| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| THRX | President and CEO | Dec 21, 2021 | Buy | $9.76 | 2,600 | 25,381 | 348,530 | Dec 22, 2021, 06:26 PM |
| ARIA | President, R&D, CSO | Jan 31, 2017 | Option Exercise | $23.82 | 9,610 | 228,886 | 219,867 | Feb 02, 2017, 04:41 PM |
| ARIA | President, R&D, CSO | Oct 24, 2016 | Sale | $9.56 | 19,638 | 187,739 | 197,884 | Oct 25, 2016, 04:07 PM |
| ARIA | President, R&D, CSO | Sep 28, 2016 | Sale | $13.98 | 8,750 | 122,311 | 217,522 | Sep 28, 2016, 04:19 PM |
| ARIA | President, R&D, CSO | Sep 22, 2016 | Sale | $13.43 | 20,000 | 268,536 | 208,772 | Sep 23, 2016, 05:46 PM |
| ARIA | President, R&D, CSO | Sep 15, 2016 | Option Exercise | $7.82 | 59,369 | 464,266 | 288,141 | Sep 16, 2016, 05:08 PM |
| ARIA | President, R&D, CSO | Sep 15, 2016 | Sale | $11.73 | 59,369 | 696,398 | 228,772 | Sep 16, 2016, 05:08 PM |
| ARIA | President, R&D, CSO | Aug 22, 2016 | Sale | $10.47 | 19,436 | 203,538 | 228,772 | Aug 23, 2016, 04:12 PM |
| ARIA | President, R&D, CSO | Aug 12, 2016 | Option Exercise | $7.69 | 25,000 | 192,250 | 273,208 | Aug 15, 2016, 04:16 PM |
| ARIA | President, R&D, CSO | Aug 12, 2016 | Sale | $10.50 | 25,000 | 262,500 | 248,208 | Aug 15, 2016, 04:16 PM |
| ARIA | President, R&D, CSO | Jul 22, 2016 | Sale | $8.11 | 18,286 | 148,230 | 248,208 | Jul 25, 2016, 04:39 PM |
| ARIA | President, R&D, CSO | Jul 01, 2016 | Option Exercise | $3.88 | 61,422 | 238,585 | 297,916 | Jul 05, 2016, 04:07 PM |
| ARIA | President, R&D, CSO | Jul 01, 2016 | Sale | $7.48 | 61,422 | 459,634 | 266,494 | Jul 05, 2016, 04:07 PM |
| ARIA | President, R&D, CSO | Jun 22, 2016 | Sale | $7.28 | 23,999 | 174,638 | 264,742 | Jun 23, 2016, 04:11 PM |
| ARIA | President, R&D, CSO | May 23, 2016 | Sale | $8.08 | 17,762 | 143,430 | 288,741 | May 25, 2016, 04:04 PM |
| ARIA | President, R&D, CSO | May 02, 2016 | Sale | $7.13 | 11,700 | 83,478 | 306,503 | May 02, 2016, 05:28 PM |
| ARIA | President, R&D, CSO | Apr 22, 2016 | Sale | $7.37 | 21,409 | 157,864 | 294,803 | Apr 25, 2016, 04:04 PM |
| ARIA | President, R&D, CSO | Mar 22, 2016 | Sale | $6.58 | 23,834 | 156,871 | 316,212 | Mar 23, 2016, 04:41 PM |
| ARIA | President, R&D, CSO | Mar 19, 2016 | Sale | $6.47 | 5,417 | 35,039 | 340,046 | Mar 22, 2016, 04:01 PM |
| ARIA | President, R&D, CSO | Mar 03, 2016 | Sale | $6.12 | 9,625 | 58,867 | 334,630 | Mar 03, 2016, 08:00 PM |
| ARIA | President, R&D, CSO | Mar 02, 2016 | Sale | $6.00 | 25,047 | 150,282 | 344,255 | Mar 03, 2016, 08:00 PM |
| ARIA | President, R&D, CSO | Feb 01, 2016 | Sale | $4.81 | 14,667 | 70,517 | 350,052 | Feb 03, 2016, 04:43 PM |
