| Symbol | Relationship | Date | Transaction | Cost | # Shares | Value($) | Total Shares | Form 4 |
| SUPN | Director | Feb 21, 2020 | Option Exercise | $23.99 | 5,211 | 125,012 | 97,509 | Feb 25, 2020, 05:59 PM |
| FIO | 10% Owner | Aug 13, 2012 | Sale | $25.87 | 2,622 | 67,838 | 0 | Aug 14, 2012, 03:12 PM |
| HPTX | 10% Owner | Jul 31, 2012 | Buy | $10.00 | 500,000 | 5,000,000 | 2,884,221 | Aug 02, 2012, 02:12 PM |
| SUPN | Director | May 04, 2012 | Buy | $5.00 | 4,400,000 | 22,000,000 | 10,641,250 | May 08, 2012, 04:34 PM |
| FOLD | 10% Owner | Mar 07, 2012 | Buy | $5.70 | 925,154 | 5,273,378 | 4,584,311 | Mar 09, 2012, 03:52 PM |
| FOLD | 10% Owner | Mar 07, 2012 | Buy | $5.70 | 214,846 | 1,224,622 | 1,066,029 | Mar 09, 2012, 03:52 PM |
| INWK | 10% Owner | Feb 29, 2012 | Sale | $11.42 | 455,360 | 5,199,164 | 6,029,190 | Mar 01, 2012, 04:36 PM |
| INWK | 10% Owner | Feb 24, 2012 | Sale | $11.40 | 334,457 | 3,812,810 | 6,484,550 | Feb 28, 2012, 12:06 PM |
| INWK | 10% Owner | Feb 23, 2012 | Sale | $11.75 | 54,849 | 644,344 | 6,819,007 | Feb 24, 2012, 12:14 PM |
| INWK | 10% Owner | Feb 22, 2012 | Sale | $11.68 | 253,211 | 2,957,808 | 6,873,856 | Feb 24, 2012, 12:14 PM |
| INHX | 10% Owner | Feb 13, 2012 | Option Exercise | $26.00 | 2,190,271 | 56,947,046 | 0 | Feb 15, 2012, 07:46 PM |
| INHX | 10% Owner | Feb 13, 2012 | Option Exercise | $26.00 | 7,644,890 | 198,767,140 | 0 | Feb 15, 2012, 07:46 PM |
| FIO | 10% Owner | Nov 28, 2011 | Sale | $31.68 | 1,291,493 | 40,914,499 | 24,538,379 | Nov 30, 2011, 03:05 PM |
| GLUU | 10% Owner | Aug 08, 2011 | Option Exercise | $1.50 | 375,000 | 562,500 | 5,919,443 | Aug 09, 2011, 03:06 PM |
| ARYX | 10% Owner | Mar 10, 2011 | Sale | $0.07 | 4,469,274 | 326,257 | 0 | Mar 14, 2011, 01:59 PM |
| GLUU | 10% Owner | Aug 27, 2010 | Buy | $1.00 | 750,000 | 750,000 | 5,544,443 | Aug 31, 2010, 04:02 PM |
| Symbol | Relationship | Date | Transaction | Value($) |
| SUPN | Director | Feb 21, 2020 | Option Exercise | 125,012 |
| FIO | 10% Owner | Aug 13, 2012 | Sale | 67,838 |
| HPTX | 10% Owner | Jul 31, 2012 | Buy | 5,000,000 |
| SUPN | Director | May 04, 2012 | Buy | 22,000,000 |
| FOLD | 10% Owner | Mar 07, 2012 | Buy | 5,273,378 |
| FOLD | 10% Owner | Mar 07, 2012 | Buy | 1,224,622 |
| INWK | 10% Owner | Feb 29, 2012 | Sale | 5,199,164 |
| INWK | 10% Owner | Feb 24, 2012 | Sale | 3,812,810 |
| INWK | 10% Owner | Feb 23, 2012 | Sale | 644,344 |
| INWK | 10% Owner | Feb 22, 2012 | Sale | 2,957,808 |
| INHX | 10% Owner | Feb 13, 2012 | Option Exercise | 56,947,046 |
| INHX | 10% Owner | Feb 13, 2012 | Option Exercise | 198,767,140 |
| FIO | 10% Owner | Nov 28, 2011 | Sale | 40,914,499 |
| GLUU | 10% Owner | Aug 08, 2011 | Option Exercise | 562,500 |
| ARYX | 10% Owner | Mar 10, 2011 | Sale | 326,257 |
| GLUU | 10% Owner | Aug 27, 2010 | Buy | 750,000 |