| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| NTLA | Director | Jan 20, 2021 | Option Exercise | $13.78 | 20,000 | 275,600 | 30,000 | Jan 22, 2021, 04:22 PM |
| CDNA | Director | Jan 06, 2021 | Option Exercise | $14.74 | 15,000 | 221,100 | 105,893 | Jan 06, 2021, 08:37 PM |
| VCYT | Director | Oct 19, 2020 | Option Exercise | $7.60 | 10,000 | 76,000 | 10,000 | Oct 20, 2020, 05:40 PM |
| CDNA | Director | Sep 21, 2020 | Option Exercise | $5.17 | 16,424 | 84,905 | 90,893 | Sep 22, 2020, 09:14 PM |
| VCYT | Director | May 18, 2020 | Sale | $26.86 | 40,000 | 1,074,555 | 4,153 | May 19, 2020, 04:04 PM |
| GHDX | Director | Oct 01, 2019 | Option Exercise | $67.28 | 185 | 12,447 | 69,120 | Oct 03, 2019, 08:00 PM |
| VCYT | Director | Aug 02, 2019 | Option Exercise | $9.20 | 40,000 | 368,200 | 40,000 | Aug 05, 2019, 04:17 PM |
| CDNA | Director | Jul 11, 2019 | Option Exercise | $6.96 | 15,765 | 109,672 | 71,279 | Jul 15, 2019, 04:27 PM |
| GHDX | Director | Jul 01, 2019 | Option Exercise | $58.86 | 212 | 12,478 | 68,935 | Jul 03, 2019, 05:50 PM |
| GHDX | Director | Apr 01, 2019 | Option Exercise | $66.84 | 149 | 9,959 | 67,768 | Apr 03, 2019, 06:00 PM |
| URGN | Director | Feb 06, 2019 | Option Exercise | $16.99 | 15,000 | 254,850 | 15,000 | Mar 22, 2019, 07:41 PM |
| NTLA | Director | Mar 01, 2019 | Option Exercise | $16.89 | 10,000 | 168,936 | 10,000 | Mar 05, 2019, 12:00 AM |
| GHDX | Director | Feb 22, 2019 | Option Exercise | $26.01 | 10,000 | 260,100 | 77,619 | Feb 26, 2019, 04:49 PM |
| GHDX | Director | Feb 22, 2019 | Sale | $78.86 | 10,000 | 788,559 | 68,312 | Feb 26, 2019, 04:49 PM |
| GHDX | Director | Jan 01, 2019 | Option Exercise | $64.41 | 155 | 9,984 | 67,619 | Jan 03, 2019, 07:13 PM |
| GHDX | Director | Nov 08, 2018 | Option Exercise | $27.75 | 10,000 | 277,500 | 77,464 | Nov 13, 2018, 06:27 PM |
| GHDX | Director | Nov 08, 2018 | Sale | $87.93 | 10,000 | 879,262 | 76,628 | Nov 13, 2018, 06:27 PM |
| GHDX | Director | Oct 01, 2018 | Option Exercise | $70.18 | 142 | 9,966 | 67,464 | Oct 03, 2018, 08:13 PM |
| GHDX | Director | Sep 06, 2018 | Option Exercise | $34.44 | 8,250 | 284,130 | 75,572 | Sep 10, 2018, 05:02 PM |
| GHDX | Director | Sep 06, 2018 | Sale | $61.51 | 8,250 | 507,453 | 67,322 | Sep 10, 2018, 05:02 PM |
| CDNA | Director | Aug 28, 2018 | Option Exercise | $1.22 | 15,000 | 18,300 | 52,901 | Aug 29, 2018, 06:09 PM |
| GHDX | Director | Aug 07, 2018 | Option Exercise | $25.79 | 8,250 | 212,768 | 75,572 | Aug 09, 2018, 07:47 PM |
| GHDX | Director | Aug 07, 2018 | Sale | $56.22 | 8,250 | 463,800 | 68,722 | Aug 09, 2018, 07:47 PM |
