| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| ATRS | Director | May 24, 2022 | Option Exercise | $5.60 | 79,645 | 446,012 | 0 | May 26, 2022, 05:22 PM |
| AUPH | Chief Executive Officer | Mar 02, 2022 | Sale | $12.01 | 9,068 | 108,907 | 32,967 | Mar 04, 2022, 04:11 PM |
| ATRS | Director | Jun 10, 2021 | Option Exercise | $4.42 | 25,452 | 112,498 | 79,645 | Jun 14, 2021, 06:22 PM |
| AUPH | Chief Executive Officer | May 11, 2021 | Buy | $10.71 | 5,125 | 54,891 | 13,453 | May 12, 2021, 04:32 PM |
| ATRS | Director | Jun 11, 2020 | Option Exercise | $2.73 | 30,220 | 82,501 | 54,193 | Jun 15, 2020, 07:02 PM |
| ATRS | Director | Jun 13, 2019 | Option Exercise | $2.92 | 23,973 | 70,001 | 23,973 | Jun 14, 2019, 05:49 PM |
| CERC | Chief Executive Officer | May 18, 2018 | Buy | $3.98 | 12,500 | 49,750 | 412,500 | May 21, 2018, 07:10 PM |
| SCMP | Chief Executive Officer | Feb 13, 2018 | Option Exercise | $18.00 | 129,729 | 2,335,122 | 0 | Feb 13, 2018, 04:54 PM |
| SCMP | Chief Executive Officer | Dec 31, 2017 | Option Exercise | $9.10 | 171 | 1,556 | 4,792 | Jan 04, 2018, 05:16 PM |
| SCMP | CEO | Sep 30, 2017 | Option Exercise | $9.10 | 659 | 5,997 | 4,621 | Oct 05, 2017, 04:32 PM |
| SCMP | CEO | Jun 30, 2017 | Option Exercise | $8.93 | 673 | 6,010 | 3,962 | Jul 07, 2017, 04:45 PM |
| SCMP | CEO | Mar 31, 2017 | Option Exercise | $9.35 | 641 | 5,993 | 3,289 | May 10, 2017, 04:02 PM |
| SCMP | Chief Executive Officer | Dec 31, 2016 | Option Exercise | $10.46 | 135 | 1,412 | 2,648 | Jan 06, 2017, 04:02 PM |
| SCMP | CEO | Nov 29, 2016 | Option Exercise | $6.75 | 82,459 | 556,598 | 84,972 | Nov 30, 2016, 04:01 PM |
| SCMP | CEO | Nov 28, 2016 | Option Exercise | $6.75 | 117,541 | 793,402 | 120,054 | Nov 30, 2016, 04:01 PM |
| SCMP | CEO | Nov 28, 2016 | Sale | $16.91 | 117,541 | 1,987,618 | 2,513 | Nov 30, 2016, 04:01 PM |
| SCMP | CEO | Nov 29, 2016 | Sale | $16.75 | 82,459 | 1,381,188 | 2,513 | Nov 30, 2016, 04:01 PM |
| SCMP | Chief Executive Officer | Sep 30, 2016 | Option Exercise | $9.38 | 640 | 6,003 | 2,513 | Oct 21, 2016, 04:06 PM |
| SCMP | Chief Executive Officer | Jun 30, 2016 | Option Exercise | $9.32 | 751 | 6,999 | 1,873 | Jul 18, 2016, 05:05 PM |
| SCMP | Chief Executive Officer | Mar 31, 2016 | Option Exercise | $9.29 | 646 | 6,001 | 1,122 | Jun 16, 2016, 04:31 PM |
| SCMP | Chief Executive Officer | Dec 31, 2015 | Option Exercise | $14.70 | 476 | 6,997 | 476 | Mar 04, 2016, 05:56 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| ATRS | Director | May 24, 2022 | Option Exercise | 446,012 |
| AUPH | Chief Executive Officer | Mar 02, 2022 | Sale | 108,907 |
| ATRS | Director | Jun 10, 2021 | Option Exercise | 112,498 |
| AUPH | Chief Executive Officer | May 11, 2021 | Buy | 54,891 |
| ATRS | Director | Jun 11, 2020 | Option Exercise | 82,501 |
| ATRS | Director | Jun 13, 2019 | Option Exercise | 70,001 |
| CERC | Chief Executive Officer | May 18, 2018 | Buy | 49,750 |
| SCMP | Chief Executive Officer | Feb 13, 2018 | Option Exercise | 2,335,122 |
| SCMP | Chief Executive Officer | Dec 31, 2017 | Option Exercise | 1,556 |
| SCMP | CEO | Sep 30, 2017 | Option Exercise | 5,997 |
| SCMP | CEO | Jun 30, 2017 | Option Exercise | 6,010 |
| SCMP | CEO | Mar 31, 2017 | Option Exercise | 5,993 |
| SCMP | Chief Executive Officer | Dec 31, 2016 | Option Exercise | 1,412 |
| SCMP | CEO | Nov 29, 2016 | Option Exercise | 556,598 |
| SCMP | CEO | Nov 28, 2016 | Option Exercise | 793,402 |
| SCMP | CEO | Nov 28, 2016 | Sale | 1,987,618 |
| SCMP | CEO | Nov 29, 2016 | Sale | 1,381,188 |
| SCMP | Chief Executive Officer | Sep 30, 2016 | Option Exercise | 6,003 |
| SCMP | Chief Executive Officer | Jun 30, 2016 | Option Exercise | 6,999 |
| SCMP | Chief Executive Officer | Mar 31, 2016 | Option Exercise | 6,001 |
| SCMP | Chief Executive Officer | Dec 31, 2015 | Option Exercise | 6,997 |