Insider Transactions by HBM BIOVENTURES CAYMAN LTD

Symbol Relationship Date Transaction Cost # Shares Value($) Total Shares Form 4
IOBT 10% Owner Nov 09, 2021 Buy $14.00 325,000 4,550,000 2,690,545 Nov 12, 2021, 04:16 PM
NBRV 10% Owner Sep 14, 2017 Sale $8.52 3,429 29,224 2,334,128 Sep 14, 2017, 08:21 PM
NBRV 10% Owner Sep 13, 2017 Sale $8.54 22,721 193,956 2,337,557 Sep 14, 2017, 08:21 PM
NBRV 10% Owner Sep 12, 2017 Sale $8.63 10,458 90,236 2,360,278 Sep 14, 2017, 08:21 PM
NBRV 10% Owner Aug 31, 2017 Sale $9.50 639 6,071 2,370,735 Sep 05, 2017, 08:18 PM
NBRV 10% Owner Aug 08, 2017 Sale $10.50 2,013 21,137 2,371,374 Aug 09, 2017, 08:54 PM
NBRV 10% Owner Aug 07, 2017 Sale $10.50 17,790 186,795 2,373,387 Aug 09, 2017, 08:54 PM
NBRV 10% Owner Jul 28, 2017 Sale $10.51 6,585 69,195 2,391,177 Aug 01, 2017, 09:21 PM
NBRV 10% Owner Jul 24, 2017 Sale $10.50 160 1,680 2,397,762 Jul 26, 2017, 09:03 PM
NBRV 10% Owner Jul 20, 2017 Sale $10.50 23,445 246,173 2,397,922 Jul 24, 2017, 09:10 PM
NBRV 10% Owner Jul 19, 2017 Sale $10.50 20,786 218,253 2,421,367 Jul 24, 2017, 09:10 PM
NBRV 10% Owner Jul 20, 2017 Sale $10.50 23,445 246,173 2,397,922 Jul 21, 2017, 09:36 PM
NBRV 10% Owner Jul 19, 2017 Sale $10.50 20,786 218,253 2,421,367 Jul 21, 2017, 09:36 PM
NBRV 10% Owner Jul 18, 2017 Sale $10.50 1,339 14,060 2,442,153 Jul 18, 2017, 09:03 PM
NBRV 10% Owner Jul 17, 2017 Sale $10.50 47,460 498,415 2,443,492 Jul 18, 2017, 09:03 PM
NBRV 10% Owner Jul 14, 2017 Sale $10.53 21,055 221,789 2,490,952 Jul 18, 2017, 09:03 PM
NBRV 10% Owner Jul 13, 2017 Sale $10.54 39,914 420,757 2,512,007 Jul 13, 2017, 09:22 PM
NBRV 10% Owner Jul 12, 2017 Sale $10.50 13,740 144,271 2,551,921 Jul 13, 2017, 09:22 PM
NBRV 10% Owner Jul 11, 2017 Sale $10.52 3,521 37,027 2,565,661 Jul 13, 2017, 09:22 PM
NBRV 10% Owner Jul 07, 2017 Sale $10.50 133 1,397 2,569,182 Jul 07, 2017, 09:29 PM
NBRV 10% Owner Jul 05, 2017 Sale $10.52 2,562 26,960 2,569,315 Jul 07, 2017, 09:29 PM
NBRV 10% Owner Jul 03, 2017 Sale $10.95 11,352 124,250 2,571,877 Jul 05, 2017, 08:58 PM
NBRV 10% Owner Jun 30, 2017 Sale $10.94 1,775 19,420 2,583,229 Jul 05, 2017, 08:58 PM
NBRV 10% Owner Jun 29, 2017 Sale $10.72 1,603 17,189 2,585,004 Jun 29, 2017, 09:33 PM
NBRV 10% Owner Jun 28, 2017 Sale $11.10 4,789 53,158 2,586,697 Jun 29, 2017, 09:33 PM
NBRV 10% Owner Jun 27, 2017 Sale $10.83 2,166 23,457 2,591,396 Jun 29, 2017, 09:33 PM
NBRV 10% Owner Jun 01, 2017 Sale $11.27 400 4,508 2,593,562 Jun 05, 2017, 09:41 PM
NBRV 10% Owner Apr 28, 2017 Sale $11.03 15,130 166,813 2,593,962 Apr 28, 2017, 07:13 PM
