| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| ALRN | SVP, Chief Medical Officer | Aug 16, 2019 | Buy | $0.59 | 75,000 | 44,453 | 75,000 | Aug 20, 2019, 04:17 PM |
| SNTA | SVP, Chief Medical Officer | Jun 05, 2013 | Buy | $4.58 | 10,000 | 45,800 | 35,249 | Jun 06, 2013, 05:04 PM |
| SNTA | SVP, Chief Medical Officer | Jun 29, 2012 | Buy | $5.59 | 3,000 | 16,755 | 25,249 | Jul 02, 2012, 08:53 AM |
| SNTA | SVP, Chief Medical Officer | Mar 01, 2012 | Sale | $4.70 | 2,555 | 12,006 | 22,249 | Mar 05, 2012, 04:13 PM |
| SNTA | SVP, Chief Medical Officer | Sep 02, 2011 | Buy | $4.00 | 2,188 | 8,752 | 24,804 | Sep 06, 2011, 04:27 PM |
| SNTA | SVP, Chief Medical Officer | Sep 01, 2011 | Buy | $4.07 | 312 | 1,270 | 22,616 | Sep 06, 2011, 04:27 PM |
| SNTA | SVP, Chief Medical Officer | Mar 01, 2011 | Sale | $5.32 | 2,617 | 13,928 | 15,004 | Mar 03, 2011, 04:33 PM |
| SNTA | SVP, Chief Medical Officer | Aug 16, 2010 | Buy | $2.95 | 2,800 | 8,260 | 17,621 | Aug 20, 2010, 10:32 AM |
| SNTA | SVP, Chief Medical Officer | Aug 12, 2010 | Buy | $2.84 | 714 | 2,028 | 14,821 | Aug 20, 2010, 10:32 AM |
| Symbol | Relationship | Date | Transaction | Value($) |
| ALRN | SVP, Chief Medical Officer | Aug 16, 2019 | Buy | 44,453 |
| SNTA | SVP, Chief Medical Officer | Jun 05, 2013 | Buy | 45,800 |
| SNTA | SVP, Chief Medical Officer | Jun 29, 2012 | Buy | 16,755 |
| SNTA | SVP, Chief Medical Officer | Mar 01, 2012 | Sale | 12,006 |
| SNTA | SVP, Chief Medical Officer | Sep 02, 2011 | Buy | 8,752 |
| SNTA | SVP, Chief Medical Officer | Sep 01, 2011 | Buy | 1,270 |
| SNTA | SVP, Chief Medical Officer | Mar 01, 2011 | Sale | 13,928 |
| SNTA | SVP, Chief Medical Officer | Aug 16, 2010 | Buy | 8,260 |
| SNTA | SVP, Chief Medical Officer | Aug 12, 2010 | Buy | 2,028 |