADVISORS LLC 10% Owner Jul 25, 2016 Sale 10,988,328
ORBIMED ADVISORS LLC 10% Owner Jul 22, 2016 Sale 118,400,000
Torley Helen Director Jun 07, 2016 Sale 19,570
SPIEGELMAN DANIEL K Director Jun 07, 2016 Sale 19,562
Hillan Kenneth J. Director Jun 07, 2016 Sale 19,563
Butler John P. Director Jun 07, 2016 Sale 19,570
HASTINGS PAUL J Director Jun 07, 2016 Sale 19,573
MCGIRR DAVID W J Director Jun 07, 2016 Sale 19,588
Krasnow Ronald A. See Remarks Jun 03, 2016 Option Exercise 10,938
Stahl Wilhelm SVP, Chief Technology Officer Jun 03, 2016 Option Exercise 10,938
Garland J. Scott SVP & Chief Commercial Officer Jun 03, 2016 Option Exercise 15,629
Harrison Stephen D SVP & Chief Scientific Officer Jun 03, 2016 Option Exercise 15,629
Berman Lance Chief Medical Officer and SVP Jun 03, 2016 Option Exercise 15,629
Corbett Mary Senior VP, Human Resources Jun 03, 2016 Option Exercise 10,938
Orwin John A President & CEO Jun 03, 2016 Option Exercise 42,195
BALL KRISTINE M Chief Financial Officer & SVP Jun 03, 2016 Option Exercise 15,629
Harrison Stephen D SVP & Chief Scientific Officer Feb 29, 2016 Option Exercise 24,999
Corbett Mary Senior VP, Human Resources Feb 29, 2016 Option Exercise 14,359
BALL KRISTINE M Chief Financial Officer & SVP Mar 16, 2016 Buy 85,050
Schuetz Thomas J. Director Mar 15, 2016 Buy 401,832
Stahl Wilhelm SVP, Chief Technology Officer Dec 31, 2015 Option Exercise 79,200
Stahl Wilhelm SVP, Chief Technology Officer Dec 31, 2015 Sale 570,558
ORBIMED ADVISORS LLC 10% Owner Dec 23, 2015 Sale 2,717,564
ORBIMED ADVISORS LLC 10% Owner Dec 22, 2015 Sale 3,982,837
ORBIMED ADVISORS LLC 10% Owner Dec 21, 2015 Sale 6,887,612
Orwin John A President & CEO Dec 07, 2015 Option Exercise 74,000
Orwin John A President & CEO Dec 07, 2015 Sale 424,132
Berman Lance Chief Medical Officer and SVP Dec 09, 2015 Option Exercise 5,550
Berman Lance Chief Medical Officer and SVP Dec 07, 2015 Option Exercise 135,157
Berman Lance Chief Medical Officer and SVP Dec 07, 2015 Sale 893,400
Berman Lance Chief Medical Officer and SVP Dec 09, 2015 Sale 22,125
Orwin John A President & CEO Dec 04, 2015 Option Exercise 148,000
Orwin John A President & CEO Dec 02, 2015 Option Exercise 148,000
Orwin John A President & CEO Dec 02, 2015 Sale 500,000
Orwin John A President & CEO Dec 04, 2015 Sale 500,000
ORBIMED ADVISORS LLC 10% Owner Oct 22, 2015 Buy 6,280,165
BALL KRISTINE M Chief Financial Officer & SVP Sep 02, 2015 Sale 14,832
Krasnow Ronald A. See Remarks Aug 17, 2015 Sale 12,922
Corbett Mary Senior VP, Human Resources Aug 17, 2015 Sale 12,906
Berman Lance Chief Medical Officer and SVP Aug 17, 2015 Sale 17,586
BALL KRISTINE M Chief Financial Officer & SVP Aug 17, 2015 Sale 17,597
Orwin John A President & CEO Aug 17, 2015 Sale 124,183
Stahl Wilhelm SVP, Chief Technology Officer Aug 17, 2015 Sale 12,894
Lockey Claire See Remarks Aug 17, 2015 Sale 12,888
Orwin John A President & CEO Jul 31, 2015 Option Exercise 37,000
Orwin John A President & CEO Jul 30, 2015 Option Exercise 148,000
Orwin John A President & CEO Jul 31, 2015 Sale 335,225
Orwin John A President & CEO Jul 30, 2015 Sale 671,573
MCGIRR DAVID W J Director Jun 11, 2015 Sale 42,300
HASTINGS PAUL J Director Jun 11, 2015 Sale 50,359
Butler John P. Director Jun 11, 2015 Sale 38,087
Schuetz Thomas J. Director Jun 11, 2015 Sale 34,571
Orwin John A President & CEO May 29, 2015 Option Exercise 148,000
Orwin John A President & CEO Jun 01, 2015 Option Exercise 63,307