NBRV 10% Owner Apr 27, 2017 Sale $11.00 100 1,100 2,609,092 Apr 28, 2017, 07:13 PM
NBRV 10% Owner Apr 26, 2017 Sale $11.00 709 7,799 2,609,192 Apr 28, 2017, 07:13 PM
NBRV 10% Owner Apr 21, 2017 Sale $11.04 2,622 28,937 2,609,901 Apr 25, 2017, 07:19 PM
NBRV 10% Owner Apr 19, 2017 Sale $11.07 11,785 130,434 2,612,848 Apr 20, 2017, 08:29 PM
NBRV 10% Owner Apr 18, 2017 Sale $11.16 11,822 131,880 2,624,633 Apr 20, 2017, 08:29 PM
NBRV 10% Owner Apr 20, 2017 Sale $11.00 325 3,575 2,612,523 Apr 20, 2017, 08:29 PM
NBRV 10% Owner Apr 13, 2017 Sale $11.13 10,984 122,232 2,636,455 Apr 13, 2017, 09:12 PM
NBRV 10% Owner Apr 12, 2017 Sale $11.22 13,250 148,653 2,647,439 Apr 13, 2017, 09:12 PM
NBRV 10% Owner Apr 11, 2017 Sale $11.40 8,597 98,034 2,660,689 Apr 13, 2017, 09:12 PM
NBRV 10% Owner Apr 10, 2017 Sale $10.73 37,876 406,451 2,669,286 Apr 11, 2017, 06:04 AM
NBRV 10% Owner Apr 07, 2017 Sale $10.97 21,501 235,931 2,725,163 Apr 11, 2017, 06:04 AM
NBRV 10% Owner Apr 06, 2017 Sale $11.22 31,217 350,160 2,753,263 Apr 11, 2017, 06:04 AM
NBRV 10% Owner Apr 10, 2017 Sale $10.73 37,876 406,451 185,394 Apr 10, 2017, 09:38 PM
NBRV 10% Owner Apr 07, 2017 Sale $10.97 21,501 235,931 241,271 Apr 10, 2017, 09:38 PM
NBRV 10% Owner Apr 06, 2017 Sale $11.22 31,217 350,160 269,371 Apr 10, 2017, 09:38 PM
PRTK 10% Owner May 29, 2015 Sale $29.79 10,000 297,908 1,751,380 Jun 01, 2015, 08:36 PM
PRTK 10% Owner May 28, 2015 Sale $31.66 10,580 334,985 1,760,045 Jun 01, 2015, 08:36 PM
OPHT 10% Owner May 13, 2014 Sale $29.75 500,000 14,875,000 3,139,902 May 15, 2014, 05:10 PM
PTCT 10% Owner Dec 17, 2013 Sale $19.08 66,667 1,272,120 2,441,504 Dec 19, 2013, 04:42 PM
OPHT 10% Owner Sep 30, 2013 Buy $22.00 228,000 5,016,000 3,639,902 Oct 03, 2013, 05:51 PM
PTCT 10% Owner Jun 25, 2013 Buy $15.00 666,676 10,000,140 2,508,171 Jun 28, 2013, 01:36 PM
PCRX 10% Owner Mar 22, 2013 Sale $27.52 113,928 3,135,595 2,399,534 Mar 25, 2013, 08:10 PM
PCRX 10% Owner Mar 21, 2013 Sale $27.50 11,431 314,353 2,513,462 Mar 25, 2013, 08:10 PM
PCRX 10% Owner Mar 25, 2013 Sale $28.28 165,541 4,680,738 2,233,993 Mar 25, 2013, 08:10 PM
PCRX 10% Owner Mar 19, 2013 Sale $27.86 9,100 253,501 2,524,893 Mar 21, 2013, 09:52 PM
PCRX 10% Owner Mar 18, 2013 Sale $28.19 400,000 11,277,480 2,533,993 Mar 21, 2013, 09:52 PM
PCRX 10% Owner Mar 11, 2013 Sale $27.86 500,000 13,930,000 2,933,993 Mar 21, 2013, 09:52 PM
PCRX 10% Owner Nov 21, 2011 Buy $6.50 307,692 1,999,998 3,445,289 Nov 22, 2011, 06:48 PM
PCRX 10% Owner Feb 08, 2011 Option Exercise $13.44 1,021,223 13,725,237 2,601,883 Feb 10, 2011, 08:35 PM
