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| Stock | Company | % Portfolio | Shares Held | Market Value | Change in Shares | % Change | Quarter End Price | Source |
|---|---|---|---|---|---|---|---|---|
| ASND | ASCENDIS PHARMA A/S | 18.46% | 11,225,357 | $1,001,863,112 | 4,268,178 | 61.35% | $89.25 | 13F |
| LEGN | LEGEND BIOTECH CORP | 7.97% | 6,264,707 | $432,452,724 | 3,828,484 | 157.15% | $69.03 | 13F |
| PCVX | VAXCYTE INC | 7.26% | 7,891,254 | $394,089,225 | 600,000 | 8.23% | $49.94 | 13F |
| ETNB | 89bio, Inc. | 3.67% | 12,874,814 | $204,580,794 | 1,457,866 | 12.77% | 13D | |
| GRCL | Gracell Biotechnologies Inc. | 3.25% | 48,600,300 | $182,251,125 | 48,600,300 | New | 13G | |
| BIIB | BIOGEN INC | 2.80% | 532,892 | $151,794,286 | No Change | $284.85 | 13F | |
| AVTE | AEROVATE THERAPEUTICS INC | 2.61% | 8,263,982 | $141,727,291 | No Change | $17.15 | 13F | |
| VRNA | VERONA PHARMA PLC | 2.46% | 6,317,990 | $133,562,309 | No Change | $21.14 | 13F | |
| CVAC | CUREVAC N V | 2.35% | 12,245,955 | $127,602,851 | No Change | $10.42 | 13F | |
| CBAY | CymaBay Therapeutics, Inc. | 2.27% | 6,940,000 | $122,282,800 | 6,940,000 | New | 13G | |
| TYRA | TYRA BIOSCIENCES INC | 2.27% | 7,236,454 | $123,236,812 | No Change | $17.03 | 13F | |
| ABOS | Acumen Pharmaceuticals, Inc. | 2.14% | 14,932,063 | $115,723,488 | 5,161,290 | 52.82% | Form 4 | |
| JANX | Janux Therapeutics, Inc. | 2.10% | 9,165,652 | $114,204,024 | 495,008 | 5.71% | Form 4 | |
| NAMS | NEWAMSTERDAM PHARMA COMPANY | 1.97% | 9,000,000 | $107,010,000 | 5,000,000 | 125% | $11.89 | 13F |
| GERN | GERON CORP | 1.87% | 31,544,806 | $101,258,827 | No Change | $3.21 | 13F | |
| INBX | INHIBRX INC | 1.84% | 3,853,867 | $100,046,387 | No Change | $25.96 | 13F | |
| DAWN | DAY ONE BIOPHARMACEUTICALS I | 1.72% | 7,809,852 | $93,249,633 | 769,230 | 10.93% | $11.94 | 13F |
| RYTM | RHYTHM PHARMACEUTICALS INC | 1.72% | 5,676,067 | $93,598,345 | 160,000 | 2.9% | $16.49 | 13F |
| RXST | RXSIGHT INC | 1.62% | 3,052,796 | $87,920,525 | No Change | $28.8 | 13F | |
| COGT | COGENT COMMUNICATIONS HLDGS | 1.40% | 6,416,147 | $75,967,180 | 416,666 | 6.95% | $11.84 | 13F |
| PEPG | PEPGEN INC | 1.34% | 8,131,952 | $72,699,651 | No Change | $8.94 | 13F | |
| AXSM | AXSOME THERAPEUTICS INC | 1.32% | 1,000,000 | $71,860,000 | 1,000,000 | New | $71.86 | 13F |
| RNA | AVIDITY BIOSCIENCES INC | 1.31% | 6,416,998 | $71,164,508 | No Change | $11.09 | 13F | |
| GHRS | GH RESEARCH PLC | 1.22% | 5,587,333 | $66,293,706 | 6,172 | 0.11% | $11.86 | 13F |
| ACRV | ACRIVON THERAPEUTICS INC | 1.15% | 4,810,508 | $62,344,184 | No Change | $12.96 | 13F | |
| WVE | WAVE LIFE SCIENCES LTD | 1.15% | 17,202,009 | $62,615,313 | No Change | $3.64 | 13F | |
| ICVX | ICOSAVAX INC | 1.09% | 5,963,565 | $59,218,200 | No Change | $9.93 | 13F | |
| ITOS | ITEOS THERAPEUTICS INC | 1.08% | 4,417,259 | $58,484,509 | No Change | $13.24 | 13F | |
| VOR | Vor Biopharma Inc. | 1.05% | 22,780,343 | $58,545,482 | 31,463 | 0.14% | 13D | |
| FDMT | 4D MOLECULAR THERAPEUTICS IN | 1.02% | 3,069,531 | $55,466,425 | 3,069,531 | New | $18.07 | 13F |
| SPRY | ARS Pharmaceuticals, Inc. | 1.01% | 17,825,143 | $54,010,183 | 14,815,465 | 492.26% | Form 4 | |
| MLYS | MINERALYS THERAPEUTICS INC | 1.00% | 3,178,476 | $54,193,016 | No Change | $17.05 | 13F | |
