| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| CARA | Chief Scientific Off,SVP-R&D | Apr 01, 2022 | Sale | $11.91 | 1,784 | 21,247 | 169,781 | Apr 05, 2022, 05:49 PM |
| CARA | Chief Scientific Off,SVP-R&D | Aug 30, 2021 | Sale | $14.20 | 3,847 | 54,627 | 141,072 | Sep 01, 2021, 06:07 PM |
| CARA | Chief Scientific Off,SVP-R&D | Mar 05, 2021 | Sale | $17.98 | 3,358 | 60,377 | 119,319 | Mar 08, 2021, 05:48 PM |
| CARA | Chief Scientific Off,SVP-R&D | Feb 25, 2021 | Sale | $19.33 | 5,003 | 96,708 | 112,677 | Feb 25, 2021, 09:05 PM |
| CARA | Chief Scientific Off,SVP-R&D | Dec 30, 2020 | Sale | $15.30 | 2,812 | 43,024 | 109,680 | Dec 30, 2020, 06:15 PM |
| CARA | Chief Scientific Off,SVP-R&D | Apr 21, 2020 | Sale | $15.58 | 12,894 | 200,889 | 104,492 | Apr 21, 2020, 06:49 PM |
| CARA | Chief Scientific Off,SVP-R&D | Oct 25, 2019 | Sale | $19.91 | 4,000 | 79,640 | 63,886 | Oct 29, 2019, 08:36 PM |
| CARA | Chief Scientific Off,SVP-R&D | Oct 18, 2019 | Sale | $19.33 | 4,000 | 77,320 | 67,886 | Oct 22, 2019, 05:01 PM |
| CARA | Chief Scientific Off,SVP-R&D | Oct 11, 2019 | Sale | $18.70 | 4,000 | 74,800 | 71,886 | Oct 16, 2019, 06:26 PM |
| CARA | Chief Scientific Off,SVP-R&D | Oct 04, 2019 | Sale | $19.19 | 4,000 | 76,760 | 75,886 | Oct 08, 2019, 04:44 PM |
| CARA | Chief Scientific Off,SVP-R&D | Sep 03, 2019 | Sale | $22.92 | 20,000 | 458,400 | 79,886 | Sep 05, 2019, 05:38 PM |
| CARA | Chief Scientific Off,SVP-R&D | Aug 01, 2019 | Sale | $23.24 | 20,000 | 464,800 | 99,886 | Aug 05, 2019, 05:33 PM |
| CARA | Chief Scientific Off,SVP-R&D | Jul 17, 2019 | Sale | $27.50 | 8,996 | 247,390 | 119,886 | Jul 19, 2019, 05:47 PM |
| CARA | Chief Scientific Off,SVP-R&D | Jul 01, 2019 | Sale | $21.90 | 20,000 | 438,000 | 128,882 | Jul 03, 2019, 03:59 PM |
| CARA | Chief Scientific Off,SVP-R&D | May 29, 2019 | Sale | $21.19 | 11,397 | 241,502 | 148,882 | May 30, 2019, 06:16 PM |
| CARA | Chief Scientific Off,SVP-R&D | Mar 13, 2019 | Sale | $18.87 | 16,803 | 317,073 | 122,779 | Mar 14, 2019, 05:13 PM |
| CARA | Chief Scientific Off,SVP-R&D | Mar 12, 2019 | Sale | $17.50 | 3,197 | 55,948 | 139,582 | Mar 14, 2019, 05:13 PM |
| CARA | Sr VP-Research & Development | Feb 28, 2019 | Sale | $17.50 | 1,500 | 26,250 | 142,779 | Mar 04, 2019, 05:49 PM |
| CARA | Sr VP-Research & Development | Feb 25, 2019 | Sale | $17.50 | 2,200 | 38,500 | 144,279 | Feb 27, 2019, 05:29 PM |
| CARA | Sr VP-Research & Development | Dec 28, 2018 | Sale | $12.53 | 4,300 | 53,879 | 146,479 | Jan 02, 2019, 05:56 PM |
| CARA | Sr VP-Research & Development | Dec 03, 2018 | Sale | $18.36 | 3,000 | 55,080 | 139,000 | Dec 06, 2018, 04:18 PM |
| CARA | Sr VP-Research & Development | Nov 01, 2018 | Option Exercise | $2.05 | 40,000 | 82,000 | 145,000 | Nov 05, 2018, 08:25 PM |
| CARA | Sr VP-Research & Development | Nov 01, 2018 | Sale | $18.77 | 3,000 | 56,310 | 142,000 | Nov 05, 2018, 08:25 PM |
| CARA | Sr VP-Research & Development | Aug 06, 2018 | Option Exercise | $2.25 | 10,000 | 22,500 | 114,000 | Nov 05, 2018, 08:21 PM |