| ARIA | President, R&D, CSO | Sep 28, 2015 | Sale | $6.46 | 8,750 | 56,560 | 334,086 | Sep 28, 2015, 05:36 PM |
| ARIA | President, R&D, CSO | Jul 16, 2015 | Sale | $8.54 | 7,000 | 59,797 | 325,336 | Jul 16, 2015, 05:40 PM |
| ARIA | President, R&D, CSO | Apr 23, 2015 | Sale | $9.50 | 123,766 | 1,175,777 | 316,548 | Apr 27, 2015, 04:14 PM |
| ARIA | President, R&D, CSO | Mar 19, 2015 | Option Exercise | $7.56 | 20,657 | 156,167 | 460,971 | Mar 23, 2015, 05:45 PM |
| ARIA | President, R&D, CSO | Mar 19, 2015 | Sale | $9.00 | 20,657 | 185,913 | 440,314 | Mar 23, 2015, 05:45 PM |
| ARIA | President, R&D, CSO | Mar 23, 2015 | Sale | $8.55 | 6,667 | 57,016 | 440,314 | Mar 23, 2015, 05:45 PM |
| ARIA | President, R&D, CSO | Mar 20, 2015 | Sale | $8.84 | 5,417 | 47,910 | 433,648 | Mar 23, 2015, 05:45 PM |
| ARIA | President, R&D, CSO | Feb 20, 2015 | Option Exercise | $3.54 | 49,035 | 173,419 | 453,231 | Feb 24, 2015, 04:23 PM |
| ARIA | President, R&D, CSO | Feb 20, 2015 | Sale | $8.00 | 49,035 | 392,280 | 428,232 | Feb 24, 2015, 04:23 PM |
| ARIA | President, R&D, CSO | Feb 02, 2015 | Sale | $6.33 | 14,667 | 92,820 | 428,232 | Feb 04, 2015, 04:17 PM |
| ARIA | President, R&D, CSO | Jul 15, 2014 | Option Exercise | $5.57 | 4,564 | 25,421 | 413,565 | Jul 17, 2014, 05:02 PM |
| ARIA | President, R&D, CSO | Apr 02, 2014 | Sale | $8.21 | 6,500 | 53,337 | 403,028 | Apr 03, 2014, 04:27 PM |
| ARIA | President, R&D, CSO | Mar 19, 2014 | Option Exercise | $8.19 | 3,442 | 28,190 | 387,711 | Mar 21, 2014, 05:20 PM |
| ARIA | President, R&D, CSO | Mar 21, 2014 | Sale | $7.89 | 6,667 | 52,583 | 394,377 | Mar 21, 2014, 05:20 PM |
| ARIA | President, R&D, CSO | Dec 19, 2013 | Sale | $5.14 | 9,750 | 50,115 | 380,319 | Dec 20, 2013, 04:39 PM |
| ARIA | President, R&D, CSO | Sep 06, 2013 | Sale | $22.00 | 8,449 | 185,878 | 370,451 | Sep 10, 2013, 04:32 PM |
| ARIA | President, R&D, CSO | Jul 18, 2013 | Sale | $19.79 | 14,000 | 277,045 | 378,900 | Jul 18, 2013, 05:47 PM |
| ARIA | President, R&D, CSO | Apr 02, 2013 | Sale | $18.04 | 6,500 | 117,245 | 363,705 | Apr 03, 2013, 04:53 PM |
| ARIA | President, R&D, CSO | Mar 25, 2013 | Sale | $18.87 | 19,167 | 361,766 | 357,205 | Mar 26, 2013, 04:34 PM |
| ARIA | President, R&D, CSO | Mar 22, 2013 | Sale | $19.46 | 6,667 | 129,718 | 338,039 | Mar 22, 2013, 06:03 PM |
| ARIA | President, R&D, CSO | Mar 04, 2013 | Sale | $21.00 | 9,838 | 206,598 | 331,372 | Mar 05, 2013, 04:44 PM |
| ARIA | President, R&D, CSO | Jan 15, 2013 | Option Exercise | $5.05 | 57,939 | 292,414 | 341,210 | Jan 17, 2013, 04:44 PM |
| ARIA | President, R&D, CSO | Dec 20, 2012 | Option Exercise | $5.23 | 27,000 | 141,210 | 282,940 | Dec 21, 2012, 04:28 PM |
