Insider Transactions for GENOMIC HEALTH INC (GHDX)

Owner Relationship Date Transaction Cost # Shares Value($) Total Shares Form 4
Leber Laura Chief Communication Officer Feb 21, 2019 Option Exercise $22.98 1,817 41,755 22,666 Feb 22, 2019, 08:45 PM
Leber Laura Chief Communication Officer Feb 20, 2019 Option Exercise $17.18 18,750 322,125 39,599 Feb 22, 2019, 08:45 PM
Leber Laura Chief Communication Officer Feb 21, 2019 Sale $80.24 5,634 452,076 21,599 Feb 22, 2019, 08:45 PM
Leber Laura Chief Communication Officer Feb 20, 2019 Sale $82.87 18,750 1,553,824 24,120 Feb 22, 2019, 08:45 PM
Radford Jason W. Chief Legal Officer Feb 19, 2019 Sale $83.16 3,508 291,709 35,507 Feb 21, 2019, 07:25 PM
Vaughn James J Chief Commercial Officer Feb 19, 2019 Option Exercise $30.23 1,195 36,130 25,320 Feb 21, 2019, 07:24 PM
Pla Frederic COO Feb 19, 2019 Option Exercise $28.55 5,700 162,714 45,378 Feb 21, 2019, 07:24 PM
Pla Frederic COO Feb 19, 2019 Sale $83.16 9,700 806,661 39,294 Feb 21, 2019, 07:24 PM
Popovits Kimberly J President and CEO Feb 14, 2019 Option Exercise $17.18 47,900 822,922 164,882 Feb 19, 2019, 07:38 PM
Popovits Kimberly J President and CEO Feb 14, 2019 Sale $81.70 47,900 3,913,615 130,882 Feb 19, 2019, 07:38 PM
Cole G Bradley CFO Feb 12, 2019 Option Exercise $21.05 15,000 315,700 58,067 Feb 14, 2019, 05:50 PM
Cole G Bradley CFO Feb 12, 2019 Sale $80.87 15,000 1,213,024 52,132 Feb 14, 2019, 05:50 PM
Vaughn James J Chief Commercial Officer Feb 07, 2019 Option Exercise $31.12 3,000 93,360 27,125 Feb 11, 2019, 07:53 PM
Vaughn James J Chief Commercial Officer Feb 07, 2019 Sale $77.42 3,000 232,272 25,075 Feb 11, 2019, 07:53 PM
Shak Steven Chief Scientific Officer Feb 01, 2019 Option Exercise $22.98 25,000 574,500 364,671 Feb 05, 2019, 05:55 PM
Shak Steven Chief Scientific Officer Feb 04, 2019 Option Exercise $20.66 25,000 516,500 364,671 Feb 05, 2019, 05:55 PM
Shak Steven Chief Scientific Officer Feb 01, 2019 Sale $75.86 25,000 1,896,384 359,331 Feb 05, 2019, 05:55 PM
Shak Steven Chief Scientific Officer Feb 04, 2019 Sale $76.73 25,000 1,918,308 362,479 Feb 05, 2019, 05:55 PM
Shak Steven Chief Scientific Officer Jan 30, 2019 Option Exercise $29.34 25,000 733,500 364,671 Feb 01, 2019, 07:08 PM
Shak Steven Chief Scientific Officer Jan 31, 2019 Option Exercise $29.34 25,000 733,500 364,671 Feb 01, 2019, 07:08 PM
Shak Steven Chief Scientific Officer Jan 30, 2019 Sale $73.49 25,000 1,837,229 361,570 Feb 01, 2019, 07:08 PM
Shak Steven Chief Scientific Officer Jan 31, 2019 Sale $74.98 25,000 1,874,571 362,863 Feb 01, 2019, 07:08 PM
BAKER BROS. ADVISORS LP Director Jan 28, 2019 Sale $71.07 46,477 3,302,980 9,106,199 Jan 30, 2019, 04:00 PM
BAKER BROS. ADVISORS LP Director Jan 24, 2019 Sale $72.02 79,403 5,718,588 9,206,595 Jan 25, 2019, 05:19 PM
BAKER BROS. ADVISORS LP Director Jan 23, 2019 Sale $70.67 37,512 2,651,092 9,273,669 Jan 25, 2019, 05:19 PM
BAKER BROS. ADVISORS LP Director Jan 25, 2019 Sale $72.20 91,916 6,636,648 9,130,859 Jan 25, 2019, 05:19 PM
Radford Jason W. Chief Legal Officer Jan 22, 2019 Sale $71.44 2,963 211,683 32,751 Jan 24, 2019, 06:30 PM
Vaughn James J Chief Commercial Officer Jan 17, 2019 Option Exercise $28.74 2,222 63,854 19,985 Jan 22, 2019, 07:33 PM
BAKER BROS. ADVISORS LP Director Jan 22, 2019 Sale $71.00 51,606 3,664,031 9,302,929 Jan 22, 2019, 05:27 PM
BAKER BROS. ADVISORS LP Director Jan 22, 2019 Sale $71.61 12,800 916,641 9,345,450 Jan 22, 2019, 05:26 PM
BAKER BROS. ADVISORS LP Director Jan 18, 2019 Sale $72.73 177,142 12,884,344 9,369,592 Jan 22, 2019, 05:26 PM
BAKER BROS. ADVISORS LP Director Jan 17, 2019 Sale $70.79 181,747 12,866,124 9,501,955 Jan 22, 2019, 05:26 PM
BAKER BROS. ADVISORS LP Director Jan 14, 2019 Sale $70.07 600 42,043 9,651,709 Jan 14, 2019, 05:11 PM
BAKER BROS. ADVISORS LP Director Jan 11, 2019 Sale $70.22 28,474 1,999,533 9,652,202 Jan 14, 2019, 05:11 PM
BAKER BROS. ADVISORS LP Director Jan 10, 2019 Sale $70.28 10,185 715,780 9,675,664 Jan 14, 2019, 05:11 PM
Cole G Bradley CFO Jan 08, 2019 Option Exercise $21.05 15,000 315,700 54,047 Jan 09, 2019, 07:43 PM
Cole G Bradley CFO Jan 08, 2019 Sale $67.03 15,000 1,005,401 51,947 Jan 09, 2019, 07:43 PM
Vaughn James J Chief Commercial Officer Jan 08, 2019 Option Exercise $31.12 3,000 93,360 20,763 Jan 09, 2019, 07:42 PM
Vaughn James J Chief Commercial Officer Jan 08, 2019 Sale $67.06 3,000 201,181 19,963 Jan 09, 2019, 07:42 PM
Cohen Fred E Director Jan 01, 2019 Option Exercise $64.41 155 9,984 67,619 Jan 03, 2019, 07:13 PM
FUCHS HENRY J Director Jan 01, 2019 Option Exercise $64.41 155 9,984 6,332 Jan 03, 2019, 07:13 PM
GRAHAM GINGER L Director Jan 01, 2019 Option Exercise $64.41 155 9,984 51,803 Jan 03, 2019, 07:12 PM
BAKER BROS. ADVISORS LP Director Jan 01, 2019 Option Exercise $64.41 1,860 119,803 9,684,056 Jan 03, 2019, 12:00 AM
Popovits Kimberly J President and CEO Dec 17, 2018 Sale $66.89 25,000 1,672,242 159,275 Dec 19, 2018, 05:59 PM
Popovits Kimberly J President and CEO Dec 18, 2018 Sale $66.69 25,000 1,667,285 137,912 Dec 19, 2018, 05:59 PM
GRAHAM GINGER L Director Dec 11, 2018 Option Exercise $19.25 24,750 476,438 51,648 Dec 13, 2018, 06:25 PM
Cole G Bradley CFO Dec 11, 2018 Option Exercise $21.05 15,000 315,700 59,047 Dec 13, 2018, 06:24 PM
Cole G Bradley CFO Dec 11, 2018 Sale $71.95 15,000 1,079,219 56,518 Dec 13, 2018, 06:24 PM
BAKER BROS. ADVISORS LP Director Dec 12, 2018 Sale $73.09 18,500 1,352,087 9,683,746 Dec 12, 2018, 05:57 PM
BAKER BROS. ADVISORS LP Director Dec 11, 2018 Sale $74.07 57,554 4,262,823 9,711,616 Dec 12, 2018, 05:57 PM
BAKER BROS. ADVISORS LP Director Dec 10, 2018 Sale $73.83 9,366 691,483 9,746,410 Dec 12, 2018, 05:57 PM
BAKER BROS. ADVISORS LP Director Dec 06, 2018 Sale $75.46 92,679 6,993,622 9,838,546 Dec 07, 2018, 05:16 PM
BAKER BROS. ADVISORS LP Director Dec 07, 2018 Sale $76.15 102,455 7,802,358 9,754,128 Dec 07, 2018, 05:16 PM
BAKER BROS. ADVISORS LP Director Dec 04, 2018 Sale $75.62 32,776 2,478,447 9,941,545 Dec 07, 2018, 05:15 PM
Vaughn James J Chief Commercial Officer Dec 06, 2018 Option Exercise $31.12 3,000 93,360 20,763 Dec 07, 2018, 05:03 PM
Vaughn James J Chief Commercial Officer Dec 06, 2018 Sale $75.30 3,000 225,888 20,463 Dec 07, 2018, 05:03 PM
Shak Steven Chief Scientific Officer Dec 03, 2018 Option Exercise $17.33 1,500 25,995 338,241 Dec 06, 2018, 07:47 PM
Shak Steven Chief Scientific Officer Dec 03, 2018 Sale $78.18 1,500 117,273 338,128 Dec 06, 2018, 07:47 PM
BAKER BROS. ADVISORS LP Director Dec 03, 2018 Sale $78.49 202,134 15,865,833 10,063,808 Dec 03, 2018, 05:40 PM
BAKER BROS. ADVISORS LP Director Nov 30, 2018 Sale $79.20 204,757 16,217,023 10,237,588 Dec 03, 2018, 05:39 PM
BAKER BROS. ADVISORS LP Director Nov 29, 2018 Sale $77.95 51,278 3,997,192 10,307,436 Dec 03, 2018, 05:39 PM
BAKER BROS. ADVISORS LP Director Nov 28, 2018 Sale $75.61 250,392 18,932,284 10,468,980 Nov 28, 2018, 05:44 PM
BAKER BROS. ADVISORS LP Director Nov 27, 2018 Sale $74.09 138,610 10,269,089 10,562,396 Nov 28, 2018, 05:42 PM
BAKER BROS. ADVISORS LP Director Nov 26, 2018 Sale $74.28 39,675 2,947,113 10,648,158 Nov 28, 2018, 05:42 PM
BAKER BROS. ADVISORS LP Director Nov 16, 2018 Sale $76.65 87,395 6,699,000 10,728,010 Nov 20, 2018, 05:06 PM
Popovits Kimberly J President and CEO Nov 16, 2018 Sale $76.72 10,000 767,171 171,127 Nov 20, 2018, 04:45 PM
Popovits Kimberly J President and CEO Nov 15, 2018 Option Exercise $22.98 25,000 574,500 201,982 Nov 19, 2018, 09:27 PM
Popovits Kimberly J President and CEO Nov 16, 2018 Option Exercise $22.98 15,000 344,700 191,982 Nov 19, 2018, 09:27 PM
Popovits Kimberly J President and CEO Nov 15, 2018 Sale $77.18 25,000 1,929,560 196,982 Nov 19, 2018, 09:27 PM
Popovits Kimberly J President and CEO Nov 16, 2018 Sale $76.72 15,000 1,150,793 183,321 Nov 19, 2018, 09:27 PM
Cole G Bradley CFO Nov 13, 2018 Option Exercise $19.60 8,576 168,076 53,948 Nov 15, 2018, 04:04 PM
Cole G Bradley CFO Nov 13, 2018 Sale $79.18 8,576 679,027 51,131 Nov 15, 2018, 04:04 PM
Shak Steven Chief Scientific Officer Nov 09, 2018 Option Exercise $17.33 5,500 95,315 342,241 Nov 14, 2018, 08:13 PM
Shak Steven Chief Scientific Officer Nov 09, 2018 Sale $83.21 5,500 457,646 339,484 Nov 14, 2018, 08:13 PM
BAKER BROS. ADVISORS LP Director Nov 13, 2018 Sale $79.69 114,858 9,153,058 10,786,282 Nov 13, 2018, 06:35 PM
BAKER BROS. ADVISORS LP Director Nov 13, 2018 Sale $78.50 138,712 10,889,359 10,938,575 Nov 13, 2018, 06:33 PM
BAKER BROS. ADVISORS LP Director Nov 12, 2018 Sale $81.07 65,588 5,317,265 11,000,100 Nov 13, 2018, 06:33 PM
BAKER BROS. ADVISORS LP Director Nov 12, 2018 Sale $80.38 14,415 1,158,724 11,007,633 Nov 13, 2018, 06:32 PM
BAKER BROS. ADVISORS LP Director Nov 09, 2018 Sale $82.51 169,344 13,972,201 11,150,887 Nov 13, 2018, 06:32 PM
BAKER BROS. ADVISORS LP Director Nov 09, 2018 Sale $83.71 107,738 9,018,337 11,243,695 Nov 13, 2018, 06:29 PM
Vaughn James J Chief Commercial Officer Nov 08, 2018 Option Exercise $31.12 3,000 93,360 20,542 Nov 13, 2018, 06:29 PM
Vaughn James J Chief Commercial Officer Nov 08, 2018 Sale $85.18 3,000 255,545 19,442 Nov 13, 2018, 06:29 PM
Cohen Fred E Director Nov 08, 2018 Option Exercise $27.75 10,000 277,500 77,464 Nov 13, 2018, 06:27 PM
Cohen Fred E Director Nov 08, 2018 Sale $87.93 10,000 879,262 76,628 Nov 13, 2018, 06:27 PM
BAKER BROS. ADVISORS LP Director Nov 08, 2018 Sale $86.50 76,273 6,597,504 11,280,104 Nov 13, 2018, 06:26 PM
BAKER BROS. ADVISORS LP Director Nov 08, 2018 Sale $85.58 72,745 6,225,158 11,354,802 Nov 13, 2018, 06:22 PM
Pla Frederic COO Nov 07, 2018 Option Exercise $27.08 43,500 1,177,796 79,038 Nov 09, 2018, 04:02 PM
Pla Frederic COO Nov 07, 2018 Sale $84.91 43,500 3,693,589 76,938 Nov 09, 2018, 04:02 PM
Popovits Kimberly J President and CEO Oct 15, 2018 Option Exercise $22.98 25,000 574,500 201,982 Oct 17, 2018, 05:52 PM
Popovits Kimberly J President and CEO Oct 16, 2018 Option Exercise $22.98 25,000 574,500 201,982 Oct 17, 2018, 05:52 PM
Popovits Kimberly J President and CEO Oct 16, 2018 Sale $66.26 25,000 1,656,524 199,187 Oct 17, 2018, 05:52 PM
Popovits Kimberly J President and CEO Oct 15, 2018 Sale $64.31 25,000 1,607,641 178,262 Oct 17, 2018, 05:52 PM
Shak Steven Chief Scientific Officer Oct 09, 2018 Option Exercise $17.33 5,500 95,315 342,241 Oct 11, 2018, 07:59 PM
Shak Steven Chief Scientific Officer Oct 09, 2018 Sale $64.35 5,500 353,950 337,841 Oct 11, 2018, 07:59 PM
