| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| OREX | CEO & President | May 31, 2017 | Option Exercise | $1.55 | 626 | 970 | 8,356 | Jun 02, 2017, 04:55 PM |
| OREX | CEO & President | Nov 30, 2016 | Option Exercise | $1.67 | 802 | 1,339 | 6,312 | Dec 02, 2016, 05:11 PM |
| OREX | CEO & President | May 31, 2016 | Option Exercise | $0.34 | 8,777 | 2,984 | 69,285 | Jun 02, 2016, 11:23 AM |
| OREX | CEO & President | Nov 30, 2015 | Option Exercise | $2.03 | 1,761 | 3,575 | 60,508 | Feb 04, 2016, 12:04 PM |
| OREX | CEO & President | May 29, 2015 | Option Exercise | $4.17 | 721 | 3,007 | 58,747 | Feb 04, 2016, 12:04 PM |
| OREX | President and CEO | Sep 15, 2014 | Buy | $4.78 | 50,000 | 239,100 | 58,026 | Sep 15, 2014, 02:41 PM |
| OREX | President and CEO | Nov 29, 2013 | Option Exercise | $5.34 | 3,980 | 21,253 | 3,980 | Feb 11, 2014, 07:32 AM |
| CLDN | Director | Feb 04, 2014 | Buy | $8.00 | 62,500 | 500,000 | 62,500 | Feb 06, 2014, 03:50 PM |
| OREX | President and CEO | Jul 17, 2012 | Option Exercise | $1.67 | 150,000 | 250,030 | 124,238 | Jul 19, 2012, 08:07 PM |
| OREX | President and CEO | Jul 17, 2012 | Sale | $7.66 | 150,000 | 1,149,000 | 0 | Jul 19, 2012, 08:07 PM |
| OREX | President and CEO | Jul 13, 2012 | Option Exercise | $1.66 | 147,100 | 244,186 | 147,100 | Jul 13, 2012, 08:13 PM |
| OREX | President and CEO | Jul 12, 2012 | Option Exercise | $1.66 | 2,900 | 4,814 | 2,900 | Jul 13, 2012, 08:13 PM |
| OREX | President and CEO | Jul 13, 2012 | Sale | $6.70 | 147,100 | 985,570 | 0 | Jul 13, 2012, 08:13 PM |
| OREX | President and CEO | Jul 12, 2012 | Sale | $6.66 | 2,900 | 19,314 | 0 | Jul 13, 2012, 08:13 PM |
| OREX | President and CEO | Jun 28, 2012 | Option Exercise | $1.66 | 100,000 | 166,000 | 100,000 | Jun 29, 2012, 06:58 PM |
| OREX | President and CEO | Jun 29, 2012 | Option Exercise | $1.66 | 125,000 | 207,500 | 125,000 | Jun 29, 2012, 06:58 PM |
| OREX | President and CEO | Jun 28, 2012 | Sale | $5.66 | 100,000 | 566,000 | 0 | Jun 29, 2012, 06:58 PM |
| OREX | President and CEO | Jun 29, 2012 | Sale | $6.08 | 125,000 | 760,000 | 0 | Jun 29, 2012, 06:58 PM |
| AMAG | Director | May 24, 2012 | Buy | $13.55 | 2,000 | 27,102 | 2,000 | May 29, 2012, 02:17 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| OREX | CEO & President | May 31, 2017 | Option Exercise | 970 |
| OREX | CEO & President | Nov 30, 2016 | Option Exercise | 1,339 |
| OREX | CEO & President | May 31, 2016 | Option Exercise | 2,984 |
| OREX | CEO & President | Nov 30, 2015 | Option Exercise | 3,575 |
| OREX | CEO & President | May 29, 2015 | Option Exercise | 3,007 |
| OREX | President and CEO | Sep 15, 2014 | Buy | 239,100 |
| OREX | President and CEO | Nov 29, 2013 | Option Exercise | 21,253 |
| CLDN | Director | Feb 04, 2014 | Buy | 500,000 |
| OREX | President and CEO | Jul 17, 2012 | Option Exercise | 250,030 |
| OREX | President and CEO | Jul 17, 2012 | Sale | 1,149,000 |
| OREX | President and CEO | Jul 13, 2012 | Option Exercise | 244,186 |
| OREX | President and CEO | Jul 12, 2012 | Option Exercise | 4,814 |
| OREX | President and CEO | Jul 13, 2012 | Sale | 985,570 |
| OREX | President and CEO | Jul 12, 2012 | Sale | 19,314 |
| OREX | President and CEO | Jun 28, 2012 | Option Exercise | 166,000 |
| OREX | President and CEO | Jun 29, 2012 | Option Exercise | 207,500 |
| OREX | President and CEO | Jun 28, 2012 | Sale | 566,000 |
| OREX | President and CEO | Jun 29, 2012 | Sale | 760,000 |
| AMAG | Director | May 24, 2012 | Buy | 27,102 |