Insider Transactions for CADENCE PHARMACEUTICALS INC (CADX)

Owner Relationship Date Transaction Cost # Shares Value($) Total Shares Form 4
Kamdar Kim P. 10% Owner Mar 19, 2014 Option Exercise $14.00 27,500 385,000 0 Mar 21, 2014, 07:46 PM
TREU JESSE I 10% Owner Mar 19, 2014 Option Exercise $14.00 78,369 1,097,166 0 Mar 21, 2014, 07:43 PM
TREU JESSE I 10% Owner Mar 19, 2014 Option Exercise $14.00 7,313,241 102,385,374 0 Mar 21, 2014, 07:43 PM
TREU JESSE I 10% Owner Mar 19, 2014 Option Exercise $14.00 50,743 710,402 0 Mar 21, 2014, 07:43 PM
TREU JESSE I 10% Owner Mar 19, 2014 Option Exercise $14.00 2,972,678 41,617,492 0 Mar 21, 2014, 07:43 PM
TREU JESSE I 10% Owner Mar 19, 2014 Option Exercise $14.00 27,500 385,000 0 Mar 21, 2014, 07:43 PM
Halak Brian K 10% Owner Mar 19, 2014 Option Exercise $14.00 27,500 385,000 0 Mar 21, 2014, 07:39 PM
Halak Brian K 10% Owner Mar 19, 2014 Option Exercise $14.00 50,743 710,402 0 Mar 21, 2014, 07:39 PM
Halak Brian K 10% Owner Mar 19, 2014 Option Exercise $14.00 2,972,678 41,617,492 0 Mar 21, 2014, 07:39 PM
DOMAIN ASSOCIATES 10% Owner Mar 19, 2014 Option Exercise $14.00 27,500 385,000 0 Mar 21, 2014, 07:32 PM
Domain Partners VI, L.P. 10% Owner Mar 19, 2014 Option Exercise $14.00 7,313,241 102,385,374 0 Mar 21, 2014, 07:24 PM
VITULLO NICOLE 10% Owner Mar 19, 2014 Option Exercise $14.00 50,743 710,402 0 Mar 21, 2014, 07:21 PM
VITULLO NICOLE 10% Owner Mar 19, 2014 Option Exercise $14.00 2,972,678 41,617,492 0 Mar 21, 2014, 07:21 PM
VITULLO NICOLE 10% Owner Mar 19, 2014 Option Exercise $14.00 27,500 385,000 0 Mar 21, 2014, 07:21 PM
VITULLO NICOLE 10% Owner Mar 19, 2014 Option Exercise $14.00 78,369 1,097,166 0 Mar 21, 2014, 07:21 PM
VITULLO NICOLE 10% Owner Mar 19, 2014 Option Exercise $14.00 7,313,241 102,385,374 0 Mar 21, 2014, 07:21 PM
DP VI Associates, L.P. 10% Owner Mar 19, 2014 Option Exercise $14.00 78,369 1,097,166 0 Mar 21, 2014, 07:02 PM
BLAIR JAMES C Director Mar 19, 2014 Option Exercise $14.00 78,369 1,097,166 0 Mar 21, 2014, 06:59 PM
BLAIR JAMES C Director Mar 19, 2014 Option Exercise $14.00 7,313,241 102,385,374 0 Mar 21, 2014, 06:59 PM
BLAIR JAMES C Director Mar 19, 2014 Option Exercise $14.00 50,743 710,402 0 Mar 21, 2014, 06:59 PM
BLAIR JAMES C Director Mar 19, 2014 Option Exercise $14.00 2,972,678 41,617,492 0 Mar 21, 2014, 06:59 PM
BLAIR JAMES C Director Mar 19, 2014 Option Exercise $14.00 27,500 385,000 0 Mar 21, 2014, 06:59 PM
DOVEY BRIAN H 10% Owner Mar 19, 2014 Option Exercise $14.00 2,972,678 41,617,492 0 Mar 21, 2014, 06:55 PM
DOVEY BRIAN H 10% Owner Mar 19, 2014 Option Exercise $14.00 27,500 385,000 0 Mar 21, 2014, 06:55 PM
DOVEY BRIAN H 10% Owner Mar 19, 2014 Option Exercise $14.00 78,369 1,097,166 0 Mar 21, 2014, 06:55 PM
DOVEY BRIAN H 10% Owner Mar 19, 2014 Option Exercise $14.00 7,313,241 102,385,374 0 Mar 21, 2014, 06:55 PM
DOVEY BRIAN H 10% Owner Mar 19, 2014 Option Exercise $14.00 50,743 710,402 0 Mar 21, 2014, 06:55 PM
SCHOEMAKER KATHLEEN K 10% Owner Mar 19, 2014 Option Exercise $14.00 50,743 710,402 0 Mar 21, 2014, 06:44 PM
SCHOEMAKER KATHLEEN K 10% Owner Mar 19, 2014 Option Exercise $14.00 2,972,678 41,617,492 0 Mar 21, 2014, 06:44 PM
SCHOEMAKER KATHLEEN K 10% Owner Mar 19, 2014 Option Exercise $14.00 27,500 385,000 0 Mar 21, 2014, 06:44 PM
SCHOEMAKER KATHLEEN K 10% Owner Mar 19, 2014 Option Exercise $14.00 78,369 1,097,166 0 Mar 21, 2014, 06:44 PM
SCHOEMAKER KATHLEEN K 10% Owner Mar 19, 2014 Option Exercise $14.00 7,313,241 102,385,374 0 Mar 21, 2014, 06:44 PM
DOMAIN PARTERS VII L P 10% Owner Mar 19, 2014 Option Exercise $14.00 2,972,678 41,617,492 0 Mar 21, 2014, 06:41 PM
DP VII ASSOCIATES LP 10% Owner Mar 19, 2014 Option Exercise $14.00 50,743 710,402 0 Mar 21, 2014, 06:27 PM
TWOMEY CHRISTOPHER J Director Mar 19, 2014 Option Exercise $14.00 35,000 490,000 0 Mar 21, 2014, 01:49 PM
TWOMEY CHRISTOPHER J Director Mar 19, 2014 Option Exercise $14.00 25,000 350,000 0 Mar 21, 2014, 01:49 PM
Rich Todd W Director Mar 19, 2014 Option Exercise $14.00 10,000 140,000 0 Mar 21, 2014, 01:47 PM
GARNER CAM L Director Mar 19, 2014 Option Exercise $14.00 486,595 6,812,330 0 Mar 21, 2014, 01:44 PM
GARNER CAM L Director Mar 19, 2014 Option Exercise $14.00 540,888 7,572,432 0 Mar 21, 2014, 01:44 PM
FRAZIER ALAN D Director Mar 19, 2014 Option Exercise $14.00 4,796,711 67,153,954 0 Mar 21, 2014, 01:43 PM
FRAZIER ALAN D Director Mar 19, 2014 Option Exercise $14.00 3,816,474 53,430,636 0 Mar 21, 2014, 01:43 PM
BARKER SAM L Director Mar 19, 2014 Option Exercise $14.00 20,000 280,000 0 Mar 21, 2014, 01:34 PM
ATWOOD BRIAN G Director Mar 19, 2014 Option Exercise $14.00 28,787 403,018 0 Mar 21, 2014, 01:29 PM
ATWOOD BRIAN G Director Mar 19, 2014 Option Exercise $14.00 61,124 855,736 0 Mar 21, 2014, 01:29 PM
ATWOOD BRIAN G Director Mar 19, 2014 Option Exercise $14.00 10,618 148,652 0 Mar 21, 2014, 01:29 PM
ATWOOD BRIAN G Director Mar 19, 2014 Option Exercise $14.00 1,685,591 23,598,274 0 Mar 21, 2014, 01:29 PM
ATWOOD BRIAN G Director Mar 19, 2014 Option Exercise $14.00 3,220,948 45,093,272 0 Mar 21, 2014, 01:29 PM
Schroeder Theodore R President, CEO Mar 19, 2014 Option Exercise $14.00 307,500 4,305,000 0 Mar 21, 2014, 01:28 PM
Schroeder Theodore R President, CEO Mar 19, 2014 Option Exercise $14.00 12,664 177,296 0 Mar 21, 2014, 01:28 PM