Cole G Bradley CFO Oct 10, 2018 Option Exercise $17.18 5,000 85,900 50,372 Oct 11, 2018, 07:58 PM
Cole G Bradley CFO Oct 10, 2018 Sale $63.19 5,000 315,955 48,021 Oct 11, 2018, 07:58 PM
Pla Frederic COO Oct 08, 2018 Option Exercise $27.00 1,500 40,500 37,038 Oct 10, 2018, 06:04 PM
Pla Frederic COO Oct 08, 2018 Sale $65.43 1,500 98,148 35,938 Oct 10, 2018, 06:04 PM
Vaughn James J Chief Commercial Officer Oct 09, 2018 Option Exercise $27.50 25,000 687,560 42,542 Oct 10, 2018, 06:02 PM
Vaughn James J Chief Commercial Officer Oct 08, 2018 Option Exercise $30.41 25,000 760,154 42,542 Oct 10, 2018, 06:02 PM
Vaughn James J Chief Commercial Officer Oct 08, 2018 Sale $65.34 25,000 1,633,518 26,327 Oct 10, 2018, 06:02 PM
Vaughn James J Chief Commercial Officer Oct 09, 2018 Sale $64.37 25,000 1,609,325 23,272 Oct 10, 2018, 06:02 PM
FUCHS HENRY J Director Oct 01, 2018 Option Exercise $70.18 142 9,966 6,177 Oct 03, 2018, 08:32 PM
Cohen Fred E Director Oct 01, 2018 Option Exercise $70.18 142 9,966 67,464 Oct 03, 2018, 08:13 PM
GRAHAM GINGER L Director Oct 01, 2018 Option Exercise $70.18 142 9,966 26,898 Oct 03, 2018, 08:12 PM
BAKER BROS. ADVISORS LP Director Oct 01, 2018 Option Exercise $70.18 1,704 119,587 11,370,600 Oct 03, 2018, 07:43 PM
Cole G Bradley COO Sep 11, 2018 Option Exercise $17.18 5,000 85,900 50,372 Sep 13, 2018, 06:48 PM
Cole G Bradley COO Sep 11, 2018 Sale $64.01 5,000 320,074 46,972 Sep 13, 2018, 06:48 PM
Pla Frederic Chief Bus & Prod Dev Officer Sep 10, 2018 Option Exercise $27.00 1,500 40,500 37,038 Sep 11, 2018, 07:40 PM
Pla Frederic Chief Bus & Prod Dev Officer Sep 10, 2018 Sale $62.98 1,500 94,467 35,938 Sep 11, 2018, 07:40 PM
Shak Steven Chief Scientific Officer Sep 10, 2018 Option Exercise $27.33 5,500 150,315 342,241 Sep 11, 2018, 07:38 PM
Shak Steven Chief Scientific Officer Sep 10, 2018 Sale $63.05 5,500 346,794 338,604 Sep 11, 2018, 07:38 PM
Cohen Fred E Director Sep 06, 2018 Option Exercise $34.44 8,250 284,130 75,572 Sep 10, 2018, 05:02 PM
Cohen Fred E Director Sep 06, 2018 Sale $61.51 8,250 507,453 67,322 Sep 10, 2018, 05:02 PM
Popovits Kimberly J President and CEO Aug 14, 2018 Sale $52.60 60,000 3,156,203 228,532 Aug 16, 2018, 04:23 PM
Shak Steven Chief Scientific Officer Aug 09, 2018 Option Exercise $17.33 5,500 95,315 342,241 Aug 10, 2018, 06:47 PM
Shak Steven Chief Scientific Officer Aug 09, 2018 Sale $55.92 5,500 307,576 339,241 Aug 10, 2018, 06:47 PM
Pla Frederic Chief Bus & Prod Dev Officer Aug 09, 2018 Option Exercise $27.00 1,500 40,500 41,038 Aug 10, 2018, 06:45 PM
Pla Frederic Chief Bus & Prod Dev Officer Aug 09, 2018 Sale $55.93 5,500 307,625 40,238 Aug 10, 2018, 06:45 PM
Cole G Bradley COO Aug 09, 2018 Option Exercise $17.18 8,529 146,528 53,901 Aug 10, 2018, 06:41 PM
Cole G Bradley COO Aug 09, 2018 Sale $55.94 8,529 477,105 49,390 Aug 10, 2018, 06:41 PM
Cole G Bradley COO Mar 08, 2017 Option Exercise $23.31 100 2,331 39,828 Aug 10, 2018, 06:39 PM
Radford Jason W. Chief Legal Officer Aug 08, 2018 Sale $56.39 4,126 232,681 34,750 Aug 10, 2018, 06:36 PM
Cohen Fred E Director Aug 07, 2018 Option Exercise $25.79 8,250 212,768 75,572 Aug 09, 2018, 07:47 PM
Cohen Fred E Director Aug 07, 2018 Sale $56.22 8,250 463,800 68,722 Aug 09, 2018, 07:47 PM
GRAHAM GINGER L Director Aug 06, 2018 Option Exercise $17.33 16,500 285,945 26,756 Aug 08, 2018, 04:28 PM
Popovits Kimberly J President and CEO Jul 16, 2018 Option Exercise $17.18 10,000 171,800 246,157 Jul 18, 2018, 04:40 PM
Popovits Kimberly J President and CEO Jul 16, 2018 Sale $53.27 10,000 532,685 243,158 Jul 18, 2018, 04:40 PM
Shak Steven Chief Scientific Officer Jul 09, 2018 Option Exercise $17.33 5,500 95,315 341,416 Jul 10, 2018, 05:18 PM
Shak Steven Chief Scientific Officer Jul 09, 2018 Sale $49.56 5,500 272,554 335,916 Jul 10, 2018, 05:18 PM
Cohen Fred E Director Jul 01, 2018 Option Exercise $50.40 198 9,979 67,322 Jul 03, 2018, 04:03 PM
GRAHAM GINGER L Director Jul 01, 2018 Option Exercise $50.40 198 9,979 10,256 Jul 03, 2018, 04:02 PM
FUCHS HENRY J Director Jul 01, 2018 Option Exercise $50.40 198 9,979 6,035 Jul 03, 2018, 04:01 PM
BAKER BROS. ADVISORS LP Director Jul 01, 2018 Option Exercise $50.40 2,376 119,750 11,370,316 Jul 03, 2018, 12:00 AM
Popovits Kimberly J President and CEO Jun 14, 2018 Option Exercise $17.18 10,000 171,800 246,157 Jun 18, 2018, 07:16 PM
Popovits Kimberly J President and CEO Jun 14, 2018 Sale $48.89 10,000 488,916 236,557 Jun 18, 2018, 07:16 PM
Shak Steven Chief Scientific Officer Jun 11, 2018 Option Exercise $17.33 5,500 95,315 341,416 Jun 13, 2018, 06:59 PM
Shak Steven Chief Scientific Officer Jun 11, 2018 Sale $50.22 5,500 276,200 336,425 Jun 13, 2018, 06:59 PM
Vaughn James J Chief Commercial Officer Jun 04, 2018 Option Exercise $25.98 80,768 2,097,997 49,655 Jun 06, 2018, 07:57 PM
Vaughn James J Chief Commercial Officer Jun 04, 2018 Sale $45.78 93,414 4,276,165 42,103 Jun 06, 2018, 07:57 PM
Radford Jason W. Chief Legal Officer May 15, 2018 Option Exercise $38.00 1,153 43,814 37,667 May 16, 2018, 08:23 PM
Popovits Kimberly J President and CEO May 14, 2018 Option Exercise $17.18 10,000 171,800 246,157 May 16, 2018, 06:41 PM
Popovits Kimberly J President and CEO May 14, 2018 Sale $38.09 10,000 380,877 241,157 May 16, 2018, 06:41 PM
Shak Steven Chief Scientific Officer May 09, 2018 Option Exercise $17.33 5,500 95,315 341,416 May 11, 2018, 03:10 PM
Shak Steven Chief Scientific Officer May 09, 2018 Sale $36.64 5,500 201,543 338,491 May 11, 2018, 03:10 PM
Vaughn James J Chief Commercial Officer May 02, 2018 Sale $32.50 1,497 48,653 29,655 May 04, 2018, 08:59 PM
Popovits Kimberly J President and CEO Apr 16, 2018 Option Exercise $17.18 15,000 257,700 251,157 Apr 18, 2018, 04:33 PM
Popovits Kimberly J President and CEO Apr 16, 2018 Sale $33.19 15,000 497,880 236,157 Apr 18, 2018, 04:33 PM
FUCHS HENRY J Director Apr 01, 2018 Option Exercise $31.29 319 9,982 5,837 Apr 03, 2018, 08:32 PM
Cohen Fred E Director Apr 01, 2018 Option Exercise $31.29 319 9,982 67,124 Apr 03, 2018, 08:32 PM
GRAHAM GINGER L Director Apr 01, 2018 Option Exercise $31.29 319 9,982 10,058 Apr 03, 2018, 08:31 PM
BAKER BROS. ADVISORS LP Director Apr 01, 2018 Option Exercise $31.29 3,828 119,778 11,369,920 Apr 03, 2018, 06:01 PM
Popovits Kimberly J President and CEO Mar 14, 2018 Option Exercise $17.18 5,000 85,900 241,157 Mar 16, 2018, 06:54 PM
Popovits Kimberly J President and CEO Mar 14, 2018 Sale $32.01 5,000 160,048 236,157 Mar 16, 2018, 06:54 PM
Cole G Bradley COO Mar 13, 2018 Option Exercise $17.33 5,000 86,650 49,754 Mar 15, 2018, 04:31 PM
Cole G Bradley COO Mar 13, 2018 Sale $32.80 5,000 164,014 45,054 Mar 15, 2018, 04:31 PM
BAKER BROS. ADVISORS LP Director Mar 09, 2018 Option Exercise $18.50 49,500 915,750 11,369,282 Mar 12, 2018, 06:04 PM
Leber Laura Chief Communication Officer Feb 20, 2018 Sale $32.92 3,374 111,080 16,731 Feb 22, 2018, 04:24 PM
Febbo Phillip G. Chief Medical Officer Feb 20, 2018 Sale $32.84 4,942 162,290 21,687 Feb 22, 2018, 04:19 PM
Cole G Bradley COO Feb 20, 2018 Option Exercise $17.33 5,000 86,650 49,754 Feb 22, 2018, 04:19 PM
Cole G Bradley COO Feb 20, 2018 Sale $32.89 5,000 164,474 44,954 Feb 22, 2018, 04:19 PM
Pla Frederic Chief Bus & Prod Dev Officer Feb 15, 2018 Option Exercise $32.66 3,600 117,576 38,712 Feb 20, 2018, 06:40 PM
Radford Jason W. Chief Legal Officer Feb 15, 2018 Option Exercise $32.66 2,065 67,443 38,820 Feb 20, 2018, 05:59 PM
McEachron Kim Chief People Officer Feb 15, 2018 Option Exercise $32.66 2,221 72,538 33,727 Feb 20, 2018, 05:59 PM
Leber Laura Chief Communication Officer Feb 15, 2018 Option Exercise $32.66 1,999 65,287 19,905 Feb 20, 2018, 05:58 PM
Febbo Phillip G. Chief Medical Officer Feb 15, 2018 Option Exercise $32.66 2,801 91,481 26,329 Feb 20, 2018, 05:57 PM
Vaughn James J Chief Commercial Officer Feb 15, 2018 Option Exercise $32.66 3,115 101,736 31,152 Feb 20, 2018, 05:56 PM
Pla Frederic Chief Bus & Prod Dev Officer Feb 15, 2018 Option Exercise $32.66 3,600 117,576 38,712 Feb 20, 2018, 05:55 PM
Shak Steven Chief Scientific Officer Feb 15, 2018 Option Exercise $32.66 2,825 92,264 335,916 Feb 20, 2018, 05:55 PM
Cole G Bradley COO Feb 15, 2018 Option Exercise $32.66 3,182 103,924 44,754 Feb 20, 2018, 05:54 PM
Popovits Kimberly J President and CEO Feb 15, 2018 Option Exercise $32.66 6,232 203,537 59,617 Feb 20, 2018, 05:53 PM
Popovits Kimberly J President and CEO Feb 14, 2018 Option Exercise $17.18 10,000 171,800 75,849 Feb 15, 2018, 04:02 PM
Popovits Kimberly J President and CEO Feb 14, 2018 Sale $32.93 10,000 329,336 65,849 Feb 15, 2018, 04:02 PM
Popovits Kimberly J President and CEO Jan 16, 2018 Option Exercise $17.18 10,000 171,800 51,719 Jan 18, 2018, 09:30 PM
Popovits Kimberly J President and CEO Jan 16, 2018 Sale $34.99 10,000 349,885 41,919 Jan 18, 2018, 09:30 PM
Cole G Bradley COO Jan 09, 2018 Option Exercise $17.33 5,000 86,650 45,346 Jan 10, 2018, 09:17 PM
Cole G Bradley COO Jan 09, 2018 Sale $35.51 5,000 177,565 40,346 Jan 10, 2018, 09:17 PM
Vaughn James J Chief Commercial Officer Jan 02, 2018 Option Exercise $17.33 2,169 37,589 30,481 Jan 04, 2018, 07:54 PM
Vaughn James J Chief Commercial Officer Jan 02, 2018 Sale $34.09 3,004 102,406 28,312 Jan 04, 2018, 07:54 PM
Cohen Fred E Director Jan 01, 2018 Option Exercise $34.20 292 9,986 66,805 Jan 03, 2018, 06:22 PM
FUCHS HENRY J Director Jan 01, 2018 Option Exercise $34.20 292 9,986 5,518 Jan 03, 2018, 06:22 PM
GRAHAM GINGER L Director Jan 01, 2018 Option Exercise $34.20 292 9,986 9,739 Jan 03, 2018, 06:21 PM
BAKER BROS. ADVISORS LP Director Jan 01, 2018 Option Exercise $34.20 3,504 119,837 11,361,032 Jan 03, 2018, 12:00 AM
Febbo Phillip G. Chief Medical Officer Dec 19, 2017 Option Exercise $27.00 5,000 135,000 23,134 Dec 20, 2017, 04:35 PM
Febbo Phillip G. Chief Medical Officer Dec 19, 2017 Sale $36.99 5,334 197,298 18,134 Dec 20, 2017, 04:35 PM
Leber Laura Chief Communication Officer Dec 14, 2017 Option Exercise $21.52 12,000 258,240 27,754 Dec 18, 2017, 07:52 PM
Leber Laura Chief Communication Officer Dec 15, 2017 Option Exercise $17.33 9,000 155,970 24,754 Dec 18, 2017, 07:52 PM
Leber Laura Chief Communication Officer Dec 14, 2017 Sale $32.00 12,000 384,000 15,754 Dec 18, 2017, 07:52 PM
Leber Laura Chief Communication Officer Dec 15, 2017 Sale $35.00 9,000 315,000 15,754 Dec 18, 2017, 07:52 PM
Popovits Kimberly J President and CEO Dec 14, 2017 Option Exercise $17.28 20,000 345,535 61,919 Dec 18, 2017, 07:51 PM