| ANTX | AN2 Therapeutics, Inc. | 0.93% | 5,551,295 | $49,961,655 | 1,777,778 | 47.11% | Form 4 | |
| CTKB | Cytek Biosciences, Inc. | 0.91% | 6,809,404 | $47,665,828 | -5,488,317 | -44.63% | 13D | |
| ALPN | ALPINE IMMUNE SCIENCES INC | 0.89% | 4,691,178 | $48,225,310 | 3,063 | 0.07% | $10.28 | 13F |
| VRDN | VIRIDIAN THERAPEUTICS INC | 0.88% | 2,007,946 | $47,769,035 | No Change | $23.79 | 13F | |
| ACRS | ACLARIS THERAPEUTICS INC | 0.84% | 4,398,453 | $45,611,958 | No Change | $10.37 | 13F | |
| IMGN | IMMUNOGEN INC | 0.81% | 2,329,958 | $43,966,307 | -19,524,000 | -89.34% | $18.87 | 13F |
| ELVN | ENLIVEN THERAPEUTICS INC | 0.80% | 2,122,465 | $43,319,511 | No Change | $20.41 | 13F | |
| FULC | FULCRUM THERAPEUTICS INC | 0.71% | 11,609,704 | $38,312,023 | No Change | $3.3 | 13F | |
| ELYM | ELIEM THERAPEUTICS INC | 0.68% | 13,150,849 | $36,822,377 | No Change | $2.8 | 13F | |
| TSHA | Taysha Gene Therapies, Inc. | 0.67% | 18,690,868 | $36,073,375 | 18,690,868 | New | 13G | |
| TNYA | TENAYA THERAPEUTICS INC | 0.66% | 6,067,483 | $35,616,125 | No Change | $5.87 | 13F | |
| PLRX | PLIANT THERAPEUTICS INC | 0.59% | 1,762,000 | $31,927,440 | No Change | $18.12 | 13F | |
| EYPT | EYEPOINT PHARMACEUTICALS INC | 0.54% | 3,370,506 | $29,323,402 | No Change | $8.7 | 13F | |
| NKTR | NEKTAR THERAPEUTICS | 0.36% | 18,700,000 | $19,074,000 | 18,700,000 | New | 13G | |
| HOWL | WEREWOLF THERAPEUTICS INC | 0.35% | 6,144,881 | $18,741,887 | No Change | $3.05 | 13F | |
| DSGN | DESIGN THERAPEUTICS INC | 0.34% | 2,971,231 | $18,718,755 | No Change | $6.3 | 13F | |
| SLDB | SOLID BIOSCIENCES INC | 0.33% | 3,426,286 | $17,953,739 | No Change | $5.24 | 13F | |
| BDTX | Black Diamond Therapeutics, Inc. | 0.32% | 3,525,754 | $17,628,770 | No Change | Form 4 | ||
| NKTX | NKARTA INC | 0.31% | 7,805,129 | $17,093,233 | No Change | $2.19 | 13F | |
| CELC | CELCUITY INC | 0.28% | 1,400,001 | $15,372,011 | No Change | $10.98 | 13F | |
| IGMS | IGM BIOSCIENCES INC | 0.16% | 937,500 | $8,653,125 | 937,500 | New | $9.23 | 13F |
| CNTB | CONNECT BIOPHARMA HLDGS LTD | 0.15% | 6,991,003 | $7,899,833 | No Change | $1.13 | 13F | |
| CMRX | CHIMERIX INC | 0.13% | 6,501,624 | $6,891,721 | 6,501,624 | New | 13G | |
| NSTG | NANOSTRING TECHNOLOGIES | 0.13% | 1,723,373 | $6,979,661 | -733,900 | -29.87% | $4.05 | 13F |
| TALS | TALARIS THERAPEUTICS INC | 0.13% | 2,333,175 | $7,092,852 | 2,333,175 | New | $3.04 | 13F |
| NAMSW | NEWAMSTERDAM PHARMA COMPANY | 0.01% | 333,333 | $696,666 | No Change | $2.09 | 13F | |
| AADI | AADI BIOSCIENCE INC | -590,218 | Exited | 13F | ||||
| BLU | BELLUS HEALTH INC NEW | -12,643,574 | Exited | 13F | ||||
| CLDX | CELLDEX THERAPEUTICS INC NEW | -1,734,972 | Exited | 13F | ||||
| DICE | DICE Therapeutics, Inc. | -7,856,612 | Exited | 13D | ||||
| FUSN | FUSION PHARMACEUTICALS INC | -659,992 | Exited | 13F | ||||
| HLVX | HILLEVAX INC | -1,760,019 | Exited | 13F | ||||
| KNTE | KINNATE BIOPHARMA INC | -4,264,144 | Exited | 13F | ||||
| RCKT | ROCKET PHARMACEUTICALS INC | -1,131,775 | Exited | 13F | ||||
| STSA | SATSUMA PHARMACEUTICALS INC | -5,914,252 | Exited | 13F | ||||
| ENTX | ENTERA BIO LTD | -295,966 | Exited | 13F |
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