| SPY | SPDR S&P 500 ETF TR (Put) | 12.33% | 4,150,000 | $2,432,232,000 | -1,162,500 | -21.88% | $586.08 | 13F |
| EXEL | EXELIXIS INC | 3.96% | 23,439,500 | $780,535,350 | -1,971,000 | -7.76% | $33.3 | 13F |
| RSP | INVESCO EXCHANGE TRADED FD T (Put) | 3.91% | 4,400,000 | $771,012,000 | | No Change | $175.23 | 13F |
| UNH | UNITEDHEALTH GROUP INC | 3.75% | 1,462,500 | $739,820,250 | 364,600 | 33.21% | $505.86 | 13F |
| NTRA | NATERA INC | 3.56% | 4,431,609 | $701,523,705 | -125,700 | -2.76% | $158.3 | 13F |
| MSFT | MICROSOFT CORP | 3.49% | 1,633,147 | $688,371,461 | 166,400 | 11.34% | $421.5 | 13F |
| AON | AON PLC | 3.34% | 1,832,733 | $658,244,384 | 126,733 | 7.43% | $359.16 | 13F |
| TMO | THERMO FISHER SCIENTIFIC INC | 3.25% | 1,233,256 | $641,576,769 | 523,800 | 73.83% | $520.23 | 13F |
| IQV | IQVIA HLDGS INC | 3.11% | 3,123,151 | $613,730,403 | -47,932 | -1.51% | $196.51 | 13F |
| RVMD | REVOLUTION MEDICINES INC | 2.94% | 13,248,692 | $579,497,788 | 1,931,000 | 17.06% | $43.74 | 13F |
| ADSK | AUTODESK INC | 2.76% | 1,841,800 | $544,380,826 | 1,841,800 | New | $295.57 | 13F |
| DIS | DISNEY WALT CO | 2.5% | 4,428,068 | $493,065,372 | -1,401,500 | -24.04% | $111.35 | 13F |
| TRU | TRANSUNION | 2.5% | 5,326,319 | $493,803,034 | -149,000 | -2.72% | $92.71 | 13F |
| IBB | ISHARES TR (Put) | 2.41% | 3,600,000 | $475,956,000 | 1,600,000 | 80% | $132.21 | 13F |
| LNTH | LANTHEUS HLDGS INC | 2.41% | 5,316,227 | $475,589,667 | 2,361,000 | 79.89% | $89.46 | 13F |
| INTU | INTUIT | 2.4% | 753,758 | $473,736,903 | 123,061 | 19.51% | $628.5 | 13F |
| BSX | BOSTON SCIENTIFIC CORP | 2.28% | 5,022,957 | $448,650,519 | -402,700 | -7.42% | $89.32 | 13F |
| ARMK | ARAMARK | 2.16% | 11,410,340 | $425,719,785 | -226,597 | -1.95% | $37.31 | 13F |
| CRM | SALESFORCE INC | 2.05% | 1,210,138 | $404,585,438 | -834,800 | -40.82% | $334.33 | 13F |
| GOOG | ALPHABET INC | 2.01% | 2,080,540 | $396,218,038 | -330,000 | -13.69% | $190.44 | 13F |
| IBIT | ISHARES BITCOIN TRUST ETF | 1.95% | 7,259,100 | $385,095,255 | 5,819,100 | 404.1% | $53.05 | 13F |
| NYT | NEW YORK TIMES CO | 1.95% | 7,376,113 | $383,926,682 | -1,368,733 | -15.65% | $52.05 | 13F |
| MCK | MCKESSON CORP | 1.77% | 610,700 | $348,044,037 | 610,700 | New | $569.91 | 13F |
| SRPT | SAREPTA THERAPEUTICS INC | 1.77% | 2,865,100 | $348,367,509 | 285,100 | 11.05% | $121.59 | 13F |
| ABNB | AIRBNB INC | 1.62% | 2,429,200 | $319,221,172 | 58,000 | 2.45% | $131.41 | 13F |
| NDAQ | NASDAQ INC | 1.57% | 3,998,019 | $309,086,849 | 235,748 | 6.27% | $77.31 | 13F |
| CBRE | CBRE GROUP INC | 1.45% | 2,179,800 | $286,185,942 | -790,600 | -26.62% | $131.29 | 13F |