Lloyd-Smith Malcolm SVP, Reg Affairs, Qual & Clin Mar 19, 2014 Option Exercise $14.00 2,332 32,648 0 Mar 21, 2014, 01:26 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Mar 19, 2014 Option Exercise $14.00 5,000 70,000 0 Mar 21, 2014, 01:24 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Mar 19, 2014 Option Exercise $14.00 11,000 154,000 0 Mar 21, 2014, 01:24 PM
Byrd Scott A. SVP, Chief Commercial Officer Mar 19, 2014 Option Exercise $14.00 2,000 28,000 0 Mar 21, 2014, 01:22 PM
AKER HAZEL M SVP, GC & Secretary Mar 19, 2014 Option Exercise $14.00 3,745 52,430 0 Mar 21, 2014, 01:20 PM
ATWOOD BRIAN G Director Feb 12, 2014 Option Exercise $14.00 386,857 5,415,998 1,685,591 Feb 21, 2014, 05:13 PM
ATWOOD BRIAN G Director Feb 12, 2014 Option Exercise $14.00 2,438 34,132 10,618 Feb 21, 2014, 05:13 PM
ATWOOD BRIAN G Director Feb 12, 2014 Option Exercise $7.84 4,352 34,120 13,056 Feb 21, 2014, 05:13 PM
ATWOOD BRIAN G Director Feb 12, 2014 Option Exercise $7.84 690,816 5,415,998 2,072,448 Feb 21, 2014, 05:13 PM
FRAZIER ALAN D Director Feb 12, 2014 Option Exercise $14.00 875,913 12,262,782 3,816,474 Feb 21, 2014, 05:11 PM
FRAZIER ALAN D Director Feb 12, 2014 Option Exercise $14.00 97,324 1,362,536 4,796,711 Feb 21, 2014, 05:11 PM
FRAZIER ALAN D Director Feb 12, 2014 Option Exercise $7.84 173,792 1,362,529 4,894,035 Feb 21, 2014, 05:11 PM
FRAZIER ALAN D Director Feb 12, 2014 Option Exercise $7.84 1,564,129 12,262,772 4,692,387 Feb 21, 2014, 05:11 PM
DOMAIN PARTERS VII L P 10% Owner Feb 12, 2014 Option Exercise $14.00 765,532 10,717,448 2,972,678 Feb 14, 2014, 05:05 PM
DOMAIN PARTERS VII L P 10% Owner Feb 12, 2014 Option Exercise $7.84 1,367,020 10,717,437 3,738,210 Feb 14, 2014, 05:05 PM
DP VII ASSOCIATES LP 10% Owner Feb 12, 2014 Option Exercise $14.00 13,058 182,812 50,743 Feb 14, 2014, 05:03 PM
DP VII ASSOCIATES LP 10% Owner Feb 12, 2014 Option Exercise $7.84 23,317 182,805 63,801 Feb 14, 2014, 05:03 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Dec 17, 2013 Option Exercise $3.20 8,500 27,200 13,500 Dec 18, 2013, 04:25 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Dec 17, 2013 Sale $9.12 8,500 77,520 5,000 Dec 18, 2013, 04:25 PM
AKER HAZEL M SVP, GC & Secretary Dec 16, 2013 Option Exercise $3.51 13,014 45,679 16,759 Dec 18, 2013, 04:22 PM
AKER HAZEL M SVP, GC & Secretary Dec 16, 2013 Sale $8.76 13,014 114,003 3,745 Dec 18, 2013, 04:22 PM
Byrd Scott A. SVP, Chief Commercial Officer Dec 02, 2013 Option Exercise $3.51 7,812 27,420 9,812 Dec 03, 2013, 06:05 PM
Byrd Scott A. SVP, Chief Commercial Officer Dec 02, 2013 Sale $9.16 7,812 71,558 2,000 Dec 03, 2013, 06:05 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Nov 15, 2013 Option Exercise $3.20 27,000 86,400 32,000 Nov 18, 2013, 06:42 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Nov 18, 2013 Option Exercise $3.20 9,000 28,800 14,000 Nov 18, 2013, 06:42 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Nov 18, 2013 Sale $7.60 9,000 68,400 5,000 Nov 18, 2013, 06:42 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Nov 15, 2013 Sale $7.20 27,000 194,400 5,000 Nov 18, 2013, 06:42 PM
Byrd Scott A. SVP, Chief Commercial Officer Nov 15, 2013 Option Exercise $3.51 10,416 36,560 12,416 Nov 18, 2013, 06:39 PM
Byrd Scott A. SVP, Chief Commercial Officer Nov 15, 2013 Sale $8.00 10,416 83,328 2,000 Nov 18, 2013, 06:39 PM
AKER HAZEL M SVP, GC & Secretary Nov 15, 2013 Option Exercise $3.51 52,056 182,717 55,801 Nov 18, 2013, 06:36 PM
AKER HAZEL M SVP, GC & Secretary Nov 15, 2013 Sale $7.40 52,056 385,475 29,773 Nov 18, 2013, 06:36 PM
Lloyd-Smith Malcolm SVP, Reg Affairs, Qual & Clin Jul 22, 2013 Option Exercise $3.51 14,000 49,140 16,332 Jul 23, 2013, 07:00 PM
Lloyd-Smith Malcolm SVP, Reg Affairs, Qual & Clin Jul 22, 2013 Sale $7.85 14,000 109,900 2,332 Jul 23, 2013, 07:00 PM
AKER HAZEL M SVP, GC & Secretary Jul 22, 2013 Option Exercise $3.51 6,507 22,840 10,252 Jul 23, 2013, 06:59 PM
AKER HAZEL M SVP, GC & Secretary Jul 22, 2013 Sale $7.81 6,507 50,820 3,745 Jul 23, 2013, 06:59 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Jul 17, 2013 Option Exercise $3.20 9,000 28,800 14,000 Jul 17, 2013, 04:25 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Jul 17, 2013 Sale $7.26 9,000 65,299 5,000 Jul 17, 2013, 04:25 PM
AKER HAZEL M SVP, GC & Secretary Jul 15, 2013 Option Exercise $3.51 6,508 22,843 10,253 Jul 17, 2013, 04:23 PM
AKER HAZEL M SVP, GC & Secretary Jul 15, 2013 Sale $7.34 6,508 47,780 3,745 Jul 17, 2013, 04:23 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Jun 25, 2013 Option Exercise $3.20 3,260 10,432 8,260 Jun 27, 2013, 04:35 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Jun 27, 2013 Option Exercise $3.20 5,740 18,368 10,740 Jun 27, 2013, 04:35 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Jun 27, 2013 Sale $7.20 5,740 41,328 5,000 Jun 27, 2013, 04:35 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Jun 25, 2013 Sale $7.20 3,260 23,472 5,000 Jun 27, 2013, 04:35 PM
Lloyd-Smith Malcolm SVP, Reg Affairs, Qual & Clin Jun 10, 2013 Sale $7.44 4,000 29,760 2,332 Jun 11, 2013, 05:15 PM
Byrd Scott A. SVP, Chief Commercial Officer Jun 07, 2013 Option Exercise $3.51 67,115 235,574 69,115 Jun 11, 2013, 05:13 PM
Byrd Scott A. SVP, Chief Commercial Officer Jun 07, 2013 Sale $7.53 67,115 505,201 2,000 Jun 11, 2013, 05:13 PM
DOMAIN PARTERS VII L P 10% Owner Apr 15, 2013 Sale $6.62 23,210 153,650 2,371,190 Apr 17, 2013, 05:27 PM
Domain Partners VI, L.P. 10% Owner Apr 15, 2013 Sale $6.62 71,578 473,846 7,313,241 Apr 17, 2013, 05:14 PM