| CARA | Sr VP-Research & Development | Oct 01, 2018 | Sale | $23.99 | 3,000 | 71,970 | 95,000 | Oct 03, 2018, 04:09 PM |
| CARA | Sr VP-Research & Development | Sep 04, 2018 | Sale | $19.81 | 3,000 | 59,430 | 98,000 | Sep 06, 2018, 05:33 PM |
| CARA | Sr VP-Research & Development | Aug 20, 2018 | Sale | $18.89 | 3,000 | 56,670 | 101,000 | Aug 22, 2018, 05:26 PM |
| CARA | Sr VP-Research & Development | Jul 02, 2018 | Sale | $19.00 | 3,000 | 57,000 | 104,000 | Jul 05, 2018, 05:00 PM |
| CARA | Sr VP-Research & Development | Jun 01, 2018 | Sale | $15.49 | 3,000 | 46,470 | 107,000 | Jun 05, 2018, 07:15 PM |
| CARA | Sr VP-Research & Development | May 23, 2018 | Sale | $15.19 | 9,000 | 136,710 | 110,000 | May 25, 2018, 04:22 PM |
| CARA | Sr VP-Research & Development | Feb 15, 2018 | Sale | $15.02 | 3,000 | 45,060 | 119,000 | Feb 20, 2018, 04:43 PM |
| CARA | Sr VP-Research & Development | Jan 24, 2018 | Sale | $15.00 | 15,000 | 225,000 | 122,000 | Jan 26, 2018, 05:53 PM |
| CARA | Sr VP-Research & Development | Nov 07, 2017 | Option Exercise | $2.48 | 20,000 | 49,600 | 137,000 | Nov 09, 2017, 04:36 PM |
| CARA | VP-Research & Development | Aug 04, 2017 | Sale | $15.00 | 3,000 | 45,000 | 117,000 | Aug 10, 2017, 05:47 PM |
| CARA | VP-Research & Development | Jul 14, 2017 | Sale | $15.00 | 3,000 | 45,000 | 120,000 | Jul 18, 2017, 06:09 PM |
| CARA | VP-Research & Development | Apr 20, 2016 | Sale | $9.00 | 6,000 | 54,000 | 123,000 | Apr 20, 2016, 05:34 PM |
| CARA | VP-Research & Development | Feb 03, 2016 | Sale | $9.00 | 1,000 | 9,000 | 129,000 | Feb 03, 2016, 04:41 PM |
| CARA | VP-Research & Development | Feb 01, 2016 | Sale | $9.05 | 5,000 | 45,250 | 130,000 | Feb 03, 2016, 04:41 PM |
| CARA | VP-Research & Development | Jan 04, 2016 | Sale | $16.80 | 6,000 | 100,800 | 135,000 | Jan 05, 2016, 04:56 PM |
| CARA | VP-Research & Development | Dec 01, 2015 | Sale | $16.21 | 6,000 | 97,260 | 141,000 | Dec 03, 2015, 05:17 PM |
| CARA | VP-Research & Development | Nov 02, 2015 | Sale | $14.26 | 6,000 | 85,560 | 147,000 | Nov 03, 2015, 06:08 PM |
| CARA | VP-Research & Development | Oct 01, 2015 | Sale | $13.95 | 6,000 | 83,715 | 154,500 | Oct 05, 2015, 04:57 PM |
| CARA | VP-Research & Development | Sep 01, 2015 | Sale | $18.63 | 7,000 | 130,410 | 159,000 | Sep 03, 2015, 05:52 PM |
| CARA | VP-Research & Development | Aug 03, 2015 | Sale | $21.41 | 7,000 | 149,870 | 166,000 | Aug 05, 2015, 05:16 PM |
| CARA | VP-Research & Development | Jul 01, 2015 | Sale | $12.22 | 7,000 | 85,540 | 173,000 | Jul 06, 2015, 05:06 PM |
| CARA | VP-Research & Development | Mar 09, 2015 | Option Exercise | $0.25 | 20,000 | 5,000 | 180,000 | Mar 11, 2015, 04:54 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| CARA | Chief Scientific Off,SVP-R&D | Apr 01, 2022 | Sale | 21,247 |
| CARA | Chief Scientific Off,SVP-R&D | Aug 30, 2021 | Sale | 54,627 |
| CARA | Chief Scientific Off,SVP-R&D | Mar 05, 2021 | Sale | 60,377 |
| CARA | Chief Scientific Off,SVP-R&D | Feb 25, 2021 | Sale | 96,708 |