| WAB | WABTEC | 1.38% | 1,430,198 | $271,151,239 | -781,200 | -35.33% | $189.59 | 13F |
| WWD | WOODWARD INC | 1.28% | 1,521,300 | $253,174,746 | 367,300 | 31.83% | $166.42 | 13F |
| ADI | ANALOG DEVICES INC | 1.25% | 1,157,200 | $245,858,712 | -314,900 | -21.39% | $212.46 | 13F |
| SCHW | SCHWAB CHARLES CORP | 1.19% | 3,169,000 | $234,537,690 | 3,169,000 | New | $74.01 | 13F |
| PTGX | PROTAGONIST THERAPEUTICS INC | 1.16% | 5,930,006 | $228,898,232 | 69,000 | 1.18% | $38.6 | 13F |
| CRNX | CRINETICS PHARMACEUTICALS IN | 1.06% | 4,075,098 | $208,359,761 | 2,913,098 | 250.7% | $51.13 | 13F |
| BEAM | BEAM THERAPEUTICS INC | 1.04% | 8,239,123 | $204,330,250 | 31,000 | 0.38% | $24.8 | 13F |
| HIMS | HIMS & HERS HEALTH INC | 1.03% | 8,377,000 | $202,555,860 | 8,364,000 | 64338.5% | $24.18 | 13F |
| AGIO | AGIOS PHARMACEUTICALS INC | 0.95% | 5,674,466 | $186,462,953 | 13,600 | 0.24% | $32.86 | 13F |
| BMY | BRISTOL-MYERS SQUIBB CO | 0.91% | 3,188,000 | $180,313,280 | 3,188,000 | New | $56.56 | 13F |
| YMM | FULL TRUCK ALLIANCE CO LTD | 0.91% | 16,585,095 | $179,450,728 | -4,080,453 | -19.75% | $10.82 | 13F |
| V | VISA INC | 0.88% | 549,510 | $173,667,140 | -202,500 | -26.93% | $316.04 | 13F |
| BHVN | BIOHAVEN LTD | 0.84% | 4,428,167 | $165,392,037 | 785,578 | 21.57% | $37.35 | 13F |
| MA | MASTERCARD INCORPORATED | 0.79% | 295,671 | $155,691,478 | -211,000 | -41.64% | $526.57 | 13F |
| EDU | NEW ORIENTAL ED & TECHNOLOGY | 0.77% | 2,359,150 | $151,410,247 | -174,450 | -6.89% | $64.18 | 13F |
| BBIO | BRIDGEBIO PHARMA INC | 0.58% | 4,195,000 | $115,110,800 | 2,448,000 | 140.13% | $27.44 | 13F |
| MRNA | MODERNA INC (Put) | 0.55% | 2,620,800 | $108,972,864 | -879,200 | -25.12% | $41.58 | 13F |
| MASI | MASIMO CORP | 0.33% | 397,000 | $65,624,100 | -861,563 | -68.46% | $165.3 | 13F |
| CNTA | CENTESSA PHARMACEUTICALS PLC | 0.3% | 3,498,709 | $58,603,376 | 684,391 | 24.32% | $16.75 | 13F |
| HR | HEALTHCARE RLTY TR | 0.28% | 3,264,000 | $55,324,800 | 661,000 | 25.39% | $16.95 | 13F |
| ZTO | ZTO EXPRESS CAYMAN INC (PRN) | 0.28% | 54,930,000 | $54,598,064 | -20,070,000 | -26.76% | $0.99 | 13F |
| WAY | WAYSTAR HLDG CORP | 0.25% | 1,342,000 | $49,251,400 | 1,342,000 | New | $36.7 | 13F |
| SPY | SPDR S&P 500 ETF TR | 0.24% | 82,000 | $48,058,560 | 82,000 | New | $586.08 | 13F |
| EHC | ENCOMPASS HEALTH CORP | 0.22% | 461,000 | $42,573,350 | 458,000 | 15266.7% | $92.35 | 13F |
| LQDA | LIQUIDIA CORPORATION | 0.2% | 3,290,956 | $38,701,643 | | No Change | $11.76 | 13F |
| GDS | GDS HLDGS LTD | 0.18% | 1,531,133 | $36,379,720 | | No Change | $23.76 | 13F |
