Insider Transactions for Aclaris Therapeutics, Inc. (ACRS)

Owner Relationship Date Transaction Cost # Shares Value($) Total Shares Form 4
Gordon David N. Chief Medical Officer Jul 02, 2019 Option Exercise $2.34 1,648 3,856 4,352 Jul 03, 2019, 04:44 PM
Flynn James E 10% Owner Jun 27, 2019 Sale $2.69 108,674 292,409 964,101 Jul 01, 2019, 05:01 PM
Flynn James E 10% Owner Jun 27, 2019 Sale $2.69 590,801 1,589,668 3,159,165 Jul 01, 2019, 05:01 PM
Flynn James E 10% Owner Jun 26, 2019 Sale $4.50 1,352 6,086 3,749,966 Jun 26, 2019, 05:52 PM
Flynn James E 10% Owner Jun 26, 2019 Sale $4.50 352 1,585 1,072,775 Jun 26, 2019, 05:52 PM
Flynn James E 10% Owner Jun 21, 2019 Sale $4.62 70,135 323,701 1,096,824 Jun 25, 2019, 06:31 PM
Flynn James E 10% Owner Jun 25, 2019 Sale $4.51 10,634 47,948 1,073,127 Jun 25, 2019, 06:31 PM
Flynn James E 10% Owner Jun 24, 2019 Sale $4.52 50,177 226,925 3,792,168 Jun 25, 2019, 06:31 PM
Flynn James E 10% Owner Jun 24, 2019 Sale $4.52 13,063 59,077 1,083,761 Jun 25, 2019, 06:31 PM
Flynn James E 10% Owner Jun 21, 2019 Sale $4.62 269,402 1,243,398 3,842,345 Jun 25, 2019, 06:31 PM
Flynn James E 10% Owner Jun 25, 2019 Sale $4.51 40,850 184,189 3,751,318 Jun 25, 2019, 06:31 PM
Flynn James E 10% Owner May 09, 2019 Sale $6.16 261,345 1,609,232 4,220,443 May 13, 2019, 05:24 PM
Flynn James E 10% Owner May 10, 2019 Sale $6.05 71,869 434,750 1,166,959 May 13, 2019, 05:24 PM
Flynn James E 10% Owner May 10, 2019 Sale $6.05 108,696 657,524 4,111,747 May 13, 2019, 05:24 PM
Flynn James E 10% Owner May 09, 2019 Sale $6.16 172,800 1,064,016 1,238,828 May 13, 2019, 05:24 PM
Walker Neal President and CEO Feb 01, 2019 Option Exercise $6.96 3,579 24,910 917,345 Feb 05, 2019, 06:34 PM
Powala Christopher Chief Reg & Develop Officer Feb 01, 2019 Option Exercise $6.96 1,114 7,753 141,729 Feb 05, 2019, 06:33 PM
Shanler Stuart Chief Scientific Officer Feb 01, 2019 Option Exercise $6.96 1,308 9,104 272,047 Feb 05, 2019, 06:32 PM
Ruffo Frank Chief Financial Officer Feb 01, 2019 Option Exercise $6.96 1,308 9,104 164,976 Feb 05, 2019, 06:31 PM
Fair Brett Chief Commercial Officer Feb 01, 2019 Option Exercise $6.96 1,308 9,104 10,582 Feb 05, 2019, 06:30 PM
Ali-Jackson Kamil Chief Legal Officer Feb 01, 2019 Option Exercise $6.96 1,308 9,104 82,212 Feb 05, 2019, 06:29 PM
Ruffo Frank Chief Financial Officer Dec 18, 2018 Option Exercise $6.30 356 2,243 162,409 Dec 21, 2018, 07:34 AM
Walker Neal President and CEO Dec 18, 2018 Option Exercise $6.30 833 5,248 910,124 Dec 21, 2018, 07:33 AM
Shanler Stuart Chief Scientific Officer Dec 18, 2018 Option Exercise $6.30 412 2,596 269,480 Dec 21, 2018, 07:32 AM
Fair Brett Chief Commercial Officer Dec 18, 2018 Option Exercise $6.30 498 3,137 8,015 Dec 21, 2018, 07:31 AM
Powala Christopher Chief Reg & Develop Officer Dec 18, 2018 Option Exercise $6.30 446 2,810 139,443 Dec 21, 2018, 07:29 AM
