| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| ARNI | VP & Chief Medical Officer | Jan 12, 2016 | Buy | $0.35 | 144,806 | 50,682 | 261,832 | Jan 14, 2016, 05:20 PM |
| ARNI | VP & Chief Medical Officer | Oct 29, 2013 | Option Exercise | $2.40 | 5,000 | 12,000 | 75,360 | Oct 31, 2013, 07:53 PM |
| ARNI | VP & Chief Medical Officer | Oct 29, 2013 | Option Exercise | $2.40 | 66,652 | 159,965 | 70,360 | Oct 31, 2013, 07:53 PM |
| ARNI | VP & Chief Medical Officer | May 28, 2013 | Option Exercise | $0.30 | 9,667 | 2,900 | 29,667 | May 30, 2013, 05:05 PM |
| ARNI | VP & Chief Medical Officer | Apr 29, 2013 | Option Exercise | $0.30 | 10,000 | 3,000 | 20,000 | May 07, 2013, 09:15 AM |
| ARNI | VP & Chief Medical Officer | Mar 27, 2013 | Option Exercise | $0.30 | 10,000 | 3,000 | 10,000 | Apr 11, 2013, 02:01 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| ARNI | VP & Chief Medical Officer | Jan 12, 2016 | Buy | 50,682 |
| ARNI | VP & Chief Medical Officer | Oct 29, 2013 | Option Exercise | 12,000 |
| ARNI | VP & Chief Medical Officer | Oct 29, 2013 | Option Exercise | 159,965 |
| ARNI | VP & Chief Medical Officer | May 28, 2013 | Option Exercise | 2,900 |
| ARNI | VP & Chief Medical Officer | Apr 29, 2013 | Option Exercise | 3,000 |
| ARNI | VP & Chief Medical Officer | Mar 27, 2013 | Option Exercise | 3,000 |