Popovits Kimberly J President and CEO Dec 14, 2017 Sale $31.50 20,000 630,000 51,919 Dec 18, 2017, 07:51 PM
Cole G Bradley COO Dec 12, 2017 Option Exercise $17.33 5,000 86,650 45,346 Dec 14, 2017, 07:03 PM
Cole G Bradley COO Dec 12, 2017 Sale $29.94 5,000 149,708 40,346 Dec 14, 2017, 07:03 PM
Cole G Bradley COO Dec 12, 2017 Option Exercise $17.33 5,000 86,650 44,935 Dec 13, 2017, 04:14 PM
Cole G Bradley COO Dec 12, 2017 Sale $29.94 5,000 149,708 39,935 Dec 13, 2017, 04:14 PM
Cole G Bradley COO Nov 07, 2017 Option Exercise $17.33 5,000 86,650 44,935 Nov 09, 2017, 04:59 PM
Cole G Bradley COO Nov 07, 2017 Sale $31.47 5,000 157,330 39,935 Nov 09, 2017, 04:59 PM
Vaughn James J Chief Commercial Officer Nov 01, 2017 Option Exercise $17.33 3,907 67,708 33,692 Nov 08, 2017, 05:29 PM
Vaughn James J Chief Commercial Officer Nov 02, 2017 Option Exercise $17.33 924 16,013 28,999 Nov 08, 2017, 05:29 PM
Vaughn James J Chief Commercial Officer Nov 01, 2017 Sale $32.58 5,617 183,001 31,282 Nov 08, 2017, 05:29 PM
Vaughn James J Chief Commercial Officer Nov 02, 2017 Sale $32.51 1,379 44,827 28,175 Nov 08, 2017, 05:29 PM
Cole G Bradley COO Oct 10, 2017 Option Exercise $17.33 5,000 86,650 44,935 Oct 11, 2017, 05:55 PM
Cole G Bradley COO Oct 10, 2017 Sale $31.93 5,000 159,636 39,935 Oct 11, 2017, 05:55 PM
FUCHS HENRY J Director Oct 01, 2017 Option Exercise $32.09 311 9,980 5,226 Oct 03, 2017, 06:17 PM
Cohen Fred E Director Oct 01, 2017 Option Exercise $32.09 311 9,980 66,513 Oct 03, 2017, 06:16 PM
GRAHAM GINGER L Director Oct 01, 2017 Option Exercise $32.09 311 9,980 9,447 Oct 03, 2017, 06:15 PM
BAKER BROS. ADVISORS LP Director Oct 01, 2017 Option Exercise $32.09 3,732 119,760 11,360,448 Oct 03, 2017, 05:39 PM
Popovits Kimberly J President and CEO Sep 14, 2017 Option Exercise $17.33 5,000 86,650 46,132 Sep 18, 2017, 04:02 PM
Popovits Kimberly J President and CEO Sep 14, 2017 Sale $31.00 5,000 154,989 41,132 Sep 18, 2017, 04:02 PM
Cole G Bradley COO Sep 12, 2017 Option Exercise $17.33 5,000 86,650 44,935 Sep 14, 2017, 05:12 PM
Cole G Bradley COO Sep 12, 2017 Sale $31.86 5,000 159,288 39,935 Sep 14, 2017, 05:12 PM
Popovits Kimberly J President and CEO Aug 14, 2017 Option Exercise $17.33 5,000 86,650 84,057 Aug 16, 2017, 08:02 PM
Popovits Kimberly J President and CEO Aug 14, 2017 Sale $30.22 5,000 151,111 79,057 Aug 16, 2017, 08:02 PM
Vaughn James J Chief Commercial Officer Aug 08, 2017 Option Exercise $23.31 6,500 151,515 37,785 Aug 09, 2017, 07:52 PM
Vaughn James J Chief Commercial Officer Aug 08, 2017 Sale $30.59 8,000 244,724 29,785 Aug 09, 2017, 07:52 PM
Cole G Bradley COO Aug 08, 2017 Option Exercise $17.33 5,000 86,650 44,935 Aug 09, 2017, 07:51 PM
Cole G Bradley COO Aug 08, 2017 Sale $30.57 5,000 152,845 39,935 Aug 09, 2017, 07:51 PM
Febbo Phillip G. Chief Medical Officer Jul 19, 2017 Sale $33.57 3,174 106,538 18,130 Jul 21, 2017, 04:20 PM
Cole G Bradley COO Jul 11, 2017 Option Exercise $17.33 5,000 86,650 44,935 Jul 13, 2017, 05:23 PM
Cole G Bradley COO Jul 11, 2017 Sale $32.53 5,000 162,667 40,008 Jul 13, 2017, 05:23 PM
Popovits Kimberly J President and CEO Jul 03, 2017 Option Exercise $17.33 3,532 61,210 82,589 Jul 06, 2017, 07:28 PM
Popovits Kimberly J President and CEO Jul 05, 2017 Option Exercise $17.33 1,468 25,440 80,525 Jul 06, 2017, 07:28 PM
Popovits Kimberly J President and CEO Jul 05, 2017 Sale $32.67 1,468 47,952 79,057 Jul 06, 2017, 07:28 PM
Popovits Kimberly J President and CEO Jul 03, 2017 Sale $32.56 3,532 114,988 79,057 Jul 06, 2017, 07:28 PM
FUCHS HENRY J Director Jul 01, 2017 Option Exercise $32.55 307 9,993 4,915 Jul 05, 2017, 07:04 PM
Cohen Fred E Director Jul 01, 2017 Option Exercise $32.55 307 9,993 66,202 Jul 05, 2017, 07:03 PM
GRAHAM GINGER L Director Jul 01, 2017 Option Exercise $32.55 307 9,993 9,136 Jul 05, 2017, 07:03 PM
BAKER BROS. ADVISORS LP Director Jul 01, 2017 Option Exercise $32.55 3,684 119,914 11,359,826 Jul 05, 2017, 06:19 PM
Shak Steven Chief Scientific Officer Jun 23, 2017 Option Exercise $23.31 5,000 116,550 336,924 Jun 27, 2017, 06:11 PM
Shak Steven Chief Scientific Officer Jun 23, 2017 Sale $33.27 5,000 166,371 331,924 Jun 27, 2017, 06:11 PM
Cole G Bradley COO Jun 13, 2017 Option Exercise $17.33 5,000 86,650 44,935 Jun 15, 2017, 04:40 PM
Cole G Bradley COO Jun 13, 2017 Sale $31.67 5,000 158,342 39,935 Jun 15, 2017, 04:40 PM
Popovits Kimberly J President and CEO Jun 05, 2017 Option Exercise $17.33 5,000 86,650 84,057 Jun 07, 2017, 07:07 PM
Popovits Kimberly J President and CEO Jun 05, 2017 Sale $32.32 5,000 161,582 79,057 Jun 07, 2017, 07:07 PM
BAKER BROS. ADVISORS LP Director May 31, 2017 Option Exercise $18.13 49,500 897,435 11,359,212 Jun 01, 2017, 05:19 PM
Shak Steven Chief Scientific Officer May 23, 2017 Option Exercise $23.31 5,000 116,550 336,103 May 25, 2017, 04:39 PM
Shak Steven Chief Scientific Officer May 23, 2017 Sale $29.40 5,000 146,981 331,103 May 25, 2017, 04:39 PM
Cohen Fred E Director May 19, 2017 Option Exercise $14.37 8,250 118,552 74,145 May 23, 2017, 08:16 PM
Cohen Fred E Director May 19, 2017 Sale $29.54 8,250 243,745 65,895 May 23, 2017, 08:16 PM
Cohen Fred E Director May 18, 2017 Option Exercise $18.05 16,500 297,743 82,395 May 22, 2017, 06:59 PM
Cohen Fred E Director May 18, 2017 Sale $29.88 16,500 493,040 65,895 May 22, 2017, 06:59 PM
Cohen Fred E Director May 16, 2017 Option Exercise $18.13 8,250 149,572 74,145 May 18, 2017, 07:52 PM
Cohen Fred E Director May 16, 2017 Sale $30.68 8,250 253,102 65,895 May 18, 2017, 07:52 PM
Radford Jason W. Chief Legal Officer May 15, 2017 Option Exercise $30.81 1,253 38,605 24,902 May 17, 2017, 07:42 PM
Popovits Kimberly J President and CEO May 03, 2017 Option Exercise $17.33 5,000 86,650 83,236 May 04, 2017, 05:12 PM
Popovits Kimberly J President and CEO May 03, 2017 Sale $31.77 5,000 158,849 80,529 May 04, 2017, 05:12 PM
Shak Steven Chief Scientific Officer Apr 24, 2017 Option Exercise $23.31 5,000 116,550 336,103 Apr 26, 2017, 05:09 PM
Shak Steven Chief Scientific Officer Apr 24, 2017 Sale $31.46 5,000 157,323 331,103 Apr 26, 2017, 05:09 PM
Popovits Kimberly J President and CEO Apr 03, 2017 Option Exercise $20.80 5,000 103,992 83,236 Apr 05, 2017, 05:25 PM
Popovits Kimberly J President and CEO Apr 03, 2017 Sale $31.30 5,000 156,507 78,236 Apr 05, 2017, 05:25 PM
BAKER BROS. ADVISORS LP Director Apr 01, 2017 Option Exercise $31.49 3,804 119,788 11,350,962 Apr 04, 2017, 07:32 PM
FUCHS HENRY J Director Apr 01, 2017 Option Exercise $31.49 317 9,982 4,608 Apr 04, 2017, 05:28 PM
Cohen Fred E Director Apr 01, 2017 Option Exercise $31.49 317 9,982 65,895 Apr 04, 2017, 05:27 PM
GRAHAM GINGER L Director Apr 01, 2017 Option Exercise $31.49 317 9,982 8,829 Apr 04, 2017, 05:26 PM
Shak Steven Chief Scientific Officer Mar 23, 2017 Option Exercise $23.31 5,000 116,550 336,103 Mar 24, 2017, 07:05 PM
Shak Steven Chief Scientific Officer Mar 23, 2017 Sale $31.26 5,000 156,294 331,103 Mar 24, 2017, 07:05 PM
Leber Laura Chief Communication Officer Mar 20, 2017 Sale $31.88 3,072 97,941 14,627 Mar 22, 2017, 04:03 PM
Cole G Bradley COO Mar 08, 2017 Option Exercise $23.31 5,710 133,100 45,338 Mar 10, 2017, 06:21 PM
Cole G Bradley COO Mar 08, 2017 Sale $31.55 5,710 180,134 39,728 Mar 10, 2017, 06:21 PM
Popovits Kimberly J President and CEO Mar 06, 2017 Option Exercise $23.31 290 6,760 78,526 Mar 07, 2017, 08:34 PM
Popovits Kimberly J President and CEO Mar 03, 2017 Option Exercise $23.31 4,710 109,790 82,946 Mar 07, 2017, 08:34 PM
Popovits Kimberly J President and CEO Mar 06, 2017 Sale $31.08 290 9,014 78,236 Mar 07, 2017, 08:34 PM
Popovits Kimberly J President and CEO Mar 03, 2017 Sale $31.09 4,710 146,440 78,236 Mar 07, 2017, 08:34 PM
Shak Steven Chief Scientific Officer Feb 23, 2017 Option Exercise $23.31 5,000 116,550 336,103 Feb 27, 2017, 09:56 PM
Shak Steven Chief Scientific Officer Feb 23, 2017 Sale $29.36 5,000 146,815 331,103 Feb 27, 2017, 09:56 PM
Vaughn James J Chief Commercial Officer Feb 15, 2017 Option Exercise $31.12 3,417 106,337 30,502 Feb 17, 2017, 06:51 PM
Shak Steven Chief Scientific Officer Feb 15, 2017 Option Exercise $31.12 2,884 89,750 331,103 Feb 17, 2017, 06:50 PM
Radford Jason W. Chief Legal Officer Feb 15, 2017 Option Exercise $31.12 771 23,994 26,155 Feb 17, 2017, 06:49 PM
Popovits Kimberly J President and CEO Feb 15, 2017 Option Exercise $31.12 4,982 155,040 78,236 Feb 17, 2017, 06:48 PM
Pla Frederic Chief Bus & Prod Dev Officer Feb 15, 2017 Option Exercise $31.12 2,882 89,688 31,700 Feb 17, 2017, 06:47 PM
McEachron Kim Chief People Officer Feb 15, 2017 Option Exercise $31.12 2,197 68,371 27,620 Feb 17, 2017, 06:46 PM
Leber Laura Chief Communication Officer Feb 15, 2017 Option Exercise $31.12 2,078 64,667 17,699 Feb 17, 2017, 06:45 PM
Febbo Phillip G. Chief Medical Officer Feb 15, 2017 Option Exercise $31.12 1,910 59,439 23,139 Feb 17, 2017, 06:44 PM
Febbo Phillip G. Chief Medical Officer Feb 16, 2017 Sale $30.09 2,495 75,064 21,870 Feb 17, 2017, 06:44 PM
Cole G Bradley COO Feb 15, 2017 Option Exercise $31.12 3,294 102,509 39,728 Feb 17, 2017, 06:43 PM
Cole G Bradley COO Feb 15, 2017 Option Exercise $23.31 5,000 116,550 48,022 Feb 17, 2017, 06:43 PM
Cole G Bradley COO Feb 15, 2017 Sale $29.00 5,000 145,000 43,022 Feb 17, 2017, 06:43 PM
Shak Steven Chief Scientific Officer Jan 23, 2017 Option Exercise $23.31 5,000 116,550 332,207 Jan 25, 2017, 08:01 PM
Shak Steven Chief Scientific Officer Jan 23, 2017 Sale $27.28 5,000 136,387 327,207 Jan 25, 2017, 08:01 PM
Cole G Bradley COO Jan 10, 2017 Option Exercise $23.31 5,000 116,550 40,882 Jan 12, 2017, 05:39 PM
Cole G Bradley COO Jan 10, 2017 Sale $29.22 5,000 146,087 35,882 Jan 12, 2017, 05:39 PM
GRAHAM GINGER L Director Jan 01, 2017 Option Exercise $29.39 340 9,993 8,512 Jan 04, 2017, 07:19 PM
FUCHS HENRY J Director Jan 01, 2017 Option Exercise $29.39 340 9,993 4,291 Jan 04, 2017, 07:18 PM
Cohen Fred E Director Jan 01, 2017 Option Exercise $29.39 340 9,993 65,578 Jan 04, 2017, 07:17 PM
BAKER FELIX Director Jan 01, 2017 Option Exercise $29.39 4,080 119,911 11,350,328 Jan 04, 2017, 06:30 PM
Radford Jason W. Chief Legal Officer May 15, 2016 Option Exercise $27.28 1,420 38,738 14,554 Dec 20, 2016, 05:15 PM
Febbo Phillip G. Chief Medical Officer Aug 15, 2015 Option Exercise $24.85 1,065 26,465 14,307 Dec 20, 2016, 05:14 PM
Febbo Phillip G. Chief Medical Officer Aug 15, 2016 Option Exercise $27.00 1,066 28,782 13,241 Dec 20, 2016, 05:14 PM