| TECX | TECTONIC THERAPEUTIC INC | 0.17% | 713,050 | $32,921,519 | 192,653 | 37.02% | $46.17 | 13F |
| CAPR | CAPRICOR THERAPEUTICS INC | 0.16% | 2,250,400 | $31,055,520 | 2,250,400 | New | $13.8 | 13F |
| ASHR | DBX ETF TR (Call) | 0.14% | 1,020,000 | $26,999,400 | 1,020,000 | New | $26.47 | 13F |
| FLUT | FLUTTER ENTMT PLC | 0.12% | 90,300 | $23,338,035 | 37,030 | 69.51% | $258.45 | 13F |
| GXO | GXO LOGISTICS INCORPORATED | 0.11% | 513,400 | $22,332,900 | 513,400 | New | $43.5 | 13F |
| SVRA | SAVARA INC | 0.11% | 6,835,000 | $20,983,450 | 2,275,000 | 49.89% | $3.07 | 13F |
| SIMO | SILICON MOTION TECHNOLOGY CO | 0.11% | 415,000 | $22,430,750 | -99,000 | -19.26% | $54.05 | 13F |
| ZYME | ZYMEWORKS INC | 0.1% | 1,329,974 | $19,470,819 | -31,026 | -2.28% | $14.64 | 13F |
| LTM | LATAM AIRLINES GROUP SA | 0.09% | 618,469 | $17,057,375 | 318,092 | 105.9% | $27.58 | 13F |
| WGS | GENEDX HOLDINGS CORP | 0.08% | 195,000 | $14,987,700 | 195,000 | New | $76.86 | 13F |
| TYRA | TYRA BIOSCIENCES INC | 0.07% | 1,000,981 | $13,913,636 | 1,000,981 | New | $13.9 | 13F |
| VYGR | VOYAGER THERAPEUTICS INC | 0.07% | 2,570,700 | $14,575,869 | 278,700 | 12.16% | $5.67 | 13F |
| ARWR | ARROWHEAD PHARMACEUTICALS IN | 0.06% | 628,800 | $11,821,440 | 628,800 | New | $18.8 | 13F |
| ENTA | ENANTA PHARMACEUTICALS INC | 0.06% | 2,108,262 | $12,122,507 | | No Change | $5.75 | 13F |
| NUVL | NUVALENT INC | 0.06% | 150,000 | $11,742,000 | | No Change | $78.28 | 13F |
| TNGX | TANGO THERAPEUTICS INC | 0.06% | 4,000,000 | $12,360,000 | 4,000,000 | New | $3.09 | 13F |
| GEHC | GE HEALTHCARE TECHNOLOGIES I | 0.05% | 124,000 | $9,694,320 | 124,000 | New | $78.18 | 13F |
| MARA | MARA HOLDINGS INC | 0.05% | 555,000 | $9,307,350 | 555,000 | New | $16.77 | 13F |
| BDSX | BIODESIX INC | 0.03% | 3,811,426 | $5,831,482 | -825,365 | -17.8% | $1.53 | 13F |
| DYN | DYNE THERAPEUTICS INC | 0.03% | 229,121 | $5,398,091 | -198,879 | -46.47% | $23.56 | 13F |
| HLXB | HELIX ACQUISITION CORP II | 0.03% | 600,000 | $6,300,000 | | No Change | $10.5 | 13F |
| GRNDWS | GRINDR INC | 0.02% | 540,000 | $3,645,000 | | No Change | $6.75 | 13F |
| SLNO | SOLENO THERAPEUTICS INC | 0.02% | 90,000 | $4,045,500 | 90,000 | New | $44.95 | 13F |
| VNET | VNET GROUP INC | 0.02% | 650,000 | $3,081,000 | | No Change | $4.74 | 13F |
| MTAL | MAC COPPER LIMITED | 0.02% | 330,901 | $3,514,169 | -79,296 | -19.33% | $10.62 | 13F |
| ELEV | ELEVATION ONCOLOGY INC | 0.01% | 3,527,482 | $1,984,561 | | No Change | $0.56 | 13F |
| JANX | JANUX THERAPEUTICS INC | 0.01% | 48,000 | $2,569,920 | 48,000 | New | $53.54 | 13F |