Ali-Jackson Kamil Chief Legal Officer Dec 18, 2018 Option Exercise $6.30 306 1,928 79,645 Dec 20, 2018, 09:59 PM
Walker Neal President and CEO Dec 15, 2018 Option Exercise $7.31 863 6,309 908,032 Dec 18, 2018, 08:54 PM
Ruffo Frank Chief Financial Officer Dec 15, 2018 Option Exercise $7.31 370 2,705 161,515 Dec 18, 2018, 08:54 PM
Shanler Stuart Chief Scientific Officer Dec 15, 2018 Option Exercise $7.31 370 2,705 268,442 Dec 18, 2018, 08:53 PM
Ali-Jackson Kamil Chief Legal Officer Dec 15, 2018 Option Exercise $7.31 493 3,604 78,876 Dec 18, 2018, 08:52 PM
Powala Christopher Chief Reg & Develop Officer Dec 15, 2018 Option Exercise $7.31 357 2,610 138,264 Dec 18, 2018, 08:51 PM
Fair Brett Chief Commercial Officer Dec 15, 2018 Option Exercise $7.31 288 2,105 6,763 Dec 18, 2018, 08:51 PM
Mehra Anand Director Oct 22, 2018 Buy $10.75 372,093 4,000,000 1,911,573 Oct 23, 2018, 07:13 PM
Tullman Stephen A. Director Oct 04, 2018 Buy $14.00 7,100 99,370 177,457 Oct 05, 2018, 04:37 PM
Tullman Stephen A. Director Aug 23, 2018 Buy $15.00 6,600 98,985 170,357 Aug 27, 2018, 04:46 PM
Tullman Stephen A. Director Aug 15, 2018 Buy $15.97 6,250 99,813 163,757 Aug 17, 2018, 04:55 PM
Ali-Jackson Kamil Chief Legal Officer Jun 11, 2018 Sale $20.00 100 2,000 82,536 Jun 12, 2018, 06:42 PM
Ali-Jackson Kamil Chief Legal Officer Jun 12, 2018 Sale $20.00 4,900 98,000 77,636 Jun 12, 2018, 06:42 PM
Ali-Jackson Kamil Chief Legal Officer May 18, 2018 Sale $20.00 10,000 200,000 82,636 May 21, 2018, 04:06 PM
Powell Andrew Kenneth William Director May 16, 2018 Buy $19.12 500 9,560 500 May 17, 2018, 07:34 PM
Walker Neal President and CEO May 07, 2018 Option Exercise $18.10 3,455 62,536 905,862 May 09, 2018, 04:22 PM
Shanler Stuart Chief Scientific Officer May 07, 2018 Option Exercise $18.10 1,480 26,788 267,512 May 09, 2018, 04:21 PM
Ruffo Frank Chief Financial Officer May 07, 2018 Option Exercise $18.10 1,480 26,788 160,585 May 09, 2018, 04:20 PM
Powala Christopher Chief Reg & Develop Officer May 07, 2018 Option Exercise $18.10 1,480 26,788 137,321 May 09, 2018, 04:19 PM
Fair Brett Chief Commercial Officer May 07, 2018 Option Exercise $18.10 1,153 20,869 6,038 May 09, 2018, 04:18 PM
Ali-Jackson Kamil Chief Legal Officer May 07, 2018 Option Exercise $18.10 1,974 35,729 92,636 May 09, 2018, 04:17 PM
Ruffo Frank Chief Financial Officer May 07, 2018 Buy $18.22 1,250 22,775 156,865 May 07, 2018, 04:28 PM
Ruffo Frank Chief Financial Officer Apr 06, 2018 Buy $16.59 1,250 20,738 155,615 Apr 09, 2018, 04:51 PM
Tullman Stephen A. Director Apr 06, 2018 Buy $16.54 26,700 441,618 157,507 Apr 09, 2018, 04:50 PM
Molineaux Christopher P. Director Apr 06, 2018 Sale $16.52 2,300 37,996 7,682 Apr 09, 2018, 04:50 PM
Walker Neal President and CEO Apr 05, 2018 Buy $16.75 10,000 167,500 897,184 Apr 09, 2018, 08:38 AM
Molineaux Christopher P. Director Mar 20, 2018 Option Exercise $0.55 2,377 1,305 9,982 Mar 22, 2018, 04:35 PM