Cole G Bradley COO Dec 06, 2016 Option Exercise $23.31 5,000 116,550 40,882 Dec 08, 2016, 08:12 PM
Cole G Bradley COO Dec 06, 2016 Sale $30.61 5,000 153,029 35,882 Dec 08, 2016, 08:12 PM
Popovits Kimberly J President and CEO Dec 05, 2016 Option Exercise $23.31 5,000 116,550 64,620 Dec 06, 2016, 07:17 PM
Popovits Kimberly J President and CEO Dec 05, 2016 Sale $30.02 5,000 150,100 59,620 Dec 06, 2016, 07:17 PM
Leber Laura Chief Communication Officer Nov 21, 2016 Option Exercise $17.41 3,600 62,676 21,399 Nov 23, 2016, 02:43 PM
Leber Laura Chief Communication Officer Nov 21, 2016 Sale $31.73 7,068 224,266 17,799 Nov 23, 2016, 02:43 PM
Shak Steven Chief Scientific Officer Nov 10, 2016 Option Exercise $18.89 5,000 94,450 330,534 Nov 15, 2016, 04:56 PM
Shak Steven Chief Scientific Officer Nov 10, 2016 Sale $31.71 5,000 158,569 327,207 Nov 15, 2016, 04:56 PM
Cole G Bradley COO Nov 08, 2016 Option Exercise $23.31 5,000 116,550 40,426 Nov 10, 2016, 07:37 PM
Cole G Bradley COO Nov 08, 2016 Sale $29.68 5,000 148,422 35,426 Nov 10, 2016, 07:37 PM
Popovits Kimberly J President and CEO Nov 03, 2016 Option Exercise $18.89 5,313 100,363 64,933 Nov 07, 2016, 06:53 PM
Popovits Kimberly J President and CEO Nov 03, 2016 Sale $28.88 5,313 153,423 59,620 Nov 07, 2016, 06:53 PM
Shak Steven Chief Scientific Officer Oct 11, 2016 Option Exercise $18.89 5,000 94,450 332,207 Oct 12, 2016, 07:24 PM
Shak Steven Chief Scientific Officer Oct 11, 2016 Sale $30.39 5,000 151,925 327,207 Oct 12, 2016, 07:24 PM
Cole G Bradley COO Oct 10, 2016 Option Exercise $21.18 8,290 175,560 39,716 Oct 12, 2016, 06:07 PM
Cole G Bradley COO Oct 10, 2016 Sale $30.59 8,290 253,572 35,426 Oct 12, 2016, 06:07 PM
Vaughn James J Chief Commercial Officer Oct 06, 2016 Sale $29.68 3,000 89,042 26,079 Oct 11, 2016, 08:07 PM
GRAHAM GINGER L Director Oct 01, 2016 Option Exercise $28.92 345 9,977 8,172 Oct 04, 2016, 07:46 PM
FUCHS HENRY J Director Oct 01, 2016 Option Exercise $28.92 345 9,977 3,951 Oct 04, 2016, 07:44 PM
Cohen Fred E Director Oct 01, 2016 Option Exercise $28.92 345 9,977 65,238 Oct 04, 2016, 07:43 PM
BAKER FELIX Director Sep 30, 2016 Option Exercise $28.92 4,140 119,729 11,349,648 Oct 04, 2016, 06:35 PM
Shak Steven Chief Scientific Officer Sep 13, 2016 Option Exercise $18.89 5,000 94,450 332,207 Sep 15, 2016, 06:25 PM
Shak Steven Chief Scientific Officer Sep 13, 2016 Sale $26.83 5,000 134,156 327,207 Sep 15, 2016, 06:25 PM
Cole G Bradley COO Sep 06, 2016 Option Exercise $18.89 4,000 75,560 39,426 Sep 08, 2016, 06:36 PM
Cole G Bradley COO Sep 06, 2016 Sale $27.41 4,000 109,637 35,426 Sep 08, 2016, 06:36 PM
Shak Steven Chief Scientific Officer Aug 23, 2016 Option Exercise $18.89 5,000 94,450 332,207 Aug 25, 2016, 06:49 PM
Shak Steven Chief Scientific Officer Aug 23, 2016 Sale $27.24 5,000 136,215 327,207 Aug 25, 2016, 06:49 PM
Cole G Bradley COO Aug 11, 2016 Option Exercise $18.89 5,000 94,450 40,426 Aug 15, 2016, 06:03 PM
Cole G Bradley COO Aug 11, 2016 Sale $28.87 5,000 144,374 35,426 Aug 15, 2016, 06:03 PM
BAKER FELIX Director Aug 15, 2016 Buy $27.02 100,000 2,701,590 11,348,958 Aug 15, 2016, 06:02 PM
Vaughn James J Chief Commercial Officer Aug 08, 2016 Sale $28.74 3,000 86,221 29,079 Aug 10, 2016, 07:09 PM
Shak Steven Chief Scientific Officer Jul 19, 2016 Option Exercise $18.89 5,000 94,450 332,207 Jul 22, 2016, 04:13 PM
Shak Steven Chief Scientific Officer Jul 19, 2016 Sale $27.42 5,000 137,111 327,207 Jul 22, 2016, 04:13 PM
Cole G Bradley COO Jul 06, 2016 Option Exercise $18.89 5,000 94,450 40,426 Jul 08, 2016, 05:05 PM
Cole G Bradley COO Jul 06, 2016 Sale $26.64 5,000 133,223 35,426 Jul 08, 2016, 05:05 PM
GRAHAM GINGER L Director Jul 01, 2016 Option Exercise $26.74 373 9,974 7,827 Jul 06, 2016, 06:44 PM
FUCHS HENRY J Director Jul 01, 2016 Option Exercise $26.74 373 9,974 3,606 Jul 06, 2016, 06:43 PM
Cohen Fred E Director Jul 01, 2016 Option Exercise $26.74 373 9,974 64,893 Jul 06, 2016, 06:42 PM
BAKER FELIX Director Jul 01, 2016 Option Exercise $26.74 4,476 119,688 11,259,062 Jul 06, 2016, 06:22 PM
Shak Steven Chief Scientific Officer Jun 21, 2016 Option Exercise $18.89 5,000 94,450 332,207 Jun 23, 2016, 04:14 PM
Shak Steven Chief Scientific Officer Jun 21, 2016 Sale $25.77 5,000 128,859 327,307 Jun 23, 2016, 04:14 PM
Cole G Bradley COO Jun 09, 2016 Option Exercise $18.89 5,000 94,450 40,426 Jun 13, 2016, 04:13 PM
Cole G Bradley COO Jun 09, 2016 Sale $26.62 5,000 133,118 35,626 Jun 13, 2016, 04:13 PM
Vaughn James J Chief Commercial Officer Jun 06, 2016 Option Exercise $18.89 1,997 37,723 34,076 Jun 08, 2016, 04:49 PM
Vaughn James J Chief Commercial Officer Jun 06, 2016 Sale $28.00 1,997 55,916 32,079 Jun 08, 2016, 04:49 PM
BAKER FELIX Director May 17, 2016 Option Exercise $10.73 49,500 531,135 11,258,316 May 19, 2016, 06:23 PM
Cole G Bradley COO May 16, 2016 Option Exercise $18.89 5,000 94,450 39,970 May 18, 2016, 07:34 PM
Cole G Bradley COO May 16, 2016 Sale $27.60 5,000 137,994 34,970 May 18, 2016, 07:34 PM
Febbo Phillip G. Chief Medical Officer May 10, 2016 Sale $27.20 6,324 172,034 15,113 May 12, 2016, 04:57 PM
Vaughn James J Chief Commercial Officer May 09, 2016 Option Exercise $18.89 2,000 37,780 33,255 May 11, 2016, 04:42 PM
Vaughn James J Chief Commercial Officer May 09, 2016 Sale $28.00 2,000 56,000 31,255 May 11, 2016, 04:42 PM
Shak Steven Chief Scientific Officer May 04, 2016 Option Exercise $18.89 10,000 188,900 336,383 May 06, 2016, 06:13 PM
Shak Steven Chief Scientific Officer May 04, 2016 Sale $25.43 10,000 254,296 326,383 May 06, 2016, 06:13 PM
BAKER FELIX Director Apr 01, 2016 Option Exercise $25.48 4,704 119,858 11,250,066 Apr 05, 2016, 05:58 PM
GRAHAM GINGER L Director Apr 01, 2016 Option Exercise $25.48 392 9,988 7,454 Apr 04, 2016, 09:00 PM
FUCHS HENRY J Director Apr 01, 2016 Option Exercise $25.48 392 9,988 3,233 Apr 04, 2016, 08:59 PM
Cohen Fred E Director Apr 01, 2016 Option Exercise $25.48 392 9,988 64,520 Apr 04, 2016, 08:58 PM
Vaughn James J Chief Commercial Officer Feb 15, 2016 Option Exercise $26.53 3,371 89,433 20,705 Feb 17, 2016, 08:51 PM
Shak Steven EVP of R&D Feb 15, 2016 Option Exercise $26.53 2,795 74,151 318,073 Feb 17, 2016, 08:50 PM
Pla Frederic Chief Bus & Prod Dev Officer Feb 15, 2016 Option Exercise $26.53 1,580 41,917 15,068 Feb 17, 2016, 08:46 PM
McEachron Kim Chief People Officer Feb 15, 2016 Option Exercise $26.53 1,961 52,025 15,473 Feb 17, 2016, 08:45 PM
Leber Laura Chief Communication Officer Feb 15, 2016 Option Exercise $26.53 2,093 55,527 10,866 Feb 17, 2016, 08:44 PM
Febbo Phillip G. Chief Medical Officer Feb 15, 2016 Option Exercise $26.53 1,255 33,295 14,047 Feb 17, 2016, 08:43 PM
Popovits Kimberly J President and CEO Feb 15, 2016 Option Exercise $26.53 3,195 84,763 32,496 Feb 17, 2016, 08:20 PM
Cole G Bradley COO Feb 15, 2016 Option Exercise $26.53 3,008 79,802 24,420 Feb 17, 2016, 08:07 PM
Vaughn James J Chief Commercial Officer Feb 09, 2016 Option Exercise $18.89 3 57 24,079 Feb 11, 2016, 04:24 PM
Vaughn James J Chief Commercial Officer Feb 09, 2016 Sale $28.00 3 84 24,076 Feb 11, 2016, 04:24 PM
LIVINGSTON RANDALL S Director Jan 13, 2016 Option Exercise $10.73 1,250 13,412 7,399 Jan 15, 2016, 05:17 PM
LIVINGSTON RANDALL S Director Jan 13, 2016 Sale $32.14 1,250 40,175 6,149 Jan 15, 2016, 05:17 PM
Popovits Kimberly J President and CEO Jan 12, 2016 Option Exercise $18.89 5,000 94,450 40,691 Jan 14, 2016, 04:58 PM
Popovits Kimberly J President and CEO Jan 12, 2016 Sale $30.34 5,000 151,679 35,691 Jan 14, 2016, 04:58 PM
Cole G Bradley COO Jan 12, 2016 Option Exercise $18.89 4,000 75,560 31,428 Jan 14, 2016, 04:56 PM
Cole G Bradley COO Jan 12, 2016 Sale $31.69 4,000 126,771 30,886 Jan 14, 2016, 04:56 PM
Vaughn James J Chief Commercial Officer Jan 07, 2016 Option Exercise $18.89 2,000 37,780 26,076 Jan 08, 2016, 04:13 PM
Vaughn James J Chief Commercial Officer Jan 07, 2016 Sale $33.63 2,000 67,265 24,076 Jan 08, 2016, 04:13 PM
BAKER FELIX Director Jan 01, 2016 Option Exercise $35.20 3,408 119,962 11,249,282 Jan 05, 2016, 06:47 PM
FUCHS HENRY J Director Jan 01, 2016 Option Exercise $35.20 284 9,997 2,841 Jan 05, 2016, 04:20 PM
GRAHAM GINGER L Director Jan 01, 2016 Option Exercise $35.20 284 9,997 7,062 Jan 05, 2016, 04:18 PM
Cohen Fred E Director Jan 01, 2016 Option Exercise $35.20 284 9,997 64,128 Jan 05, 2016, 04:17 PM
Popovits Kimberly J President and CEO Dec 15, 2015 Option Exercise $18.89 5,000 94,450 40,691 Dec 17, 2015, 04:47 PM
Popovits Kimberly J President and CEO Dec 15, 2015 Sale $30.00 5,000 150,000 35,691 Dec 17, 2015, 04:47 PM
Cole G Bradley COO Dec 08, 2015 Option Exercise $18.89 4,000 75,560 34,428 Dec 10, 2015, 04:47 PM
Cole G Bradley COO Dec 08, 2015 Sale $29.26 4,000 117,030 30,428 Dec 10, 2015, 04:47 PM
Leber Laura Chief Communication Officer Dec 07, 2015 Option Exercise $10.15 4,200 42,630 17,159 Dec 09, 2015, 03:03 PM
Leber Laura Chief Communication Officer Dec 07, 2015 Sale $29.33 4,200 123,202 12,959 Dec 09, 2015, 03:03 PM
Vaughn James J Chief Commercial Officer Dec 07, 2015 Option Exercise $18.89 2,000 37,780 26,076 Dec 09, 2015, 03:02 PM
Vaughn James J Chief Commercial Officer Dec 07, 2015 Sale $29.33 2,000 58,668 24,076 Dec 09, 2015, 03:02 PM
Cole G Bradley COO Nov 10, 2015 Option Exercise $18.89 4,000 75,560 34,326 Nov 12, 2015, 04:08 PM
Cole G Bradley COO Nov 10, 2015 Sale $26.03 4,000 104,128 30,326 Nov 12, 2015, 04:08 PM
BAKER FELIX Director Oct 01, 2015 Option Exercise $21.34 5,616 119,845 11,248,714 Oct 05, 2015, 07:17 PM
GRAHAM GINGER L Director Oct 01, 2015 Option Exercise $21.34 468 9,987 6,778 Oct 05, 2015, 05:04 PM
FUCHS HENRY J Director Oct 01, 2015 Option Exercise $21.34 468 9,987 2,557 Oct 05, 2015, 05:02 PM
Cohen Fred E Director Oct 01, 2015 Option Exercise $21.34 468 9,987 63,844 Oct 05, 2015, 05:01 PM
Cole G Bradley COO Sep 08, 2015 Option Exercise $9.39 6,000 56,340 36,326 Sep 10, 2015, 04:38 PM
Cole G Bradley COO Sep 09, 2015 Option Exercise $9.39 3,664 34,405 33,990 Sep 10, 2015, 04:38 PM
Cole G Bradley COO Sep 09, 2015 Sale $25.40 3,664 93,056 30,326 Sep 10, 2015, 04:38 PM
Cole G Bradley COO Sep 08, 2015 Sale $25.32 6,000 151,929 30,326 Sep 10, 2015, 04:38 PM
Cole G Bradley COO Jul 07, 2015 Option Exercise $9.39 4,000 37,560 34,326 Jul 09, 2015, 07:25 PM
Cole G Bradley COO Jul 07, 2015 Sale $27.53 4,000 110,112 30,326 Jul 09, 2015, 07:25 PM