Orwin John A President & CEO May 29, 2015 Sale 731,001
Orwin John A President & CEO Jun 01, 2015 Sale 491,148
ORBIMED ADVISORS LLC 10% Owner May 18, 2015 Sale 49,746,217
VEITINGER KLAUS R DR Director May 11, 2015 Option Exercise 23,103
VEITINGER KLAUS R DR Director May 11, 2015 Sale 210,387
VEITINGER KLAUS R DR Director Apr 10, 2015 Option Exercise 23,095
VEITINGER KLAUS R DR Director Apr 10, 2015 Sale 206,179
VEITINGER KLAUS R DR Director Mar 10, 2015 Option Exercise 25,401
VEITINGER KLAUS R DR Director Mar 10, 2015 Sale 225,594
Lockey Claire See Remarks Mar 04, 2015 Option Exercise 45,685
Lockey Claire See Remarks Mar 04, 2015 Sale 400,000
BALL KRISTINE M Chief Financial Officer & SVP Mar 05, 2015 Option Exercise 11,880
BALL KRISTINE M Chief Financial Officer & SVP Mar 05, 2015 Sale 123,000
BALL KRISTINE M Chief Financial Officer & SVP Mar 03, 2015 Sale 20,137
Krasnow Ronald A. See Remarks Feb 27, 2015 Sale 13,572
Krasnow Ronald A. See Remarks Feb 26, 2015 Sale 195,000
Krasnow Ronald A. See Remarks Feb 25, 2015 Sale 195,000
Berman Lance Chief Medical Officer and SVP Feb 24, 2015 Option Exercise 26,130
Berman Lance Chief Medical Officer and SVP Feb 24, 2015 Sale 190,949
Krasnow Ronald A. See Remarks Feb 23, 2015 Sale 195,000
Krasnow Ronald A. See Remarks Feb 24, 2015 Sale 195,000
VEITINGER KLAUS R DR Director Feb 10, 2015 Option Exercise 27,128
VEITINGER KLAUS R DR Director Feb 10, 2015 Sale 187,359
Krasnow Ronald A. See Remarks Jan 21, 2015 Option Exercise 208,103
Krasnow Ronald A. See Remarks Jan 21, 2015 Sale 1,925,000
BALL KRISTINE M Chief Financial Officer & SVP Jan 21, 2015 Option Exercise 11,880
BALL KRISTINE M Chief Financial Officer & SVP Jan 21, 2015 Sale 108,000
Lockey Claire See Remarks Jan 21, 2015 Option Exercise 23,250
Lockey Claire See Remarks Jan 21, 2015 Sale 175,000
Krasnow Ronald A. See Remarks Jan 14, 2015 Option Exercise 13,800
Krasnow Ronald A. See Remarks Jan 14, 2015 Sale 167,895
VEITINGER KLAUS R DR Director Jan 12, 2015 Option Exercise 27,128
VEITINGER KLAUS R DR Director Jan 12, 2015 Sale 188,589
VEITINGER KLAUS R DR Director Dec 12, 2014 Option Exercise 45,812
VEITINGER KLAUS R DR Director Dec 10, 2014 Option Exercise 19,377
VEITINGER KLAUS R DR Director Dec 11, 2014 Option Exercise 698
VEITINGER KLAUS R DR Director Dec 11, 2014 Sale 4,875
VEITINGER KLAUS R DR Director Dec 12, 2014 Sale 320,190
VEITINGER KLAUS R DR Director Dec 10, 2014 Sale 130,617
5AM Partners III, LLC 10% Owner Dec 09, 2014 Sale 17,712,696
Lockey Claire See Remarks Dec 09, 2014 Option Exercise 37,200
Lockey Claire See Remarks Dec 09, 2014 Sale 240,000
Berman Lance Chief Medical Officer and SVP Nov 28, 2014 Option Exercise 22,504
Berman Lance Chief Medical Officer and SVP Nov 28, 2014 Sale 125,000
Berman Lance Chief Medical Officer and SVP Nov 25, 2014 Option Exercise 68,399
Berman Lance Chief Medical Officer and SVP Nov 24, 2014 Option Exercise 59,400
Berman Lance Chief Medical Officer and SVP Nov 25, 2014 Sale 375,000
Berman Lance Chief Medical Officer and SVP Nov 24, 2014 Sale 375,000
VEITINGER KLAUS R DR Director Nov 20, 2014 Option Exercise 15,503
VEITINGER KLAUS R DR Director Nov 20, 2014 Sale 75,015
VEITINGER KLAUS R DR Director Nov 10, 2014 Option Exercise 11,625
VEITINGER KLAUS R DR Director Nov 10, 2014 Sale 50,144
VEITINGER KLAUS R DR Director Oct 10, 2014 Option Exercise 11,625
VEITINGER KLAUS R DR Director Oct 10, 2014 Sale 48,343
Berman Lance Chief Medical Officer and SVP Sep 24, 2014 Option Exercise 22,033