| GHDX | Director | Jul 01, 2018 | Option Exercise | $50.40 | 198 | 9,979 | 67,322 | Jul 03, 2018, 04:03 PM |
| GHDX | Director | Apr 01, 2018 | Option Exercise | $31.29 | 319 | 9,982 | 67,124 | Apr 03, 2018, 08:32 PM |
| GHDX | Director | Jan 01, 2018 | Option Exercise | $34.20 | 292 | 9,986 | 66,805 | Jan 03, 2018, 06:22 PM |
| GHDX | Director | Oct 01, 2017 | Option Exercise | $32.09 | 311 | 9,980 | 66,513 | Oct 03, 2017, 06:16 PM |
| BCRX | Director | Sep 18, 2017 | Option Exercise | $4.27 | 54,250 | 231,647 | 173,660 | Sep 20, 2017, 10:07 AM |
| BCRX | Director | Sep 18, 2017 | Sale | $5.42 | 54,250 | 294,035 | 119,410 | Sep 20, 2017, 10:07 AM |
| GHDX | Director | Jul 01, 2017 | Option Exercise | $32.55 | 307 | 9,993 | 66,202 | Jul 05, 2017, 07:03 PM |
| BCRX | Director | Jun 01, 2017 | Option Exercise | $5.15 | 1,941 | 9,996 | 119,410 | Jun 02, 2017, 03:59 PM |
| GHDX | Director | May 19, 2017 | Option Exercise | $14.37 | 8,250 | 118,552 | 74,145 | May 23, 2017, 08:16 PM |
| GHDX | Director | May 19, 2017 | Sale | $29.54 | 8,250 | 243,745 | 65,895 | May 23, 2017, 08:16 PM |
| GHDX | Director | May 18, 2017 | Option Exercise | $18.05 | 16,500 | 297,743 | 82,395 | May 22, 2017, 06:59 PM |
| GHDX | Director | May 18, 2017 | Sale | $29.88 | 16,500 | 493,040 | 65,895 | May 22, 2017, 06:59 PM |
| GHDX | Director | May 16, 2017 | Option Exercise | $18.13 | 8,250 | 149,572 | 74,145 | May 18, 2017, 07:52 PM |
| GHDX | Director | May 16, 2017 | Sale | $30.68 | 8,250 | 253,102 | 65,895 | May 18, 2017, 07:52 PM |
| GHDX | Director | Apr 01, 2017 | Option Exercise | $31.49 | 317 | 9,982 | 65,895 | Apr 04, 2017, 05:27 PM |
| BCRX | Director | Mar 01, 2017 | Option Exercise | $6.24 | 1,602 | 9,996 | 117,469 | Mar 02, 2017, 03:03 PM |
| GHDX | Director | Jan 01, 2017 | Option Exercise | $29.39 | 340 | 9,993 | 65,578 | Jan 04, 2017, 07:17 PM |
| BCRX | Director | Dec 01, 2016 | Option Exercise | $5.59 | 1,788 | 9,995 | 115,867 | Dec 02, 2016, 02:03 PM |
| GHDX | Director | Oct 01, 2016 | Option Exercise | $28.92 | 345 | 9,977 | 65,238 | Oct 04, 2016, 07:43 PM |
| BCRX | Director | Sep 01, 2016 | Option Exercise | $4.11 | 2,433 | 10,000 | 114,079 | Sep 06, 2016, 03:24 PM |
| GHDX | Director | Jul 01, 2016 | Option Exercise | $26.74 | 373 | 9,974 | 64,893 | Jul 06, 2016, 06:42 PM |
| BCRX | Director | May 31, 2016 | Option Exercise | $3.39 | 2,581 | 8,750 | 111,646 | Jun 02, 2016, 09:42 AM |
| GHDX | Director | Apr 01, 2016 | Option Exercise | $25.48 | 392 | 9,988 | 64,520 | Apr 04, 2016, 08:58 PM |
| BCRX | Director | Feb 29, 2016 | Option Exercise | $1.99 | 4,396 | 8,748 | 109,065 | Mar 01, 2016, 04:03 PM |