| CARA | Chief Scientific Off,SVP-R&D | Dec 30, 2020 | Sale | 43,024 |
| CARA | Chief Scientific Off,SVP-R&D | Apr 21, 2020 | Sale | 200,889 |
| CARA | Chief Scientific Off,SVP-R&D | Oct 25, 2019 | Sale | 79,640 |
| CARA | Chief Scientific Off,SVP-R&D | Oct 18, 2019 | Sale | 77,320 |
| CARA | Chief Scientific Off,SVP-R&D | Oct 11, 2019 | Sale | 74,800 |
| CARA | Chief Scientific Off,SVP-R&D | Oct 04, 2019 | Sale | 76,760 |
| CARA | Chief Scientific Off,SVP-R&D | Sep 03, 2019 | Sale | 458,400 |
| CARA | Chief Scientific Off,SVP-R&D | Aug 01, 2019 | Sale | 464,800 |
| CARA | Chief Scientific Off,SVP-R&D | Jul 17, 2019 | Sale | 247,390 |
| CARA | Chief Scientific Off,SVP-R&D | Jul 01, 2019 | Sale | 438,000 |
| CARA | Chief Scientific Off,SVP-R&D | May 29, 2019 | Sale | 241,502 |
| CARA | Chief Scientific Off,SVP-R&D | Mar 13, 2019 | Sale | 317,073 |
| CARA | Chief Scientific Off,SVP-R&D | Mar 12, 2019 | Sale | 55,948 |
| CARA | Sr VP-Research & Development | Feb 28, 2019 | Sale | 26,250 |
| CARA | Sr VP-Research & Development | Feb 25, 2019 | Sale | 38,500 |
| CARA | Sr VP-Research & Development | Dec 28, 2018 | Sale | 53,879 |
| CARA | Sr VP-Research & Development | Dec 03, 2018 | Sale | 55,080 |
| CARA | Sr VP-Research & Development | Nov 01, 2018 | Option Exercise | 82,000 |
| CARA | Sr VP-Research & Development | Nov 01, 2018 | Sale | 56,310 |
| CARA | Sr VP-Research & Development | Aug 06, 2018 | Option Exercise | 22,500 |
| CARA | Sr VP-Research & Development | Oct 01, 2018 | Sale | 71,970 |
| CARA | Sr VP-Research & Development | Sep 04, 2018 | Sale | 59,430 |
| CARA | Sr VP-Research & Development | Aug 20, 2018 | Sale | 56,670 |
| CARA | Sr VP-Research & Development | Jul 02, 2018 | Sale | 57,000 |
| CARA | Sr VP-Research & Development | Jun 01, 2018 | Sale | 46,470 |
| CARA | Sr VP-Research & Development | May 23, 2018 | Sale | 136,710 |
| CARA | Sr VP-Research & Development | Feb 15, 2018 | Sale | 45,060 |
| CARA | Sr VP-Research & Development | Jan 24, 2018 | Sale | 225,000 |
| CARA | Sr VP-Research & Development | Nov 07, 2017 | Option Exercise | 49,600 |
| CARA | VP-Research & Development | Aug 04, 2017 | Sale | 45,000 |
| CARA | VP-Research & Development | Jul 14, 2017 | Sale | 45,000 |
| CARA | VP-Research & Development | Apr 20, 2016 | Sale | 54,000 |
| CARA | VP-Research & Development | Feb 03, 2016 | Sale | 9,000 |
| CARA | VP-Research & Development | Feb 01, 2016 | Sale | 45,250 |
| CARA | VP-Research & Development | Jan 04, 2016 | Sale | 100,800 |
| CARA | VP-Research & Development | Dec 01, 2015 | Sale | 97,260 |
| CARA | VP-Research & Development | Nov 02, 2015 | Sale | 85,560 |
| CARA | VP-Research & Development | Oct 01, 2015 | Sale | 83,715 |
| CARA | VP-Research & Development | Sep 01, 2015 | Sale | 130,410 |
| CARA | VP-Research & Development | Aug 03, 2015 | Sale | 149,870 |
| CARA | VP-Research & Development | Jul 01, 2015 | Sale | 85,540 |
| CARA | VP-Research & Development | Mar 09, 2015 | Option Exercise | 5,000 |