Insider Transactions for Loxo Oncology, Inc. (LOXO)

Owner Relationship Date Transaction Cost # Shares Value($) Total Shares Form 4
Van Naarden Jacob Chief Operating Officer Feb 15, 2019 Option Exercise $235.00 19,000 4,465,000 0 Feb 15, 2019, 09:18 AM
Nanda Nisha Chief Development Officer Feb 15, 2019 Option Exercise $235.00 18,896 4,440,560 0 Feb 15, 2019, 09:17 AM
Naider Avi Z. Director Feb 15, 2019 Option Exercise $235.00 111,843 26,283,105 0 Feb 15, 2019, 09:16 AM
Flaherty Keith T. Director Feb 15, 2019 Option Exercise $235.00 9,732 2,287,020 0 Feb 15, 2019, 09:11 AM
ELMS STEVE Director Feb 15, 2019 Option Exercise $235.00 2,038,920 479,146,200 2,038,920 Feb 15, 2019, 09:09 AM
Bilenker Joshua H. President & CEO Feb 15, 2019 Option Exercise $235.00 30,000 7,050,000 0 Feb 15, 2019, 09:06 AM
Bilenker Joshua H. President & CEO Feb 15, 2019 Option Exercise $235.00 162,707 38,236,145 0 Feb 15, 2019, 09:06 AM
Van Naarden Jacob Chief Operating Officer Jul 09, 2018 Option Exercise $3.65 1,541 5,622 13,541 Jan 17, 2019, 08:08 AM
Bilenker Joshua H. President & CEO Jul 09, 2018 Option Exercise $1.18 7,500 8,880 141,207 Jan 17, 2019, 08:06 AM
Naider Avi Z. Director Dec 13, 2018 Buy $138.92 725 100,716 126,843 Dec 17, 2018, 05:07 PM
Van Naarden Jacob Chief Business Officer Dec 11, 2018 Option Exercise $7.57 11,500 87,051 20,700 Dec 12, 2018, 05:17 PM
Van Naarden Jacob Chief Business Officer Dec 10, 2018 Option Exercise $13.67 4,500 61,515 18,200 Dec 12, 2018, 05:17 PM
Van Naarden Jacob Chief Business Officer Dec 10, 2018 Sale $133.65 4,500 601,434 17,800 Dec 12, 2018, 05:17 PM
Van Naarden Jacob Chief Business Officer Dec 11, 2018 Sale $137.35 4,500 618,080 17,800 Dec 12, 2018, 05:17 PM
Burstein Jennifer Senior VP of Finance Dec 11, 2018 Option Exercise $11.35 1,250 14,188 1,250 Dec 12, 2018, 05:14 PM
Burstein Jennifer Senior VP of Finance Dec 10, 2018 Option Exercise $11.35 1,250 14,188 1,250 Dec 12, 2018, 05:14 PM
Burstein Jennifer Senior VP of Finance Dec 10, 2018 Sale $133.67 1,250 167,084 1,150 Dec 12, 2018, 05:14 PM
Burstein Jennifer Senior VP of Finance Dec 11, 2018 Sale $137.43 1,250 171,792 1,050 Dec 12, 2018, 05:14 PM
Bilenker Joshua H. President & CEO Dec 11, 2018 Option Exercise $13.67 10,000 136,700 174,407 Dec 12, 2018, 05:12 PM
Bilenker Joshua H. President & CEO Dec 10, 2018 Option Exercise $13.67 10,000 136,700 174,407 Dec 12, 2018, 05:12 PM
Bilenker Joshua H. President & CEO Dec 10, 2018 Sale $133.52 10,000 1,335,198 173,438 Dec 12, 2018, 05:12 PM
Bilenker Joshua H. President & CEO Dec 11, 2018 Sale $137.42 10,000 1,374,237 173,760 Dec 12, 2018, 05:12 PM
Van Naarden Jacob Chief Business Officer Nov 27, 2018 Option Exercise $8.23 4,500 37,031 18,200 Nov 28, 2018, 05:13 PM
Van Naarden Jacob Chief Business Officer Nov 26, 2018 Option Exercise $3.65 5,500 20,064 19,200 Nov 28, 2018, 05:13 PM
Van Naarden Jacob Chief Business Officer Nov 26, 2018 Sale $153.13 5,500 842,224 17,644 Nov 28, 2018, 05:13 PM
Van Naarden Jacob Chief Business Officer Nov 27, 2018 Sale $141.66 4,500 637,481 17,251 Nov 28, 2018, 05:13 PM
Burstein Jennifer Senior VP of Finance Nov 27, 2018 Option Exercise $11.35 1,250 14,188 1,250 Nov 28, 2018, 05:09 PM
Burstein Jennifer Senior VP of Finance Nov 26, 2018 Option Exercise $11.35 1,250 14,188 1,250 Nov 28, 2018, 05:09 PM
Burstein Jennifer Senior VP of Finance Nov 26, 2018 Sale $153.08 1,250 191,356 750 Nov 28, 2018, 05:09 PM
Burstein Jennifer Senior VP of Finance Nov 27, 2018 Sale $142.28 1,250 177,850 1,050 Nov 28, 2018, 05:09 PM
Bilenker Joshua H. President & CEO Nov 27, 2018 Option Exercise $13.67 10,000 136,700 174,407 Nov 28, 2018, 05:08 PM
Bilenker Joshua H. President & CEO Nov 26, 2018 Option Exercise $2.20 39,000 85,709 174,407 Nov 28, 2018, 05:08 PM
Bilenker Joshua H. President & CEO Nov 26, 2018 Sale $153.18 10,000 1,531,829 173,607 Nov 28, 2018, 05:08 PM
Bilenker Joshua H. President & CEO Nov 27, 2018 Sale $141.34 10,000 1,413,418 172,078 Nov 28, 2018, 05:08 PM
Van Naarden Jacob Chief Business Officer Oct 04, 2018 Option Exercise $3.65 4,500 16,416 18,200 Oct 05, 2018, 04:46 PM
Van Naarden Jacob Chief Business Officer Oct 03, 2018 Option Exercise $3.65 5,500 20,064 19,200 Oct 05, 2018, 04:46 PM
Van Naarden Jacob Chief Business Officer Oct 03, 2018 Sale $167.16 5,500 919,376 17,200 Oct 05, 2018, 04:46 PM
Van Naarden Jacob Chief Business Officer Oct 04, 2018 Sale $162.64 4,500 731,884 17,600 Oct 05, 2018, 04:46 PM
Burstein Jennifer Senior VP of Finance Oct 04, 2018 Option Exercise $11.35 1,250 14,188 1,250 Oct 05, 2018, 04:44 PM
Burstein Jennifer Senior VP of Finance Oct 03, 2018 Option Exercise $11.35 1,250 14,188 1,250 Oct 05, 2018, 04:44 PM
Burstein Jennifer Senior VP of Finance Oct 03, 2018 Sale $167.20 1,250 208,996 660 Oct 05, 2018, 04:44 PM
Burstein Jennifer Senior VP of Finance Oct 04, 2018 Sale $162.64 1,250 203,304 711 Oct 05, 2018, 04:44 PM
Bilenker Joshua H. President & CEO Oct 04, 2018 Option Exercise $3.65 10,000 36,480 145,407 Oct 05, 2018, 04:42 PM
Bilenker Joshua H. President & CEO Oct 03, 2001 Option Exercise $3.65 10,000 36,480 145,407 Oct 05, 2018, 04:42 PM
Bilenker Joshua H. President & CEO Oct 03, 2018 Sale $168.18 7,095 1,193,254 141,277 Oct 05, 2018, 04:42 PM
Bilenker Joshua H. President & CEO Oct 03, 2001 Sale $165.01 2,905 479,342 142,502 Oct 05, 2018, 04:42 PM
Bilenker Joshua H. President & CEO Oct 04, 2018 Sale $162.62 10,000 1,626,247 143,707 Oct 05, 2018, 04:42 PM
Kunkel Lori Anne Director Oct 01, 2018 Option Exercise $3.65 5,000 18,240 5,000 Oct 03, 2018, 05:05 PM
Kunkel Lori Anne Director Oct 01, 2018 Sale $170.37 5,000 851,830 500 Oct 03, 2018, 05:05 PM
Burstein Jennifer Senior VP of Finance Sep 12, 2018 Option Exercise $11.35 1,250 14,188 1,250 Sep 14, 2018, 06:19 PM