| FPRX | Director | Jan 11, 2016 | Option Exercise | $9.93 | 24,695 | 245,294 | 24,807 | Jan 13, 2016, 05:05 PM |
| GHDX | Director | Jan 01, 2016 | Option Exercise | $35.20 | 284 | 9,997 | 64,128 | Jan 05, 2016, 04:17 PM |
| BCRX | Director | Nov 30, 2015 | Option Exercise | $10.61 | 824 | 8,743 | 104,669 | Dec 03, 2015, 04:19 PM |
| GHDX | Director | Oct 01, 2015 | Option Exercise | $21.34 | 468 | 9,987 | 63,844 | Oct 05, 2015, 05:01 PM |
| BCRX | Director | Aug 31, 2015 | Option Exercise | $11.64 | 751 | 8,742 | 103,845 | Sep 02, 2015, 02:22 PM |
| GHDX | Director | Jul 01, 2015 | Option Exercise | $27.34 | 365 | 9,979 | 63,376 | Jul 06, 2015, 05:03 PM |
| BCRX | Director | May 29, 2015 | Option Exercise | $11.21 | 780 | 8,744 | 103,094 | Jun 01, 2015, 03:53 PM |
| GHDX | Director | Apr 01, 2015 | Option Exercise | $30.43 | 328 | 9,981 | 63,011 | Apr 03, 2015, 04:21 PM |
| BCRX | Director | Feb 27, 2015 | Option Exercise | $10.20 | 857 | 8,741 | 102,314 | Mar 03, 2015, 03:45 PM |
| BCRX | Director | Jan 08, 2015 | Option Exercise | $1.29 | 100,000 | 129,000 | 101,457 | Jan 09, 2015, 01:19 PM |
| GHDX | Director | Jan 01, 2015 | Option Exercise | $31.97 | 312 | 9,975 | 62,683 | Jan 05, 2015, 04:27 PM |
| BCRX | Director | Nov 28, 2014 | Option Exercise | $10.81 | 809 | 8,745 | 1,457 | Dec 03, 2014, 03:41 PM |
| GHDX | Director | Oct 01, 2014 | Option Exercise | $28.54 | 350 | 9,989 | 62,371 | Oct 03, 2014, 04:26 PM |
| BCRX | Director | Aug 29, 2014 | Option Exercise | $13.50 | 648 | 8,748 | 648 | Sep 02, 2014, 04:08 PM |
| GHDX | Director | Jul 01, 2014 | Option Exercise | $27.86 | 358 | 9,974 | 62,021 | Jul 03, 2014, 04:31 PM |
| GHDX | Director | Apr 01, 2014 | Option Exercise | $26.57 | 376 | 9,990 | 61,663 | Apr 03, 2014, 03:57 PM |
| GHDX | Director | Jan 01, 2014 | Option Exercise | $29.27 | 341 | 9,981 | 61,287 | Jan 03, 2014, 07:03 PM |
| GHDX | Director | Oct 01, 2013 | Option Exercise | $30.33 | 329 | 9,979 | 60,946 | Oct 03, 2013, 08:07 PM |
| GHDX | Director | Jul 01, 2013 | Option Exercise | $32.85 | 303 | 9,954 | 60,617 | Jul 03, 2013, 05:14 PM |
| GHDX | Director | Apr 01, 2013 | Option Exercise | $27.99 | 357 | 9,992 | 60,314 | Apr 03, 2013, 04:55 PM |
| GHDX | Director | Jan 01, 2013 | Option Exercise | $27.24 | 367 | 9,997 | 59,957 | Jan 03, 2013, 05:06 PM |
| GHDX | Director | Oct 01, 2012 | Option Exercise | $35.89 | 288 | 10,336 | 59,590 | Oct 03, 2012, 06:44 PM |
| GHDX | Director | Aug 01, 2012 | Option Exercise | $10.73 | 8,250 | 88,522 | 59,302 | Aug 31, 2012, 05:38 PM |
| GHDX | Director | Jul 01, 2012 | Option Exercise | $33.40 | 299 | 9,987 | 51,052 | Jul 03, 2012, 07:23 PM |