Berman Lance Chief Medical Officer and SVP Sep 24, 2014 Sale 110,000
ORBIMED ADVISORS LLC 10% Owner Sep 17, 2014 Sale 1,228,430
ORBIMED ADVISORS LLC 10% Owner Sep 16, 2014 Sale 1,146,836
5AM Partners II, LLC 10% Owner Sep 16, 2014 Sale 15,944,417
VEITINGER KLAUS R DR Director Sep 10, 2014 Option Exercise 19,377
VEITINGER KLAUS R DR Director Sep 10, 2014 Sale 95,851
Stahl Wilhelm SVP, Pharmaceutical Operations Aug 29, 2014 Option Exercise 66,520
Stahl Wilhelm SVP, Pharmaceutical Operations Aug 29, 2014 Sale 399,253
5AM Partners II, LLC 10% Owner Aug 26, 2014 Sale 2,555,104
5AM Partners II, LLC 10% Owner Aug 25, 2014 Sale 8,922,285
Berman Lance Chief Medical Officer and SVP Aug 22, 2014 Option Exercise 65,568
Berman Lance Chief Medical Officer and SVP Aug 25, 2014 Option Exercise 37,000
Berman Lance Chief Medical Officer and SVP Aug 22, 2014 Sale 385,343
Berman Lance Chief Medical Officer and SVP Aug 25, 2014 Sale 132,379
ORBIMED ADVISORS LLC 10% Owner Aug 15, 2014 Sale 26,086,500
VEITINGER KLAUS R DR Director Aug 11, 2014 Option Exercise 19,377
VEITINGER KLAUS R DR Director Aug 11, 2014 Sale 115,563
Stahl Wilhelm SVP, Pharmaceutical Operations Aug 08, 2014 Option Exercise 195,228
Stahl Wilhelm SVP, Pharmaceutical Operations Aug 08, 2014 Sale 1,237,085
Lockey Claire See Remarks Aug 08, 2014 Option Exercise 46,500
Lockey Claire See Remarks Aug 08, 2014 Sale 265,000
Berman Lance Chief Medical Officer and SVP Jul 24, 2014 Option Exercise 59,400
Berman Lance Chief Medical Officer and SVP Jul 22, 2014 Option Exercise 59,400
Berman Lance Chief Medical Officer and SVP Jul 23, 2014 Option Exercise 59,400
Berman Lance Chief Medical Officer and SVP Jul 23, 2014 Sale 363,622
Berman Lance Chief Medical Officer and SVP Jul 24, 2014 Sale 357,896
Berman Lance Chief Medical Officer and SVP Jul 22, 2014 Sale 354,993
VEITINGER KLAUS R DR Director Jul 10, 2014 Option Exercise 19,377
VEITINGER KLAUS R DR Director Jul 10, 2014 Sale 96,354
New Leaf Ventures I, L.P. Director Nov 20, 2013 Option Exercise 238,601
New Leaf Ventures I, L.P. Director Nov 20, 2013 Option Exercise 238,594
New Leaf Ventures I, L.P. Director Nov 20, 2013 Buy 2,045,758
HUNT RONALD Director Nov 20, 2013 Option Exercise 238,601
HUNT RONALD Director Nov 20, 2013 Option Exercise 238,594
HUNT RONALD Director Nov 20, 2013 Buy 2,045,758
SILVERSTEIN JONATHAN Director Nov 20, 2013 Option Exercise 300,102
SILVERSTEIN JONATHAN Director Nov 20, 2013 Option Exercise 296,601
SILVERSTEIN JONATHAN Director Nov 20, 2013 Buy 7,834,112
ORBIMED ADVISORS LLC 10% Owner Nov 20, 2013 Option Exercise 300,102
ORBIMED ADVISORS LLC 10% Owner Nov 20, 2013 Option Exercise 296,601
ORBIMED ADVISORS LLC 10% Owner Nov 20, 2013 Buy 7,834,112
ROCKLAGE SCOTT M Director Nov 20, 2013 Option Exercise 2,431
ROCKLAGE SCOTT M Director Nov 20, 2013 Option Exercise 2,384
ROCKLAGE SCOTT M Director Nov 20, 2013 Buy 103,004
ROCKLAGE SCOTT M Director Nov 20, 2013 Option Exercise 463,760
ROCKLAGE SCOTT M Director Nov 20, 2013 Option Exercise 462,439
ROCKLAGE SCOTT M Director Nov 20, 2013 Buy 3,996,608
5AM Partners III, LLC 10% Owner Nov 20, 2013 Option Exercise 96,041
5AM Partners III, LLC 10% Owner Nov 20, 2013 Option Exercise 94,897
5AM Partners III, LLC 10% Owner Nov 20, 2013 Buy 4,099,612
Orwin John A President & CEO Nov 20, 2013 Buy 165,000
5AM Partners II, LLC 10% Owner Nov 20, 2013 Option Exercise 370,150
5AM Partners II, LLC 10% Owner Nov 20, 2013 Option Exercise 369,926