Burstein Jennifer Senior VP of Finance Sep 13, 2018 Option Exercise $11.35 1,250 14,188 1,250 Sep 14, 2018, 06:19 PM
Burstein Jennifer Senior VP of Finance Sep 12, 2018 Sale $167.89 1,250 209,868 700 Sep 14, 2018, 06:19 PM
Burstein Jennifer Senior VP of Finance Sep 13, 2018 Sale $166.02 1,250 207,523 500 Sep 14, 2018, 06:19 PM
Bilenker Joshua H. President & CEO Sep 12, 2018 Option Exercise $1.18 10,000 11,840 145,407 Sep 14, 2018, 06:17 PM
Bilenker Joshua H. President & CEO Sep 13, 2018 Option Exercise $1.81 10,000 18,067 145,407 Sep 14, 2018, 06:17 PM
Bilenker Joshua H. President & CEO Sep 12, 2018 Sale $166.42 10,000 1,664,159 144,707 Sep 14, 2018, 06:17 PM
Bilenker Joshua H. President & CEO Sep 13, 2018 Sale $165.98 10,000 1,659,806 139,771 Sep 14, 2018, 06:17 PM
Van Naarden Jacob Chief Business Officer Sep 12, 2018 Option Exercise $3.65 5,500 20,064 19,200 Sep 14, 2018, 06:14 PM
Van Naarden Jacob Chief Business Officer Sep 13, 2018 Option Exercise $3.65 4,500 16,416 18,200 Sep 14, 2018, 06:14 PM
Van Naarden Jacob Chief Business Officer Sep 12, 2018 Sale $166.60 5,500 916,277 18,444 Sep 14, 2018, 06:14 PM
Van Naarden Jacob Chief Business Officer Sep 13, 2018 Sale $165.98 4,500 746,903 15,500 Sep 14, 2018, 06:14 PM
Van Naarden Jacob Chief Business Officer Aug 13, 2018 Option Exercise $3.65 5,500 20,064 19,200 Aug 15, 2018, 05:27 PM
Van Naarden Jacob Chief Business Officer Aug 14, 2018 Option Exercise $3.65 4,500 16,416 18,200 Aug 15, 2018, 05:27 PM
Van Naarden Jacob Chief Business Officer Aug 13, 2018 Sale $158.87 5,500 873,804 18,470 Aug 15, 2018, 05:27 PM
Van Naarden Jacob Chief Business Officer Aug 14, 2018 Sale $159.92 4,500 719,642 17,600 Aug 15, 2018, 05:27 PM
Burstein Jennifer Senior VP of Finance Aug 13, 2018 Option Exercise $11.35 1,250 14,188 1,250 Aug 15, 2018, 05:25 PM
Burstein Jennifer Senior VP of Finance Aug 14, 2018 Option Exercise $11.35 1,250 14,188 1,250 Aug 15, 2018, 05:25 PM
Burstein Jennifer Senior VP of Finance Aug 13, 2018 Sale $158.26 1,250 197,827 450 Aug 15, 2018, 05:25 PM
Burstein Jennifer Senior VP of Finance Aug 14, 2018 Sale $160.22 1,250 200,279 800 Aug 15, 2018, 05:25 PM
Bilenker Joshua H. President & CEO Aug 13, 2018 Option Exercise $1.18 10,000 11,840 145,407 Aug 15, 2018, 05:23 PM
Bilenker Joshua H. President & CEO Aug 14, 2018 Option Exercise $1.18 10,000 11,840 145,407 Aug 15, 2018, 05:23 PM
Bilenker Joshua H. President & CEO Aug 13, 2018 Sale $158.91 10,000 1,589,095 143,807 Aug 15, 2018, 05:23 PM
Bilenker Joshua H. President & CEO Aug 14, 2018 Sale $159.91 10,000 1,599,088 143,807 Aug 15, 2018, 05:23 PM
AISLING CAPITAL III LP 10% Owner Jul 10, 2018 Sale $179.43 1,400,000 251,201,990 2,038,920 Jul 12, 2018, 04:45 PM
Burstein Jennifer Senior VP of Finance Jul 09, 2018 Option Exercise $11.35 1,500 17,025 1,500 Jul 11, 2018, 05:04 PM
Burstein Jennifer Senior VP of Finance Jul 09, 2018 Sale $187.25 1,500 280,870 1,300 Jul 11, 2018, 05:04 PM
Van Naarden Jacob Chief Business Officer Jul 09, 2018 Option Exercise $3.65 1,541 5,622 15,241 Jul 11, 2018, 05:03 PM
Van Naarden Jacob Chief Business Officer Jul 10, 2018 Option Exercise $3.65 1,541 5,622 15,241 Jul 11, 2018, 05:03 PM
Van Naarden Jacob Chief Business Officer Jul 10, 2018 Sale $179.69 1,541 276,907 14,561 Jul 11, 2018, 05:03 PM
Van Naarden Jacob Chief Business Officer Jul 09, 2018 Sale $187.30 1,541 288,631 14,941 Jul 11, 2018, 05:03 PM
Bilenker Joshua H. President & CEO Jul 09, 2018 Option Exercise $1.18 7,500 8,880 142,907 Jul 11, 2018, 05:01 PM
Bilenker Joshua H. President & CEO Jul 10, 2018 Option Exercise $1.18 7,500 8,880 142,907 Jul 11, 2018, 05:01 PM
Bilenker Joshua H. President & CEO Jul 10, 2018 Sale $179.72 7,500 1,347,923 140,707 Jul 11, 2018, 05:01 PM
Bilenker Joshua H. President & CEO Jul 09, 2018 Sale $187.23 7,500 1,404,241 142,007 Jul 11, 2018, 05:01 PM
Burstein Jennifer Senior VP of Finance Jun 19, 2018 Option Exercise $11.35 1,700 19,295 1,700 Jun 21, 2018, 05:04 PM
Burstein Jennifer Senior VP of Finance Jun 19, 2018 Sale $176.99 1,700 300,888 900 Jun 21, 2018, 05:04 PM
Van Naarden Jacob Chief Business Officer Jun 20, 2018 Option Exercise $3.65 13,541 49,398 13,541 Jun 21, 2018, 05:03 PM
Van Naarden Jacob Chief Business Officer Jun 19, 2018 Option Exercise $3.65 1,541 5,622 1,541 Jun 21, 2018, 05:03 PM
Van Naarden Jacob Chief Business Officer Jun 19, 2018 Sale $176.94 1,541 272,665 676 Jun 21, 2018, 05:03 PM
Van Naarden Jacob Chief Business Officer Jun 20, 2018 Sale $179.34 1,541 276,370 12,400 Jun 21, 2018, 05:03 PM
Bilenker Joshua H. President & CEO Jun 19, 2018 Option Exercise $1.18 7,500 8,880 135,207 Jun 21, 2018, 05:02 PM
Bilenker Joshua H. President & CEO Jun 20, 2018 Option Exercise $1.18 35,500 42,032 163,207 Jun 21, 2018, 05:02 PM
Bilenker Joshua H. President & CEO Jun 20, 2018 Sale $179.25 7,500 1,344,406 160,507 Jun 21, 2018, 05:02 PM
Bilenker Joshua H. President & CEO Jun 19, 2018 Sale $178.25 21,000 3,743,353 41,768 Jun 21, 2018, 05:02 PM
Bilenker Joshua H. President & CEO Jun 19, 2018 Sale $177.04 7,500 1,327,768 132,871 Jun 21, 2018, 05:02 PM
Bilenker Joshua H. President & CEO Jun 20, 2018 Sale $179.33 21,000 3,765,835 17,664 Jun 21, 2018, 05:02 PM
Kunkel Lori Anne Director Jun 14, 2018 Option Exercise $6.54 32,392 211,708 39,232 Jun 18, 2018, 05:00 PM
Kunkel Lori Anne Director Jun 15, 2018 Sale $176.86 6,840 1,209,691 5,605 Jun 18, 2018, 05:00 PM
Kunkel Lori Anne Director Jun 14, 2018 Sale $180.46 32,392 5,845,561 10,792 Jun 18, 2018, 05:00 PM
MAYLEBEN TIMOTHY M Director Jun 08, 2018 Option Exercise $21.75 10,000 217,550 10,000 Jun 11, 2018, 06:02 PM
MAYLEBEN TIMOTHY M Director Jun 08, 2018 Sale $179.55 10,000 1,795,470 0 Jun 11, 2018, 06:02 PM
Fuhrman Alan Director Jun 08, 2018 Option Exercise $11.35 2,625 29,794 2,625 Jun 11, 2018, 06:01 PM