| ARIA | President, R&D, CSO | Dec 18, 2012 | Option Exercise | $20.18 | 8,142 | 164,306 | 255,940 | Dec 20, 2012, 04:41 PM |
| ARIA | President, R&D, CSO | Aug 30, 2012 | Option Exercise | $3.25 | 10,001 | 32,503 | 244,170 | Sep 04, 2012, 04:08 PM |
| ARIA | President, R&D, CSO | Aug 15, 2012 | Option Exercise | $7.56 | 36,843 | 278,533 | 271,012 | Aug 16, 2012, 04:07 PM |
| ARIA | President, R&D, CSO | Aug 15, 2012 | Sale | $20.00 | 36,843 | 736,860 | 234,169 | Aug 16, 2012, 04:07 PM |
| ARIA | President, R&D, CSO | Jul 30, 2012 | Option Exercise | $5.23 | 23,234 | 121,514 | 257,403 | Aug 01, 2012, 04:07 PM |
| ARIA | President, R&D, CSO | Jul 30, 2012 | Sale | $19.00 | 23,234 | 441,446 | 234,169 | Aug 01, 2012, 04:07 PM |
| ARIA | President, R&D, CSO | May 02, 2012 | Option Exercise | $7.44 | 20,000 | 148,800 | 253,778 | May 04, 2012, 04:31 PM |
| ARIA | President, R&D, CSO | May 02, 2012 | Sale | $17.00 | 20,000 | 340,000 | 233,778 | May 04, 2012, 04:31 PM |
| ARIA | President, R&D, CSO | Apr 17, 2012 | Sale | $15.00 | 7,111 | 106,665 | 233,778 | Apr 17, 2012, 04:28 PM |
| ARIA | President, R&D, CSO | Apr 13, 2012 | Sale | $14.83 | 31,600 | 468,628 | 240,889 | Apr 17, 2012, 04:28 PM |
| ARIA | President, R&D, CSO | Mar 26, 2012 | Sale | $16.34 | 26,061 | 425,876 | 264,689 | Apr 03, 2012, 05:58 PM |
| ARIA | President, R&D, CSO | Apr 03, 2012 | Sale | $16.18 | 5,200 | 84,134 | 272,489 | Apr 03, 2012, 05:58 PM |
| ARIA | President, R&D, CSO | Mar 26, 2012 | Option Exercise | $6.39 | 7,500 | 47,925 | 298,250 | Mar 28, 2012, 04:18 PM |
| ARIA | President, R&D, CSO | Mar 26, 2012 | Sale | $16.00 | 7,500 | 120,000 | 290,750 | Mar 28, 2012, 04:18 PM |
| ARIA | President, R&D, CSO | Mar 23, 2012 | Sale | $15.41 | 15,333 | 236,211 | 290,750 | Mar 26, 2012, 04:37 PM |
| ARIA | President, R&D, CSO | Mar 20, 2012 | Sale | $15.02 | 36,400 | 546,622 | 267,750 | Mar 21, 2012, 06:02 PM |
| ARIA | President, R&D, CSO | Mar 16, 2012 | Option Exercise | $4.13 | 15,064 | 62,192 | 213,150 | Mar 19, 2012, 04:30 PM |
| ARIA | President, R&D, CSO | Feb 14, 2012 | Option Exercise | $3.90 | 16,500 | 64,350 | 138,150 | Feb 17, 2012, 04:29 PM |
| ARIA | President, R&D, CSO | Feb 14, 2012 | Sale | $15.50 | 16,500 | 255,750 | 121,650 | Feb 17, 2012, 04:29 PM |
| ARIA | President, R&D, CSO | Feb 14, 2012 | Option Exercise | $4.09 | 76,436 | 312,908 | 196,318 | Feb 16, 2012, 04:29 PM |
| ARIA | President, R&D, CSO | Feb 14, 2012 | Sale | $15.12 | 76,436 | 1,155,781 | 119,882 | Feb 16, 2012, 04:29 PM |
| ARIA | President, R&D, CSO | Jun 07, 2011 | Option Exercise | $8.65 | 43,766 | 378,576 | 196,318 | Jun 09, 2011, 04:22 PM |