Walker Neal President and CEO Dec 15, 2017 Option Exercise $24.23 922 22,340 876,130 Dec 21, 2017, 04:58 PM
Walker Neal President and CEO Dec 18, 2017 Option Exercise $24.12 889 21,443 878,166 Dec 21, 2017, 04:58 PM
Ruffo Frank Chief Financial Officer Dec 18, 2017 Option Exercise $24.12 380 9,166 145,347 Dec 21, 2017, 04:57 PM
Ruffo Frank Chief Financial Officer Dec 15, 2017 Option Exercise $24.23 395 9,571 144,477 Dec 21, 2017, 04:57 PM
Powala Christopher Chief Operating Officer Dec 15, 2017 Option Exercise $24.23 395 9,571 132,470 Dec 21, 2017, 04:57 PM
Powala Christopher Chief Operating Officer Dec 18, 2017 Option Exercise $24.12 494 11,915 133,601 Dec 21, 2017, 04:57 PM
Ali-Jackson Kamil Chief Legal Officer Dec 18, 2017 Option Exercise $24.12 327 7,887 78,659 Dec 21, 2017, 04:56 PM
Ali-Jackson Kamil Chief Legal Officer Dec 15, 2017 Option Exercise $24.23 527 12,769 77,911 Dec 21, 2017, 04:56 PM
Shanler Stuart Chief Scientific Officer Dec 15, 2017 Option Exercise $24.23 395 9,571 262,783 Dec 21, 2017, 04:55 PM
Shanler Stuart Chief Scientific Officer Dec 18, 2017 Option Exercise $24.12 441 10,637 263,792 Dec 21, 2017, 04:55 PM
SCHIFF ANDREW N Director Aug 16, 2017 Buy $23.02 108,601 2,499,995 634,455 Aug 16, 2017, 04:45 PM
Molineaux Christopher P. Director Mar 17, 2017 Option Exercise $0.51 7,605 3,872 7,605 Mar 21, 2017, 08:43 PM
VIVO VENTURES VII, LLC 10% Owner Feb 28, 2017 Sale $30.50 195,734 5,969,887 3,017,798 Mar 02, 2017, 08:44 PM
VIVO VENTURES VII, LLC 10% Owner Mar 02, 2017 Sale $31.20 122,334 3,816,821 2,797,597 Mar 02, 2017, 08:44 PM
VIVO VENTURES VII, LLC 10% Owner Mar 01, 2017 Sale $30.98 2,133 66,080 63,638 Mar 02, 2017, 08:44 PM
VIVO VENTURES VII, LLC 10% Owner Mar 01, 2017 Sale $30.98 97,867 3,031,920 2,919,931 Mar 02, 2017, 08:44 PM
VIVO VENTURES VII, LLC 10% Owner Feb 28, 2017 Sale $30.50 4,266 130,113 65,771 Mar 02, 2017, 08:44 PM
VIVO VENTURES VII, LLC 10% Owner Mar 02, 2017 Sale $31.20 2,666 83,179 60,972 Mar 02, 2017, 08:44 PM
Mehra Anand Director Jan 10, 2017 Sale $28.25 750,000 21,188,325 1,539,480 Jan 12, 2017, 05:50 PM
Powala Christopher Chief Operating Officer Dec 18, 2016 Option Exercise $31.25 494 15,438 131,565 Dec 20, 2016, 06:51 PM
Ruffo Frank Chief Financial Officer Dec 18, 2016 Option Exercise $31.25 380 11,875 143,572 Dec 20, 2016, 06:51 PM
Ali-Jackson Kamil Chief Legal Officer Dec 18, 2016 Option Exercise $31.25 327 10,219 76,705 Dec 20, 2016, 06:50 PM
Walker Neal President and CEO Dec 18, 2016 Option Exercise $31.25 889 27,781 874,019 Dec 20, 2016, 06:49 PM
Shanler Stuart Chief Scientific Officer Dec 18, 2016 Option Exercise $31.25 441 13,781 261,878 Dec 20, 2016, 06:49 PM
VIVO VENTURES VII, LLC 10% Owner Nov 18, 2016 Sale $22.72 440,402 10,005,933 3,213,532 Nov 18, 2016, 07:44 PM
VIVO VENTURES VII, LLC 10% Owner Nov 16, 2016 Sale $27.30 9,765 266,584 79,635 Nov 18, 2016, 07:44 PM