DOMAIN PARTERS VII L P 10% Owner Apr 10, 2013 Sale $6.72 1,567 10,530 2,394,400 Apr 10, 2013, 04:49 PM
DOMAIN PARTERS VII L P 10% Owner Apr 09, 2013 Sale $6.71 11,386 76,400 2,395,967 Apr 10, 2013, 04:49 PM
DOMAIN PARTERS VII L P 10% Owner Apr 08, 2013 Sale $6.52 12,217 79,655 2,407,353 Apr 10, 2013, 04:49 PM
Domain Partners VI, L.P. 10% Owner Apr 10, 2013 Sale $6.72 4,832 32,471 7,384,819 Apr 10, 2013, 04:47 PM
Domain Partners VI, L.P. 10% Owner Apr 09, 2013 Sale $6.71 35,114 235,615 7,389,651 Apr 10, 2013, 04:47 PM
Domain Partners VI, L.P. 10% Owner Apr 08, 2013 Sale $6.52 37,676 245,648 7,424,765 Apr 10, 2013, 04:47 PM
DOMAIN PARTERS VII L P 10% Owner Mar 21, 2013 Sale $5.35 4,374 23,401 2,419,570 Mar 22, 2013, 08:28 PM
Domain Partners VI, L.P. 10% Owner Mar 21, 2013 Sale $5.35 13,490 72,171 7,462,441 Mar 22, 2013, 08:22 PM
DP VI Associates, L.P. 10% Owner Mar 21, 2013 Sale $5.49 1,743 9,569 78,369 Mar 22, 2013, 06:19 PM
DP VII ASSOCIATES LP 10% Owner Mar 21, 2013 Sale $5.49 893 4,903 40,484 Mar 22, 2013, 06:16 PM
DP VI Associates, L.P. 10% Owner Mar 19, 2013 Sale $5.19 261 1,355 80,294 Mar 21, 2013, 05:13 PM
DP VI Associates, L.P. 10% Owner Mar 20, 2013 Sale $5.22 182 950 80,112 Mar 21, 2013, 05:13 PM
DP VII ASSOCIATES LP 10% Owner Mar 20, 2013 Sale $5.22 92 480 41,377 Mar 21, 2013, 05:10 PM
DP VII ASSOCIATES LP 10% Owner Mar 19, 2013 Sale $5.19 134 695 41,469 Mar 21, 2013, 05:10 PM
Domain Partners VI, L.P. 10% Owner Mar 19, 2013 Sale $5.19 24,442 126,854 7,492,926 Mar 21, 2013, 05:02 PM
Domain Partners VI, L.P. 10% Owner Mar 20, 2013 Sale $5.22 16,995 88,714 7,475,931 Mar 21, 2013, 05:02 PM
DOMAIN PARTERS VII L P 10% Owner Mar 20, 2013 Sale $5.22 5,510 28,762 2,423,944 Mar 21, 2013, 04:58 PM
DOMAIN PARTERS VII L P 10% Owner Mar 19, 2013 Sale $5.19 7,925 41,131 2,429,454 Mar 21, 2013, 04:58 PM
DP VI Associates, L.P. 10% Owner Mar 15, 2013 Sale $5.28 318 1,679 80,820 Mar 19, 2013, 04:47 PM
DP VI Associates, L.P. 10% Owner Mar 18, 2013 Sale $5.16 265 1,367 80,555 Mar 19, 2013, 04:47 PM
DP VII ASSOCIATES LP 10% Owner Mar 18, 2013 Sale $5.16 135 697 41,603 Mar 19, 2013, 04:43 PM
DP VII ASSOCIATES LP 10% Owner Mar 15, 2013 Sale $5.28 163 861 41,738 Mar 19, 2013, 04:43 PM
Domain Partners VI, L.P. 10% Owner Mar 15, 2013 Sale $5.28 29,719 156,916 7,542,104 Mar 19, 2013, 04:39 PM
Domain Partners VI, L.P. 10% Owner Mar 18, 2013 Sale $5.16 24,736 127,638 7,517,368 Mar 19, 2013, 04:39 PM
DOMAIN PARTERS VII L P 10% Owner Mar 18, 2013 Sale $5.16 8,020 41,383 2,437,379 Mar 19, 2013, 04:34 PM
DOMAIN PARTERS VII L P 10% Owner Mar 15, 2013 Sale $5.28 9,636 50,878 2,445,399 Mar 19, 2013, 04:34 PM
DP VI Associates, L.P. 10% Owner Mar 13, 2013 Sale $5.40 256 1,382 81,304 Mar 15, 2013, 05:02 PM
DP VI Associates, L.P. 10% Owner Mar 14, 2013 Sale $5.36 166 890 81,138 Mar 15, 2013, 05:02 PM
DP VII ASSOCIATES LP 10% Owner Mar 14, 2013 Sale $5.36 85 456 41,901 Mar 15, 2013, 04:59 PM
DP VII ASSOCIATES LP 10% Owner Mar 13, 2013 Sale $5.40 131 707 41,986 Mar 15, 2013, 04:59 PM
Domain Partners VI, L.P. 10% Owner Mar 13, 2013 Sale $5.40 23,848 128,779 7,587,303 Mar 15, 2013, 04:57 PM
Domain Partners VI, L.P. 10% Owner Mar 14, 2013 Sale $5.36 15,480 82,973 7,571,823 Mar 15, 2013, 04:57 PM
DOMAIN PARTERS VII L P 10% Owner Mar 13, 2013 Sale $5.40 7,733 41,758 2,460,055 Mar 15, 2013, 04:55 PM
DOMAIN PARTERS VII L P 10% Owner Mar 14, 2013 Sale $5.36 5,020 26,907 2,455,035 Mar 15, 2013, 04:55 PM
DP VI Associates, L.P. 10% Owner Mar 12, 2013 Sale $5.38 210 1,130 81,560 Mar 13, 2013, 08:40 PM
DP VI Associates, L.P. 10% Owner Mar 11, 2013 Sale $5.34 136 726 81,770 Mar 13, 2013, 08:40 PM
DP VII ASSOCIATES LP 10% Owner Mar 11, 2013 Sale $5.34 70 374 42,224 Mar 13, 2013, 08:38 PM
DP VII ASSOCIATES LP 10% Owner Mar 12, 2013 Sale $5.38 107 576 42,117 Mar 13, 2013, 08:38 PM
Domain Partners VI, L.P. 10% Owner Mar 12, 2013 Sale $5.38 19,569 105,281 7,611,151 Mar 13, 2013, 08:36 PM
Domain Partners VI, L.P. 10% Owner Mar 11, 2013 Sale $5.34 12,700 67,818 7,630,720 Mar 13, 2013, 08:36 PM
DOMAIN PARTERS VII L P 10% Owner Mar 11, 2013 Sale $5.34 4,118 21,990 2,474,134 Mar 13, 2013, 08:33 PM
DOMAIN PARTERS VII L P 10% Owner Mar 12, 2013 Sale $5.38 6,346 34,141 2,467,788 Mar 13, 2013, 08:33 PM
DP VI Associates, L.P. 10% Owner Mar 08, 2013 Sale $5.32 171 910 81,906 Mar 11, 2013, 06:39 PM
DP VI Associates, L.P. 10% Owner Mar 07, 2013 Sale $5.22 420 2,192 82,077 Mar 11, 2013, 06:39 PM
DP VII ASSOCIATES LP 10% Owner Mar 07, 2013 Sale $5.22 215 1,122 42,382 Mar 11, 2013, 06:35 PM
DP VII ASSOCIATES LP 10% Owner Mar 08, 2013 Sale $5.32 88 468 42,294 Mar 11, 2013, 06:35 PM
Domain Partners VI, L.P. 10% Owner Mar 08, 2013 Sale $5.32 15,892 84,545 7,643,420 Mar 11, 2013, 06:32 PM
Domain Partners VI, L.P. 10% Owner Mar 07, 2013 Sale $5.22 39,168 204,457 7,659,312 Mar 11, 2013, 06:32 PM
DOMAIN PARTERS VII L P 10% Owner Mar 07, 2013 Sale $5.22 12,701 66,299 2,483,406 Mar 11, 2013, 06:29 PM
DOMAIN PARTERS VII L P 10% Owner Mar 08, 2013 Sale $5.32 5,154 27,419 2,478,252 Mar 11, 2013, 06:29 PM
Domain Partners VI, L.P. 10% Owner Mar 06, 2013 Sale $5.06 11,841 59,915 7,698,480 Mar 07, 2013, 06:22 PM
Domain Partners VI, L.P. 10% Owner Mar 05, 2013 Sale $5.01 12,454 62,395 7,710,321 Mar 07, 2013, 06:22 PM
DOMAIN PARTERS VII L P 10% Owner Mar 05, 2013 Sale $5.01 4,039 20,235 2,499,946 Mar 07, 2013, 06:19 PM