| PRME | PRIME MEDICINE INC | 0.01% | 750,000 | $2,190,000 | | No Change | $2.92 | 13F |
| SMC | SUMMIT MIDSTREAM CORPORATION | 0.01% | 58,214 | $2,199,325 | | No Change | $37.78 | 13F |
| ALVO | ALVOTECH | 0.01% | 199,675 | $2,641,700 | | No Change | $13.23 | 13F |
| GATE | MARBLEGATE ACQUISITION CORP | 0.00836% | 150,000 | $1,648,500 | | No Change | $10.99 | 13F |
| MDGL | MADRIGAL PHARMACEUTICALS INC | 0.00519% | 3,319 | $1,024,144 | | No Change | $308.57 | 13F |
| CARA | CARA THERAPEUTICS INC | 0.00403% | 129,685 | $793,672 | 129,685 | New | $6.12 | 13F |
| FBRX | FORTE BIOSCIENCES INC | 0.00403% | 35,000 | $794,850 | -37,413 | -51.67% | $22.71 | 13F |
| ROIV | ROIVANT SCIENCES LTD | 0.00222% | 37,000 | $437,710 | | No Change | $11.83 | 13F |
| GKOS | GLAUKOS CORP | 0.00198% | 2,600 | $389,844 | | No Change | $149.94 | 13F |
| BTSG | BRIGHTSPRING HEALTH SVCS INC | 0.0019% | 22,000 | $374,660 | | No Change | $17.03 | 13F |
| ARQT | ARCUTIS BIOTRAPEUTICS INC | 0.00184% | 26,000 | $362,180 | | No Change | $13.93 | 13F |
| TWST | TWIST BIOSCIENCE CORP | 0.0018% | 7,650 | $355,496 | -333,000 | -97.75% | $46.47 | 13F |
| UTHR | UNITED THERAPEUTICS CORP DEL | 0.00179% | 1,000 | $352,840 | | No Change | $352.84 | 13F |
| BPMC | BLUEPRINT MEDICINES CORP | 0.00177% | 4,000 | $348,880 | | No Change | $87.22 | 13F |
| AXSM | AXSOME THERAPEUTICS INC | 0.00172% | 4,000 | $338,440 | | No Change | $84.61 | 13F |
| KRYS | KRYSTAL BIOTECH INC | 0.00159% | 2,000 | $313,320 | | No Change | $156.66 | 13F |
| PGNY | PROGYNY INC | 0.00157% | 18,000 | $310,500 | -913,307 | -98.07% | $17.25 | 13F |
| ACLX | ARCELLX INC | 0.00156% | 4,000 | $306,760 | | No Change | $76.69 | 13F |
| SRRK | SCHOLAR ROCK HLDG CORP | 0.00153% | 7,000 | $302,540 | 7,000 | New | $43.22 | 13F |
| HCA | HCA HEALTHCARE INC | 0.00152% | 1,000 | $300,150 | | No Change | $300.15 | 13F |
| GMED | GLOBUS MED INC | 0.00151% | 3,600 | $297,756 | | No Change | $82.71 | 13F |
| IMVT | IMMUNOVANT INC | 0.00151% | 12,000 | $297,240 | | No Change | $24.77 | 13F |
| BRKR | BRUKER CORP | 0.00149% | 5,000 | $293,100 | -27,000 | -84.38% | $58.62 | 13F |
| MMSI | MERIT MED SYS INC | 0.00147% | 3,000 | $290,160 | | No Change | $96.72 | 13F |
| HQY | HEALTHEQUITY INC | 0.00136% | 2,800 | $268,660 | | No Change | $95.95 | 13F |
| PACB | PACIFIC BIOSCIENCES CALIF IN | 0.00125% | 135,000 | $247,050 | | No Change | $1.83 | 13F |
| SBRA | SABRA HEALTH CARE REIT INC | 0.00123% | 14,000 | $242,480 | | No Change | $17.32 | 13F |
| SAGE | SAGE THERAPEUTICS INC | 0.00118% | 42,800 | $232,404 | | No Change | $5.43 | 13F |
| COR | CENCORA INC | 0.00114% | 1,000 | $224,680 | -234,200 | -99.57% | $224.68 | 13F |