BAKER FELIX Director Jul 01, 2015 Option Exercise $27.34 4,380 119,749 11,247,778 Jul 06, 2015, 05:42 PM
GRAHAM GINGER L Director Jul 01, 2015 Option Exercise $27.34 365 9,979 6,310 Jul 06, 2015, 05:06 PM
FUCHS HENRY J Director Jul 01, 2015 Option Exercise $27.34 365 9,979 2,089 Jul 06, 2015, 05:04 PM
Cohen Fred E Director Jul 01, 2015 Option Exercise $27.34 365 9,979 63,376 Jul 06, 2015, 05:03 PM
Cole G Bradley COO Jun 09, 2015 Option Exercise $9.39 4,000 37,560 34,326 Jun 11, 2015, 05:34 PM
Cole G Bradley COO Jun 09, 2015 Sale $26.24 4,000 104,965 30,326 Jun 11, 2015, 05:34 PM
Cole G Bradley COO May 12, 2015 Option Exercise $9.39 4,000 37,560 33,658 May 14, 2015, 04:51 PM
Cole G Bradley COO May 12, 2015 Sale $27.54 4,000 110,157 31,558 May 14, 2015, 04:51 PM
Popovits Kimberly J President and CEO Apr 13, 2015 Option Exercise $18.89 3,000 56,670 37,939 Apr 15, 2015, 04:57 PM
Popovits Kimberly J President and CEO Apr 13, 2015 Sale $31.28 3,000 93,840 34,939 Apr 15, 2015, 04:57 PM
Cole G Bradley COO Apr 07, 2015 Option Exercise $9.39 4,000 37,560 33,658 Apr 09, 2015, 04:16 PM
Cole G Bradley COO Apr 07, 2015 Sale $30.44 4,000 121,747 29,658 Apr 09, 2015, 04:16 PM
GRAHAM GINGER L Director Apr 01, 2015 Option Exercise $30.43 328 9,981 5,945 Apr 03, 2015, 04:23 PM
FUCHS HENRY J Director Apr 01, 2015 Option Exercise $30.43 328 9,981 1,724 Apr 03, 2015, 04:22 PM
Cohen Fred E Director Apr 01, 2015 Option Exercise $30.43 328 9,981 63,011 Apr 03, 2015, 04:21 PM
BAKER FELIX Director Apr 01, 2015 Option Exercise $30.43 3,936 119,772 11,247,048 Apr 02, 2015, 06:37 PM
Popovits Kimberly J President and CEO Mar 12, 2015 Option Exercise $18.89 3,000 56,670 37,939 Mar 17, 2015, 05:50 PM
Popovits Kimberly J President and CEO Mar 12, 2015 Sale $31.91 3,000 95,717 34,939 Mar 17, 2015, 05:50 PM
Cole G Bradley COO Mar 10, 2015 Option Exercise $9.39 4,000 37,560 33,658 Mar 12, 2015, 04:05 PM
Cole G Bradley COO Mar 10, 2015 Sale $31.84 4,000 127,376 30,058 Mar 12, 2015, 04:05 PM
Cole G Bradley COO Feb 15, 2015 Option Exercise $31.12 2,827 87,976 29,658 Feb 18, 2015, 09:48 PM
Popovits Kimberly J President and CEO Feb 12, 2015 Option Exercise $18.89 3,000 56,670 39,965 Feb 17, 2015, 07:12 PM
Popovits Kimberly J President and CEO Feb 12, 2015 Sale $29.86 3,000 89,566 36,965 Feb 17, 2015, 07:12 PM
Cole G Bradley COO Feb 10, 2015 Option Exercise $9.39 4,000 37,560 25,645 Feb 12, 2015, 05:30 PM
Cole G Bradley COO Feb 10, 2015 Sale $31.37 4,000 125,468 21,645 Feb 12, 2015, 05:30 PM
LIVINGSTON RANDALL S Director Feb 02, 2015 Option Exercise $10.73 1,000 10,730 7,149 Feb 04, 2015, 04:58 PM
LIVINGSTON RANDALL S Director Feb 02, 2015 Sale $31.93 1,000 31,931 6,149 Feb 04, 2015, 04:58 PM
Popovits Kimberly J President and CEO Jan 12, 2015 Option Exercise $18.89 3,000 56,670 39,965 Jan 14, 2015, 04:34 PM
Popovits Kimberly J President and CEO Jan 12, 2015 Sale $33.46 3,000 100,386 36,965 Jan 14, 2015, 04:34 PM
BAKER FELIX Director Jan 01, 2015 Option Exercise $31.97 3,744 119,696 11,246,392 Jan 05, 2015, 05:45 PM
GRAHAM GINGER L Director Jan 01, 2015 Option Exercise $31.97 312 9,975 5,617 Jan 05, 2015, 04:29 PM
Cohen Fred E Director Jan 01, 2015 Option Exercise $31.97 312 9,975 62,683 Jan 05, 2015, 04:27 PM
FUCHS HENRY J Director Jan 01, 2015 Option Exercise $31.97 312 9,975 1,396 Jan 05, 2015, 04:26 PM
Popovits Kimberly J President and CEO Dec 11, 2014 Option Exercise $18.89 3,000 56,670 39,365 Dec 15, 2014, 04:13 PM
Popovits Kimberly J President and CEO Dec 11, 2014 Sale $32.99 3,000 98,967 36,965 Dec 15, 2014, 04:13 PM
Cole G Bradley COO Dec 08, 2014 Option Exercise $9.39 4,336 40,715 25,981 Dec 09, 2014, 04:25 PM
Cole G Bradley COO Dec 08, 2014 Sale $32.52 4,336 141,004 21,645 Dec 09, 2014, 04:25 PM
Popovits Kimberly J President and CEO Nov 12, 2014 Option Exercise $18.89 4,300 81,227 39,165 Nov 14, 2014, 07:07 PM
Popovits Kimberly J President and CEO Nov 12, 2014 Sale $34.82 4,300 149,709 36,965 Nov 14, 2014, 07:07 PM
Cole G Bradley COO Nov 10, 2014 Option Exercise $9.39 4,000 37,560 26,891 Nov 12, 2014, 04:32 PM
Cole G Bradley COO Nov 10, 2014 Sale $35.35 4,000 141,388 22,891 Nov 12, 2014, 04:32 PM
LIVINGSTON RANDALL S Director Nov 03, 2014 Option Exercise $10.73 3,000 32,190 9,149 Nov 05, 2014, 05:01 PM
LIVINGSTON RANDALL S Director Nov 03, 2014 Sale $36.24 3,000 108,718 6,149 Nov 05, 2014, 05:01 PM
Popovits Kimberly J President and CEO Oct 13, 2014 Option Exercise $18.89 3,000 56,670 39,965 Oct 15, 2014, 04:22 PM
Popovits Kimberly J President and CEO Oct 13, 2014 Sale $30.78 3,000 92,326 36,965 Oct 15, 2014, 04:22 PM
Cole G Bradley COO Oct 08, 2014 Option Exercise $9.39 4,000 37,560 26,891 Oct 10, 2014, 04:19 PM
Cole G Bradley COO Oct 08, 2014 Sale $28.77 4,000 115,098 22,891 Oct 10, 2014, 04:19 PM
BAKER FELIX Director Oct 01, 2014 Option Exercise $28.54 4,200 119,868 11,245,768 Oct 03, 2014, 05:56 PM
GRAHAM GINGER L Director Oct 01, 2014 Option Exercise $28.54 350 9,989 5,305 Oct 03, 2014, 04:30 PM
FUCHS HENRY J Director Oct 01, 2014 Option Exercise $28.54 350 9,989 1,084 Oct 03, 2014, 04:28 PM
COLELLA SAMUEL D Director Oct 01, 2014 Option Exercise $28.54 350 9,989 5,305 Oct 03, 2014, 04:27 PM
Cohen Fred E Director Oct 01, 2014 Option Exercise $28.54 350 9,989 62,371 Oct 03, 2014, 04:26 PM
Popovits Kimberly J President and CEO Sep 11, 2014 Option Exercise $16.95 3,000 50,846 39,965 Sep 15, 2014, 04:16 PM
Popovits Kimberly J President and CEO Sep 11, 2014 Sale $29.82 3,000 89,446 36,965 Sep 15, 2014, 04:16 PM
Cole G Bradley COO Sep 08, 2014 Option Exercise $8.42 4,700 39,576 27,591 Sep 10, 2014, 06:04 PM
Cole G Bradley COO Sep 08, 2014 Sale $30.09 4,700 141,429 22,891 Sep 10, 2014, 06:04 PM
Shak Steven EVP of R&D Aug 13, 2014 Option Exercise $2.88 7,000 20,160 319,298 Aug 15, 2014, 05:21 PM
Shak Steven EVP of R&D Aug 14, 2014 Option Exercise $2.88 6,348 18,282 318,646 Aug 15, 2014, 05:21 PM
Shak Steven EVP of R&D Aug 14, 2014 Sale $27.49 6,348 174,498 312,298 Aug 15, 2014, 05:21 PM
Shak Steven EVP of R&D Aug 13, 2014 Sale $27.25 7,000 190,726 312,298 Aug 15, 2014, 05:21 PM
Popovits Kimberly J President and CEO Aug 12, 2014 Option Exercise $9.39 3,000 28,170 39,965 Aug 14, 2014, 04:54 PM
Popovits Kimberly J President and CEO Aug 12, 2014 Sale $26.07 3,000 78,201 36,965 Aug 14, 2014, 04:54 PM
Popovits Kimberly J President and CEO Jul 14, 2014 Option Exercise $9.39 3,000 28,170 39,965 Jul 16, 2014, 04:17 PM
Popovits Kimberly J President and CEO Jul 14, 2014 Sale $26.59 3,000 79,777 36,965 Jul 16, 2014, 04:17 PM
Cole G Bradley COO Jul 08, 2014 Option Exercise $2.88 2,300 6,624 25,191 Jul 10, 2014, 04:19 PM
Cole G Bradley COO Jul 08, 2014 Sale $27.05 2,300 62,209 22,891 Jul 10, 2014, 04:19 PM
Shak Steven EVP of R&D Jul 01, 2014 Option Exercise $2.88 7,000 20,160 319,298 Jul 03, 2014, 06:04 PM
Shak Steven EVP of R&D Jul 01, 2014 Sale $27.00 7,000 188,970 312,298 Jul 03, 2014, 06:04 PM
GRAHAM GINGER L Director Jul 01, 2014 Option Exercise $27.86 358 9,974 4,955 Jul 03, 2014, 04:35 PM
FUCHS HENRY J Director Jul 01, 2014 Option Exercise $27.86 358 9,974 734 Jul 03, 2014, 04:33 PM
COLELLA SAMUEL D Director Jul 01, 2014 Option Exercise $27.86 358 9,974 4,955 Jul 03, 2014, 04:32 PM
Cohen Fred E Director Jul 01, 2014 Option Exercise $27.86 358 9,974 62,021 Jul 03, 2014, 04:31 PM
BAKER FELIX Director Jul 01, 2014 Option Exercise $27.86 4,296 119,687 11,245,068 Jul 03, 2014, 02:33 PM
Shak Steven EVP of R&D Jun 12, 2014 Option Exercise $2.88 7,000 20,160 319,298 Jun 16, 2014, 06:08 PM
Shak Steven EVP of R&D Jun 12, 2014 Sale $26.73 7,000 187,107 316,398 Jun 16, 2014, 06:08 PM
Popovits Kimberly J President and CEO Jun 12, 2014 Option Exercise $9.39 3,000 28,170 39,965 Jun 16, 2014, 06:03 PM
Popovits Kimberly J President and CEO Jun 12, 2014 Sale $26.10 3,000 78,295 36,965 Jun 16, 2014, 06:03 PM
Schorno Dean L CFO Jun 10, 2014 Option Exercise $18.03 4,000 72,140 28,524 Jun 13, 2014, 08:07 PM
Schorno Dean L CFO Jun 10, 2014 Sale $27.62 4,000 110,487 24,524 Jun 13, 2014, 08:07 PM
Cole G Bradley COO Jun 09, 2014 Option Exercise $2.88 2,337 6,731 25,228 Jun 11, 2014, 05:48 PM
Cole G Bradley COO Jun 09, 2014 Sale $27.29 2,337 63,767 22,891 Jun 11, 2014, 05:48 PM
Popovits Kimberly J President and CEO May 12, 2014 Option Exercise $9.39 3,000 28,170 39,255 May 14, 2014, 04:04 PM
Popovits Kimberly J President and CEO May 12, 2014 Sale $26.54 3,000 79,617 36,646 May 14, 2014, 04:04 PM
Schorno Dean L CFO May 09, 2014 Option Exercise $18.03 4,000 72,140 27,814 May 13, 2014, 04:05 PM
Schorno Dean L CFO May 09, 2014 Sale $25.09 4,000 100,359 23,814 May 13, 2014, 04:05 PM
Shak Steven EVP of R&D Apr 14, 2014 Option Exercise $2.88 7,000 20,160 318,547 Apr 16, 2014, 04:19 PM
Shak Steven EVP of R&D Apr 14, 2014 Sale $26.25 7,000 183,734 311,588 Apr 16, 2014, 04:19 PM
Cole G Bradley COO Apr 08, 2014 Option Exercise $2.88 3,000 8,640 25,226 Apr 10, 2014, 04:20 PM
Cole G Bradley COO Apr 08, 2014 Sale $27.00 3,000 81,000 22,226 Apr 10, 2014, 04:20 PM
BAKER FELIX Director Apr 01, 2014 Option Exercise $26.57 4,512 119,884 11,244,352 Apr 03, 2014, 07:22 PM
FUCHS HENRY J Director Apr 01, 2014 Option Exercise $26.57 376 9,990 376 Apr 03, 2014, 05:54 PM
GRAHAM GINGER L Director Apr 01, 2014 Option Exercise $26.57 376 9,990 4,597 Apr 03, 2014, 04:00 PM
COLELLA SAMUEL D Director Apr 01, 2014 Option Exercise $26.57 376 9,990 4,597 Apr 03, 2014, 03:59 PM
Cohen Fred E Director Apr 01, 2014 Option Exercise $26.57 376 9,990 61,663 Apr 03, 2014, 03:57 PM
Shak Steven EVP of R&D Mar 14, 2014 Option Exercise $2.88 7,000 20,160 318,588 Mar 18, 2014, 05:39 PM
Shak Steven EVP of R&D Mar 14, 2014 Sale $28.36 7,000 198,493 311,588 Mar 18, 2014, 05:39 PM
Cole G Bradley COO Mar 10, 2014 Option Exercise $2.88 3,000 8,640 25,226 Mar 12, 2014, 04:59 PM
Cole G Bradley COO Mar 10, 2014 Sale $27.76 3,000 83,290 22,226 Mar 12, 2014, 04:59 PM
HIBBS KATHY L SVP & General Counsel Feb 15, 2014 Option Exercise $27.62 2,602 71,867 18,679 Feb 19, 2014, 07:16 PM
HIBBS KATHY L SVP & General Counsel Feb 18, 2014 Sale $27.88 1,312 36,584 15,787 Feb 19, 2014, 07:16 PM
Popovits Kimberly J President and CEO Feb 15, 2014 Option Exercise $27.62 3,611 99,736 38,636 Feb 19, 2014, 07:15 PM
Cole G Bradley COO Feb 15, 2014 Option Exercise $27.62 2,563 70,790 23,817 Feb 19, 2014, 07:14 PM
Schorno Dean L CFO Feb 15, 2014 Option Exercise $27.62 1,593 43,999 24,836 Feb 19, 2014, 07:13 PM
Shak Steven EVP of R&D Feb 15, 2014 Option Exercise $27.62 2,055 56,759 312,971 Feb 19, 2014, 07:11 PM