DOMAIN PARTERS VII L P 10% Owner Mar 06, 2013 Sale $5.06 3,839 19,425 2,496,107 Mar 07, 2013, 06:19 PM
DP VI Associates, L.P. 10% Owner Mar 06, 2013 Sale $5.06 127 643 82,497 Mar 07, 2013, 06:15 PM
DP VI Associates, L.P. 10% Owner Mar 05, 2013 Sale $5.01 134 671 82,624 Mar 07, 2013, 06:15 PM
DP VII ASSOCIATES LP 10% Owner Mar 05, 2013 Sale $5.01 69 346 42,662 Mar 07, 2013, 06:12 PM
DP VII ASSOCIATES LP 10% Owner Mar 06, 2013 Sale $5.06 65 329 42,597 Mar 07, 2013, 06:12 PM
DP VII ASSOCIATES LP 10% Owner Mar 04, 2013 Sale $5.01 88 441 42,731 Mar 05, 2013, 05:18 PM
DP VII ASSOCIATES LP 10% Owner Mar 01, 2013 Sale $5.01 130 651 42,819 Mar 05, 2013, 05:18 PM
DP VI Associates, L.P. 10% Owner Mar 04, 2013 Sale $5.01 170 852 82,758 Mar 05, 2013, 05:12 PM
DP VI Associates, L.P. 10% Owner Mar 01, 2013 Sale $5.01 253 1,268 82,928 Mar 05, 2013, 05:12 PM
DOMAIN PARTERS VII L P 10% Owner Mar 01, 2013 Sale $5.01 7,635 38,251 2,509,130 Mar 05, 2013, 05:06 PM
DOMAIN PARTERS VII L P 10% Owner Mar 04, 2013 Sale $5.01 5,145 25,776 2,503,985 Mar 05, 2013, 05:06 PM
Domain Partners VI, L.P. 10% Owner Mar 04, 2013 Sale $5.01 15,865 79,484 7,722,775 Mar 05, 2013, 05:02 PM
Domain Partners VI, L.P. 10% Owner Mar 01, 2013 Sale $5.01 23,548 117,975 7,738,640 Mar 05, 2013, 05:02 PM
Domain Partners VI, L.P. 10% Owner Feb 20, 2013 Sale $5.01 6,160 30,862 7,762,188 Feb 22, 2013, 04:58 PM
DP VII ASSOCIATES LP 10% Owner Feb 20, 2013 Sale $5.01 34 170 42,949 Feb 22, 2013, 04:53 PM
DP VI Associates, L.P. 10% Owner Feb 20, 2013 Sale $5.01 66 331 83,181 Feb 22, 2013, 04:50 PM
DOMAIN PARTERS VII L P 10% Owner Feb 20, 2013 Sale $5.01 1,998 10,010 2,516,765 Feb 22, 2013, 04:46 PM
DP VII ASSOCIATES LP 10% Owner Feb 15, 2013 Sale $5.00 51 255 43,154 Feb 20, 2013, 04:55 PM
DP VII ASSOCIATES LP 10% Owner Feb 19, 2013 Sale $5.02 171 858 42,983 Feb 20, 2013, 04:55 PM
DOMAIN PARTERS VII L P 10% Owner Feb 15, 2013 Sale $5.00 2,967 14,835 2,528,839 Feb 20, 2013, 04:52 PM
DOMAIN PARTERS VII L P 10% Owner Feb 19, 2013 Sale $5.02 10,076 50,582 2,518,763 Feb 20, 2013, 04:52 PM
DP VI Associates, L.P. 10% Owner Feb 19, 2013 Sale $5.02 334 1,677 83,247 Feb 20, 2013, 04:47 PM
DP VI Associates, L.P. 10% Owner Feb 15, 2013 Sale $5.00 99 495 83,581 Feb 20, 2013, 04:47 PM
Domain Partners VI, L.P. 10% Owner Feb 19, 2013 Sale $5.02 31,075 155,996 7,768,348 Feb 20, 2013, 04:43 PM
Domain Partners VI, L.P. 10% Owner Feb 15, 2013 Sale $5.00 9,148 45,740 7,799,423 Feb 20, 2013, 04:43 PM
DP VII ASSOCIATES LP 10% Owner Feb 13, 2013 Sale $5.00 98 490 43,256 Feb 15, 2013, 05:12 PM
DP VII ASSOCIATES LP 10% Owner Feb 14, 2013 Sale $5.01 51 256 43,205 Feb 15, 2013, 05:12 PM
DP VI Associates, L.P. 10% Owner Feb 14, 2013 Sale $5.01 98 491 83,680 Feb 15, 2013, 05:08 PM
DP VI Associates, L.P. 10% Owner Feb 13, 2013 Sale $5.00 191 955 83,778 Feb 15, 2013, 05:08 PM
DOMAIN PARTERS VII L P 10% Owner Feb 13, 2013 Sale $5.00 5,763 28,815 2,534,757 Feb 15, 2013, 05:03 PM
DOMAIN PARTERS VII L P 10% Owner Feb 14, 2013 Sale $5.01 2,951 14,785 2,531,806 Feb 15, 2013, 05:03 PM
Domain Partners VI, L.P. 10% Owner Feb 13, 2013 Sale $5.00 17,770 88,850 7,817,671 Feb 15, 2013, 04:57 PM
Domain Partners VI, L.P. 10% Owner Feb 14, 2013 Sale $5.01 9,100 45,591 7,808,571 Feb 15, 2013, 04:57 PM
Domain Partners VI, L.P. 10% Owner Feb 01, 2013 Sale $4.85 30,134 146,150 7,835,441 Feb 05, 2013, 06:19 PM
DP VII ASSOCIATES LP 10% Owner Feb 01, 2013 Sale $4.85 164 795 43,354 Feb 05, 2013, 06:16 PM
DP VI Associates, L.P. 10% Owner Feb 01, 2013 Sale $4.85 322 1,562 83,969 Feb 05, 2013, 06:14 PM
DOMAIN PARTERS VII L P 10% Owner Feb 01, 2013 Sale $4.85 9,769 47,380 2,540,520 Feb 05, 2013, 06:11 PM
Domain Partners VI, L.P. 10% Owner Jan 31, 2013 Sale $4.71 57,165 269,247 7,865,575 Feb 01, 2013, 05:28 PM
Domain Partners VI, L.P. 10% Owner Jan 30, 2013 Sale $5.00 34,248 171,240 7,922,740 Feb 01, 2013, 05:28 PM
DOMAIN PARTERS VII L P 10% Owner Jan 31, 2013 Sale $4.71 18,537 87,309 2,550,289 Feb 01, 2013, 05:25 PM
DOMAIN PARTERS VII L P 10% Owner Jan 30, 2013 Sale $5.00 11,105 55,525 2,568,826 Feb 01, 2013, 05:25 PM
DP VI Associates, L.P. 10% Owner Jan 31, 2013 Sale $4.71 613 2,887 84,291 Feb 01, 2013, 05:22 PM
DP VI Associates, L.P. 10% Owner Jan 30, 2013 Sale $5.00 367 1,835 84,904 Feb 01, 2013, 05:22 PM
DP VII ASSOCIATES LP 10% Owner Jan 31, 2013 Sale $4.71 314 1,479 43,518 Feb 01, 2013, 04:53 PM
DP VII ASSOCIATES LP 10% Owner Jan 30, 2013 Sale $5.00 188 940 43,832 Feb 01, 2013, 04:53 PM
Domain Partners VI, L.P. 10% Owner Jan 29, 2013 Sale $5.27 47,247 248,992 7,956,988 Jan 30, 2013, 07:25 PM
Domain Partners VI, L.P. 10% Owner Jan 28, 2013 Sale $5.40 51,377 277,436 8,004,235 Jan 30, 2013, 07:25 PM
DOMAIN PARTERS VII L P 10% Owner Jan 29, 2013 Sale $5.27 15,320 80,736 2,579,931 Jan 30, 2013, 07:20 PM
DOMAIN PARTERS VII L P 10% Owner Jan 28, 2013 Sale $5.40 16,660 89,964 2,595,251 Jan 30, 2013, 07:20 PM
DP VII ASSOCIATES LP 10% Owner Jan 29, 2013 Sale $5.27 260 1,370 44,020 Jan 30, 2013, 07:18 PM
DP VII ASSOCIATES LP 10% Owner Jan 28, 2013 Sale $5.40 282 1,523 44,280 Jan 30, 2013, 07:18 PM
DP VI Associates, L.P. 10% Owner Jan 29, 2013 Sale $5.27 507 2,672 85,271 Jan 30, 2013, 07:14 PM
DP VI Associates, L.P. 10% Owner Jan 28, 2013 Sale $5.40 551 2,975 85,778 Jan 30, 2013, 07:14 PM
Domain Partners VI, L.P. 10% Owner Jan 25, 2013 Sale $5.38 42,525 228,785 8,055,612 Jan 29, 2013, 04:11 PM