| EW | EDWARDS LIFESCIENCES CORP | 0.00113% | 3,000 | $222,090 | 3,000 | New | $74.03 | 13F |
| ICUI | ICU MED INC | 0.0011% | 1,400 | $217,238 | | No Change | $155.17 | 13F |
| CHE | CHEMED CORP NEW | 0.00107% | 400 | $211,920 | | No Change | $529.8 | 13F |
| GRFS | GRIFOLS S A | 0.00106% | 28,000 | $208,320 | | No Change | $7.44 | 13F |
| ICLR | ICON PLC | 0.00106% | 1,000 | $209,710 | -219,800 | -99.55% | $209.71 | 13F |
| INSM | INSMED INC | 0.00105% | 3,000 | $207,120 | | No Change | $69.04 | 13F |
| ONC | BEIGENE LTD | 0.00103% | 1,100 | $203,181 | | No Change | $184.71 | 13F |
| ALT | ALTIMMUNE INC | 0.00101% | 27,600 | $198,996 | | No Change | $7.21 | 13F |
| ELAN | ELANCO ANIMAL HEALTH INC | 0.00098% | 16,000 | $193,760 | | No Change | $12.11 | 13F |
| IOVA | IOVANCE BIOTRAPEUTICS INC | 0.00098% | 26,000 | $192,400 | | No Change | $7.4 | 13F |
| SLDPW | SOLID POWER INC | 0.00092% | 405,316 | $182,392 | | No Change | $0.45 | 13F |
| EVH | EVOLENT HEALTH INC | 0.0008% | 14,000 | $157,500 | -625,000 | -97.81% | $11.25 | 13F |
| GERN | GERON CORP | 0.00077% | 43,000 | $152,220 | | No Change | $3.54 | 13F |
| FOLD | AMICUS THERAPEUTICS INC | 0.00076% | 16,000 | $150,720 | | No Change | $9.42 | 13F |
| OSCR | OSCAR HEALTH INC | 0.00075% | 11,000 | $147,840 | | No Change | $13.44 | 13F |
| ANNAW | ALEANNA INC | 0.0007% | 990,000 | $138,600 | 990,000 | New | $0.14 | 13F |
| COGT | COGENT BIOSCIENCES INC | 0.00067% | 17,000 | $132,600 | | No Change | $7.8 | 13F |
| SNDX | SYNDAX PHARMACEUTICALS INC | 0.00067% | 10,000 | $132,200 | | No Change | $13.22 | 13F |
| NVAX | NOVAVAX INC | 0.00065% | 16,000 | $128,640 | | No Change | $8.04 | 13F |
| ARDX | ARDELYX INC | 0.00059% | 23,000 | $116,610 | | No Change | $5.07 | 13F |
| CCCC | C4 THERAPEUTICS INC | 0.00051% | 28,000 | $100,800 | | No Change | $3.6 | 13F |
| CGC | CANOPY GROWTH CORP | 0.00042% | 30,000 | $82,200 | | No Change | $2.74 | 13F |
| BYND | BEYOND MEAT INC | 0.00036% | 19,000 | $71,440 | 19,000 | New | $3.76 | 13F |
| IRWD | IRONWOOD PHARMACEUTICALS INC | 0.00029% | 13,000 | $57,590 | | No Change | $4.43 | 13F |
| ANNA | ALEANNA INC | 0.00025% | 78,400 | $48,670 | 78,400 | New | $0.62 | 13F |
| GATEW | MARBLEGATE ACQUISITION CORP | 0.00024% | 1,485,000 | $48,263 | | No Change | $0.03 | 13F |
| CITEW | CARTICA ACQUISITION CORP | 0.00024% | 175,000 | $47,250 | | No Change | $0.27 | 13F |
| NVNIW | NVNI GROUP LIMITED | 0.00013% | 375,000 | $24,825 | | No Change | $0.07 | 13F |
| RVMDW | REVOLUTION MEDICINES INC | 0.0001% | 120,085 | $19,406 | | No Change | $0.16 | 13F |
