| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| CYTH | Chief Scientific Officer | Dec 02, 2021 | Buy | $4.98 | 1,000 | 4,980 | 19,350 | Dec 02, 2021, 04:54 PM |
| CYTH | Chief Scientific Officer | Mar 29, 2021 | Buy | $7.46 | 1,000 | 7,460 | 18,350 | Mar 30, 2021, 01:25 PM |
| CTDH | Chief Scientific Officer | Apr 24, 2020 | Option Exercise | $0.10 | 200,000 | 20,000 | 635,000 | Apr 27, 2020, 04:06 PM |
| CTDH | Chief Scientific Officer | Aug 01, 2019 | Buy | $0.25 | 10,000 | 2,475 | 335,000 | Aug 02, 2019, 11:52 AM |
| CTDH | Chief Scientific Officer | Jul 31, 2019 | Buy | $0.24 | 10,000 | 2,425 | 325,000 | Jul 31, 2019, 06:30 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| CYTH | Chief Scientific Officer | Dec 02, 2021 | Buy | 4,980 |
| CYTH | Chief Scientific Officer | Mar 29, 2021 | Buy | 7,460 |
| CTDH | Chief Scientific Officer | Apr 24, 2020 | Option Exercise | 20,000 |
| CTDH | Chief Scientific Officer | Aug 01, 2019 | Buy | 2,475 |
| CTDH | Chief Scientific Officer | Jul 31, 2019 | Buy | 2,425 |