Domain Partners VI, L.P. 10% Owner Jan 24, 2013 Sale $5.45 112,022 610,520 8,098,137 Jan 29, 2013, 04:11 PM
DP VI Associates, L.P. 10% Owner Jan 25, 2013 Sale $5.38 456 2,453 86,329 Jan 28, 2013, 07:45 PM
DP VI Associates, L.P. 10% Owner Jan 24, 2013 Sale $5.45 1,201 6,545 86,785 Jan 28, 2013, 07:45 PM
Domain Partners VI, L.P. 10% Owner Jan 25, 2013 Sale $5.38 42,525 228,785 8,055,612 Jan 28, 2013, 07:41 PM
Domain Partners VI, L.P. 10% Owner Jan 24, 2013 Sale $5.45 111,022 605,070 8,098,137 Jan 28, 2013, 07:41 PM
DP VII ASSOCIATES LP 10% Owner Jan 25, 2013 Sale $5.38 234 1,259 44,562 Jan 28, 2013, 07:35 PM
DP VII ASSOCIATES LP 10% Owner Jan 24, 2013 Sale $5.45 616 3,357 44,796 Jan 28, 2013, 07:35 PM
DOMAIN PARTERS VII L P 10% Owner Jan 25, 2013 Sale $5.38 13,790 74,190 2,611,911 Jan 28, 2013, 07:12 PM
DOMAIN PARTERS VII L P 10% Owner Jan 24, 2013 Sale $5.45 36,324 197,966 2,625,701 Jan 28, 2013, 07:12 PM
DP VI Associates, L.P. 10% Owner Jan 23, 2013 Sale $5.11 839 4,287 87,986 Jan 24, 2013, 04:41 PM
DP VI Associates, L.P. 10% Owner Jan 22, 2013 Sale $5.02 495 2,485 88,825 Jan 24, 2013, 04:41 PM
Domain Partners VI, L.P. 10% Owner Jan 23, 2013 Sale $5.11 78,188 399,541 8,210,159 Jan 24, 2013, 04:38 PM
Domain Partners VI, L.P. 10% Owner Jan 22, 2013 Sale $5.02 46,153 231,688 8,288,347 Jan 24, 2013, 04:38 PM
DP VII ASSOCIATES LP 10% Owner Jan 23, 2013 Sale $5.11 430 2,197 45,412 Jan 24, 2013, 04:34 PM
DP VII ASSOCIATES LP 10% Owner Jan 22, 2013 Sale $5.02 254 1,275 45,842 Jan 24, 2013, 04:34 PM
DOMAIN PARTERS VII L P 10% Owner Jan 23, 2013 Sale $5.11 25,354 129,559 2,662,025 Jan 24, 2013, 04:31 PM
DOMAIN PARTERS VII L P 10% Owner Jan 22, 2013 Sale $5.02 14,966 75,129 2,687,379 Jan 24, 2013, 04:31 PM
Domain Partners VI, L.P. 10% Owner Jan 18, 2013 Sale $5.19 58,838 305,369 8,334,500 Jan 22, 2013, 06:34 PM
Domain Partners VI, L.P. 10% Owner Jan 17, 2013 Sale $5.35 38,903 208,131 8,393,338 Jan 22, 2013, 06:34 PM
DOMAIN PARTERS VII L P 10% Owner Jan 18, 2013 Sale $5.19 19,080 99,025 2,702,345 Jan 22, 2013, 06:31 PM
DOMAIN PARTERS VII L P 10% Owner Jan 17, 2013 Sale $5.35 12,615 67,490 2,721,425 Jan 22, 2013, 06:31 PM
DP VI Associates, L.P. 10% Owner Jan 18, 2013 Sale $5.19 631 3,275 89,320 Jan 22, 2013, 06:28 PM
DP VI Associates, L.P. 10% Owner Jan 17, 2013 Sale $5.35 418 2,236 89,951 Jan 22, 2013, 06:28 PM
DP VII ASSOCIATES LP 10% Owner Jan 18, 2013 Sale $5.19 324 1,682 46,096 Jan 22, 2013, 06:23 PM
DP VII ASSOCIATES LP 10% Owner Jan 17, 2013 Sale $5.35 214 1,145 46,420 Jan 22, 2013, 06:23 PM
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Nov 21, 2011 Sale $4.16 10,000 41,632 5,000 Nov 22, 2011, 06:25 PM
AKER HAZEL M SVP, GC & Secretary Nov 21, 2011 Sale $4.16 10,000 41,621 3,745 Nov 22, 2011, 06:23 PM
Schroeder Theodore R President, CEO Nov 02, 2011 Option Exercise $5.72 7,336 41,962 12,664 Nov 04, 2011, 04:45 PM
BREITMEYER JAMES B EVP, CMO Nov 03, 2011 Sale $5.70 12,500 71,304 10,000 Nov 04, 2011, 04:42 PM
BREITMEYER JAMES B EVP, CMO Jul 11, 2011 Option Exercise $3.20 3,000 9,600 13,000 Jul 12, 2011, 05:33 PM
BREITMEYER JAMES B EVP, CMO Jul 11, 2011 Sale $8.99 3,000 26,970 10,000 Jul 12, 2011, 05:33 PM
Schroeder Theodore R President, CEO May 17, 2011 Buy $7.48 16,000 119,626 307,500 May 17, 2011, 06:18 PM
Byrd Scott A. SVP, Chief Commercial Officer May 10, 2011 Buy $7.22 2,000 14,431 2,000 May 11, 2011, 04:53 PM
BARKER SAM L Director May 10, 2011 Buy $7.04 9,000 63,330 20,000 May 11, 2011, 04:51 PM
BREITMEYER JAMES B EVP, CMO May 02, 2011 Option Exercise $3.20 12,000 38,400 22,000 May 03, 2011, 06:22 PM
BREITMEYER JAMES B EVP, CMO May 02, 2011 Sale $8.35 12,000 100,163 10,000 May 03, 2011, 06:22 PM
BREITMEYER JAMES B EVP, CMO Apr 01, 2011 Option Exercise $3.20 7,000 22,400 17,000 Apr 05, 2011, 04:25 PM
BREITMEYER JAMES B EVP, CMO Apr 01, 2011 Sale $9.20 7,000 64,400 10,000 Apr 05, 2011, 04:25 PM
BREITMEYER JAMES B EVP, CMO Mar 04, 2011 Option Exercise $3.20 7,000 22,400 17,000 Mar 08, 2011, 04:55 PM
BREITMEYER JAMES B EVP, CMO Mar 04, 2011 Sale $8.50 7,000 59,500 10,000 Mar 08, 2011, 04:55 PM
BREITMEYER JAMES B EVP, CMO Feb 03, 2011 Option Exercise $3.20 39,000 124,800 49,000 Feb 04, 2011, 06:22 PM
BREITMEYER JAMES B EVP, CMO Feb 03, 2011 Sale $7.39 39,000 288,015 10,000 Feb 04, 2011, 06:22 PM
BREITMEYER JAMES B EVP, CMO Nov 02, 2010 Option Exercise $3.20 18,000 57,600 28,000 Nov 03, 2010, 04:42 PM
BREITMEYER JAMES B EVP, CMO Nov 01, 2010 Option Exercise $3.20 7,000 22,400 17,000 Nov 03, 2010, 04:42 PM
BREITMEYER JAMES B EVP, CMO Nov 01, 2010 Sale $9.00 7,000 63,000 10,000 Nov 03, 2010, 04:42 PM
BREITMEYER JAMES B EVP, CMO Nov 02, 2010 Sale $9.05 18,000 162,857 10,000 Nov 03, 2010, 04:42 PM
BREITMEYER JAMES B EVP, CMO Oct 05, 2010 Option Exercise $3.20 7,000 22,400 17,000 Oct 06, 2010, 04:59 PM
BREITMEYER JAMES B EVP, CMO Oct 05, 2010 Sale $8.50 7,000 59,500 10,000 Oct 06, 2010, 04:59 PM
Schroeder Theodore R President, CEO Oct 01, 2010 Sale $8.35 9,297 77,670 311,000 Oct 04, 2010, 04:16 PM
Schroeder Theodore R President, CEO Sep 30, 2010 Sale $8.35 40,703 339,691 320,297 Oct 04, 2010, 04:16 PM
BREITMEYER JAMES B EVP, CMO Sep 27, 2010 Option Exercise $3.20 2,363 7,562 12,363 Sep 29, 2010, 06:37 PM
BREITMEYER JAMES B EVP, CMO Sep 29, 2010 Option Exercise $3.20 4,637 14,838 14,637 Sep 29, 2010, 06:37 PM
BREITMEYER JAMES B EVP, CMO Sep 27, 2010 Sale $8.50 2,363 20,086 10,000 Sep 29, 2010, 06:37 PM
