| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| CLDN | Chief Executive Officer | Apr 06, 2015 | Option Exercise | $2.07 | 47,931 | 99,290 | 51,056 | Apr 07, 2015, 04:38 PM |
| CLDN | Chief Executive Officer | Apr 06, 2015 | Sale | $18.20 | 47,931 | 872,283 | 9,754 | Apr 07, 2015, 04:38 PM |
| CLDN | Chief Executive Officer | Mar 09, 2015 | Option Exercise | $2.07 | 47,931 | 99,290 | 51,056 | Mar 09, 2015, 09:03 PM |
| CLDN | Chief Executive Officer | Mar 09, 2015 | Sale | $24.80 | 47,931 | 1,188,505 | 9,754 | Mar 09, 2015, 09:03 PM |
| CLDN | Chief Executive Officer | Feb 09, 2015 | Option Exercise | $2.07 | 47,931 | 99,290 | 51,056 | Feb 10, 2015, 06:15 PM |
| CLDN | Chief Executive Officer | Feb 09, 2015 | Sale | $15.86 | 47,931 | 760,303 | 9,754 | Feb 10, 2015, 06:15 PM |
| CLDN | Chief Executive Officer | Jan 06, 2015 | Option Exercise | $1.12 | 41,302 | 46,258 | 44,427 | Jan 08, 2015, 06:43 PM |
| CLDN | Chief Executive Officer | Jan 06, 2015 | Sale | $17.51 | 41,302 | 723,198 | 3,125 | Jan 08, 2015, 06:43 PM |
| CLDN | Chief Executive Officer | Dec 09, 2014 | Option Exercise | $1.12 | 41,302 | 46,258 | 42,833 | Dec 10, 2014, 07:07 PM |
| CLDN | Chief Executive Officer | Dec 09, 2014 | Sale | $15.00 | 41,302 | 619,530 | 1,531 | Dec 10, 2014, 07:07 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| CLDN | Chief Executive Officer | Apr 06, 2015 | Option Exercise | 99,290 |
| CLDN | Chief Executive Officer | Apr 06, 2015 | Sale | 872,283 |
| CLDN | Chief Executive Officer | Mar 09, 2015 | Option Exercise | 99,290 |
| CLDN | Chief Executive Officer | Mar 09, 2015 | Sale | 1,188,505 |
| CLDN | Chief Executive Officer | Feb 09, 2015 | Option Exercise | 99,290 |
| CLDN | Chief Executive Officer | Feb 09, 2015 | Sale | 760,303 |
| CLDN | Chief Executive Officer | Jan 06, 2015 | Option Exercise | 46,258 |
| CLDN | Chief Executive Officer | Jan 06, 2015 | Sale | 723,198 |
| CLDN | Chief Executive Officer | Dec 09, 2014 | Option Exercise | 46,258 |
| CLDN | Chief Executive Officer | Dec 09, 2014 | Sale | 619,530 |