PCRX 10% Owner Feb 08, 2011 Buy $7.00 535,714 3,749,998 3,137,597 Feb 10, 2011, 08:35 PM

Desktop Version

Symbol Relationship Date Transaction Value($)
IOBT 10% Owner Nov 09, 2021 Buy 4,550,000
NBRV 10% Owner Sep 14, 2017 Sale 29,224
NBRV 10% Owner Sep 13, 2017 Sale 193,956
NBRV 10% Owner Sep 12, 2017 Sale 90,236
NBRV 10% Owner Aug 31, 2017 Sale 6,071
NBRV 10% Owner Aug 08, 2017 Sale 21,137
NBRV 10% Owner Aug 07, 2017 Sale 186,795
NBRV 10% Owner Jul 28, 2017 Sale 69,195
NBRV 10% Owner Jul 24, 2017 Sale 1,680
NBRV 10% Owner Jul 20, 2017 Sale 246,173
NBRV 10% Owner Jul 19, 2017 Sale 218,253
NBRV 10% Owner Jul 20, 2017 Sale 246,173
NBRV 10% Owner Jul 19, 2017 Sale 218,253
NBRV 10% Owner Jul 18, 2017 Sale 14,060
NBRV 10% Owner Jul 17, 2017 Sale 498,415
NBRV 10% Owner Jul 14, 2017 Sale 221,789
NBRV 10% Owner Jul 13, 2017 Sale 420,757
NBRV 10% Owner Jul 12, 2017 Sale 144,271
NBRV 10% Owner Jul 11, 2017 Sale 37,027
NBRV 10% Owner Jul 07, 2017 Sale 1,397
NBRV 10% Owner Jul 05, 2017 Sale 26,960
NBRV 10% Owner Jul 03, 2017 Sale 124,250
NBRV 10% Owner Jun 30, 2017 Sale 19,420
NBRV 10% Owner Jun 29, 2017 Sale 17,189
NBRV 10% Owner Jun 28, 2017 Sale 53,158
NBRV 10% Owner Jun 27, 2017 Sale 23,457
NBRV 10% Owner Jun 01, 2017 Sale 4,508
NBRV 10% Owner Apr 28, 2017 Sale 166,813
NBRV 10% Owner Apr 27, 2017 Sale 1,100
NBRV 10% Owner Apr 26, 2017 Sale 7,799
NBRV 10% Owner Apr 21, 2017 Sale 28,937
NBRV 10% Owner Apr 19, 2017 Sale 130,434
NBRV 10% Owner Apr 18, 2017 Sale 131,880
NBRV 10% Owner Apr 20, 2017 Sale 3,575
NBRV 10% Owner Apr 13, 2017 Sale 122,232
NBRV 10% Owner Apr 12, 2017 Sale 148,653
NBRV 10% Owner Apr 11, 2017 Sale 98,034
NBRV 10% Owner Apr 10, 2017 Sale 406,451
NBRV 10% Owner Apr 07, 2017 Sale 235,931
NBRV 10% Owner Apr 06, 2017 Sale 350,160
NBRV 10% Owner Apr 10, 2017 Sale 406,451
NBRV 10% Owner Apr 07, 2017 Sale 235,931
NBRV 10% Owner Apr 06, 2017 Sale 350,160
PRTK 10% Owner May 29, 2015 Sale 297,908
PRTK 10% Owner May 28, 2015 Sale 334,985
OPHT 10% Owner May 13, 2014 Sale 14,875,000
PTCT 10% Owner Dec 17, 2013 Sale 1,272,120
OPHT 10% Owner Sep 30, 2013 Buy 5,016,000
PTCT 10% Owner Jun 25, 2013 Buy 10,000,140
PCRX 10% Owner Mar 22, 2013 Sale 3,135,595
PCRX 10% Owner Mar 21, 2013 Sale 314,353
PCRX 10% Owner Mar 25, 2013 Sale 4,680,738
PCRX 10% Owner Mar 19, 2013 Sale 253,501
PCRX 10% Owner Mar 18, 2013 Sale 11,277,480
PCRX 10% Owner Mar 11, 2013 Sale 13,930,000
PCRX 10% Owner Nov 21, 2011 Buy 1,999,998
PCRX 10% Owner Feb 08, 2011 Option Exercise 13,725,237
PCRX 10% Owner Feb 08, 2011 Buy 3,749,998