Fuhrman Alan Director Jun 08, 2018 Sale $178.07 2,625 467,436 0 Jun 11, 2018, 06:01 PM
Flaherty Keith T. Director Jun 07, 2018 Option Exercise $1.18 50,000 59,200 59,732 Jun 11, 2018, 06:00 PM
Flaherty Keith T. Director Jun 07, 2018 Sale $173.54 50,000 8,677,032 57,832 Jun 11, 2018, 06:00 PM
Van Naarden Jacob Chief Business Officer May 15, 2018 Option Exercise $3.65 1,541 5,622 1,541 May 16, 2018, 04:46 PM
Van Naarden Jacob Chief Business Officer May 14, 2018 Option Exercise $3.65 1,541 5,622 1,541 May 16, 2018, 04:46 PM
Van Naarden Jacob Chief Business Officer May 15, 2018 Sale $137.29 1,541 211,566 1,341 May 16, 2018, 04:46 PM
Van Naarden Jacob Chief Business Officer May 14, 2018 Sale $137.54 1,541 211,949 1,300 May 16, 2018, 04:46 PM
Burstein Jennifer Senior VP of Finance May 14, 2018 Option Exercise $11.35 1,700 19,295 1,700 May 16, 2018, 04:45 PM
Burstein Jennifer Senior VP of Finance May 14, 2018 Sale $136.93 1,700 232,784 1,500 May 16, 2018, 04:45 PM
Bilenker Joshua H. President & CEO May 15, 2018 Option Exercise $1.18 7,500 8,880 190,207 May 16, 2018, 04:44 PM
Bilenker Joshua H. President & CEO May 14, 2018 Option Exercise $1.18 7,500 8,880 190,207 May 16, 2018, 04:44 PM
Bilenker Joshua H. President & CEO May 15, 2018 Sale $137.41 7,500 1,030,575 189,507 May 16, 2018, 04:44 PM
Bilenker Joshua H. President & CEO May 14, 2018 Sale $135.61 7,500 1,017,071 190,107 May 16, 2018, 04:44 PM
Burstein Jennifer Senior VP of Finance Apr 24, 2018 Option Exercise $11.35 1,700 19,295 1,700 Apr 26, 2018, 04:33 PM
Burstein Jennifer Senior VP of Finance Apr 24, 2018 Sale $131.65 1,700 223,804 1,400 Apr 26, 2018, 04:33 PM
Van Naarden Jacob Chief Business Officer Apr 24, 2018 Option Exercise $3.65 1,541 5,622 1,541 Apr 26, 2018, 04:32 PM
Van Naarden Jacob Chief Business Officer Apr 25, 2018 Option Exercise $3.65 1,541 5,622 1,541 Apr 26, 2018, 04:32 PM
Van Naarden Jacob Chief Business Officer Apr 24, 2018 Sale $131.67 1,541 202,898 1,300 Apr 26, 2018, 04:32 PM
Van Naarden Jacob Chief Business Officer Apr 25, 2018 Sale $130.80 1,541 201,563 1,241 Apr 26, 2018, 04:32 PM
Bilenker Joshua H. President & CEO Apr 24, 2018 Option Exercise $1.18 7,500 8,880 190,207 Apr 26, 2018, 04:31 PM
Bilenker Joshua H. President & CEO Apr 25, 2018 Option Exercise $1.18 7,500 8,880 190,207 Apr 26, 2018, 04:31 PM
Bilenker Joshua H. President & CEO Apr 24, 2018 Sale $131.39 7,500 985,432 188,490 Apr 26, 2018, 04:31 PM
Bilenker Joshua H. President & CEO Apr 25, 2018 Sale $130.86 7,500 981,424 189,407 Apr 26, 2018, 04:31 PM
Kunkel Lori Anne Director Apr 20, 2018 Sale $132.68 5,000 663,379 10,940 Apr 24, 2018, 04:30 PM
Burstein Jennifer Senior VP of Finance Mar 13, 2018 Option Exercise $11.35 1,700 19,295 1,700 Mar 15, 2018, 05:02 PM
Burstein Jennifer Senior VP of Finance Mar 13, 2018 Sale $131.33 1,700 223,262 1,600 Mar 15, 2018, 05:02 PM
Van Naarden Jacob Chief Business Officer Mar 13, 2018 Option Exercise $3.65 1,541 5,622 1,541 Mar 15, 2018, 05:01 PM
Van Naarden Jacob Chief Business Officer Mar 14, 2018 Option Exercise $3.65 1,541 5,622 1,541 Mar 15, 2018, 05:01 PM
Van Naarden Jacob Chief Business Officer Mar 14, 2018 Sale $131.46 1,541 202,580 646 Mar 15, 2018, 05:01 PM
Van Naarden Jacob Chief Business Officer Mar 13, 2018 Sale $131.35 1,541 202,415 1,441 Mar 15, 2018, 05:01 PM
Bilenker Joshua H. President & CEO Mar 13, 2018 Option Exercise $1.18 7,500 8,880 190,207 Mar 15, 2018, 05:00 PM
Bilenker Joshua H. President & CEO Mar 14, 2018 Option Exercise $1.18 7,500 8,880 190,207 Mar 15, 2018, 05:00 PM
Bilenker Joshua H. President & CEO Mar 14, 2018 Sale $131.50 7,500 986,213 188,407 Mar 15, 2018, 05:00 PM
Bilenker Joshua H. President & CEO Mar 13, 2018 Sale $131.58 7,500 986,843 189,907 Mar 15, 2018, 05:00 PM
Burstein Jennifer Senior VP of Finance Feb 12, 2018 Option Exercise $11.35 1,700 19,295 1,700 Feb 14, 2018, 05:37 PM
Burstein Jennifer Senior VP of Finance Feb 12, 2018 Sale $93.24 1,700 158,504 1,400 Feb 14, 2018, 05:37 PM
Bilenker Joshua H. President & CEO Feb 12, 2018 Option Exercise $1.18 7,500 8,880 190,207 Feb 14, 2018, 05:36 PM
Bilenker Joshua H. President & CEO Feb 13, 2018 Option Exercise $1.18 7,500 8,880 190,207 Feb 14, 2018, 05:36 PM
Bilenker Joshua H. President & CEO Feb 13, 2018 Sale $99.75 7,500 748,152 189,107 Feb 14, 2018, 05:36 PM
Bilenker Joshua H. President & CEO Feb 12, 2018 Sale $93.38 7,500 700,377 188,957 Feb 14, 2018, 05:36 PM
Van Naarden Jacob Chief Business Officer Feb 12, 2018 Option Exercise $3.65 1,541 5,622 1,541 Feb 14, 2018, 05:35 PM
Van Naarden Jacob Chief Business Officer Feb 13, 2018 Option Exercise $3.65 1,541 5,622 1,541 Feb 14, 2018, 05:35 PM
Van Naarden Jacob Chief Business Officer Feb 13, 2018 Sale $99.24 1,541 152,935 1,241 Feb 14, 2018, 05:35 PM
Van Naarden Jacob Chief Business Officer Feb 12, 2018 Sale $93.43 1,541 143,978 1,041 Feb 14, 2018, 05:35 PM
Naider Avi Z. Director Jan 22, 2018 Sale $100.00 15,000 1,500,000 126,118 Jan 25, 2018, 05:09 PM
Burstein Jennifer Senior VP of Finance Jan 16, 2018 Option Exercise $11.35 1,500 17,025 1,500 Jan 18, 2018, 05:02 PM
Burstein Jennifer Senior VP of Finance Jan 16, 2018 Sale $87.50 1,500 131,243 0 Jan 18, 2018, 05:02 PM
Van Naarden Jacob Chief Business Officer Jan 17, 2018 Option Exercise $3.65 1,541 5,622 1,541 Jan 18, 2018, 05:02 PM
Van Naarden Jacob Chief Business Officer Jan 16, 2018 Option Exercise $3.65 1,541 5,622 1,541 Jan 18, 2018, 05:02 PM
Van Naarden Jacob Chief Business Officer Jan 17, 2018 Sale $88.30 1,541 136,065 1,095 Jan 18, 2018, 05:02 PM
Van Naarden Jacob Chief Business Officer Jan 16, 2018 Sale $88.13 1,541 135,802 900 Jan 18, 2018, 05:02 PM
Bilenker Joshua H. President & CEO Jan 17, 2018 Option Exercise $1.18 7,500 8,880 190,207 Jan 18, 2018, 05:01 PM