| ARIA | President, R&D, CSO | Jun 07, 2011 | Option Exercise | $5.65 | 60,000 | 339,000 | 240,084 | Jun 09, 2011, 04:22 PM |
| ARIA | President, R&D, CSO | Apr 11, 2011 | Option Exercise | $7.76 | 13,289 | 103,123 | 180,084 | Apr 13, 2011, 06:30 PM |
| ARIA | President, R&D, CSO | Mar 22, 2011 | Option Exercise | $6.39 | 12,273 | 78,424 | 141,373 | Mar 24, 2011, 05:31 PM |
| ARIA | Pres., R & D., Chief Sci. Off. | Oct 26, 2010 | Buy | $3.70 | 10,000 | 37,000 | 117,437 | Oct 27, 2010, 04:30 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| THRX | President and CEO | Dec 21, 2021 | Buy | 25,381 |
| ARIA | President, R&D, CSO | Jan 31, 2017 | Option Exercise | 228,886 |
| ARIA | President, R&D, CSO | Oct 24, 2016 | Sale | 187,739 |
| ARIA | President, R&D, CSO | Sep 28, 2016 | Sale | 122,311 |
| ARIA | President, R&D, CSO | Sep 22, 2016 | Sale | 268,536 |
| ARIA | President, R&D, CSO | Sep 15, 2016 | Option Exercise | 464,266 |
| ARIA | President, R&D, CSO | Sep 15, 2016 | Sale | 696,398 |
| ARIA | President, R&D, CSO | Aug 22, 2016 | Sale | 203,538 |
| ARIA | President, R&D, CSO | Aug 12, 2016 | Option Exercise | 192,250 |
| ARIA | President, R&D, CSO | Aug 12, 2016 | Sale | 262,500 |
| ARIA | President, R&D, CSO | Jul 22, 2016 | Sale | 148,230 |
| ARIA | President, R&D, CSO | Jul 01, 2016 | Option Exercise | 238,585 |
| ARIA | President, R&D, CSO | Jul 01, 2016 | Sale | 459,634 |
| ARIA | President, R&D, CSO | Jun 22, 2016 | Sale | 174,638 |
| ARIA | President, R&D, CSO | May 23, 2016 | Sale | 143,430 |
| ARIA | President, R&D, CSO | May 02, 2016 | Sale | 83,478 |
| ARIA | President, R&D, CSO | Apr 22, 2016 | Sale | 157,864 |
| ARIA | President, R&D, CSO | Mar 22, 2016 | Sale | 156,871 |
| ARIA | President, R&D, CSO | Mar 19, 2016 | Sale | 35,039 |
| ARIA | President, R&D, CSO | Mar 03, 2016 | Sale | 58,867 |
| ARIA | President, R&D, CSO | Mar 02, 2016 | Sale | 150,282 |
| ARIA | President, R&D, CSO | Feb 01, 2016 | Sale | 70,517 |
| ARIA | President, R&D, CSO | Sep 28, 2015 | Sale | 56,560 |
| ARIA | President, R&D, CSO | Jul 16, 2015 | Sale | 59,797 |
| ARIA | President, R&D, CSO | Apr 23, 2015 | Sale | 1,175,777 |
| ARIA | President, R&D, CSO | Mar 19, 2015 | Option Exercise | 156,167 |
| ARIA | President, R&D, CSO | Mar 19, 2015 | Sale | 185,913 |
| ARIA | President, R&D, CSO | Mar 23, 2015 | Sale | 57,016 |
| ARIA | President, R&D, CSO | Mar 20, 2015 | Sale | 47,910 |
| ARIA | President, R&D, CSO | Feb 20, 2015 | Option Exercise | 173,419 |
| ARIA | President, R&D, CSO | Feb 20, 2015 | Sale | 392,280 |
| ARIA | President, R&D, CSO | Feb 02, 2015 | Sale | 92,820 |