BREITMEYER JAMES B EVP, CMO Sep 29, 2010 Sale $8.50 4,637 39,415 10,000 Sep 29, 2010, 06:37 PM

Desktop Version

Owner Relationship Date Transaction Value($)
Kamdar Kim P. 10% Owner Mar 19, 2014 Option Exercise 385,000
TREU JESSE I 10% Owner Mar 19, 2014 Option Exercise 1,097,166
TREU JESSE I 10% Owner Mar 19, 2014 Option Exercise 102,385,374
TREU JESSE I 10% Owner Mar 19, 2014 Option Exercise 710,402
TREU JESSE I 10% Owner Mar 19, 2014 Option Exercise 41,617,492
TREU JESSE I 10% Owner Mar 19, 2014 Option Exercise 385,000
Halak Brian K 10% Owner Mar 19, 2014 Option Exercise 385,000
Halak Brian K 10% Owner Mar 19, 2014 Option Exercise 710,402
Halak Brian K 10% Owner Mar 19, 2014 Option Exercise 41,617,492
DOMAIN ASSOCIATES 10% Owner Mar 19, 2014 Option Exercise 385,000
Domain Partners VI, L.P. 10% Owner Mar 19, 2014 Option Exercise 102,385,374
VITULLO NICOLE 10% Owner Mar 19, 2014 Option Exercise 710,402
VITULLO NICOLE 10% Owner Mar 19, 2014 Option Exercise 41,617,492
VITULLO NICOLE 10% Owner Mar 19, 2014 Option Exercise 385,000
VITULLO NICOLE 10% Owner Mar 19, 2014 Option Exercise 1,097,166
VITULLO NICOLE 10% Owner Mar 19, 2014 Option Exercise 102,385,374
DP VI Associates, L.P. 10% Owner Mar 19, 2014 Option Exercise 1,097,166
BLAIR JAMES C Director Mar 19, 2014 Option Exercise 1,097,166
BLAIR JAMES C Director Mar 19, 2014 Option Exercise 102,385,374
BLAIR JAMES C Director Mar 19, 2014 Option Exercise 710,402
BLAIR JAMES C Director Mar 19, 2014 Option Exercise 41,617,492
BLAIR JAMES C Director Mar 19, 2014 Option Exercise 385,000
DOVEY BRIAN H 10% Owner Mar 19, 2014 Option Exercise 41,617,492
DOVEY BRIAN H 10% Owner Mar 19, 2014 Option Exercise 385,000
DOVEY BRIAN H 10% Owner Mar 19, 2014 Option Exercise 1,097,166
DOVEY BRIAN H 10% Owner Mar 19, 2014 Option Exercise 102,385,374
DOVEY BRIAN H 10% Owner Mar 19, 2014 Option Exercise 710,402
SCHOEMAKER KATHLEEN K 10% Owner Mar 19, 2014 Option Exercise 710,402
SCHOEMAKER KATHLEEN K 10% Owner Mar 19, 2014 Option Exercise 41,617,492
SCHOEMAKER KATHLEEN K 10% Owner Mar 19, 2014 Option Exercise 385,000
SCHOEMAKER KATHLEEN K 10% Owner Mar 19, 2014 Option Exercise 1,097,166
SCHOEMAKER KATHLEEN K 10% Owner Mar 19, 2014 Option Exercise 102,385,374
DOMAIN PARTERS VII L P 10% Owner Mar 19, 2014 Option Exercise 41,617,492
DP VII ASSOCIATES LP 10% Owner Mar 19, 2014 Option Exercise 710,402
TWOMEY CHRISTOPHER J Director Mar 19, 2014 Option Exercise 490,000
TWOMEY CHRISTOPHER J Director Mar 19, 2014 Option Exercise 350,000
Rich Todd W Director Mar 19, 2014 Option Exercise 140,000
GARNER CAM L Director Mar 19, 2014 Option Exercise 6,812,330
GARNER CAM L Director Mar 19, 2014 Option Exercise 7,572,432
FRAZIER ALAN D Director Mar 19, 2014 Option Exercise 67,153,954
FRAZIER ALAN D Director Mar 19, 2014 Option Exercise 53,430,636
BARKER SAM L Director Mar 19, 2014 Option Exercise 280,000
ATWOOD BRIAN G Director Mar 19, 2014 Option Exercise 403,018
ATWOOD BRIAN G Director Mar 19, 2014 Option Exercise 855,736
ATWOOD BRIAN G Director Mar 19, 2014 Option Exercise 148,652
ATWOOD BRIAN G Director Mar 19, 2014 Option Exercise 23,598,274
ATWOOD BRIAN G Director Mar 19, 2014 Option Exercise 45,093,272
Schroeder Theodore R President, CEO Mar 19, 2014 Option Exercise 4,305,000
Schroeder Theodore R President, CEO Mar 19, 2014 Option Exercise 177,296
Lloyd-Smith Malcolm SVP, Reg Affairs, Qual & Clin Mar 19, 2014 Option Exercise 32,648
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Mar 19, 2014 Option Exercise 70,000
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Mar 19, 2014 Option Exercise 154,000
Byrd Scott A. SVP, Chief Commercial Officer Mar 19, 2014 Option Exercise 28,000
AKER HAZEL M SVP, GC & Secretary Mar 19, 2014 Option Exercise 52,430
ATWOOD BRIAN G Director Feb 12, 2014 Option Exercise 5,415,998
ATWOOD BRIAN G Director Feb 12, 2014 Option Exercise 34,132
ATWOOD BRIAN G Director Feb 12, 2014 Option Exercise 34,120
ATWOOD BRIAN G Director Feb 12, 2014 Option Exercise 5,415,998
FRAZIER ALAN D Director Feb 12, 2014 Option Exercise 12,262,782
FRAZIER ALAN D Director Feb 12, 2014 Option Exercise 1,362,536
FRAZIER ALAN D Director Feb 12, 2014 Option Exercise 1,362,529
FRAZIER ALAN D Director Feb 12, 2014 Option Exercise 12,262,772
DOMAIN PARTERS VII L P 10% Owner Feb 12, 2014 Option Exercise 10,717,448
DOMAIN PARTERS VII L P 10% Owner Feb 12, 2014 Option Exercise 10,717,437
DP VII ASSOCIATES LP 10% Owner Feb 12, 2014 Option Exercise 182,812
DP VII ASSOCIATES LP 10% Owner Feb 12, 2014 Option Exercise 182,805
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Dec 17, 2013 Option Exercise 27,200
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Dec 17, 2013 Sale 77,520
AKER HAZEL M SVP, GC & Secretary Dec 16, 2013 Option Exercise 45,679
AKER HAZEL M SVP, GC & Secretary Dec 16, 2013 Sale 114,003
Byrd Scott A. SVP, Chief Commercial Officer Dec 02, 2013 Option Exercise 27,420
Byrd Scott A. SVP, Chief Commercial Officer Dec 02, 2013 Sale 71,558
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Nov 15, 2013 Option Exercise 86,400
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Nov 18, 2013 Option Exercise 28,800
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Nov 18, 2013 Sale 68,400
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Nov 15, 2013 Sale 194,400
Byrd Scott A. SVP, Chief Commercial Officer Nov 15, 2013 Option Exercise 36,560