Bilenker Joshua H. President & CEO Jan 16, 2018 Option Exercise $1.18 7,500 8,880 190,207 Jan 18, 2018, 05:01 PM
Bilenker Joshua H. President & CEO Jan 17, 2018 Sale $88.48 7,500 663,584 189,103 Jan 18, 2018, 05:01 PM
Bilenker Joshua H. President & CEO Jan 16, 2018 Sale $87.94 7,500 659,515 187,288 Jan 18, 2018, 05:01 PM
MAYLEBEN TIMOTHY M Director Dec 20, 2017 Sale $80.49 10,000 804,948 0 Dec 22, 2017, 04:14 PM
AISLING CAPITAL III LP 10% Owner Dec 19, 2017 Sale $80.50 250,000 20,125,000 3,438,920 Dec 20, 2017, 04:31 PM
Burstein Jennifer Vice President of Finance Dec 14, 2017 Option Exercise $11.35 1,700 19,295 1,700 Dec 18, 2017, 05:44 PM
Burstein Jennifer Vice President of Finance Dec 14, 2017 Sale $83.27 1,700 141,554 800 Dec 18, 2017, 05:44 PM
Van Naarden Jacob Chief Business Officer Dec 14, 2017 Option Exercise $3.65 1,541 5,622 1,541 Dec 18, 2017, 05:42 PM
Van Naarden Jacob Chief Business Officer Dec 15, 2017 Option Exercise $3.65 1,541 5,622 1,541 Dec 18, 2017, 05:42 PM
Van Naarden Jacob Chief Business Officer Dec 14, 2017 Sale $83.27 1,541 128,319 700 Dec 18, 2017, 05:42 PM
Van Naarden Jacob Chief Business Officer Dec 15, 2017 Sale $79.12 1,541 121,921 1,141 Dec 18, 2017, 05:42 PM
Bilenker Joshua H. President & CEO Dec 14, 2017 Option Exercise $1.18 7,500 8,880 190,207 Dec 18, 2017, 05:40 PM
Bilenker Joshua H. President & CEO Dec 15, 2017 Option Exercise $1.18 7,500 8,880 190,207 Dec 18, 2017, 05:40 PM
Bilenker Joshua H. President & CEO Dec 14, 2017 Sale $83.35 7,500 625,120 187,607 Dec 18, 2017, 05:40 PM
Bilenker Joshua H. President & CEO Dec 15, 2017 Sale $78.90 7,500 591,739 189,507 Dec 18, 2017, 05:40 PM
Bonita David P Director Dec 08, 2017 Sale $82.50 250,000 20,625,000 941,000 Dec 12, 2017, 02:06 PM
ORBIMED ADVISORS LLC Director Dec 08, 2017 Sale $82.50 250,000 20,625,000 941,000 Dec 12, 2017, 02:02 PM
Burstein Jennifer Vice President of Finance Nov 27, 2017 Option Exercise $11.35 1,700 19,295 1,700 Nov 29, 2017, 05:25 PM
Burstein Jennifer Vice President of Finance Nov 27, 2017 Sale $74.82 1,700 127,193 600 Nov 29, 2017, 05:25 PM
Van Naarden Jacob Chief Business Officer Nov 27, 2017 Option Exercise $3.65 1,541 5,622 1,541 Nov 29, 2017, 05:21 PM
Van Naarden Jacob Chief Business Officer Nov 28, 2017 Option Exercise $3.65 1,541 5,622 1,541 Nov 29, 2017, 05:21 PM
Van Naarden Jacob Chief Business Officer Nov 27, 2017 Sale $74.83 1,541 115,316 700 Nov 29, 2017, 05:21 PM
Van Naarden Jacob Chief Business Officer Nov 28, 2017 Sale $74.16 1,541 114,282 941 Nov 29, 2017, 05:21 PM
Bilenker Joshua H. President & CEO Nov 27, 2017 Option Exercise $1.18 7,500 8,880 190,207 Nov 29, 2017, 05:17 PM
Bilenker Joshua H. President & CEO Nov 28, 2017 Option Exercise $1.18 7,500 8,880 190,207 Nov 29, 2017, 05:17 PM
Bilenker Joshua H. President & CEO Nov 27, 2017 Sale $74.68 7,500 560,100 185,514 Nov 29, 2017, 05:17 PM
Bilenker Joshua H. President & CEO Nov 28, 2017 Sale $74.22 7,500 556,648 187,807 Nov 29, 2017, 05:17 PM
AISLING CAPITAL III LP 10% Owner Nov 22, 2017 Sale $75.00 500,000 37,500,000 3,688,920 Nov 27, 2017, 07:29 PM
MAYLEBEN TIMOTHY M Director Nov 22, 2017 Option Exercise $20.91 3,000 62,730 13,000 Nov 27, 2017, 04:56 PM
MAYLEBEN TIMOTHY M Director Nov 22, 2017 Sale $75.85 3,000 227,563 10,000 Nov 27, 2017, 04:56 PM
Bonita David P Director Nov 22, 2017 Sale $75.00 267,000 20,025,000 1,191,000 Nov 27, 2017, 03:36 PM
ORBIMED ADVISORS LLC Director Nov 22, 2017 Sale $75.00 267,000 20,025,000 1,191,000 Nov 27, 2017, 03:30 PM
Flaherty Keith T. Director Nov 20, 2017 Sale $75.99 7,250 550,921 12,493 Nov 22, 2017, 05:05 PM
Bonita David P Director Nov 16, 2017 Sale $74.26 270,000 20,051,389 1,681,320 Nov 20, 2017, 07:36 PM
ORBIMED ADVISORS LLC Director Nov 16, 2017 Sale $74.26 270,000 20,051,389 1,681,320 Nov 20, 2017, 07:31 PM
Kunkel Lori Anne Director Nov 02, 2017 Sale $84.91 5,000 424,570 15,040 Nov 06, 2017, 05:03 PM
Burstein Jennifer Vice President of Finance Oct 30, 2017 Option Exercise $11.35 1,700 19,295 1,700 Nov 01, 2017, 05:08 PM
Burstein Jennifer Vice President of Finance Oct 30, 2017 Sale $87.19 1,700 148,219 400 Nov 01, 2017, 05:08 PM
Van Naarden Jacob Chief Business Officer Oct 30, 2017 Option Exercise $3.65 1,541 5,622 1,541 Nov 01, 2017, 05:06 PM
Van Naarden Jacob Chief Business Officer Oct 31, 2017 Option Exercise $3.65 1,541 5,622 1,541 Nov 01, 2017, 05:06 PM
Van Naarden Jacob Chief Business Officer Oct 31, 2017 Sale $86.52 1,541 133,321 400 Nov 01, 2017, 05:06 PM
Van Naarden Jacob Chief Business Officer Oct 30, 2017 Sale $87.26 1,541 134,468 441 Nov 01, 2017, 05:06 PM
Bilenker Joshua H. President & CEO Oct 30, 2017 Option Exercise $1.18 7,500 8,880 196,207 Nov 01, 2017, 05:03 PM
Bilenker Joshua H. President & CEO Oct 31, 2017 Option Exercise $1.18 7,500 8,880 196,207 Nov 01, 2017, 05:03 PM
Bilenker Joshua H. President & CEO Oct 31, 2017 Sale $86.49 7,500 648,702 193,246 Nov 01, 2017, 05:03 PM
Bilenker Joshua H. President & CEO Oct 30, 2017 Sale $87.20 7,500 653,967 190,517 Nov 01, 2017, 05:03 PM
Naider Avi Z. Director Oct 16, 2017 Sale $90.00 5,000 450,000 144,118 Oct 18, 2017, 05:03 PM
Burstein Jennifer Vice President of Finance Sep 18, 2017 Option Exercise $11.35 1,700 19,295 1,700 Sep 20, 2017, 05:09 PM
Burstein Jennifer Vice President of Finance Sep 18, 2017 Sale $89.10 1,700 151,470 1,057 Sep 20, 2017, 05:09 PM
Naider Avi Z. Director Sep 18, 2017 Sale $90.00 5,000 450,000 149,118 Sep 20, 2017, 05:07 PM
Van Naarden Jacob Chief Business Officer Sep 18, 2017 Option Exercise $3.65 1,541 5,622 1,541 Sep 20, 2017, 05:05 PM
Van Naarden Jacob Chief Business Officer Sep 19, 2017 Option Exercise $3.65 1,541 5,622 1,541 Sep 20, 2017, 05:05 PM
Van Naarden Jacob Chief Business Officer Sep 18, 2017 Sale $89.20 1,541 137,462 1,185 Sep 20, 2017, 05:05 PM