Shak Steven EVP of R&D Feb 14, 2014 Option Exercise $2.88 7,000 20,160 320,643 Feb 19, 2014, 07:11 PM
Shak Steven EVP of R&D Feb 14, 2014 Sale $27.38 7,000 191,630 313,643 Feb 19, 2014, 07:11 PM
Cole G Bradley COO Feb 10, 2014 Option Exercise $2.88 3,000 8,640 27,789 Feb 12, 2014, 04:51 PM
Cole G Bradley COO Feb 10, 2014 Sale $27.00 3,000 81,000 24,789 Feb 12, 2014, 04:51 PM
Shak Steven EVP of R&D Jan 15, 2014 Option Exercise $2.88 7,000 20,160 315,283 Jan 17, 2014, 01:39 PM
Shak Steven EVP of R&D Jan 15, 2014 Sale $31.51 7,000 220,601 308,283 Jan 17, 2014, 01:39 PM
Popovits Kimberly J President and CEO Jan 13, 2014 Option Exercise $9.39 2,500 23,475 29,366 Jan 15, 2014, 10:26 AM
Popovits Kimberly J President and CEO Jan 13, 2014 Sale $30.00 2,500 75,000 26,866 Jan 15, 2014, 10:26 AM
Cole G Bradley COO Jan 08, 2014 Option Exercise $2.88 3,000 8,640 21,369 Jan 10, 2014, 03:50 PM
Cole G Bradley COO Jan 08, 2014 Sale $28.17 3,000 84,501 18,369 Jan 10, 2014, 03:50 PM
GRAHAM GINGER L Director Jan 01, 2014 Option Exercise $29.27 341 9,981 4,221 Jan 03, 2014, 07:05 PM
COLELLA SAMUEL D Director Jan 01, 2014 Option Exercise $29.27 341 9,981 4,221 Jan 03, 2014, 07:04 PM
Cohen Fred E Director Jan 01, 2014 Option Exercise $29.27 341 9,981 61,287 Jan 03, 2014, 07:03 PM
BAKER FELIX Director Jan 01, 2014 Option Exercise $29.27 4,092 119,773 11,243,600 Jan 03, 2014, 05:29 PM
Shak Steven EVP of R&D & CMO Dec 16, 2013 Option Exercise $2.88 7,000 20,160 315,283 Dec 18, 2013, 01:45 PM
Shak Steven EVP of R&D & CMO Dec 17, 2013 Option Exercise $2.88 7,000 20,160 315,283 Dec 18, 2013, 01:45 PM
Shak Steven EVP of R&D & CMO Dec 16, 2013 Sale $29.91 7,000 209,350 308,283 Dec 18, 2013, 01:45 PM
Shak Steven EVP of R&D & CMO Dec 17, 2013 Sale $29.24 7,000 204,671 308,283 Dec 18, 2013, 01:45 PM
Popovits Kimberly J President and CEO Dec 12, 2013 Option Exercise $9.39 2,500 23,475 29,366 Dec 16, 2013, 02:34 PM
Popovits Kimberly J President and CEO Dec 12, 2013 Sale $30.68 2,500 76,705 26,866 Dec 16, 2013, 02:34 PM
Schorno Dean L CFO Dec 09, 2013 Option Exercise $17.23 3,000 51,690 24,557 Dec 10, 2013, 04:40 PM
Schorno Dean L CFO Dec 09, 2013 Sale $33.25 3,000 99,761 23,557 Dec 10, 2013, 04:40 PM
LIVINGSTON RANDALL S Director Dec 02, 2013 Option Exercise $10.73 1,000 10,730 7,149 Dec 04, 2013, 05:52 PM
LIVINGSTON RANDALL S Director Dec 02, 2013 Sale $34.92 1,000 34,920 6,149 Dec 04, 2013, 05:52 PM
Popovits Kimberly J President and CEO Nov 13, 2013 Option Exercise $9.39 2,500 23,475 29,366 Nov 14, 2013, 05:59 PM
Popovits Kimberly J President and CEO Nov 12, 2013 Option Exercise $9.39 2,500 23,475 29,366 Nov 14, 2013, 05:59 PM
Popovits Kimberly J President and CEO Nov 13, 2013 Sale $35.00 2,500 87,500 26,866 Nov 14, 2013, 05:59 PM
Popovits Kimberly J President and CEO Nov 12, 2013 Sale $34.17 2,500 85,423 26,866 Nov 14, 2013, 05:59 PM
Schorno Dean L CFO Nov 08, 2013 Option Exercise $17.33 3,000 51,990 24,436 Nov 13, 2013, 07:45 PM
Schorno Dean L CFO Nov 08, 2013 Sale $33.36 3,000 100,090 21,436 Nov 13, 2013, 07:45 PM
Cole G Bradley COO Nov 06, 2013 Option Exercise $1.33 2,868 3,814 21,003 Nov 08, 2013, 08:37 PM
Cole G Bradley COO Nov 06, 2013 Sale $31.38 2,868 89,987 20,903 Nov 08, 2013, 08:37 PM
Shak Steven EVP of R&D & CMO Oct 15, 2013 Sale $29.67 5,000 148,341 308,283 Oct 17, 2013, 05:05 PM
Popovits Kimberly J President and CEO Oct 10, 2013 Option Exercise $4.79 2,500 11,978 29,366 Oct 15, 2013, 06:23 PM
Popovits Kimberly J President and CEO Oct 10, 2013 Sale $30.00 2,500 75,000 26,866 Oct 15, 2013, 06:23 PM
Cole G Bradley COO Oct 09, 2013 Option Exercise $1.33 2,500 3,325 20,635 Oct 11, 2013, 04:50 PM
Cole G Bradley COO Oct 09, 2013 Sale $29.95 2,500 74,885 18,135 Oct 11, 2013, 04:50 PM
MYERS WOODROW A JR Director Oct 01, 2013 Option Exercise $30.33 329 9,979 3,880 Oct 03, 2013, 08:12 PM
GRAHAM GINGER L Director Oct 01, 2013 Option Exercise $30.33 329 9,979 3,880 Oct 03, 2013, 08:11 PM
COLELLA SAMUEL D Director Oct 01, 2013 Option Exercise $30.33 329 9,979 3,880 Oct 03, 2013, 08:09 PM
Cohen Fred E Director Oct 01, 2013 Option Exercise $30.33 329 9,979 60,946 Oct 03, 2013, 08:07 PM
BAKER FELIX Director Oct 01, 2013 Option Exercise $30.33 3,948 119,743 11,242,918 Oct 02, 2013, 05:27 PM
Shak Steven EVP of R&D & CMO Sep 18, 2013 Sale $33.73 5,000 168,629 313,283 Sep 20, 2013, 05:38 PM
Popovits Kimberly J President and CEO Sep 12, 2013 Option Exercise $2.88 2,500 7,200 29,366 Sep 16, 2013, 05:05 PM
Popovits Kimberly J President and CEO Sep 12, 2013 Sale $34.31 2,500 85,787 26,866 Sep 16, 2013, 05:05 PM
Cole G Bradley COO Sep 09, 2013 Option Exercise $1.33 2,500 3,325 21,635 Sep 11, 2013, 04:05 PM
Cole G Bradley COO Sep 09, 2013 Sale $32.53 2,500 81,329 19,135 Sep 11, 2013, 04:05 PM
Schorno Dean L CFO Sep 06, 2013 Option Exercise $17.29 4,000 69,178 24,486 Sep 10, 2013, 08:20 PM
Schorno Dean L CFO Sep 06, 2013 Sale $32.90 4,000 131,600 21,436 Sep 10, 2013, 08:20 PM
LIVINGSTON RANDALL S Director Sep 03, 2013 Option Exercise $10.73 1,000 10,730 7,149 Sep 04, 2013, 05:51 PM
LIVINGSTON RANDALL S Director Sep 03, 2013 Sale $31.49 1,000 31,492 6,149 Sep 04, 2013, 05:51 PM
Shak Steven EVP of R&D & CMO Aug 14, 2013 Sale $32.98 5,000 164,905 318,283 Aug 16, 2013, 07:24 PM
Schorno Dean L CFO Aug 09, 2013 Option Exercise $17.18 4,000 68,720 25,436 Aug 15, 2013, 08:19 PM
Schorno Dean L CFO Aug 09, 2013 Sale $33.15 4,000 132,581 21,436 Aug 15, 2013, 08:19 PM
Schorno Dean L CFO Jul 09, 2013 Option Exercise $17.22 4,000 68,885 20,734 Aug 15, 2013, 08:17 PM
Schorno Dean L CFO Jul 09, 2013 Sale $33.81 4,000 135,237 17,836 Aug 15, 2013, 08:17 PM
Popovits Kimberly J President and CEO Aug 12, 2013 Option Exercise $2.88 2,500 7,200 29,366 Aug 14, 2013, 05:29 PM
Popovits Kimberly J President and CEO Aug 12, 2013 Sale $33.03 2,500 82,572 26,866 Aug 14, 2013, 05:29 PM
Schorno Dean L CFO Aug 09, 2013 Option Exercise $17.18 4,000 68,720 25,436 Aug 12, 2013, 08:48 PM
Schorno Dean L CFO Aug 09, 2013 Sale $33.15 4,000 132,581 21,436 Aug 12, 2013, 08:48 PM
Cole G Bradley COO Aug 07, 2013 Option Exercise $1.33 2,500 3,325 21,635 Aug 09, 2013, 05:16 PM
Cole G Bradley COO Aug 07, 2013 Sale $33.66 2,500 84,140 19,135 Aug 09, 2013, 05:16 PM
Shak Steven EVP of R&D & CMO Jul 23, 2013 Sale $35.33 5,000 176,670 318,283 Jul 26, 2013, 02:05 PM
Popovits Kimberly J President and CEO Jul 11, 2013 Option Exercise $2.88 2,900 8,352 20,766 Jul 15, 2013, 07:57 PM
Popovits Kimberly J President and CEO Jul 12, 2013 Option Exercise $2.88 2,100 6,048 19,966 Jul 15, 2013, 07:57 PM
Popovits Kimberly J President and CEO Jul 11, 2013 Sale $34.32 2,900 99,528 17,866 Jul 15, 2013, 07:57 PM
Popovits Kimberly J President and CEO Jul 12, 2013 Sale $35.00 2,100 73,500 17,866 Jul 15, 2013, 07:57 PM
Schorno Dean L CFO Jul 09, 2013 Option Exercise $17.33 4,000 69,320 21,836 Jul 10, 2013, 07:47 PM
Schorno Dean L CFO Jul 09, 2013 Sale $33.81 4,000 135,237 17,836 Jul 10, 2013, 07:47 PM
Cole G Bradley COO Jul 08, 2013 Option Exercise $1.33 2,500 3,325 15,635 Jul 10, 2013, 07:45 PM
Cole G Bradley COO Jul 08, 2013 Sale $33.33 2,500 83,327 13,135 Jul 10, 2013, 07:45 PM
BAKER FELIX Director Jul 01, 2013 Option Exercise $32.85 3,636 119,443 11,242,260 Jul 03, 2013, 05:25 PM
MYERS WOODROW A JR Director Jul 01, 2013 Option Exercise $32.85 303 9,954 3,551 Jul 03, 2013, 05:17 PM
GRAHAM GINGER L Director Jul 01, 2013 Option Exercise $32.85 303 9,954 3,551 Jul 03, 2013, 05:16 PM
COLELLA SAMUEL D Director Jul 01, 2013 Option Exercise $32.85 303 9,954 3,551 Jul 03, 2013, 05:15 PM
Cohen Fred E Director Jul 01, 2013 Option Exercise $32.85 303 9,954 60,617 Jul 03, 2013, 05:14 PM
Shak Steven EVP of R&D & CMO Jun 18, 2013 Sale $33.52 5,000 167,605 326,783 Jun 19, 2013, 05:32 PM
Popovits Kimberly J President and CEO Jun 12, 2013 Option Exercise $2.88 5,000 14,400 20,366 Jun 14, 2013, 04:39 PM
Popovits Kimberly J President and CEO Jun 12, 2013 Sale $35.68 5,000 178,399 17,866 Jun 14, 2013, 04:39 PM
Schorno Dean L CFO Jun 10, 2013 Option Exercise $17.33 4,000 69,320 21,836 Jun 12, 2013, 08:28 PM
Schorno Dean L CFO Jun 10, 2013 Sale $35.88 4,000 143,525 17,836 Jun 12, 2013, 08:28 PM
Cole G Bradley COO Jun 05, 2013 Option Exercise $1.33 2,500 3,325 15,635 Jun 07, 2013, 05:34 PM
Cole G Bradley COO Jun 05, 2013 Sale $36.47 2,500 91,172 13,135 Jun 07, 2013, 05:34 PM
BAKER FELIX Director Jun 04, 2013 Buy $36.62 163,659 5,993,192 11,051,768 Jun 05, 2013, 05:23 PM
BAKER FELIX Director Jun 05, 2013 Buy $35.81 194,621 6,970,351 11,241,654 Jun 05, 2013, 05:23 PM
BAKER FELIX Director Jun 05, 2013 Buy $35.81 23,152 829,189 1,730,777 Jun 05, 2013, 05:23 PM
LIVINGSTON RANDALL S Director Jun 03, 2013 Option Exercise $10.73 1,000 10,730 7,149 Jun 04, 2013, 07:03 PM
LIVINGSTON RANDALL S Director Jun 03, 2013 Sale $36.40 1,000 36,400 6,149 Jun 04, 2013, 07:03 PM
BAKER FELIX Director Jun 03, 2013 Buy $36.69 13,644 500,556 1,690,226 Jun 03, 2013, 05:40 PM
BAKER FELIX Director May 31, 2013 Buy $36.75 51,242 1,883,256 10,797,159 Jun 03, 2013, 05:40 PM
BAKER FELIX Director Jun 03, 2013 Buy $36.69 114,697 4,207,877 10,909,066 Jun 03, 2013, 05:40 PM
BAKER FELIX Director May 29, 2013 Buy $36.82 5,046 185,802 1,671,081 May 29, 2013, 06:06 PM
BAKER FELIX Director May 28, 2013 Buy $36.93 74,266 2,742,933 10,711,599 May 29, 2013, 06:06 PM
BAKER FELIX Director May 29, 2013 Buy $36.82 41,954 1,544,813 10,752,532 May 29, 2013, 06:06 PM
BAKER FELIX Director May 23, 2013 Buy $36.59 3,255 119,106 10,579,208 May 24, 2013, 05:04 PM
BAKER FELIX Director May 24, 2013 Buy $36.93 62,517 2,308,909 10,646,920 May 24, 2013, 05:04 PM
BAKER FELIX Director May 23, 2013 Buy $36.99 13,645 504,693 10,592,521 May 24, 2013, 05:04 PM
HIBBS KATHY L SVP & General Counsel May 22, 2013 Option Exercise $21.07 1,000 21,070 8,087 May 23, 2013, 05:24 PM
HIBBS KATHY L SVP & General Counsel May 22, 2013 Sale $37.48 1,000 37,480 7,087 May 23, 2013, 05:24 PM
Shak Steven EVP of R&D & CMO May 21, 2013 Sale $37.19 5,000 185,957 327,380 May 22, 2013, 07:54 PM
LIVINGSTON RANDALL S Director May 15, 2013 Option Exercise $1.33 1,337 1,774 7,486 May 17, 2013, 05:33 PM
LIVINGSTON RANDALL S Director May 15, 2013 Sale $35.83 1,337 47,904 6,149 May 17, 2013, 05:33 PM
BAKER FELIX Director May 15, 2013 Buy $36.41 52,133 1,898,361 10,561,048 May 16, 2013, 06:03 PM
BAKER FELIX Director May 16, 2013 Buy $36.54 17,186 627,963 10,577,816 May 16, 2013, 06:03 PM