VIVO VENTURES VII, LLC 10% Owner Nov 16, 2016 Sale $23.25 448,063 10,417,465 3,653,934 Nov 18, 2016, 07:44 PM
VIVO VENTURES VII, LLC 10% Owner Nov 18, 2016 Sale $22.72 9,598 218,067 70,037 Nov 18, 2016, 07:44 PM
Ali-Jackson Kamil Chief Legal Officer Oct 26, 2016 Option Exercise $1.52 3,912 5,946 79,869 Oct 28, 2016, 04:10 PM
Ali-Jackson Kamil Chief Legal Officer Oct 26, 2016 Sale $21.83 3,912 85,399 75,957 Oct 28, 2016, 04:10 PM
FMR LLC 10% Owner Oct 26, 2016 Sale $21.94 3,750 82,260 2,571,454 Oct 28, 2016, 03:39 PM
Ali-Jackson Kamil Chief Legal Officer Sep 28, 2016 Option Exercise $0.72 1,841 1,326 77,798 Sep 28, 2016, 06:10 PM
Ali-Jackson Kamil Chief Legal Officer Sep 28, 2016 Sale $24.66 1,841 45,399 75,957 Sep 28, 2016, 06:10 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Sep 16, 2016 Sale $24.51 173,600 4,254,212 2,125,769 Sep 19, 2016, 05:15 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Sep 15, 2016 Sale $24.04 351,950 8,459,290 2,607,719 Sep 19, 2016, 05:15 PM
Ali-Jackson Kamil Chief Legal Officer Aug 26, 2016 Sale $20.35 3,738 76,068 20,289 Aug 29, 2016, 04:15 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Feb 22, 2016 Buy $15.99 11,318 180,958 2,599,311 Feb 24, 2016, 04:56 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Feb 23, 2016 Buy $17.62 28,408 500,512 2,627,719 Feb 24, 2016, 04:56 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Jan 20, 2016 Buy $19.88 1,803 35,849 2,587,993 Jan 20, 2016, 04:51 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Jan 19, 2016 Buy $19.88 4,200 83,480 2,586,190 Jan 20, 2016, 04:51 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Jan 15, 2016 Buy $19.86 1,800 35,743 2,581,990 Jan 20, 2016, 04:51 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Jan 13, 2016 Buy $19.97 5,543 110,674 2,580,190 Jan 13, 2016, 04:39 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Jan 12, 2016 Buy $19.12 5,941 113,585 2,574,647 Jan 13, 2016, 04:39 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Jan 11, 2016 Buy $17.93 4,153 74,479 2,568,706 Jan 13, 2016, 04:39 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 28, 2015 Buy $14.00 149,200 2,088,800 2,469,552 Oct 30, 2015, 03:53 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 29, 2015 Buy $14.00 95,000 1,330,000 2,564,552 Oct 30, 2015, 03:53 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 22, 2015 Buy $14.03 5,410 75,883 2,320,352 Oct 26, 2015, 04:17 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 19, 2015 Buy $14.88 23,934 356,049 2,303,877 Oct 21, 2015, 04:35 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 21, 2015 Buy $14.83 3,100 45,976 2,314,942 Oct 21, 2015, 04:35 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 20, 2015 Buy $14.95 7,965 119,070 2,311,842 Oct 21, 2015, 04:35 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 14, 2015 Buy $14.06 42,813 601,792 2,279,943 Oct 16, 2015, 04:17 PM