Van Naarden Jacob Chief Business Officer Sep 19, 2017 Sale $88.79 1,541 136,827 1,044 Sep 20, 2017, 05:05 PM
Bilenker Joshua H. President & CEO Sep 18, 2017 Option Exercise $1.18 7,500 8,880 196,207 Sep 20, 2017, 05:04 PM
Bilenker Joshua H. President & CEO Sep 19, 2017 Option Exercise $1.18 7,500 8,880 196,207 Sep 20, 2017, 05:04 PM
Bilenker Joshua H. President & CEO Sep 18, 2017 Sale $89.25 7,500 669,406 195,103 Sep 20, 2017, 05:04 PM
Bilenker Joshua H. President & CEO Sep 19, 2017 Sale $88.78 7,500 665,870 193,843 Sep 20, 2017, 05:04 PM
Naider Avi Z. Director Sep 13, 2017 Sale $90.00 5,000 450,000 154,118 Sep 15, 2017, 05:06 PM
Kunkel Lori Anne Director Aug 22, 2017 Sale $75.17 10,000 751,731 16,840 Aug 23, 2017, 06:35 PM
Flaherty Keith T. Director Aug 21, 2017 Sale $72.26 7,250 523,883 20,432 Aug 23, 2017, 06:33 PM
Burstein Jennifer Vice President of Finance Aug 14, 2017 Option Exercise $11.35 1,700 19,295 1,700 Aug 16, 2017, 05:24 PM
Burstein Jennifer Vice President of Finance Aug 14, 2017 Sale $73.73 1,700 125,347 600 Aug 16, 2017, 05:24 PM
Van Naarden Jacob Chief Business Officer Aug 14, 2017 Option Exercise $3.65 1,541 5,622 1,541 Aug 16, 2017, 05:22 PM
Van Naarden Jacob Chief Business Officer Aug 15, 2017 Option Exercise $3.65 1,541 5,622 1,541 Aug 16, 2017, 05:22 PM
Van Naarden Jacob Chief Business Officer Aug 14, 2017 Sale $73.73 1,541 113,619 541 Aug 16, 2017, 05:22 PM
Van Naarden Jacob Chief Business Officer Aug 15, 2017 Sale $73.42 1,541 113,134 0 Aug 16, 2017, 05:22 PM
Bilenker Joshua H. President & CEO Aug 14, 2017 Option Exercise $1.18 7,500 8,880 196,207 Aug 16, 2017, 05:20 PM
Bilenker Joshua H. President & CEO Aug 15, 2017 Option Exercise $1.18 7,500 8,880 196,207 Aug 16, 2017, 05:20 PM
Bilenker Joshua H. President & CEO Aug 14, 2017 Sale $73.73 7,500 553,006 191,190 Aug 16, 2017, 05:20 PM
Bilenker Joshua H. President & CEO Aug 15, 2017 Sale $73.39 7,500 550,443 189,643 Aug 16, 2017, 05:20 PM
Flaherty Keith T. Director May 22, 2017 Sale $45.09 7,250 326,936 27,141 May 24, 2017, 04:02 PM
Flaherty Keith T. Director Feb 21, 2017 Sale $41.45 7,250 300,517 31,482 Feb 23, 2017, 04:34 PM
AISLING CAPITAL III LP 10% Owner Jan 10, 2017 Buy $31.00 160,000 4,960,000 4,188,920 Jan 12, 2017, 05:17 PM
Flaherty Keith T. Director Dec 19, 2016 Sale $30.23 7,250 219,167 38,732 Dec 21, 2016, 05:30 PM
Flaherty Keith T. Director Sep 07, 2016 Sale $30.00 14,500 435,000 45,982 Sep 09, 2016, 04:34 PM
Flaherty Keith T. Director Aug 11, 2016 Sale $26.00 15,000 389,967 60,482 Aug 12, 2016, 05:05 PM
ORBIMED ADVISORS LLC Director Aug 10, 2016 Sale $26.96 447,857 12,074,224 1,728,000 Aug 12, 2016, 04:36 PM
Bonita David P Director Aug 10, 2016 Sale $26.96 447,857 12,074,224 1,728,000 Aug 12, 2016, 04:32 PM
AISLING CAPITAL III LP 10% Owner May 17, 2016 Buy $21.50 232,558 4,999,997 4,028,920 May 19, 2016, 04:24 PM
AISLING CAPITAL III LP 10% Owner Dec 11, 2015 Buy $27.50 200 5,500 3,796,362 Dec 15, 2015, 06:28 PM
Naider Avi Z. Director Nov 17, 2015 Buy $26.50 3,773 99,985 159,118 Nov 19, 2015, 07:51 PM
AISLING CAPITAL III LP 10% Owner Nov 17, 2015 Buy $26.50 265,000 7,022,500 3,796,182 Nov 19, 2015, 05:34 PM
AISLING CAPITAL III LP 10% Owner Nov 13, 2015 Buy $27.47 1,955 53,704 3,531,182 Nov 16, 2015, 05:16 PM
AISLING CAPITAL III LP 10% Owner Nov 12, 2015 Buy $27.65 76,714 2,121,319 3,529,207 Nov 16, 2015, 05:16 PM
GOLDSTEIN DOV A MD CFO and Treasurer Apr 02, 2015 Option Exercise $6.40 4,005 25,629 65,873 Apr 03, 2015, 04:50 PM
GOLDSTEIN DOV A MD CFO and Treasurer Apr 01, 2015 Option Exercise $6.46 39,212 253,249 61,868 Apr 03, 2015, 04:50 PM
ORBIMED ADVISORS LLC 10% Owner Aug 06, 2014 Buy $13.00 275,385 3,580,005 2,175,857 Aug 06, 2014, 05:01 PM
Sonsini Peter W. 10% Owner Aug 06, 2014 Buy $13.00 230,769 2,999,997 1,789,420 Aug 06, 2014, 04:29 PM
Weller Harry R 10% Owner Aug 06, 2014 Buy $13.00 230,769 2,999,997 1,789,420 Aug 06, 2014, 04:28 PM
Viswanathan Ravi 10% Owner Aug 06, 2014 Buy $13.00 230,769 2,999,997 1,789,420 Aug 06, 2014, 04:28 PM
SANDELL SCOTT D 10% Owner Aug 06, 2014 Buy $13.00 230,769 2,999,997 1,789,420 Aug 06, 2014, 04:27 PM
MOTT DAVID M 10% Owner Aug 06, 2014 Buy $13.00 230,769 2,999,997 1,789,420 Aug 06, 2014, 04:27 PM
KOLLURI KRISHNA KITTU 10% Owner Aug 06, 2014 Buy $13.00 230,769 2,999,997 1,789,420 Aug 06, 2014, 04:27 PM
KERINS PATRICK J 10% Owner Aug 06, 2014 Buy $13.00 230,769 2,999,997 1,789,420 Aug 06, 2014, 04:26 PM
Florence Anthony A. Jr. 10% Owner Aug 06, 2014 Buy $13.00 230,769 2,999,997 1,789,420 Aug 06, 2014, 04:26 PM
DRANT RYAN D 10% Owner Aug 06, 2014 Buy $13.00 230,769 2,999,997 1,789,420 Aug 06, 2014, 04:26 PM
BASKETT FOREST 10% Owner Aug 06, 2014 Buy $13.00 230,769 2,999,997 1,789,420 Aug 06, 2014, 04:25 PM
BARRIS PETER J 10% Owner Aug 06, 2014 Buy $13.00 230,769 2,999,997 1,789,420 Aug 06, 2014, 04:25 PM
BARRETT M JAMES Director Aug 06, 2014 Buy $13.00 230,769 2,999,997 1,789,420 Aug 06, 2014, 04:25 PM
New Enterprise Associates 14, L.P. 10% Owner Aug 06, 2013 Buy $13.00 230,769 2,999,997 1,789,420 Aug 06, 2014, 04:24 PM
Bonita David P Director Aug 06, 2014 Buy $13.00 275,385 3,580,005 2,175,857 Aug 06, 2014, 04:17 PM
Naider Avi Z. Director Aug 06, 2014 Buy $13.00 3,846 49,998 155,345 Aug 06, 2014, 04:15 PM
GOLDSTEIN DOV A MD CFO and Treasurer Aug 06, 2014 Buy $13.00 413,077 5,370,001 3,452,493 Aug 06, 2014, 04:12 PM
ELMS STEVE Director Aug 06, 2014 Buy $13.00 413,077 5,370,001 3,452,493 Aug 06, 2014, 04:11 PM
AISLING CAPITAL III LP 10% Owner Aug 06, 2014 Buy $13.00 413,077 5,370,001 3,452,493 Aug 06, 2014, 04:11 PM
Flynn James E 10% Owner Aug 06, 2014 Buy $13.00 307,600 3,998,800 586,651 Aug 06, 2014, 01:04 PM
Flynn James E 10% Owner Aug 06, 2014 Buy $13.01 296,125 3,853,488 296,125 Aug 06, 2014, 01:04 PM
Flynn James E 10% Owner Aug 06, 2014 Buy $13.01 239,300 3,114,020 239,300 Aug 06, 2014, 01:04 PM