Byrd Scott A. SVP, Chief Commercial Officer Nov 15, 2013 Sale 83,328
AKER HAZEL M SVP, GC & Secretary Nov 15, 2013 Option Exercise 182,717
AKER HAZEL M SVP, GC & Secretary Nov 15, 2013 Sale 385,475
Lloyd-Smith Malcolm SVP, Reg Affairs, Qual & Clin Jul 22, 2013 Option Exercise 49,140
Lloyd-Smith Malcolm SVP, Reg Affairs, Qual & Clin Jul 22, 2013 Sale 109,900
AKER HAZEL M SVP, GC & Secretary Jul 22, 2013 Option Exercise 22,840
AKER HAZEL M SVP, GC & Secretary Jul 22, 2013 Sale 50,820
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Jul 17, 2013 Option Exercise 28,800
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Jul 17, 2013 Sale 65,299
AKER HAZEL M SVP, GC & Secretary Jul 15, 2013 Option Exercise 22,843
AKER HAZEL M SVP, GC & Secretary Jul 15, 2013 Sale 47,780
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Jun 25, 2013 Option Exercise 10,432
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Jun 27, 2013 Option Exercise 18,368
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Jun 27, 2013 Sale 41,328
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Jun 25, 2013 Sale 23,472
Lloyd-Smith Malcolm SVP, Reg Affairs, Qual & Clin Jun 10, 2013 Sale 29,760
Byrd Scott A. SVP, Chief Commercial Officer Jun 07, 2013 Option Exercise 235,574
Byrd Scott A. SVP, Chief Commercial Officer Jun 07, 2013 Sale 505,201
DOMAIN PARTERS VII L P 10% Owner Apr 15, 2013 Sale 153,650
Domain Partners VI, L.P. 10% Owner Apr 15, 2013 Sale 473,846
DOMAIN PARTERS VII L P 10% Owner Apr 10, 2013 Sale 10,530
DOMAIN PARTERS VII L P 10% Owner Apr 09, 2013 Sale 76,400
DOMAIN PARTERS VII L P 10% Owner Apr 08, 2013 Sale 79,655
Domain Partners VI, L.P. 10% Owner Apr 10, 2013 Sale 32,471
Domain Partners VI, L.P. 10% Owner Apr 09, 2013 Sale 235,615
Domain Partners VI, L.P. 10% Owner Apr 08, 2013 Sale 245,648
DOMAIN PARTERS VII L P 10% Owner Mar 21, 2013 Sale 23,401
Domain Partners VI, L.P. 10% Owner Mar 21, 2013 Sale 72,171
DP VI Associates, L.P. 10% Owner Mar 21, 2013 Sale 9,569
DP VII ASSOCIATES LP 10% Owner Mar 21, 2013 Sale 4,903
DP VI Associates, L.P. 10% Owner Mar 19, 2013 Sale 1,355
DP VI Associates, L.P. 10% Owner Mar 20, 2013 Sale 950
DP VII ASSOCIATES LP 10% Owner Mar 20, 2013 Sale 480
DP VII ASSOCIATES LP 10% Owner Mar 19, 2013 Sale 695
Domain Partners VI, L.P. 10% Owner Mar 19, 2013 Sale 126,854
Domain Partners VI, L.P. 10% Owner Mar 20, 2013 Sale 88,714
DOMAIN PARTERS VII L P 10% Owner Mar 20, 2013 Sale 28,762
DOMAIN PARTERS VII L P 10% Owner Mar 19, 2013 Sale 41,131
DP VI Associates, L.P. 10% Owner Mar 15, 2013 Sale 1,679
DP VI Associates, L.P. 10% Owner Mar 18, 2013 Sale 1,367
DP VII ASSOCIATES LP 10% Owner Mar 18, 2013 Sale 697
DP VII ASSOCIATES LP 10% Owner Mar 15, 2013 Sale 861
Domain Partners VI, L.P. 10% Owner Mar 15, 2013 Sale 156,916
Domain Partners VI, L.P. 10% Owner Mar 18, 2013 Sale 127,638
DOMAIN PARTERS VII L P 10% Owner Mar 18, 2013 Sale 41,383
DOMAIN PARTERS VII L P 10% Owner Mar 15, 2013 Sale 50,878
DP VI Associates, L.P. 10% Owner Mar 13, 2013 Sale 1,382
DP VI Associates, L.P. 10% Owner Mar 14, 2013 Sale 890
DP VII ASSOCIATES LP 10% Owner Mar 14, 2013 Sale 456
DP VII ASSOCIATES LP 10% Owner Mar 13, 2013 Sale 707
Domain Partners VI, L.P. 10% Owner Mar 13, 2013 Sale 128,779
Domain Partners VI, L.P. 10% Owner Mar 14, 2013 Sale 82,973
DOMAIN PARTERS VII L P 10% Owner Mar 13, 2013 Sale 41,758
DOMAIN PARTERS VII L P 10% Owner Mar 14, 2013 Sale 26,907
DP VI Associates, L.P. 10% Owner Mar 12, 2013 Sale 1,130
DP VI Associates, L.P. 10% Owner Mar 11, 2013 Sale 726
DP VII ASSOCIATES LP 10% Owner Mar 11, 2013 Sale 374
DP VII ASSOCIATES LP 10% Owner Mar 12, 2013 Sale 576
Domain Partners VI, L.P. 10% Owner Mar 12, 2013 Sale 105,281
Domain Partners VI, L.P. 10% Owner Mar 11, 2013 Sale 67,818
DOMAIN PARTERS VII L P 10% Owner Mar 11, 2013 Sale 21,990
DOMAIN PARTERS VII L P 10% Owner Mar 12, 2013 Sale 34,141
DP VI Associates, L.P. 10% Owner Mar 08, 2013 Sale 910
DP VI Associates, L.P. 10% Owner Mar 07, 2013 Sale 2,192
DP VII ASSOCIATES LP 10% Owner Mar 07, 2013 Sale 1,122
DP VII ASSOCIATES LP 10% Owner Mar 08, 2013 Sale 468
Domain Partners VI, L.P. 10% Owner Mar 08, 2013 Sale 84,545
Domain Partners VI, L.P. 10% Owner Mar 07, 2013 Sale 204,457
DOMAIN PARTERS VII L P 10% Owner Mar 07, 2013 Sale 66,299
DOMAIN PARTERS VII L P 10% Owner Mar 08, 2013 Sale 27,419
Domain Partners VI, L.P. 10% Owner Mar 06, 2013 Sale 59,915
Domain Partners VI, L.P. 10% Owner Mar 05, 2013 Sale 62,395
DOMAIN PARTERS VII L P 10% Owner Mar 05, 2013 Sale 20,235
DOMAIN PARTERS VII L P 10% Owner Mar 06, 2013 Sale 19,425
DP VI Associates, L.P. 10% Owner Mar 06, 2013 Sale 643
DP VI Associates, L.P. 10% Owner Mar 05, 2013 Sale 671
DP VII ASSOCIATES LP 10% Owner Mar 05, 2013 Sale 346
DP VII ASSOCIATES LP 10% Owner Mar 06, 2013 Sale 329
DP VII ASSOCIATES LP 10% Owner Mar 04, 2013 Sale 441
DP VII ASSOCIATES LP 10% Owner Mar 01, 2013 Sale 651
DP VI Associates, L.P. 10% Owner Mar 04, 2013 Sale 852
DP VI Associates, L.P. 10% Owner Mar 01, 2013 Sale 1,268
DOMAIN PARTERS VII L P 10% Owner Mar 01, 2013 Sale 38,251
DOMAIN PARTERS VII L P 10% Owner Mar 04, 2013 Sale 25,776
Domain Partners VI, L.P. 10% Owner Mar 04, 2013 Sale 79,484
Domain Partners VI, L.P. 10% Owner Mar 01, 2013 Sale 117,975
Domain Partners VI, L.P. 10% Owner Feb 20, 2013 Sale 30,862
DP VII ASSOCIATES LP 10% Owner Feb 20, 2013 Sale 170
