| Symbol | Company | Owner | Relationship | Date | Transaction | Cost | # Shares | Value ($) | Total Shares | Filing | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SAGE | Sage Therapeutics, Inc. | Greene Barry E | President and CEO | Nov 10, 2022 | Buy | $34.48 | 14,500 | 500,022 | 46,940 | Nov 15, 2022, 04:04 PM | |
| KPTI | Karyopharm Therapeutics Inc. | Greene Barry E | Director | Aug 11, 2022 | Option Exercise | $1.49 | 7,576 | 11,250 | 13,606 | Aug 15, 2022, 08:05 AM | |
| SAGE | Sage Therapeutics, Inc. | Greene Barry E | President and CEO | Aug 05, 2021 | Buy | $43.15 | 23,640 | 1,020,054 | 32,440 | Aug 09, 2021, 09:07 AM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President | Sep 09, 2020 | Sale | $66.19 | 89,060 | 5,894,599 | 114,873 | Sep 11, 2020, 05:11 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President | Aug 10, 2020 | Option Exercise | $70.95 | 4,931 | 349,871 | 67,167 | Aug 11, 2020, 04:09 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President | Jul 07, 2020 | Option Exercise | $84.57 | 44,530 | 3,765,680 | 84,501 | Jul 09, 2020, 04:02 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President | May 06, 2020 | Option Exercise | $79.57 | 44,530 | 3,543,030 | 84,501 | May 07, 2020, 04:09 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President | Apr 07, 2020 | Option Exercise | $104.82 | 1,663 | 174,321 | 62,300 | Apr 09, 2020, 04:06 PM | |
| KPTI | Karyopharm Therapeutics Inc. | Greene Barry E | Director | Mar 13, 2020 | Option Exercise | $0.03 | 3,030 | 100 | 6,030 | Mar 17, 2020, 05:35 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President | Oct 22, 2019 | Sale | $53.21 | 117,826 | 6,269,521 | 111,851 | Oct 24, 2019, 04:04 PM | |
| ACOR | ACORDA THERAPEUTICS INC | Greene Barry E | Director | May 21, 2018 | Option Exercise | $21.53 | 18,727 | 403,194 | 10,000 | May 23, 2018, 07:35 AM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President | Mar 14, 2018 | Sale | $143.10 | 38,460 | 5,503,736 | 97,544 | Mar 16, 2018, 05:05 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President | Oct 02, 2017 | Option Exercise | $73.18 | 170,632 | 12,485,997 | 185,744 | Oct 04, 2017, 07:45 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President | Sep 20, 2017 | Option Exercise | $65.69 | 153,630 | 10,092,723 | 165,399 | Sep 22, 2017, 05:05 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President | Sep 21, 2017 | Option Exercise | $12.33 | 11,844 | 146,042 | 100,428 | Sep 22, 2017, 05:05 PM | |
| ACOR | ACORDA THERAPEUTICS INC | Greene Barry E | Director | Aug 01, 2017 | Option Exercise | $19.89 | 20,000 | 397,797 | 10,000 | Aug 03, 2017, 04:06 PM | |
| ACOR | ACORDA THERAPEUTICS INC | Greene Barry E | Director | Feb 09, 2017 | Option Exercise | $22.39 | 1,446 | 32,376 | 723 | Feb 13, 2017, 04:14 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President | Dec 01, 2016 | Sale | $30.12 | 87,430 | 2,633,141 | 120,409 | Dec 05, 2016, 04:55 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | Mar 24, 2016 | Option Exercise | $8.20 | 16,540 | 135,672 | 64,804 | Mar 28, 2016, 05:27 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | Aug 04, 2015 | Option Exercise | $18.73 | 26,972 | 505,124 | 50,364 | Aug 06, 2015, 05:32 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | May 26, 2015 | Option Exercise | $69.06 | 134,758 | 9,306,387 | 90,771 | May 28, 2015, 04:16 PM | |
| KPTI | Karyopharm Therapeutics Inc. | Greene Barry E | Director | Apr 02, 2015 | Buy | $29.31 | 3,000 | 87,938 | 3,000 | Apr 06, 2015, 05:57 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | Dec 22, 2014 | Option Exercise | $13.12 | 1,000 | 13,120 | 23,392 | Dec 22, 2014, 05:30 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | Dec 19, 2014 | Sale | $100.00 | 11,200 | 1,120,000 | 22,392 | Dec 22, 2014, 05:30 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | Nov 17, 2014 | Sale | $48.21 | 66,400 | 3,200,876 | 66,792 | Nov 19, 2014, 05:52 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | Nov 11, 2014 | Sale | $53.39 | 22,200 | 1,185,258 | 44,692 | Nov 13, 2014, 05:05 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | Feb 03, 2014 | Option Exercise | $12.48 | 21,180 | 264,392 | 35,272 | Feb 04, 2014, 05:41 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | Dec 17, 2013 | Option Exercise | $6.78 | 11,200 | 75,936 | 15,772 | Dec 18, 2013, 06:34 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | May 28, 2013 | Option Exercise | $15.47 | 45,644 | 706,341 | 19,500 | May 30, 2013, 06:04 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President & COO | Mar 14, 2013 | Option Exercise | $12.97 | 48,116 | 624,305 | 28,630 | Mar 18, 2013, 06:07 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | Mar 08, 2013 | Option Exercise | $12.69 | 48,000 | 609,070 | 28,572 | Mar 11, 2013, 06:39 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | Feb 21, 2012 | Buy | $10.75 | 1,860 | 19,995 | 4,572 | Feb 23, 2012, 04:53 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | Jan 09, 2012 | Buy | $8.80 | 567 | 4,992 | 2,712 | Jan 11, 2012, 04:58 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | Dec 12, 2011 | Buy | $7.15 | 699 | 4,995 | 2,145 | Dec 14, 2011, 04:37 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | Nov 14, 2011 | Buy | $7.09 | 704 | 4,994 | 1,446 | Nov 16, 2011, 04:42 PM | |
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | Greene Barry E | President and COO | Oct 11, 2011 | Buy | $6.73 | 742 | 4,996 | 742 | Oct 13, 2011, 05:09 PM |
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