Flynn James E 10% Owner Aug 06, 2014 Buy $13.00 246,631 3,206,203 469,470 Aug 06, 2014, 01:04 PM

Desktop Version

Owner Relationship Date Transaction Value($)
Van Naarden Jacob Chief Operating Officer Feb 15, 2019 Option Exercise 4,465,000
Nanda Nisha Chief Development Officer Feb 15, 2019 Option Exercise 4,440,560
Naider Avi Z. Director Feb 15, 2019 Option Exercise 26,283,105
Flaherty Keith T. Director Feb 15, 2019 Option Exercise 2,287,020
ELMS STEVE Director Feb 15, 2019 Option Exercise 479,146,200
Bilenker Joshua H. President & CEO Feb 15, 2019 Option Exercise 7,050,000
Bilenker Joshua H. President & CEO Feb 15, 2019 Option Exercise 38,236,145
Van Naarden Jacob Chief Operating Officer Jul 09, 2018 Option Exercise 5,622
Bilenker Joshua H. President & CEO Jul 09, 2018 Option Exercise 8,880
Naider Avi Z. Director Dec 13, 2018 Buy 100,716
Van Naarden Jacob Chief Business Officer Dec 11, 2018 Option Exercise 87,051
Van Naarden Jacob Chief Business Officer Dec 10, 2018 Option Exercise 61,515
Van Naarden Jacob Chief Business Officer Dec 10, 2018 Sale 601,434
Van Naarden Jacob Chief Business Officer Dec 11, 2018 Sale 618,080
Burstein Jennifer Senior VP of Finance Dec 11, 2018 Option Exercise 14,188
Burstein Jennifer Senior VP of Finance Dec 10, 2018 Option Exercise 14,188
Burstein Jennifer Senior VP of Finance Dec 10, 2018 Sale 167,084
Burstein Jennifer Senior VP of Finance Dec 11, 2018 Sale 171,792
Bilenker Joshua H. President & CEO Dec 11, 2018 Option Exercise 136,700
Bilenker Joshua H. President & CEO Dec 10, 2018 Option Exercise 136,700
Bilenker Joshua H. President & CEO Dec 10, 2018 Sale 1,335,198
Bilenker Joshua H. President & CEO Dec 11, 2018 Sale 1,374,237
Van Naarden Jacob Chief Business Officer Nov 27, 2018 Option Exercise 37,031
Van Naarden Jacob Chief Business Officer Nov 26, 2018 Option Exercise 20,064
Van Naarden Jacob Chief Business Officer Nov 26, 2018 Sale 842,224
Van Naarden Jacob Chief Business Officer Nov 27, 2018 Sale 637,481
Burstein Jennifer Senior VP of Finance Nov 27, 2018 Option Exercise 14,188
Burstein Jennifer Senior VP of Finance Nov 26, 2018 Option Exercise 14,188
Burstein Jennifer Senior VP of Finance Nov 26, 2018 Sale 191,356
Burstein Jennifer Senior VP of Finance Nov 27, 2018 Sale 177,850
Bilenker Joshua H. President & CEO Nov 27, 2018 Option Exercise 136,700
Bilenker Joshua H. President & CEO Nov 26, 2018 Option Exercise 85,709
Bilenker Joshua H. President & CEO Nov 26, 2018 Sale 1,531,829
Bilenker Joshua H. President & CEO Nov 27, 2018 Sale 1,413,418
Van Naarden Jacob Chief Business Officer Oct 04, 2018 Option Exercise 16,416
Van Naarden Jacob Chief Business Officer Oct 03, 2018 Option Exercise 20,064
Van Naarden Jacob Chief Business Officer Oct 03, 2018 Sale 919,376
Van Naarden Jacob Chief Business Officer Oct 04, 2018 Sale 731,884
Burstein Jennifer Senior VP of Finance Oct 04, 2018 Option Exercise 14,188
Burstein Jennifer Senior VP of Finance Oct 03, 2018 Option Exercise 14,188
Burstein Jennifer Senior VP of Finance Oct 03, 2018 Sale 208,996
Burstein Jennifer Senior VP of Finance Oct 04, 2018 Sale 203,304
Bilenker Joshua H. President & CEO Oct 04, 2018 Option Exercise 36,480
Bilenker Joshua H. President & CEO Oct 03, 2001 Option Exercise 36,480
Bilenker Joshua H. President & CEO Oct 03, 2018 Sale 1,193,254
Bilenker Joshua H. President & CEO Oct 03, 2001 Sale 479,342
Bilenker Joshua H. President & CEO Oct 04, 2018 Sale 1,626,247
Kunkel Lori Anne Director Oct 01, 2018 Option Exercise 18,240
Kunkel Lori Anne Director Oct 01, 2018 Sale 851,830
Burstein Jennifer Senior VP of Finance Sep 12, 2018 Option Exercise 14,188
Burstein Jennifer Senior VP of Finance Sep 13, 2018 Option Exercise 14,188
Burstein Jennifer Senior VP of Finance Sep 12, 2018 Sale 209,868
Burstein Jennifer Senior VP of Finance Sep 13, 2018 Sale 207,523
Bilenker Joshua H. President & CEO Sep 12, 2018 Option Exercise 11,840
Bilenker Joshua H. President & CEO Sep 13, 2018 Option Exercise 18,067
Bilenker Joshua H. President & CEO Sep 12, 2018 Sale 1,664,159
Bilenker Joshua H. President & CEO Sep 13, 2018 Sale 1,659,806
Van Naarden Jacob Chief Business Officer Sep 12, 2018 Option Exercise 20,064
Van Naarden Jacob Chief Business Officer Sep 13, 2018 Option Exercise 16,416
Van Naarden Jacob Chief Business Officer Sep 12, 2018 Sale 916,277
Van Naarden Jacob Chief Business Officer Sep 13, 2018 Sale 746,903
Van Naarden Jacob Chief Business Officer Aug 13, 2018 Option Exercise 20,064
Van Naarden Jacob Chief Business Officer Aug 14, 2018 Option Exercise 16,416
Van Naarden Jacob Chief Business Officer Aug 13, 2018 Sale 873,804
Van Naarden Jacob Chief Business Officer Aug 14, 2018 Sale 719,642
Burstein Jennifer Senior VP of Finance Aug 13, 2018 Option Exercise 14,188
Burstein Jennifer Senior VP of Finance Aug 14, 2018 Option Exercise 14,188
Burstein Jennifer Senior VP of Finance Aug 13, 2018 Sale 197,827
Burstein Jennifer Senior VP of Finance Aug 14, 2018 Sale 200,279
Bilenker Joshua H. President & CEO Aug 13, 2018 Option Exercise 11,840
Bilenker Joshua H. President & CEO Aug 14, 2018 Option Exercise 11,840
Bilenker Joshua H. President & CEO Aug 13, 2018 Sale 1,589,095
Bilenker Joshua H. President & CEO Aug 14, 2018 Sale 1,599,088
AISLING CAPITAL III LP 10% Owner Jul 10, 2018 Sale 251,201,990
Burstein Jennifer Senior VP of Finance Jul 09, 2018 Option Exercise 17,025
Burstein Jennifer Senior VP of Finance Jul 09, 2018 Sale 280,870
Van Naarden Jacob Chief Business Officer Jul 09, 2018 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Jul 10, 2018 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Jul 10, 2018 Sale 276,907
Van Naarden Jacob Chief Business Officer Jul 09, 2018 Sale 288,631
Bilenker Joshua H. President & CEO Jul 09, 2018 Option Exercise 8,880