DP VI Associates, L.P. 10% Owner Feb 20, 2013 Sale 331
DOMAIN PARTERS VII L P 10% Owner Feb 20, 2013 Sale 10,010
DP VII ASSOCIATES LP 10% Owner Feb 15, 2013 Sale 255
DP VII ASSOCIATES LP 10% Owner Feb 19, 2013 Sale 858
DOMAIN PARTERS VII L P 10% Owner Feb 15, 2013 Sale 14,835
DOMAIN PARTERS VII L P 10% Owner Feb 19, 2013 Sale 50,582
DP VI Associates, L.P. 10% Owner Feb 19, 2013 Sale 1,677
DP VI Associates, L.P. 10% Owner Feb 15, 2013 Sale 495
Domain Partners VI, L.P. 10% Owner Feb 19, 2013 Sale 155,996
Domain Partners VI, L.P. 10% Owner Feb 15, 2013 Sale 45,740
DP VII ASSOCIATES LP 10% Owner Feb 13, 2013 Sale 490
DP VII ASSOCIATES LP 10% Owner Feb 14, 2013 Sale 256
DP VI Associates, L.P. 10% Owner Feb 14, 2013 Sale 491
DP VI Associates, L.P. 10% Owner Feb 13, 2013 Sale 955
DOMAIN PARTERS VII L P 10% Owner Feb 13, 2013 Sale 28,815
DOMAIN PARTERS VII L P 10% Owner Feb 14, 2013 Sale 14,785
Domain Partners VI, L.P. 10% Owner Feb 13, 2013 Sale 88,850
Domain Partners VI, L.P. 10% Owner Feb 14, 2013 Sale 45,591
Domain Partners VI, L.P. 10% Owner Feb 01, 2013 Sale 146,150
DP VII ASSOCIATES LP 10% Owner Feb 01, 2013 Sale 795
DP VI Associates, L.P. 10% Owner Feb 01, 2013 Sale 1,562
DOMAIN PARTERS VII L P 10% Owner Feb 01, 2013 Sale 47,380
Domain Partners VI, L.P. 10% Owner Jan 31, 2013 Sale 269,247
Domain Partners VI, L.P. 10% Owner Jan 30, 2013 Sale 171,240
DOMAIN PARTERS VII L P 10% Owner Jan 31, 2013 Sale 87,309
DOMAIN PARTERS VII L P 10% Owner Jan 30, 2013 Sale 55,525
DP VI Associates, L.P. 10% Owner Jan 31, 2013 Sale 2,887
DP VI Associates, L.P. 10% Owner Jan 30, 2013 Sale 1,835
DP VII ASSOCIATES LP 10% Owner Jan 31, 2013 Sale 1,479
DP VII ASSOCIATES LP 10% Owner Jan 30, 2013 Sale 940
Domain Partners VI, L.P. 10% Owner Jan 29, 2013 Sale 248,992
Domain Partners VI, L.P. 10% Owner Jan 28, 2013 Sale 277,436
DOMAIN PARTERS VII L P 10% Owner Jan 29, 2013 Sale 80,736
DOMAIN PARTERS VII L P 10% Owner Jan 28, 2013 Sale 89,964
DP VII ASSOCIATES LP 10% Owner Jan 29, 2013 Sale 1,370
DP VII ASSOCIATES LP 10% Owner Jan 28, 2013 Sale 1,523
DP VI Associates, L.P. 10% Owner Jan 29, 2013 Sale 2,672
DP VI Associates, L.P. 10% Owner Jan 28, 2013 Sale 2,975
Domain Partners VI, L.P. 10% Owner Jan 25, 2013 Sale 228,785
Domain Partners VI, L.P. 10% Owner Jan 24, 2013 Sale 610,520
DP VI Associates, L.P. 10% Owner Jan 25, 2013 Sale 2,453
DP VI Associates, L.P. 10% Owner Jan 24, 2013 Sale 6,545
Domain Partners VI, L.P. 10% Owner Jan 25, 2013 Sale 228,785
Domain Partners VI, L.P. 10% Owner Jan 24, 2013 Sale 605,070
DP VII ASSOCIATES LP 10% Owner Jan 25, 2013 Sale 1,259
DP VII ASSOCIATES LP 10% Owner Jan 24, 2013 Sale 3,357
DOMAIN PARTERS VII L P 10% Owner Jan 25, 2013 Sale 74,190
DOMAIN PARTERS VII L P 10% Owner Jan 24, 2013 Sale 197,966
DP VI Associates, L.P. 10% Owner Jan 23, 2013 Sale 4,287
DP VI Associates, L.P. 10% Owner Jan 22, 2013 Sale 2,485
Domain Partners VI, L.P. 10% Owner Jan 23, 2013 Sale 399,541
Domain Partners VI, L.P. 10% Owner Jan 22, 2013 Sale 231,688
DP VII ASSOCIATES LP 10% Owner Jan 23, 2013 Sale 2,197
DP VII ASSOCIATES LP 10% Owner Jan 22, 2013 Sale 1,275
DOMAIN PARTERS VII L P 10% Owner Jan 23, 2013 Sale 129,559
DOMAIN PARTERS VII L P 10% Owner Jan 22, 2013 Sale 75,129
Domain Partners VI, L.P. 10% Owner Jan 18, 2013 Sale 305,369
Domain Partners VI, L.P. 10% Owner Jan 17, 2013 Sale 208,131
DOMAIN PARTERS VII L P 10% Owner Jan 18, 2013 Sale 99,025
DOMAIN PARTERS VII L P 10% Owner Jan 17, 2013 Sale 67,490
DP VI Associates, L.P. 10% Owner Jan 18, 2013 Sale 3,275
DP VI Associates, L.P. 10% Owner Jan 17, 2013 Sale 2,236
DP VII ASSOCIATES LP 10% Owner Jan 18, 2013 Sale 1,682
DP VII ASSOCIATES LP 10% Owner Jan 17, 2013 Sale 1,145
LARUE WILLIAM R SVP, CFO, Treas, Asst Sec Nov 21, 2011 Sale 41,632
AKER HAZEL M SVP, GC & Secretary Nov 21, 2011 Sale 41,621
Schroeder Theodore R President, CEO Nov 02, 2011 Option Exercise 41,962
BREITMEYER JAMES B EVP, CMO Nov 03, 2011 Sale 71,304
BREITMEYER JAMES B EVP, CMO Jul 11, 2011 Option Exercise 9,600
BREITMEYER JAMES B EVP, CMO Jul 11, 2011 Sale 26,970
Schroeder Theodore R President, CEO May 17, 2011 Buy 119,626
Byrd Scott A. SVP, Chief Commercial Officer May 10, 2011 Buy 14,431
BARKER SAM L Director May 10, 2011 Buy 63,330
BREITMEYER JAMES B EVP, CMO May 02, 2011 Option Exercise 38,400
BREITMEYER JAMES B EVP, CMO May 02, 2011 Sale 100,163
BREITMEYER JAMES B EVP, CMO Apr 01, 2011 Option Exercise 22,400
BREITMEYER JAMES B EVP, CMO Apr 01, 2011 Sale 64,400
BREITMEYER JAMES B EVP, CMO Mar 04, 2011 Option Exercise 22,400
BREITMEYER JAMES B EVP, CMO Mar 04, 2011 Sale 59,500
BREITMEYER JAMES B EVP, CMO Feb 03, 2011 Option Exercise 124,800
BREITMEYER JAMES B EVP, CMO Feb 03, 2011 Sale 288,015
BREITMEYER JAMES B EVP, CMO Nov 02, 2010 Option Exercise 57,600
BREITMEYER JAMES B EVP, CMO Nov 01, 2010 Option Exercise 22,400
BREITMEYER JAMES B EVP, CMO Nov 01, 2010 Sale 63,000
BREITMEYER JAMES B EVP, CMO Nov 02, 2010 Sale 162,857
BREITMEYER JAMES B EVP, CMO Oct 05, 2010 Option Exercise 22,400
BREITMEYER JAMES B EVP, CMO Oct 05, 2010 Sale 59,500
Schroeder Theodore R President, CEO Oct 01, 2010 Sale 77,670
Schroeder Theodore R President, CEO Sep 30, 2010 Sale 339,691
BREITMEYER JAMES B EVP, CMO Sep 27, 2010 Option Exercise 7,562
BREITMEYER JAMES B EVP, CMO Sep 29, 2010 Option Exercise 14,838
BREITMEYER JAMES B EVP, CMO Sep 27, 2010 Sale 20,086
BREITMEYER JAMES B EVP, CMO Sep 29, 2010 Sale 39,415