| AMGN | AMGEN INC | | | | -47,000 | Exited | | 13F |
| AMLX | AMYLYX PHARMACEUTICALS INC | | | | -1,150,221 | Exited | | 13F |
| ANAB | ANAPTYSBIO INC | | | | -183,876 | Exited | | 13F |
| ASND | ASCENDIS PHARMA A/S | | | | -1,400 | Exited | | 13F |
| RNA | AVIDITY BIOSCIENCES INC | | | | -5,000 | Exited | | 13F |
| AXNX | AXONICS INC | | | | -517,000 | Exited | | 13F |
| CARA | CARA THERAPEUTICS INC | | | | -1,556,251 | Exited | | 13F |
| CTLT | CATALENT INC | | | | -8,394,000 | Exited | | 13F |
| HWM | HOWMET AEROSPACE INC | | | | -1,514,339 | Exited | | 13F |
| IWM | ISHARES TR (Put) | | | | -1,000,000 | Exited | | 13F |
| BEKE | KE HLDGS INC | | | | -4,740,833 | Exited | | 13F |
| LBRDK | LIBERTY BROADBAND CORP | | | | -660,000 | Exited | | 13F |
| BYND | BEYOND MEAT INC | | | | -19,000 | Exited | | 13F |
| CNC | CENTENE CORP DEL | | | | -614,917 | Exited | | 13F |
| CYTK | CYTOKINETICS INC | | | | -102,400 | Exited | | 13F |
| GHIXW | GORES HOLDINGS IX INC | | | | -166,664 | Exited | | 13F |
| LBPH | LONGBOARD PHARMACEUTICALS IN | | | | -3,150,857 | Exited | | 13F |
| LU | LUFAX HOLDING LTD | | | | -15,000 | Exited | | 13F |
| MGX | METAGENOMI INC | | | | -1,057,201 | Exited | | 13F |
| RGTIW | RIGETTI COMPUTING INC | | | | -22,675 | Exited | | 13F |
| RCM | R1 RCM INC | | | | -16,000 | Exited | | 13F |
| SPGI | S&P GLOBAL INC | | | | -475,334 | Exited | | 13F |
| NOW | SERVICENOW INC | | | | -295,050 | Exited | | 13F |
| SHW | SHERWIN WILLIAMS CO | | | | -555,950 | Exited | | 13F |
| SWN | SOUTHWESTERN ENERGY CO | | | | -25,993,099 | Exited | | 13F |
| SQSP | SQUARESPACE INC | | | | -2,891,632 | Exited | | 13F |
| SRCL | STERICYCLE INC | | | | -3,146,000 | Exited | | 13F |
| RUN | SUNRUN INC (PRN) | | | | -103,223,000 | Exited | | 13F |
| TAL | TAL EDUCATION GROUP | | | | -1,365,000 | Exited | | 13F |
| THC | TENET HEALTHCARE CORP | | | | -692,442 | Exited | | 13F |
| TMDX | TRANSMEDICS GROUP INC | | | | -44,000 | Exited | | 13F |
| RARE | ULTRAGENYX PHARMACEUTICAL IN | | | | -4,000 | Exited | | 13F |
| PCVX | VAXCYTE INC | | | | -28,000 | Exited | | 13F |
| VTYX | VENTYX BIOSCIENCES INC | | | | -3,170,000 | Exited | | 13F |
| BCSAW | BLOCKCHAIN COINVSTRS ACQ CRP | | | | -150,000 | Exited | | 13F |
| JWSMWS | JAWS MUSTANG ACQUISITION COR | | | | -200,000 | Exited | | 13F |
| IVCP | SWIFTMERGE ACQUISITION CORP | | | | -300,000 | Exited | | 13F |
| IVCPW | SWIFTMERGE ACQUISITION CORP | | | | -990,000 | Exited | | 13F |
| RCFAWS | PERCEPTION CAPITAL CORP IV | | | | -300,000 | Exited | | 13F |
| SEDAWS | SDCL EDGE ACQUISITION CORP | | | | -866,250 | Exited | | 13F |