| GHDX | Director | Apr 01, 2012 | Option Exercise | $30.61 | 326 | 9,979 | 50,753 | Apr 03, 2012, 02:13 PM |
| GHDX | Director | Jan 01, 2012 | Option Exercise | $25.39 | 393 | 9,978 | 50,427 | Jan 06, 2012, 06:33 PM |
| GHDX | Director | Oct 01, 2011 | Option Exercise | $21.98 | 454 | 9,979 | 49,903 | Oct 04, 2011, 06:41 PM |
| GHDX | Director | Jul 01, 2011 | Option Exercise | $27.91 | 358 | 9,992 | 49,449 | Jul 06, 2011, 10:10 AM |
| GHDX | Director | Apr 01, 2011 | Option Exercise | $24.60 | 406 | 9,988 | 49,091 | Apr 05, 2011, 06:07 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| NTLA | Director | Jan 20, 2021 | Option Exercise | 275,600 |
| CDNA | Director | Jan 06, 2021 | Option Exercise | 221,100 |
| VCYT | Director | Oct 19, 2020 | Option Exercise | 76,000 |
| CDNA | Director | Sep 21, 2020 | Option Exercise | 84,905 |
| VCYT | Director | May 18, 2020 | Sale | 1,074,555 |
| GHDX | Director | Oct 01, 2019 | Option Exercise | 12,447 |
| VCYT | Director | Aug 02, 2019 | Option Exercise | 368,200 |
| CDNA | Director | Jul 11, 2019 | Option Exercise | 109,672 |
| GHDX | Director | Jul 01, 2019 | Option Exercise | 12,478 |
| GHDX | Director | Apr 01, 2019 | Option Exercise | 9,959 |
| URGN | Director | Feb 06, 2019 | Option Exercise | 254,850 |
| NTLA | Director | Mar 01, 2019 | Option Exercise | 168,936 |
| GHDX | Director | Feb 22, 2019 | Option Exercise | 260,100 |
| GHDX | Director | Feb 22, 2019 | Sale | 788,559 |
| GHDX | Director | Jan 01, 2019 | Option Exercise | 9,984 |
| GHDX | Director | Nov 08, 2018 | Option Exercise | 277,500 |
| GHDX | Director | Nov 08, 2018 | Sale | 879,262 |
| GHDX | Director | Oct 01, 2018 | Option Exercise | 9,966 |
| GHDX | Director | Sep 06, 2018 | Option Exercise | 284,130 |
| GHDX | Director | Sep 06, 2018 | Sale | 507,453 |
| CDNA | Director | Aug 28, 2018 | Option Exercise | 18,300 |
| GHDX | Director | Aug 07, 2018 | Option Exercise | 212,768 |
| GHDX | Director | Aug 07, 2018 | Sale | 463,800 |
| GHDX | Director | Jul 01, 2018 | Option Exercise | 9,979 |
| GHDX | Director | Apr 01, 2018 | Option Exercise | 9,982 |
| GHDX | Director | Jan 01, 2018 | Option Exercise | 9,986 |
| GHDX | Director | Oct 01, 2017 | Option Exercise | 9,980 |
| BCRX | Director | Sep 18, 2017 | Option Exercise | 231,647 |
| BCRX | Director | Sep 18, 2017 | Sale | 294,035 |
| GHDX | Director | Jul 01, 2017 | Option Exercise | 9,993 |
| BCRX | Director | Jun 01, 2017 | Option Exercise | 9,996 |
| GHDX | Director | May 19, 2017 | Option Exercise | 118,552 |
| GHDX | Director | May 19, 2017 | Sale | 243,745 |