FMR LLC 10% Owner Oct 13, 2015 Buy $11.00 335,455 3,690,005 3,804,279 Oct 14, 2015, 02:40 PM
CHA ALBERT Director Oct 13, 2015 Buy $11.00 454,545 4,999,995 4,191,397 Oct 13, 2015, 01:30 PM
VIVO VENTURES VII, LLC 10% Owner Oct 13, 2015 Buy $11.00 9,695 106,645 89,400 Oct 13, 2015, 01:29 PM
VIVO VENTURES VII, LLC 10% Owner Oct 13, 2015 Buy $11.00 444,850 4,893,350 4,101,997 Oct 13, 2015, 01:29 PM
Mehra Anand Director Oct 13, 2015 Buy $11.00 409,090 4,499,990 2,289,480 Oct 13, 2015, 01:26 PM
Sofinnova Venture Partners VIII, L.P. 10% Owner Oct 13, 2015 Buy $11.00 409,090 4,499,990 2,289,480 Oct 13, 2015, 01:26 PM
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 07, 2015 Buy $10.86 2,215,439 24,051,364 2,215,439 Oct 13, 2015, 09:34 AM
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 08, 2015 Buy $11.00 21,691 238,555 2,237,130 Oct 13, 2015, 09:34 AM
VIVO VENTURES VII, LLC 10% Owner Oct 07, 2015 Buy $11.00 285 3,135 6,467 Oct 09, 2015, 04:05 PM
VIVO VENTURES VII, LLC 10% Owner Oct 07, 2015 Buy $11.00 13,067 143,737 296,739 Oct 09, 2015, 04:05 PM
CHA ALBERT Director Oct 07, 2015 Buy $11.00 13,352 146,872 303,206 Oct 09, 2015, 04:03 PM

Desktop Version

Owner Relationship Date Transaction Value($)
Gordon David N. Chief Medical Officer Jul 02, 2019 Option Exercise 3,856
Flynn James E 10% Owner Jun 27, 2019 Sale 292,409
Flynn James E 10% Owner Jun 27, 2019 Sale 1,589,668
Flynn James E 10% Owner Jun 26, 2019 Sale 6,086
Flynn James E 10% Owner Jun 26, 2019 Sale 1,585
Flynn James E 10% Owner Jun 21, 2019 Sale 323,701
Flynn James E 10% Owner Jun 25, 2019 Sale 47,948
Flynn James E 10% Owner Jun 24, 2019 Sale 226,925
Flynn James E 10% Owner Jun 24, 2019 Sale 59,077
Flynn James E 10% Owner Jun 21, 2019 Sale 1,243,398
Flynn James E 10% Owner Jun 25, 2019 Sale 184,189
Flynn James E 10% Owner May 09, 2019 Sale 1,609,232
Flynn James E 10% Owner May 10, 2019 Sale 434,750
Flynn James E 10% Owner May 10, 2019 Sale 657,524
Flynn James E 10% Owner May 09, 2019 Sale 1,064,016
Walker Neal President and CEO Feb 01, 2019 Option Exercise 24,910
Powala Christopher Chief Reg & Develop Officer Feb 01, 2019 Option Exercise 7,753
Shanler Stuart Chief Scientific Officer Feb 01, 2019 Option Exercise 9,104
Ruffo Frank Chief Financial Officer Feb 01, 2019 Option Exercise 9,104
Fair Brett Chief Commercial Officer Feb 01, 2019 Option Exercise 9,104
Ali-Jackson Kamil Chief Legal Officer Feb 01, 2019 Option Exercise 9,104
Ruffo Frank Chief Financial Officer Dec 18, 2018 Option Exercise 2,243
Walker Neal President and CEO Dec 18, 2018 Option Exercise 5,248
Shanler Stuart Chief Scientific Officer Dec 18, 2018 Option Exercise 2,596
Fair Brett Chief Commercial Officer Dec 18, 2018 Option Exercise 3,137
Powala Christopher Chief Reg & Develop Officer Dec 18, 2018 Option Exercise 2,810
Ali-Jackson Kamil Chief Legal Officer Dec 18, 2018 Option Exercise 1,928