BAKER FELIX Director May 16, 2013 Buy $36.54 2,120 77,463 1,649,473 May 16, 2013, 06:03 PM
HIBBS KATHY L SVP & General Counsel May 13, 2013 Option Exercise $21.07 1,250 26,337 8,337 May 15, 2013, 06:10 PM
HIBBS KATHY L SVP & General Counsel May 13, 2013 Sale $34.42 1,250 43,031 7,087 May 15, 2013, 06:10 PM
Popovits Kimberly J President and CEO May 13, 2013 Option Exercise $2.88 5,000 14,400 19,463 May 15, 2013, 06:08 PM
Popovits Kimberly J President and CEO May 13, 2013 Sale $34.70 5,000 173,506 16,963 May 15, 2013, 06:08 PM
BAKER FELIX Director May 14, 2013 Buy $35.53 27,184 965,899 10,515,769 May 14, 2013, 06:40 PM
BAKER FELIX Director May 13, 2013 Buy $34.02 144,478 4,914,910 10,492,159 May 14, 2013, 06:40 PM
BAKER FELIX Director May 13, 2013 Buy $34.56 68,764 2,376,256 10,351,197 May 14, 2013, 06:40 PM
Schorno Dean L CFO May 09, 2013 Option Exercise $17.18 4,000 68,720 21,092 May 13, 2013, 05:33 PM
Schorno Dean L CFO May 09, 2013 Sale $36.02 4,000 144,088 17,092 May 13, 2013, 05:33 PM
Cole G Bradley COO May 08, 2013 Option Exercise $1.33 2,500 3,325 15,040 May 09, 2013, 03:16 PM
Cole G Bradley COO May 08, 2013 Sale $35.99 2,500 89,964 12,540 May 09, 2013, 03:16 PM
Popovits Kimberly J President and CEO Apr 23, 2013 Option Exercise $2.88 2,500 7,200 19,463 Apr 25, 2013, 05:55 PM
Popovits Kimberly J President and CEO Apr 23, 2013 Sale $30.00 2,500 75,000 16,963 Apr 25, 2013, 05:55 PM
Cole G Bradley COO Apr 03, 2013 Option Exercise $1.33 2,500 3,325 15,040 Apr 05, 2013, 05:50 PM
Cole G Bradley COO Apr 03, 2013 Sale $27.79 2,500 69,483 12,540 Apr 05, 2013, 05:50 PM
BAKER FELIX Director Apr 01, 2013 Option Exercise $27.99 4,284 119,909 10,306,953 Apr 03, 2013, 05:50 PM
GRAHAM GINGER L Director Apr 01, 2013 Option Exercise $27.99 357 9,992 3,248 Apr 03, 2013, 04:56 PM
Cohen Fred E Director Apr 01, 2013 Option Exercise $27.99 357 9,992 60,314 Apr 03, 2013, 04:55 PM
COLELLA SAMUEL D Director Apr 01, 2013 Option Exercise $27.99 357 9,992 3,248 Apr 03, 2013, 04:54 PM
MYERS WOODROW A JR Director Apr 01, 2013 Option Exercise $27.99 357 9,992 3,248 Apr 03, 2013, 04:53 PM
Cole G Bradley COO Mar 06, 2013 Option Exercise $1.33 2,500 3,325 15,040 Mar 08, 2013, 04:14 PM
Cole G Bradley COO Mar 06, 2013 Sale $28.57 2,500 71,435 12,540 Mar 08, 2013, 04:14 PM
HIBBS KATHY L SVP & General Counsel Feb 20, 2013 Sale $28.13 2,716 76,399 7,087 Feb 22, 2013, 07:50 PM
BAKER FELIX Director Feb 21, 2013 Buy $27.64 25,120 694,237 10,306,239 Feb 21, 2013, 06:11 PM
BAKER FELIX Director Feb 21, 2013 Buy $27.64 3,080 85,122 1,614,513 Feb 21, 2013, 06:11 PM
BAKER FELIX Director Feb 20, 2013 Buy $27.97 20,885 584,220 10,281,731 Feb 21, 2013, 06:11 PM
Popovits Kimberly J President and CEO Feb 15, 2013 Option Exercise $28.77 2,560 73,651 18,207 Feb 20, 2013, 07:45 PM
Cole G Bradley COO Feb 15, 2013 Option Exercise $28.77 1,819 52,333 13,239 Feb 20, 2013, 07:33 PM
Shak Steven EVP of R&D & CMO Feb 15, 2013 Option Exercise $28.77 1,388 39,933 333,211 Feb 20, 2013, 07:27 PM
Schorno Dean L CFO Feb 15, 2013 Option Exercise $28.77 1,141 32,827 16,799 Feb 20, 2013, 07:22 PM
HIBBS KATHY L SVP & General Counsel Feb 15, 2013 Option Exercise $28.77 1,850 53,225 10,495 Feb 20, 2013, 07:19 PM
MYERS WOODROW A JR Director Feb 14, 2013 Option Exercise $18.88 41,250 778,635 44,141 Feb 15, 2013, 07:32 PM
MYERS WOODROW A JR Director Feb 14, 2013 Sale $28.40 41,250 1,171,529 2,891 Feb 15, 2013, 07:32 PM
BAKER FELIX Director Feb 13, 2013 Buy $28.58 17,200 491,585 10,233,478 Feb 14, 2013, 05:51 PM
BAKER FELIX Director Feb 14, 2013 Buy $28.43 30,860 877,384 10,263,580 Feb 14, 2013, 05:51 PM
BAKER FELIX Director Feb 14, 2013 Buy $28.43 3,940 112,019 1,609,152 Feb 14, 2013, 05:51 PM
BAKER FELIX Director Feb 11, 2013 Buy $28.23 70,929 2,002,446 10,218,600 Feb 11, 2013, 06:43 PM
BAKER FELIX Director Feb 11, 2013 Buy $28.23 9,055 255,638 1,603,265 Feb 11, 2013, 06:43 PM
BAKER FELIX Director Feb 08, 2013 Buy $27.96 36,376 1,017,106 10,149,413 Feb 11, 2013, 06:43 PM
Cole G Bradley COO Feb 06, 2013 Option Exercise $1.33 2,500 3,325 16,585 Feb 07, 2013, 05:02 PM
Cole G Bradley COO Feb 06, 2013 Sale $28.03 2,500 70,076 14,085 Feb 07, 2013, 05:02 PM
LIVINGSTON RANDALL S Director Jan 28, 2013 Option Exercise $1.33 2,000 2,653 8,149 Jan 29, 2013, 05:22 PM
LIVINGSTON RANDALL S Director Jan 28, 2013 Sale $28.77 2,000 57,543 6,149 Jan 29, 2013, 05:22 PM
Schorno Dean L CFO Jan 09, 2013 Option Exercise $9.39 2,625 24,649 19,980 Jan 11, 2013, 07:31 PM
Schorno Dean L CFO Jan 09, 2013 Sale $28.00 2,625 73,500 17,355 Jan 11, 2013, 07:31 PM
Cole G Bradley COO Jan 09, 2013 Option Exercise $1.33 2,500 3,325 16,585 Jan 11, 2013, 07:29 PM
Cole G Bradley COO Jan 09, 2013 Sale $27.88 2,500 69,694 14,085 Jan 11, 2013, 07:29 PM
BAKER FELIX Director Jan 01, 2013 Option Exercise $27.24 2,202 59,982 10,117,829 Jan 03, 2013, 08:14 PM
MYERS WOODROW A JR Director Jan 01, 2013 Option Exercise $27.24 367 9,997 2,891 Jan 03, 2013, 05:10 PM
GRAHAM GINGER L Director Jan 01, 2013 Option Exercise $27.24 367 9,997 2,891 Jan 03, 2013, 05:09 PM
COLELLA SAMUEL D Director Jan 01, 2013 Option Exercise $27.24 367 9,997 2,891 Jan 03, 2013, 05:08 PM
Cohen Fred E Director Jan 01, 2013 Option Exercise $27.24 367 9,997 59,957 Jan 03, 2013, 05:06 PM
Shak Steven EVP of R&D & CMO Dec 18, 2012 Sale $27.74 5,000 138,721 333,768 Dec 19, 2012, 07:02 PM
Popovits Kimberly J President and CEO Dec 13, 2012 Sale $27.79 5,000 138,955 208,806 Dec 14, 2012, 05:26 PM
Schorno Dean L CFO Dec 11, 2012 Option Exercise $9.39 3,000 28,170 20,355 Dec 12, 2012, 05:37 PM
Schorno Dean L CFO Dec 11, 2012 Sale $28.00 3,000 84,000 17,355 Dec 12, 2012, 05:37 PM
Cole G Bradley COO Dec 06, 2012 Option Exercise $1.33 2,500 3,325 16,585 Dec 07, 2012, 06:50 PM
Cole G Bradley COO Dec 06, 2012 Sale $27.18 2,500 67,947 14,085 Dec 07, 2012, 06:50 PM
LIVINGSTON RANDALL S Director Nov 26, 2012 Option Exercise $1.33 2,000 2,653 8,149 Nov 27, 2012, 05:05 PM
LIVINGSTON RANDALL S Director Nov 26, 2012 Sale $27.84 2,000 55,683 6,149 Nov 27, 2012, 05:05 PM
BAKER FELIX Director Nov 21, 2012 Buy $27.54 300 8,262 10,117,174 Nov 23, 2012, 01:24 PM
BAKER FELIX Director Nov 20, 2012 Buy $26.83 229,000 6,143,360 10,116,906 Nov 23, 2012, 01:24 PM
Shak Steven EVP of R&D & CMO Nov 20, 2012 Sale $26.94 5,000 134,710 339,067 Nov 21, 2012, 05:36 PM
COLELLA SAMUEL D Director Nov 20, 2012 Sale $26.52 1,871 49,614 0 Nov 20, 2012, 07:51 PM
COLELLA SAMUEL D Director Nov 19, 2012 Sale $26.97 16,573 447,043 3,629 Nov 20, 2012, 07:51 PM
COLELLA SAMUEL D Director Nov 19, 2012 Sale $26.97 8,543 230,441 1,871 Nov 20, 2012, 07:51 PM
COLELLA SAMUEL D Director Nov 20, 2012 Sale $26.52 3,629 96,232 0 Nov 20, 2012, 07:51 PM
Popovits Kimberly J President and CEO Nov 14, 2012 Sale $27.24 5,000 136,217 213,406 Nov 16, 2012, 06:20 PM
BAKER FELIX Director Nov 14, 2012 Buy $27.32 103,167 2,818,161 9,914,595 Nov 14, 2012, 09:16 PM
BAKER FELIX Director Nov 13, 2012 Buy $27.99 103,839 2,906,651 9,822,003 Nov 14, 2012, 09:05 PM
BAKER FELIX Director Nov 12, 2012 Buy $27.94 200,000 5,587,480 9,729,086 Nov 14, 2012, 09:05 PM
BAKER FELIX Director Nov 09, 2012 Buy $27.72 519,933 14,414,195 9,550,108 Nov 14, 2012, 09:05 PM
Schorno Dean L CFO Nov 12, 2012 Option Exercise $9.39 2,800 26,292 20,155 Nov 14, 2012, 03:38 PM
Schorno Dean L CFO Nov 09, 2012 Option Exercise $9.39 200 1,878 17,555 Nov 14, 2012, 03:38 PM
Schorno Dean L CFO Nov 12, 2012 Sale $28.00 2,800 78,400 17,355 Nov 14, 2012, 03:38 PM
Schorno Dean L CFO Nov 09, 2012 Sale $28.00 200 5,600 17,355 Nov 14, 2012, 03:38 PM
Cole G Bradley COO Nov 08, 2012 Option Exercise $1.33 2,500 3,325 16,585 Nov 13, 2012, 06:43 PM
Cole G Bradley COO Nov 08, 2012 Sale $28.62 2,500 71,542 14,085 Nov 13, 2012, 06:43 PM
Shak Steven EVP of R&D & CMO Oct 16, 2012 Sale $35.25 5,000 176,254 348,434 Oct 18, 2012, 06:38 PM
Popovits Kimberly J President and CEO Oct 16, 2012 Option Exercise $23.31 5,000 116,550 24,523 Oct 17, 2012, 05:59 PM
Popovits Kimberly J President and CEO Oct 15, 2012 Sale $31.17 5,000 155,838 218,406 Oct 17, 2012, 05:59 PM
Popovits Kimberly J President and CEO Oct 16, 2012 Sale $35.00 5,000 175,000 19,523 Oct 17, 2012, 05:59 PM
Schorno Dean L CFO Oct 12, 2012 Option Exercise $9.39 3,000 28,170 20,355 Oct 16, 2012, 05:44 PM
Schorno Dean L CFO Oct 12, 2012 Sale $33.79 3,000 101,358 17,355 Oct 16, 2012, 05:44 PM
HIBBS KATHY L SVP & General Counsel Oct 11, 2012 Option Exercise $21.07 1,250 26,337 12,617 Oct 15, 2012, 05:48 PM
HIBBS KATHY L SVP & General Counsel Oct 11, 2012 Sale $33.78 1,250 42,224 11,367 Oct 15, 2012, 05:48 PM
Cole G Bradley COO Oct 09, 2012 Option Exercise $1.33 2,500 3,325 16,585 Oct 11, 2012, 05:51 PM
Cole G Bradley COO Oct 09, 2012 Sale $34.80 2,500 86,990 14,085 Oct 11, 2012, 05:51 PM
MYERS WOODROW A JR Director Oct 01, 2012 Option Exercise $35.89 288 10,336 2,524 Oct 03, 2012, 06:58 PM
GRAHAM GINGER L Director Oct 01, 2012 Option Exercise $35.89 288 10,336 2,524 Oct 03, 2012, 06:47 PM
Cohen Fred E Director Oct 01, 2012 Option Exercise $35.89 288 10,336 59,590 Oct 03, 2012, 06:44 PM
COLELLA SAMUEL D Director Oct 01, 2012 Option Exercise $35.89 288 10,336 2,524 Oct 03, 2012, 06:43 PM
BAKER FELIX Director Oct 01, 2012 Option Exercise $35.89 288 10,336 288 Oct 03, 2012, 05:59 PM
Shak Steven EVP of R&D & CMO Sep 18, 2012 Sale $33.76 5,000 168,800 348,768 Sep 19, 2012, 05:44 PM
Popovits Kimberly J President and CEO Sep 13, 2012 Sale $31.69 5,000 158,450 223,406 Sep 17, 2012, 07:32 PM
Cole G Bradley COO Sep 06, 2012 Option Exercise $1.33 2,500 3,325 16,585 Sep 10, 2012, 05:43 PM
Cole G Bradley COO Sep 06, 2012 Sale $35.01 2,500 87,514 14,085 Sep 10, 2012, 05:43 PM
Cohen Fred E Director Aug 01, 2012 Option Exercise $10.73 8,250 88,522 59,302 Aug 31, 2012, 05:38 PM
MYERS WOODROW A JR Director Aug 20, 2012 Option Exercise $9.95 5,507 54,795 7,743 Aug 22, 2012, 06:31 PM
MYERS WOODROW A JR Director Aug 21, 2012 Option Exercise $9.95 10,993 109,380 13,229 Aug 22, 2012, 06:31 PM
MYERS WOODROW A JR Director Aug 21, 2012 Sale $35.28 10,993 387,803 2,236 Aug 22, 2012, 06:31 PM
MYERS WOODROW A JR Director Aug 20, 2012 Sale $35.06 5,507 193,061 2,236 Aug 22, 2012, 06:31 PM
Shak Steven EVP of R&D & CMO Aug 20, 2012 Sale $34.99 5,000 174,939 353,768 Aug 22, 2012, 06:29 PM
Popovits Kimberly J President and CEO Aug 14, 2012 Option Exercise $23.31 3,103 72,331 22,626 Aug 15, 2012, 03:12 PM