Bilenker Joshua H. President & CEO Jul 10, 2018 Option Exercise 8,880
Bilenker Joshua H. President & CEO Jul 10, 2018 Sale 1,347,923
Bilenker Joshua H. President & CEO Jul 09, 2018 Sale 1,404,241
Burstein Jennifer Senior VP of Finance Jun 19, 2018 Option Exercise 19,295
Burstein Jennifer Senior VP of Finance Jun 19, 2018 Sale 300,888
Van Naarden Jacob Chief Business Officer Jun 20, 2018 Option Exercise 49,398
Van Naarden Jacob Chief Business Officer Jun 19, 2018 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Jun 19, 2018 Sale 272,665
Van Naarden Jacob Chief Business Officer Jun 20, 2018 Sale 276,370
Bilenker Joshua H. President & CEO Jun 19, 2018 Option Exercise 8,880
Bilenker Joshua H. President & CEO Jun 20, 2018 Option Exercise 42,032
Bilenker Joshua H. President & CEO Jun 20, 2018 Sale 1,344,406
Bilenker Joshua H. President & CEO Jun 19, 2018 Sale 3,743,353
Bilenker Joshua H. President & CEO Jun 19, 2018 Sale 1,327,768
Bilenker Joshua H. President & CEO Jun 20, 2018 Sale 3,765,835
Kunkel Lori Anne Director Jun 14, 2018 Option Exercise 211,708
Kunkel Lori Anne Director Jun 15, 2018 Sale 1,209,691
Kunkel Lori Anne Director Jun 14, 2018 Sale 5,845,561
MAYLEBEN TIMOTHY M Director Jun 08, 2018 Option Exercise 217,550
MAYLEBEN TIMOTHY M Director Jun 08, 2018 Sale 1,795,470
Fuhrman Alan Director Jun 08, 2018 Option Exercise 29,794
Fuhrman Alan Director Jun 08, 2018 Sale 467,436
Flaherty Keith T. Director Jun 07, 2018 Option Exercise 59,200
Flaherty Keith T. Director Jun 07, 2018 Sale 8,677,032
Van Naarden Jacob Chief Business Officer May 15, 2018 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer May 14, 2018 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer May 15, 2018 Sale 211,566
Van Naarden Jacob Chief Business Officer May 14, 2018 Sale 211,949
Burstein Jennifer Senior VP of Finance May 14, 2018 Option Exercise 19,295
Burstein Jennifer Senior VP of Finance May 14, 2018 Sale 232,784
Bilenker Joshua H. President & CEO May 15, 2018 Option Exercise 8,880
Bilenker Joshua H. President & CEO May 14, 2018 Option Exercise 8,880
Bilenker Joshua H. President & CEO May 15, 2018 Sale 1,030,575
Bilenker Joshua H. President & CEO May 14, 2018 Sale 1,017,071
Burstein Jennifer Senior VP of Finance Apr 24, 2018 Option Exercise 19,295
Burstein Jennifer Senior VP of Finance Apr 24, 2018 Sale 223,804
Van Naarden Jacob Chief Business Officer Apr 24, 2018 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Apr 25, 2018 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Apr 24, 2018 Sale 202,898
Van Naarden Jacob Chief Business Officer Apr 25, 2018 Sale 201,563
Bilenker Joshua H. President & CEO Apr 24, 2018 Option Exercise 8,880
Bilenker Joshua H. President & CEO Apr 25, 2018 Option Exercise 8,880
Bilenker Joshua H. President & CEO Apr 24, 2018 Sale 985,432
Bilenker Joshua H. President & CEO Apr 25, 2018 Sale 981,424
Kunkel Lori Anne Director Apr 20, 2018 Sale 663,379
Burstein Jennifer Senior VP of Finance Mar 13, 2018 Option Exercise 19,295
Burstein Jennifer Senior VP of Finance Mar 13, 2018 Sale 223,262
Van Naarden Jacob Chief Business Officer Mar 13, 2018 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Mar 14, 2018 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Mar 14, 2018 Sale 202,580
Van Naarden Jacob Chief Business Officer Mar 13, 2018 Sale 202,415
Bilenker Joshua H. President & CEO Mar 13, 2018 Option Exercise 8,880
Bilenker Joshua H. President & CEO Mar 14, 2018 Option Exercise 8,880
Bilenker Joshua H. President & CEO Mar 14, 2018 Sale 986,213
Bilenker Joshua H. President & CEO Mar 13, 2018 Sale 986,843
Burstein Jennifer Senior VP of Finance Feb 12, 2018 Option Exercise 19,295
Burstein Jennifer Senior VP of Finance Feb 12, 2018 Sale 158,504
Bilenker Joshua H. President & CEO Feb 12, 2018 Option Exercise 8,880
Bilenker Joshua H. President & CEO Feb 13, 2018 Option Exercise 8,880
Bilenker Joshua H. President & CEO Feb 13, 2018 Sale 748,152
Bilenker Joshua H. President & CEO Feb 12, 2018 Sale 700,377
Van Naarden Jacob Chief Business Officer Feb 12, 2018 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Feb 13, 2018 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Feb 13, 2018 Sale 152,935
Van Naarden Jacob Chief Business Officer Feb 12, 2018 Sale 143,978
Naider Avi Z. Director Jan 22, 2018 Sale 1,500,000
Burstein Jennifer Senior VP of Finance Jan 16, 2018 Option Exercise 17,025
Burstein Jennifer Senior VP of Finance Jan 16, 2018 Sale 131,243
Van Naarden Jacob Chief Business Officer Jan 17, 2018 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Jan 16, 2018 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Jan 17, 2018 Sale 136,065
Van Naarden Jacob Chief Business Officer Jan 16, 2018 Sale 135,802
Bilenker Joshua H. President & CEO Jan 17, 2018 Option Exercise 8,880
Bilenker Joshua H. President & CEO Jan 16, 2018 Option Exercise 8,880
Bilenker Joshua H. President & CEO Jan 17, 2018 Sale 663,584
Bilenker Joshua H. President & CEO Jan 16, 2018 Sale 659,515
MAYLEBEN TIMOTHY M Director Dec 20, 2017 Sale 804,948
AISLING CAPITAL III LP 10% Owner Dec 19, 2017 Sale 20,125,000
Burstein Jennifer Vice President of Finance Dec 14, 2017 Option Exercise 19,295
Burstein Jennifer Vice President of Finance Dec 14, 2017 Sale 141,554
Van Naarden Jacob Chief Business Officer Dec 14, 2017 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Dec 15, 2017 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Dec 14, 2017 Sale 128,319
Van Naarden Jacob Chief Business Officer Dec 15, 2017 Sale 121,921
Bilenker Joshua H. President & CEO Dec 14, 2017 Option Exercise 8,880
Bilenker Joshua H. President & CEO Dec 15, 2017 Option Exercise 8,880
Bilenker Joshua H. President & CEO Dec 14, 2017 Sale 625,120
Bilenker Joshua H. President & CEO Dec 15, 2017 Sale 591,739