Walker Neal President and CEO Dec 15, 2018 Option Exercise 6,309
Ruffo Frank Chief Financial Officer Dec 15, 2018 Option Exercise 2,705
Shanler Stuart Chief Scientific Officer Dec 15, 2018 Option Exercise 2,705
Ali-Jackson Kamil Chief Legal Officer Dec 15, 2018 Option Exercise 3,604
Powala Christopher Chief Reg & Develop Officer Dec 15, 2018 Option Exercise 2,610
Fair Brett Chief Commercial Officer Dec 15, 2018 Option Exercise 2,105
Mehra Anand Director Oct 22, 2018 Buy 4,000,000
Tullman Stephen A. Director Oct 04, 2018 Buy 99,370
Tullman Stephen A. Director Aug 23, 2018 Buy 98,985
Tullman Stephen A. Director Aug 15, 2018 Buy 99,813
Ali-Jackson Kamil Chief Legal Officer Jun 11, 2018 Sale 2,000
Ali-Jackson Kamil Chief Legal Officer Jun 12, 2018 Sale 98,000
Ali-Jackson Kamil Chief Legal Officer May 18, 2018 Sale 200,000
Powell Andrew Kenneth William Director May 16, 2018 Buy 9,560
Walker Neal President and CEO May 07, 2018 Option Exercise 62,536
Shanler Stuart Chief Scientific Officer May 07, 2018 Option Exercise 26,788
Ruffo Frank Chief Financial Officer May 07, 2018 Option Exercise 26,788
Powala Christopher Chief Reg & Develop Officer May 07, 2018 Option Exercise 26,788
Fair Brett Chief Commercial Officer May 07, 2018 Option Exercise 20,869
Ali-Jackson Kamil Chief Legal Officer May 07, 2018 Option Exercise 35,729
Ruffo Frank Chief Financial Officer May 07, 2018 Buy 22,775
Ruffo Frank Chief Financial Officer Apr 06, 2018 Buy 20,738
Tullman Stephen A. Director Apr 06, 2018 Buy 441,618
Molineaux Christopher P. Director Apr 06, 2018 Sale 37,996
Walker Neal President and CEO Apr 05, 2018 Buy 167,500
Molineaux Christopher P. Director Mar 20, 2018 Option Exercise 1,305
Walker Neal President and CEO Dec 15, 2017 Option Exercise 22,340
Walker Neal President and CEO Dec 18, 2017 Option Exercise 21,443
Ruffo Frank Chief Financial Officer Dec 18, 2017 Option Exercise 9,166
Ruffo Frank Chief Financial Officer Dec 15, 2017 Option Exercise 9,571
Powala Christopher Chief Operating Officer Dec 15, 2017 Option Exercise 9,571
Powala Christopher Chief Operating Officer Dec 18, 2017 Option Exercise 11,915
Ali-Jackson Kamil Chief Legal Officer Dec 18, 2017 Option Exercise 7,887
Ali-Jackson Kamil Chief Legal Officer Dec 15, 2017 Option Exercise 12,769
Shanler Stuart Chief Scientific Officer Dec 15, 2017 Option Exercise 9,571
Shanler Stuart Chief Scientific Officer Dec 18, 2017 Option Exercise 10,637
SCHIFF ANDREW N Director Aug 16, 2017 Buy 2,499,995
Molineaux Christopher P. Director Mar 17, 2017 Option Exercise 3,872
VIVO VENTURES VII, LLC 10% Owner Feb 28, 2017 Sale 5,969,887
VIVO VENTURES VII, LLC 10% Owner Mar 02, 2017 Sale 3,816,821
VIVO VENTURES VII, LLC 10% Owner Mar 01, 2017 Sale 66,080
VIVO VENTURES VII, LLC 10% Owner Mar 01, 2017 Sale 3,031,920
VIVO VENTURES VII, LLC 10% Owner Feb 28, 2017 Sale 130,113