Popovits Kimberly J President and CEO Aug 13, 2012 Option Exercise $23.31 1,897 44,219 21,420 Aug 15, 2012, 03:12 PM
Popovits Kimberly J President and CEO Aug 13, 2012 Sale $35.01 1,897 66,412 19,523 Aug 15, 2012, 03:12 PM
Popovits Kimberly J President and CEO Aug 13, 2012 Sale $34.39 5,000 171,936 228,406 Aug 15, 2012, 03:12 PM
Popovits Kimberly J President and CEO Aug 14, 2012 Sale $35.07 3,103 108,814 19,523 Aug 15, 2012, 03:12 PM
Cole G Bradley COO Aug 08, 2012 Option Exercise $1.33 2,500 3,325 16,585 Aug 09, 2012, 04:38 PM
Cole G Bradley COO Aug 08, 2012 Sale $30.49 2,500 76,236 14,085 Aug 09, 2012, 04:38 PM
LIVINGSTON RANDALL S Director Jul 26, 2012 Option Exercise $1.33 2,000 2,653 8,149 Jul 27, 2012, 05:51 PM
LIVINGSTON RANDALL S Director Jul 26, 2012 Sale $35.90 2,000 71,800 6,149 Jul 27, 2012, 05:51 PM
Shak Steven Chief Medical Officer Jul 24, 2012 Sale $34.24 5,000 171,196 358,768 Jul 25, 2012, 11:10 AM
Popovits Kimberly J President and CEO Jul 13, 2012 Option Exercise $23.31 2,100 48,951 21,623 Jul 17, 2012, 05:57 PM
Popovits Kimberly J President and CEO Jul 13, 2012 Sale $35.03 2,100 73,570 19,523 Jul 17, 2012, 05:57 PM
Popovits Kimberly J President and CEO Jul 13, 2012 Sale $34.64 5,000 173,207 233,406 Jul 17, 2012, 05:57 PM
Scott Randal W CEO, InVitae Corporation* Jul 10, 2012 Sale $35.97 15,000 539,537 1,200,317 Jul 12, 2012, 02:42 PM
Scott Randal W CEO, InVitae Corporation* Jul 11, 2012 Sale $34.81 15,000 522,134 1,185,417 Jul 12, 2012, 02:42 PM
Cole G Bradley COO Jul 05, 2012 Option Exercise $1.33 2,500 3,325 16,585 Jul 06, 2012, 02:16 PM
Cole G Bradley COO Jul 05, 2012 Sale $35.95 2,500 89,864 14,085 Jul 06, 2012, 02:16 PM
COLELLA SAMUEL D Director Jul 01, 2012 Option Exercise $33.40 299 9,987 2,236 Jul 03, 2012, 07:27 PM
Cohen Fred E Director Jul 01, 2012 Option Exercise $33.40 299 9,987 51,052 Jul 03, 2012, 07:23 PM
GRAHAM GINGER L Director Jul 01, 2012 Option Exercise $33.40 299 9,987 2,236 Jul 03, 2012, 07:21 PM
MYERS WOODROW A JR Director Jul 01, 2012 Option Exercise $33.40 299 9,987 2,236 Jul 03, 2012, 07:01 PM
Shak Steven Chief Medical Officer Jun 25, 2012 Sale $33.25 5,000 166,252 363,768 Jun 27, 2012, 07:05 PM
Popovits Kimberly J President and CEO Jun 13, 2012 Sale $33.36 5,000 166,805 238,406 Jun 19, 2012, 07:50 PM
Popovits Kimberly J President and CEO May 31, 2012 Buy $23.11 919 21,239 19,523 Jun 15, 2012, 05:27 PM
Popovits Kimberly J President and CEO Jun 13, 2012 Sale $33.36 5,000 166,805 238,406 Jun 15, 2012, 05:27 PM
Scott Randal W CEO, InVitae Corporation* Jun 12, 2012 Sale $33.31 15,000 499,654 1,215,117 Jun 13, 2012, 02:46 PM
Scott Randal W CEO, InVitae Corporation* Jun 11, 2012 Sale $33.77 15,000 506,562 1,230,717 Jun 13, 2012, 02:46 PM
Cole G Bradley COO Jun 06, 2012 Option Exercise $1.33 2,500 3,325 16,007 Jun 08, 2012, 02:39 PM
Cole G Bradley COO Jun 06, 2012 Sale $33.97 2,500 84,919 13,507 Jun 08, 2012, 02:39 PM
Shak Steven Chief Medical Officer May 24, 2012 Sale $33.80 5,000 168,979 367,849 May 29, 2012, 05:44 PM
BAKER JULIAN Director May 22, 2012 Buy $32.94 17,406 573,401 9,086,690 May 23, 2012, 05:03 PM
BAKER JULIAN Director May 21, 2012 Buy $32.18 150,000 4,826,972 9,069,664 May 23, 2012, 05:03 PM
COLELLA SAMUEL D Director May 18, 2012 Sale $32.13 6,137 197,168 20,202 May 18, 2012, 06:21 PM
COLELLA SAMUEL D Director May 18, 2012 Sale $32.13 3,163 101,620 10,414 May 18, 2012, 06:21 PM
COLELLA SAMUEL D Director May 17, 2012 Sale $33.52 11,213 375,888 26,339 May 18, 2012, 06:21 PM
COLELLA SAMUEL D Director May 17, 2012 Sale $33.52 5,781 193,794 13,577 May 18, 2012, 06:21 PM
Popovits Kimberly J President and CEO May 16, 2012 Option Exercise $23.31 5,000 116,550 250,656 May 17, 2012, 05:39 PM
Popovits Kimberly J President and CEO May 16, 2012 Sale $35.00 5,000 175,000 245,656 May 17, 2012, 05:39 PM
Popovits Kimberly J President and CEO May 15, 2012 Sale $33.46 5,000 167,292 245,656 May 17, 2012, 05:39 PM
Schorno Dean L CFO May 15, 2012 Sale $33.69 1,000 33,686 17,355 May 17, 2012, 05:35 PM
BAKER JULIAN Director May 16, 2012 Buy $34.46 23,621 813,925 8,922,942 May 16, 2012, 08:18 PM
BAKER JULIAN Director May 15, 2012 Buy $34.09 140,000 4,772,474 8,899,838 May 16, 2012, 08:18 PM
BAKER JULIAN Director May 14, 2012 Buy $33.68 212,438 7,153,896 8,762,905 May 16, 2012, 08:18 PM
Scott Randal W CEO, InVitae Corporation* May 10, 2012 Sale $29.93 15,000 448,981 1,260,517 May 14, 2012, 05:39 PM
Scott Randal W CEO, InVitae Corporation* May 11, 2012 Sale $30.52 15,000 457,742 1,252,917 May 14, 2012, 05:39 PM
BAKER JULIAN Director May 11, 2012 Buy $30.22 26,660 805,567 8,555,121 May 11, 2012, 06:01 PM
BAKER JULIAN Director May 10, 2012 Buy $29.87 68,681 2,051,783 8,529,088 May 11, 2012, 06:01 PM
BAKER JULIAN Director May 09, 2012 Buy $29.90 19,547 584,367 8,462,023 May 11, 2012, 06:01 PM
Cole G Bradley COO May 09, 2012 Option Exercise $1.33 2,500 3,325 16,007 May 11, 2012, 12:53 PM
Cole G Bradley COO May 09, 2012 Sale $28.87 2,500 72,174 13,507 May 11, 2012, 12:53 PM
BAKER JULIAN Director May 04, 2012 Buy $28.02 53,128 1,488,643 8,305,414 May 08, 2012, 07:00 PM
BAKER JULIAN Director May 08, 2012 Buy $28.83 86,033 2,480,619 8,442,936 May 08, 2012, 07:00 PM
BAKER JULIAN Director May 07, 2012 Buy $28.26 56,540 1,597,965 8,358,928 May 08, 2012, 07:00 PM
LIVINGSTON RANDALL S Director Apr 26, 2012 Option Exercise $1.33 2,000 2,653 8,149 Apr 27, 2012, 04:30 PM
LIVINGSTON RANDALL S Director Apr 26, 2012 Sale $28.21 2,000 56,429 6,149 Apr 27, 2012, 04:30 PM
Shak Steven Chief Medical Officer Apr 24, 2012 Sale $27.93 5,000 139,630 372,849 Apr 26, 2012, 09:49 AM
Popovits Kimberly J President and CEO Apr 23, 2012 Sale $27.79 5,000 138,964 250,656 Apr 24, 2012, 05:06 PM
Schorno Dean L CFO Apr 16, 2012 Sale $27.98 1,000 27,980 18,355 Apr 17, 2012, 04:12 PM
Scott Randal W CEO, InVitae Corporation* Apr 11, 2012 Sale $28.38 10,000 283,790 1,275,117 Apr 12, 2012, 05:36 PM
Scott Randal W CEO, InVitae Corporation* Apr 10, 2012 Sale $28.81 10,000 288,081 1,285,948 Apr 12, 2012, 05:36 PM
Cole G Bradley COO Apr 04, 2012 Option Exercise $1.33 2,500 3,325 16,007 Apr 06, 2012, 01:06 PM
Cole G Bradley COO Apr 04, 2012 Sale $30.28 2,500 75,691 13,507 Apr 06, 2012, 01:06 PM
MYERS WOODROW A JR Director Apr 01, 2012 Option Exercise $30.61 326 9,979 1,937 Apr 03, 2012, 02:17 PM
GRAHAM GINGER L Director Apr 01, 2012 Option Exercise $30.61 326 9,979 1,937 Apr 03, 2012, 02:16 PM
COLELLA SAMUEL D Director Apr 01, 2012 Option Exercise $30.61 326 9,979 1,937 Apr 03, 2012, 02:14 PM
Cohen Fred E Director Apr 01, 2012 Option Exercise $30.61 326 9,979 50,753 Apr 03, 2012, 02:13 PM
Popovits Kimberly J President and CEO Mar 22, 2012 Sale $30.07 5,000 150,337 255,656 Mar 26, 2012, 09:09 AM
Shak Steven Chief Medical Officer Mar 22, 2012 Sale $30.08 5,000 150,415 377,849 Mar 26, 2012, 09:08 AM
Shak Steven Chief Medical Officer Mar 22, 2012 Sale $30.08 5,000 150,415 377,849 Mar 23, 2012, 06:45 PM
Popovits Kimberly J President and CEO Mar 22, 2012 Sale $30.07 5,000 150,337 255,656 Mar 23, 2012, 06:41 PM
Schorno Dean L CFO Mar 15, 2012 Sale $31.08 1,000 31,080 19,355 Mar 19, 2012, 09:08 AM
Scott Randal W CEO, InVitae Corporation Mar 12, 2012 Sale $30.98 15,000 464,681 1,310,117 Mar 14, 2012, 01:21 PM
Scott Randal W CEO, InVitae Corporation Mar 13, 2012 Sale $31.12 15,000 466,764 1,295,117 Mar 14, 2012, 01:21 PM
Baker Biotech Capital (GP), LLC Director Mar 08, 2012 Buy $30.36 2,162 65,647 1,484,977 Mar 09, 2012, 06:28 PM
Baker Biotech Capital (GP), LLC Director Mar 07, 2012 Buy $29.88 2,346 70,097 1,482,815 Mar 09, 2012, 06:28 PM
14159 capital (GP), LLC Director Mar 07, 2012 Buy $29.88 583 17,420 227,324 Mar 09, 2012, 06:28 PM
14159 capital (GP), LLC Director Mar 08, 2012 Buy $30.36 516 15,668 227,840 Mar 09, 2012, 06:28 PM
Baker Brothers Life Sciences Capital (GP), LLC Director Mar 08, 2012 Buy $30.36 19,513 592,489 8,255,421 Mar 09, 2012, 06:27 PM
Baker Brothers Life Sciences Capital (GP), LLC Director Mar 07, 2012 Buy $29.88 22,071 659,464 8,235,908 Mar 09, 2012, 06:27 PM
Cole G Bradley COO Mar 08, 2012 Option Exercise $1.33 2,500 3,325 16,007 Mar 09, 2012, 05:28 PM
Cole G Bradley COO Mar 08, 2012 Sale $29.94 2,500 74,850 13,507 Mar 09, 2012, 05:28 PM
Baker Brothers Life Sciences Capital (GP), LLC Director Mar 05, 2012 Buy $30.01 155,014 4,651,479 8,213,837 Mar 05, 2012, 06:28 PM
Baker Brothers Life Sciences Capital (GP), LLC Director Mar 02, 2012 Buy $29.52 91,459 2,699,915 8,058,823 Mar 05, 2012, 06:28 PM
Baker Brothers Life Sciences Capital (GP), LLC Director Mar 01, 2012 Buy $29.47 15,288 450,543 7,967,364 Mar 05, 2012, 06:28 PM
14159 capital (GP), LLC Director Mar 01, 2012 Buy $29.47 405 11,936 220,223 Mar 05, 2012, 06:27 PM
14159 capital (GP), LLC Director Mar 05, 2012 Buy $30.01 4,099 122,998 226,741 Mar 05, 2012, 06:27 PM
14159 capital (GP), LLC Director Mar 02, 2012 Buy $29.52 2,419 71,410 222,642 Mar 05, 2012, 06:27 PM
Baker Biotech Capital (GP), LLC Director Mar 05, 2012 Buy $30.01 18,597 558,037 1,480,469 Mar 05, 2012, 06:26 PM
Baker Biotech Capital (GP), LLC Director Mar 02, 2012 Buy $29.52 10,972 323,899 1,461,872 Mar 05, 2012, 06:26 PM
Baker Biotech Capital (GP), LLC Director Mar 01, 2012 Buy $29.47 1,763 51,956 1,450,900 Mar 05, 2012, 06:26 PM
14159 capital (GP), LLC Director Feb 28, 2012 Buy $29.11 1,353 39,384 215,669 Feb 29, 2012, 05:42 PM
14159 capital (GP), LLC Director Feb 27, 2012 Buy $29.03 974 28,276 214,316 Feb 29, 2012, 05:42 PM
14159 capital (GP), LLC Director Feb 29, 2012 Buy $29.06 4,149 120,562 219,818 Feb 29, 2012, 05:42 PM
Baker Brothers Life Sciences Capital (GP), LLC Director Feb 27, 2012 Buy $29.03 36,881 1,070,678 7,743,926 Feb 29, 2012, 05:41 PM
Baker Brothers Life Sciences Capital (GP), LLC Director Feb 29, 2012 Buy $29.06 156,902 4,559,274 7,952,076 Feb 29, 2012, 05:41 PM
Baker Brothers Life Sciences Capital (GP), LLC Director Feb 28, 2012 Buy $29.11 51,248 1,491,752 7,795,174 Feb 29, 2012, 05:41 PM
Baker Biotech Capital (GP), LLC Director Feb 29, 2012 Buy $29.06 19,552 568,144 1,449,137 Feb 29, 2012, 05:39 PM
Baker Biotech Capital (GP), LLC Director Feb 28, 2012 Buy $29.11 5,934 172,730 1,429,585 Feb 29, 2012, 05:39 PM
Baker Biotech Capital (GP), LLC Director Feb 27, 2012 Buy $29.03 4,270 123,961 1,423,651 Feb 29, 2012, 05:39 PM
Popovits Kimberly J President and CEO Feb 24, 2012 Sale $28.85 5,000 144,255 260,656 Feb 27, 2012, 04:34 PM
Popovits Kimberly J