| GHDX | Director | May 18, 2017 | Option Exercise | 297,743 |
| GHDX | Director | May 18, 2017 | Sale | 493,040 |
| GHDX | Director | May 16, 2017 | Option Exercise | 149,572 |
| GHDX | Director | May 16, 2017 | Sale | 253,102 |
| GHDX | Director | Apr 01, 2017 | Option Exercise | 9,982 |
| BCRX | Director | Mar 01, 2017 | Option Exercise | 9,996 |
| GHDX | Director | Jan 01, 2017 | Option Exercise | 9,993 |
| BCRX | Director | Dec 01, 2016 | Option Exercise | 9,995 |
| GHDX | Director | Oct 01, 2016 | Option Exercise | 9,977 |
| BCRX | Director | Sep 01, 2016 | Option Exercise | 10,000 |
| GHDX | Director | Jul 01, 2016 | Option Exercise | 9,974 |
| BCRX | Director | May 31, 2016 | Option Exercise | 8,750 |
| GHDX | Director | Apr 01, 2016 | Option Exercise | 9,988 |
| BCRX | Director | Feb 29, 2016 | Option Exercise | 8,748 |
| FPRX | Director | Jan 11, 2016 | Option Exercise | 245,294 |
| GHDX | Director | Jan 01, 2016 | Option Exercise | 9,997 |
| BCRX | Director | Nov 30, 2015 | Option Exercise | 8,743 |
| GHDX | Director | Oct 01, 2015 | Option Exercise | 9,987 |
| BCRX | Director | Aug 31, 2015 | Option Exercise | 8,742 |
| GHDX | Director | Jul 01, 2015 | Option Exercise | 9,979 |
| BCRX | Director | May 29, 2015 | Option Exercise | 8,744 |
| GHDX | Director | Apr 01, 2015 | Option Exercise | 9,981 |
| BCRX | Director | Feb 27, 2015 | Option Exercise | 8,741 |
| BCRX | Director | Jan 08, 2015 | Option Exercise | 129,000 |
| GHDX | Director | Jan 01, 2015 | Option Exercise | 9,975 |
| BCRX | Director | Nov 28, 2014 | Option Exercise | 8,745 |
| GHDX | Director | Oct 01, 2014 | Option Exercise | 9,989 |
| BCRX | Director | Aug 29, 2014 | Option Exercise | 8,748 |
| GHDX | Director | Jul 01, 2014 | Option Exercise | 9,974 |
| GHDX | Director | Apr 01, 2014 | Option Exercise | 9,990 |
| GHDX | Director | Jan 01, 2014 | Option Exercise | 9,981 |
| GHDX | Director | Oct 01, 2013 | Option Exercise | 9,979 |
| GHDX | Director | Jul 01, 2013 | Option Exercise | 9,954 |
| GHDX | Director | Apr 01, 2013 | Option Exercise | 9,992 |
| GHDX | Director | Jan 01, 2013 | Option Exercise | 9,997 |
| GHDX | Director | Oct 01, 2012 | Option Exercise | 10,336 |
| GHDX | Director | Aug 01, 2012 | Option Exercise | 88,522 |
| GHDX | Director | Jul 01, 2012 | Option Exercise | 9,987 |
| GHDX | Director | Apr 01, 2012 | Option Exercise | 9,979 |
| GHDX | Director | Jan 01, 2012 | Option Exercise | 9,978 |
| GHDX | Director | Oct 01, 2011 | Option Exercise | 9,979 |
| GHDX | Director | Jul 01, 2011 | Option Exercise | 9,992 |
| GHDX | Director | Apr 01, 2011 | Option Exercise | 9,988 |