VIVO VENTURES VII, LLC 10% Owner Mar 02, 2017 Sale 83,179
Mehra Anand Director Jan 10, 2017 Sale 21,188,325
Powala Christopher Chief Operating Officer Dec 18, 2016 Option Exercise 15,438
Ruffo Frank Chief Financial Officer Dec 18, 2016 Option Exercise 11,875
Ali-Jackson Kamil Chief Legal Officer Dec 18, 2016 Option Exercise 10,219
Walker Neal President and CEO Dec 18, 2016 Option Exercise 27,781
Shanler Stuart Chief Scientific Officer Dec 18, 2016 Option Exercise 13,781
VIVO VENTURES VII, LLC 10% Owner Nov 18, 2016 Sale 10,005,933
VIVO VENTURES VII, LLC 10% Owner Nov 16, 2016 Sale 266,584
VIVO VENTURES VII, LLC 10% Owner Nov 16, 2016 Sale 10,417,465
VIVO VENTURES VII, LLC 10% Owner Nov 18, 2016 Sale 218,067
Ali-Jackson Kamil Chief Legal Officer Oct 26, 2016 Option Exercise 5,946
Ali-Jackson Kamil Chief Legal Officer Oct 26, 2016 Sale 85,399
FMR LLC 10% Owner Oct 26, 2016 Sale 82,260
Ali-Jackson Kamil Chief Legal Officer Sep 28, 2016 Option Exercise 1,326
Ali-Jackson Kamil Chief Legal Officer Sep 28, 2016 Sale 45,399
RA CAPITAL MANAGEMENT, LLC 10% Owner Sep 16, 2016 Sale 4,254,212
RA CAPITAL MANAGEMENT, LLC 10% Owner Sep 15, 2016 Sale 8,459,290
Ali-Jackson Kamil Chief Legal Officer Aug 26, 2016 Sale 76,068
RA CAPITAL MANAGEMENT, LLC 10% Owner Feb 22, 2016 Buy 180,958
RA CAPITAL MANAGEMENT, LLC 10% Owner Feb 23, 2016 Buy 500,512
RA CAPITAL MANAGEMENT, LLC 10% Owner Jan 20, 2016 Buy 35,849
RA CAPITAL MANAGEMENT, LLC 10% Owner Jan 19, 2016 Buy 83,480
RA CAPITAL MANAGEMENT, LLC 10% Owner Jan 15, 2016 Buy 35,743
RA CAPITAL MANAGEMENT, LLC 10% Owner Jan 13, 2016 Buy 110,674
RA CAPITAL MANAGEMENT, LLC 10% Owner Jan 12, 2016 Buy 113,585
RA CAPITAL MANAGEMENT, LLC 10% Owner Jan 11, 2016 Buy 74,479
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 28, 2015 Buy 2,088,800
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 29, 2015 Buy 1,330,000
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 22, 2015 Buy 75,883
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 19, 2015 Buy 356,049
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 21, 2015 Buy 45,976
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 20, 2015 Buy 119,070
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 14, 2015 Buy 601,792
FMR LLC 10% Owner Oct 13, 2015 Buy 3,690,005
CHA ALBERT Director Oct 13, 2015 Buy 4,999,995
VIVO VENTURES VII, LLC 10% Owner Oct 13, 2015 Buy 106,645
VIVO VENTURES VII, LLC 10% Owner Oct 13, 2015 Buy 4,893,350
Mehra Anand Director Oct 13, 2015 Buy 4,499,990
Sofinnova Venture Partners VIII, L.P. 10% Owner Oct 13, 2015 Buy 4,499,990
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 07, 2015 Buy 24,051,364
RA CAPITAL MANAGEMENT, LLC 10% Owner Oct 08, 2015 Buy 238,555
VIVO VENTURES VII, LLC 10% Owner Oct 07, 2015 Buy 3,135
VIVO VENTURES VII, LLC 10% Owner Oct 07, 2015 Buy 143,737
CHA ALBERT Director Oct 07, 2015 Buy 146,872