| ARIA | President, R&D, CSO | Jul 15, 2014 | Option Exercise | 25,421 |
| ARIA | President, R&D, CSO | Apr 02, 2014 | Sale | 53,337 |
| ARIA | President, R&D, CSO | Mar 19, 2014 | Option Exercise | 28,190 |
| ARIA | President, R&D, CSO | Mar 21, 2014 | Sale | 52,583 |
| ARIA | President, R&D, CSO | Dec 19, 2013 | Sale | 50,115 |
| ARIA | President, R&D, CSO | Sep 06, 2013 | Sale | 185,878 |
| ARIA | President, R&D, CSO | Jul 18, 2013 | Sale | 277,045 |
| ARIA | President, R&D, CSO | Apr 02, 2013 | Sale | 117,245 |
| ARIA | President, R&D, CSO | Mar 25, 2013 | Sale | 361,766 |
| ARIA | President, R&D, CSO | Mar 22, 2013 | Sale | 129,718 |
| ARIA | President, R&D, CSO | Mar 04, 2013 | Sale | 206,598 |
| ARIA | President, R&D, CSO | Jan 15, 2013 | Option Exercise | 292,414 |
| ARIA | President, R&D, CSO | Dec 20, 2012 | Option Exercise | 141,210 |
| ARIA | President, R&D, CSO | Dec 18, 2012 | Option Exercise | 164,306 |
| ARIA | President, R&D, CSO | Aug 30, 2012 | Option Exercise | 32,503 |
| ARIA | President, R&D, CSO | Aug 15, 2012 | Option Exercise | 278,533 |
| ARIA | President, R&D, CSO | Aug 15, 2012 | Sale | 736,860 |
| ARIA | President, R&D, CSO | Jul 30, 2012 | Option Exercise | 121,514 |
| ARIA | President, R&D, CSO | Jul 30, 2012 | Sale | 441,446 |
| ARIA | President, R&D, CSO | May 02, 2012 | Option Exercise | 148,800 |
| ARIA | President, R&D, CSO | May 02, 2012 | Sale | 340,000 |
| ARIA | President, R&D, CSO | Apr 17, 2012 | Sale | 106,665 |
| ARIA | President, R&D, CSO | Apr 13, 2012 | Sale | 468,628 |
| ARIA | President, R&D, CSO | Mar 26, 2012 | Sale | 425,876 |
| ARIA | President, R&D, CSO | Apr 03, 2012 | Sale | 84,134 |
| ARIA | President, R&D, CSO | Mar 26, 2012 | Option Exercise | 47,925 |
| ARIA | President, R&D, CSO | Mar 26, 2012 | Sale | 120,000 |
| ARIA | President, R&D, CSO | Mar 23, 2012 | Sale | 236,211 |
| ARIA | President, R&D, CSO | Mar 20, 2012 | Sale | 546,622 |
| ARIA | President, R&D, CSO | Mar 16, 2012 | Option Exercise | 62,192 |
| ARIA | President, R&D, CSO | Feb 14, 2012 | Option Exercise | 64,350 |
| ARIA | President, R&D, CSO | Feb 14, 2012 | Sale | 255,750 |
| ARIA | President, R&D, CSO | Feb 14, 2012 | Option Exercise | 312,908 |
| ARIA | President, R&D, CSO | Feb 14, 2012 | Sale | 1,155,781 |
| ARIA | President, R&D, CSO | Jun 07, 2011 | Option Exercise | 378,576 |
| ARIA | President, R&D, CSO | Jun 07, 2011 | Option Exercise | 339,000 |
| ARIA | President, R&D, CSO | Apr 11, 2011 | Option Exercise | 103,123 |
| ARIA | President, R&D, CSO | Mar 22, 2011 | Option Exercise | 78,424 |
| ARIA | Pres., R & D., Chief Sci. Off. | Oct 26, 2010 | Buy | 37,000 |