Bonita David P Director Dec 08, 2017 Sale 20,625,000
ORBIMED ADVISORS LLC Director Dec 08, 2017 Sale 20,625,000
Burstein Jennifer Vice President of Finance Nov 27, 2017 Option Exercise 19,295
Burstein Jennifer Vice President of Finance Nov 27, 2017 Sale 127,193
Van Naarden Jacob Chief Business Officer Nov 27, 2017 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Nov 28, 2017 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Nov 27, 2017 Sale 115,316
Van Naarden Jacob Chief Business Officer Nov 28, 2017 Sale 114,282
Bilenker Joshua H. President & CEO Nov 27, 2017 Option Exercise 8,880
Bilenker Joshua H. President & CEO Nov 28, 2017 Option Exercise 8,880
Bilenker Joshua H. President & CEO Nov 27, 2017 Sale 560,100
Bilenker Joshua H. President & CEO Nov 28, 2017 Sale 556,648
AISLING CAPITAL III LP 10% Owner Nov 22, 2017 Sale 37,500,000
MAYLEBEN TIMOTHY M Director Nov 22, 2017 Option Exercise 62,730
MAYLEBEN TIMOTHY M Director Nov 22, 2017 Sale 227,563
Bonita David P Director Nov 22, 2017 Sale 20,025,000
ORBIMED ADVISORS LLC Director Nov 22, 2017 Sale 20,025,000
Flaherty Keith T. Director Nov 20, 2017 Sale 550,921
Bonita David P Director Nov 16, 2017 Sale 20,051,389
ORBIMED ADVISORS LLC Director Nov 16, 2017 Sale 20,051,389
Kunkel Lori Anne Director Nov 02, 2017 Sale 424,570
Burstein Jennifer Vice President of Finance Oct 30, 2017 Option Exercise 19,295
Burstein Jennifer Vice President of Finance Oct 30, 2017 Sale 148,219
Van Naarden Jacob Chief Business Officer Oct 30, 2017 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Oct 31, 2017 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Oct 31, 2017 Sale 133,321
Van Naarden Jacob Chief Business Officer Oct 30, 2017 Sale 134,468
Bilenker Joshua H. President & CEO Oct 30, 2017 Option Exercise 8,880
Bilenker Joshua H. President & CEO Oct 31, 2017 Option Exercise 8,880
Bilenker Joshua H. President & CEO Oct 31, 2017 Sale 648,702
Bilenker Joshua H. President & CEO Oct 30, 2017 Sale 653,967
Naider Avi Z. Director Oct 16, 2017 Sale 450,000
Burstein Jennifer Vice President of Finance Sep 18, 2017 Option Exercise 19,295
Burstein Jennifer Vice President of Finance Sep 18, 2017 Sale 151,470
Naider Avi Z. Director Sep 18, 2017 Sale 450,000
Van Naarden Jacob Chief Business Officer Sep 18, 2017 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Sep 19, 2017 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Sep 18, 2017 Sale 137,462
Van Naarden Jacob Chief Business Officer Sep 19, 2017 Sale 136,827
Bilenker Joshua H. President & CEO Sep 18, 2017 Option Exercise 8,880
Bilenker Joshua H. President & CEO Sep 19, 2017 Option Exercise 8,880
Bilenker Joshua H. President & CEO Sep 18, 2017 Sale 669,406
Bilenker Joshua H. President & CEO Sep 19, 2017 Sale 665,870
Naider Avi Z. Director Sep 13, 2017 Sale 450,000
Kunkel Lori Anne Director Aug 22, 2017 Sale 751,731
Flaherty Keith T. Director Aug 21, 2017 Sale 523,883
Burstein Jennifer Vice President of Finance Aug 14, 2017 Option Exercise 19,295
Burstein Jennifer Vice President of Finance Aug 14, 2017 Sale 125,347
Van Naarden Jacob Chief Business Officer Aug 14, 2017 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Aug 15, 2017 Option Exercise 5,622
Van Naarden Jacob Chief Business Officer Aug 14, 2017 Sale 113,619
Van Naarden Jacob Chief Business Officer Aug 15, 2017 Sale 113,134
Bilenker Joshua H. President & CEO Aug 14, 2017 Option Exercise 8,880
Bilenker Joshua H. President & CEO Aug 15, 2017 Option Exercise 8,880
Bilenker Joshua H. President & CEO Aug 14, 2017 Sale 553,006
Bilenker Joshua H. President & CEO Aug 15, 2017 Sale 550,443
Flaherty Keith T. Director May 22, 2017 Sale 326,936
Flaherty Keith T. Director Feb 21, 2017 Sale 300,517
AISLING CAPITAL III LP 10% Owner Jan 10, 2017 Buy 4,960,000
Flaherty Keith T. Director Dec 19, 2016 Sale 219,167
Flaherty Keith T. Director Sep 07, 2016 Sale 435,000
Flaherty Keith T. Director Aug 11, 2016 Sale 389,967
ORBIMED ADVISORS LLC Director Aug 10, 2016 Sale 12,074,224
Bonita David P Director Aug 10, 2016 Sale 12,074,224
AISLING CAPITAL III LP 10% Owner May 17, 2016 Buy 4,999,997
AISLING CAPITAL III LP 10% Owner Dec 11, 2015 Buy 5,500
Naider Avi Z. Director Nov 17, 2015 Buy 99,985
AISLING CAPITAL III LP 10% Owner Nov 17, 2015 Buy 7,022,500
AISLING CAPITAL III LP 10% Owner Nov 13, 2015 Buy 53,704
AISLING CAPITAL III LP 10% Owner Nov 12, 2015 Buy 2,121,319
GOLDSTEIN DOV A MD CFO and Treasurer Apr 02, 2015 Option Exercise 25,629
GOLDSTEIN DOV A MD CFO and Treasurer Apr 01, 2015 Option Exercise 253,249
ORBIMED ADVISORS LLC 10% Owner Aug 06, 2014 Buy 3,580,005
Sonsini Peter W. 10% Owner Aug 06, 2014 Buy 2,999,997
Weller Harry R 10% Owner Aug 06, 2014 Buy 2,999,997
Viswanathan Ravi 10% Owner Aug 06, 2014 Buy 2,999,997
SANDELL SCOTT D 10% Owner Aug 06, 2014 Buy 2,999,997
MOTT DAVID M 10% Owner Aug 06, 2014 Buy 2,999,997
KOLLURI KRISHNA KITTU 10% Owner Aug 06, 2014 Buy 2,999,997
KERINS PATRICK J 10% Owner Aug 06, 2014 Buy 2,999,997
Florence Anthony A. Jr. 10% Owner Aug 06, 2014 Buy 2,999,997
DRANT RYAN D 10% Owner Aug 06, 2014 Buy 2,999,997
BASKETT FOREST 10% Owner Aug 06, 2014 Buy 2,999,997
BARRIS PETER J 10% Owner Aug 06, 2014 Buy 2,999,997
BARRETT M JAMES Director Aug 06, 2014 Buy 2,999,997
New Enterprise Associates 14, L.P. 10% Owner Aug 06, 2013 Buy 2,999,997
Bonita David P Director Aug 06, 2014 Buy 3,580,005
Naider Avi Z. Director Aug 06, 2014 Buy 49,998
GOLDSTEIN DOV A MD CFO and Treasurer Aug 06, 2014 Buy 5,370,001
ELMS STEVE Director Aug 06, 2014 Buy 5,370,001
AISLING CAPITAL III LP 10% Owner Aug 06, 2014 Buy 5,370,001
Flynn James E 10% Owner Aug 06, 2014 Buy 3,998,800
Flynn James E 10% Owner Aug 06, 2014 Buy 3,853,488
Flynn James E 10% Owner Aug 06, 2014 Buy 3,114,020
Flynn James E 10% Owner Aug 06, 2014 Buy 3,206,203