| Stock | Company | % Portfolio | Shares Held | Market Value | Change in Shares | % Change | Quarter End Price | Source |
|---|---|---|---|---|---|---|---|---|
| INSM | INSMED INC | 17.15% | 1,603,465 | $110,703,224 | -337,528 | -17.39% | $69.04 | 13F |
| FOLD | AMICUS THERAPEUTICS INC | 11.18% | 7,662,479 | $72,180,552 | -482,832 | -5.93% | $9.42 | 13F |
| BMRN | BIOMARIN PHARMACEUTICAL INC | 10.87% | 1,067,266 | $70,151,394 | -22,790 | -2.09% | $65.73 | 13F |
| UTHR | UNITED THERAPEUTICS CORP | 8.51% | 155,714 | $54,942,128 | -27,532 | -15.02% | $352.84 | 13F |
| ACAD | ACADIA PHARMACEUTICALS INC | 7.82% | 2,748,599 | $50,436,792 | 224,643 | 8.9% | $18.35 | 13F |
| ALNY | ALNYLAM PHARMACEUTICALS INC | 5.13% | 140,681 | $33,103,646 | No Change | $235.31 | 13F | |
| BIIB | BIOGEN INC | 4.51% | 190,148 | $29,077,432 | -38,768 | -16.94% | $152.92 | 13F |
| SRPT | SAREPTA THERAPEUTICS INC | 3.96% | 210,258 | $25,565,270 | No Change | $121.59 | 13F | |
| NVCR | NOVOCURE LTD | 3.76% | 814,191 | $24,262,892 | 220,651 | 37.18% | $29.8 | 13F |
| PRTA | PROTHENA CORP PLC | 3.73% | 1,737,964 | $24,070,801 | No Change | $13.85 | 13F | |
| IOVA | IOVANCE BIOTHERAPEUTICS INC | 3.49% | 3,041,685 | $22,508,469 | No Change | $7.4 | 13F | |
| EHTH | EHEALTH INC | 2.74% | 1,878,127 | $17,654,394 | -469,392 | -20% | $9.4 | 13F |
| PTCT | PTC THERAPEUTICS INC | 2.7% | 386,413 | $17,442,683 | 121,944 | 46.11% | $45.14 | 13F |
| STAA | STAAR SURGICAL CO | 1.88% | 500,775 | $12,163,825 | -590,833 | -54.13% | $24.29 | 13F |
| ANAB | ANAPTYSBIO INC | 1.73% | 843,971 | $11,174,176 | No Change | $13.24 | 13F | |
| ALKS | ALKERMES PLC | 1.29% | 289,308 | $8,320,498 | -95,348 | -24.79% | $28.76 | 13F |
| ALGN | ALIGN TECHNOLOGY INC | 1.22% | 37,772 | $7,875,840 | No Change | $208.51 | 13F | |
| GOSS | GOSSAMER BIO INC | 0.88% | 6,277,093 | $5,678,258 | No Change | $0.9 | 13F | |
| SLRN | ACELYRIN INC | 0.87% | 1,792,895 | $5,629,690 | No Change | $3.14 | 13F | |
| SNDX | SYNDAX PHARMACEUTICALS INC | 0.83% | 405,193 | $5,356,651 | No Change | $13.22 | 13F | |
| BCYC | BICYCLE THERAPEUTICS PLC-ADR | 0.54% | 248,934 | $3,485,076 | 189,352 | 317.8% | $14 | 13F |
| KPTI | KARYOPHARM THERAPEUTICS INC | 0.51% | 4,907,001 | $3,318,605 | -195,192 | -3.83% | $0.68 | 13F |
| VERV | VERVE THERAPEUTICS INC | 0.5% | 575,817 | $3,247,608 | No Change | $5.64 | 13F | |
| BNTX | BIONTECH SE-ADR | 0.45% | 25,206 | $2,872,224 | No Change | $113.95 | 13F | |
| EW | EDWARDS LIFESCIENCES CORP | 0.45% | 39,473 | $2,922,186 | No Change | $74.03 | 13F | |
| NVRO | NEVRO CORP | 0.43% | 750,371 | $2,791,380 | No Change | $3.72 | 13F | |
| MIRM | MIRUM PHARMACEUTICALS INC | 0.41% | 64,700 | $2,675,345 | No Change | $41.35 | 13F | |
| NUVB | NUVATION BIO INC | 0.32% | 772,652 | $2,055,254 | No Change | $2.66 | 13F | |
| TVTX | TRAVERE THERAPEUTICS INC | 0.3% | 110,719 | $1,928,725 | No Change | $17.42 | 13F | |
| PYXS | PYXIS ONCOLOGY INC | 0.25% | 1,037,421 | $1,618,377 | 867,421 | 510.25% | $1.56 | 13F |
| VYNE | VYNE THERAPEUTICS INC PIPE | 0.23% | 445,434 | $1,492,204 | No Change | $3.35 | 13F | |
| ACRS | ACLARIS THERAPEUTICS INC | 0.22% | 569,832 | $1,413,183 | No Change | $2.48 | 13F | |
| STOK | STOKE THERAPEUTICS INC | 0.22% | 125,861 | $1,388,247 | No Change | $11.03 | 13F | |
| TSHA | TAYSHA GENE THERAPIES INC | 0.22% | 811,268 | $1,403,494 | No Change | $1.73 | 13F | |
| ALDX | ALDEYRA THERAPEUTICS INC | 0.17% | 225,465 | $1,125,070 | No Change | $4.99 | 13F | |
| HUM | HUMANA INC | 0.16% | 3,985 | $1,011,034 | No Change | $253.71 | 13F | |
| JSPR | JASPER THERAPEUTICS INC | 0.1% | 30,651 | $655,318 | 30,651 | New | $21.38 | 13F |
| ABEO | ABEONA THERAPEUTICS INC | 0.09% | 108,865 | $606,378 | 96,000 | 746.21% | $5.57 | 13F |
| RLMD | RELMADA THERAPEUTICS INC | 0.04% | 495,146 | $257,476 | -237,254 | -32.39% | $0.52 | 13F |
| URGN | UROGEN PHARMA LTD | 0.04% | 24,500 | $260,925 | No Change | $10.65 | 13F | |
| AKTX | AKARI THERAPEUTICS PLC-ADR | 0.03% | 146,024 | $178,149 | 146,024 | New | $1.22 | 13F |
| TIL | INSTIL BIO INC | 0.03% | 11,165 | $213,140 | No Change | $19.09 | 13F | |
| GBIO | GENERATION BIO CO | 0.02% | 150,475 | $159,504 | No Change | $1.06 | 13F | |
| BLUE | BLUEBIRD BIO INC | -604,260 | Exited | 13F | ||||
| ELEV | ELEVATION ONCOLOGY INC | -1,298,097 | Exited | 13F | ||||
| RVNC | REVANCE THERAPEUTICS INC | -1,611,787 | Exited | 13F | ||||
| SAGE | SAGE THERAPEUTICS INC | -1,010,833 | Exited | 13F |