| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| TCRX | Chief Executive Officer | May 18, 2022 | Buy | $3.59 | 25,000 | 89,821 | 171,569 | May 20, 2022, 04:15 PM |
| TCRX | Chief Executive Officer | Dec 23, 2021 | Option Exercise | $1.97 | 48,670 | 95,880 | 146,569 | Dec 27, 2021, 04:30 PM |
| TCRX | Chief Executive Officer | Sep 08, 2021 | Buy | $8.73 | 11,000 | 96,066 | 97,899 | Sep 09, 2021, 04:43 PM |
| PTCT | Director | Oct 16, 2020 | Option Exercise | $11.02 | 27,000 | 297,510 | 16,650 | Oct 20, 2020, 04:34 PM |
| PTCT | Director | Oct 16, 2020 | Sale | $51.54 | 27,000 | 1,391,544 | 2,350 | Oct 20, 2020, 04:34 PM |
| RCKT | Director | Dec 13, 2018 | Sale | $15.19 | 38,768 | 588,886 | 95,160 | Dec 14, 2018, 09:06 PM |
| RCKT | Director | Dec 07, 2018 | Sale | $14.91 | 4,923 | 73,402 | 133,928 | Dec 10, 2018, 05:03 PM |
| RCKT | Director | Dec 06, 2018 | Sale | $15.15 | 52,809 | 800,056 | 138,851 | Dec 10, 2018, 05:03 PM |
| ITEK | President and CEO | Jan 06, 2017 | Buy | $1.75 | 60,000 | 105,000 | 62,765 | Jan 09, 2017, 05:54 PM |
| PTCT | Director | Jul 06, 2015 | Option Exercise | $10.85 | 15,000 | 162,750 | 23,604 | Jul 06, 2015, 09:21 PM |
| PTCT | Director | Jul 06, 2015 | Sale | $47.52 | 23,604 | 1,121,694 | 700 | Jul 06, 2015, 09:21 PM |
| PTCT | Director | Mar 23, 2015 | Sale | $69.04 | 2,317 | 159,957 | 8,721 | Mar 23, 2015, 05:58 PM |
| PTCT | Director | Mar 21, 2014 | Sale | $30.93 | 2,317 | 71,666 | 12,038 | Mar 24, 2014, 06:18 PM |
| HGSI | Chief Financial Officer | Jul 30, 2012 | Option Exercise | $14.25 | 90,835 | 1,294,399 | 0 | Aug 01, 2012, 11:53 AM |
| TCRD | Director | Dec 06, 2010 | Buy | $13.00 | 12,100 | 157,277 | 38,500 | Dec 07, 2010, 01:42 PM |
| TCRD | Director | Nov 24, 2010 | Buy | $12.84 | 200 | 2,568 | 26,400 | Nov 29, 2010, 04:12 PM |
| TCRD | Director | Nov 22, 2010 | Buy | $12.84 | 101 | 1,296 | 26,100 | Nov 29, 2010, 04:11 PM |
| TCRD | Director | Nov 23, 2010 | Buy | $12.83 | 100 | 1,283 | 26,200 | Nov 29, 2010, 04:11 PM |
| TCRD | Director | Nov 23, 2010 | Buy | $12.83 | 100 | 1,283 | 26,200 | Nov 24, 2010, 10:11 AM |
| TCRD | Director | Nov 22, 2010 | Buy | $12.84 | 101 | 1,296 | 26,100 | Nov 24, 2010, 10:11 AM |
| TCRD | Director | Nov 19, 2010 | Buy | $12.84 | 499 | 6,406 | 25,999 | Nov 22, 2010, 04:37 PM |
| TCRD | Director | Nov 18, 2010 | Buy | $12.84 | 11,400 | 146,365 | 25,500 | Nov 22, 2010, 04:37 PM |
| TCRD | Director | Nov 17, 2010 | Buy | $12.84 | 5,478 | 70,324 | 14,100 | Nov 18, 2010, 05:05 PM |
| TCRD | Director | Nov 16, 2010 | Buy | $12.84 | 8,622 | 110,706 | 8,622 | Nov 18, 2010, 05:05 PM |
| BSMD | Director | Sep 10, 2010 | Option Exercise | $4.38 | 20,055 | 87,841 | 0 | Sep 10, 2010, 02:01 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| TCRX | Chief Executive Officer | May 18, 2022 | Buy | 89,821 |
| TCRX | Chief Executive Officer | Dec 23, 2021 | Option Exercise | 95,880 |
| TCRX | Chief Executive Officer | Sep 08, 2021 | Buy | 96,066 |
| PTCT | Director | Oct 16, 2020 | Option Exercise | 297,510 |
| PTCT | Director | Oct 16, 2020 | Sale | 1,391,544 |
| RCKT | Director | Dec 13, 2018 | Sale | 588,886 |
| RCKT | Director | Dec 07, 2018 | Sale | 73,402 |
| RCKT | Director | Dec 06, 2018 | Sale | 800,056 |
| ITEK | President and CEO | Jan 06, 2017 | Buy | 105,000 |
| PTCT | Director | Jul 06, 2015 | Option Exercise | 162,750 |
| PTCT | Director | Jul 06, 2015 | Sale | 1,121,694 |
| PTCT | Director | Mar 23, 2015 | Sale | 159,957 |
| PTCT | Director | Mar 21, 2014 | Sale | 71,666 |
| HGSI | Chief Financial Officer | Jul 30, 2012 | Option Exercise | 1,294,399 |
| TCRD | Director | Dec 06, 2010 | Buy | 157,277 |
| TCRD | Director | Nov 24, 2010 | Buy | 2,568 |
| TCRD | Director | Nov 22, 2010 | Buy | 1,296 |
| TCRD | Director | Nov 23, 2010 | Buy | 1,283 |
| TCRD | Director | Nov 23, 2010 | Buy | 1,283 |
| TCRD | Director | Nov 22, 2010 | Buy | 1,296 |
| TCRD | Director | Nov 19, 2010 | Buy | 6,406 |
| TCRD | Director | Nov 18, 2010 | Buy | 146,365 |
| TCRD | Director | Nov 17, 2010 | Buy | 70,324 |
| TCRD | Director | Nov 16, 2010 | Buy | 110,706 |
| BSMD | Director | Sep 10, 2010 | Option Exercise | 87,841 |