Insider Transactions for GLAUKOS Corp (GKOS)

Owner Relationship Date Transaction Cost # Shares Value($) Total Shares Form 4
Burns Thomas William Chief Executive Officer Sep 07, 2017 Option Exercise $1.70 73,788 125,167 284,028 Sep 08, 2017, 05:39 PM
Burns Thomas William Chief Executive Officer Sep 07, 2017 Sale $41.36 73,788 3,051,872 210,240 Sep 08, 2017, 05:39 PM
Burns Thomas William Chief Executive Officer Sep 05, 2017 Option Exercise $1.92 1,212 2,333 211,452 Sep 06, 2017, 08:17 PM
Burns Thomas William Chief Executive Officer Sep 05, 2017 Sale $41.25 1,212 49,995 210,240 Sep 06, 2017, 08:17 PM
ORBIMED ADVISORS LLC Director Aug 31, 2017 Sale $37.82 44,922 1,698,950 1,358,833 Sep 05, 2017, 09:27 PM
ORBIMED ADVISORS LLC Director Sep 05, 2017 Sale $39.09 425,200 16,621,730 1,076,444 Sep 05, 2017, 09:27 PM
ORBIMED ADVISORS LLC Director Sep 01, 2017 Sale $37.72 110,078 4,152,142 1,249,793 Sep 05, 2017, 09:27 PM
SILVERSTEIN JONATHAN Director Sep 05, 2017 Sale $39.09 425,200 16,621,730 1,076,444 Sep 05, 2017, 09:21 PM
SILVERSTEIN JONATHAN Director Sep 01, 2017 Sale $37.72 110,078 4,152,142 1,249,793 Sep 05, 2017, 09:21 PM
SILVERSTEIN JONATHAN Director Aug 31, 2017 Sale $37.82 44,922 1,698,950 1,358,833 Sep 05, 2017, 09:21 PM
SILVERSTEIN JONATHAN Director Aug 17, 2017 Sale $37.85 226,920 8,588,922 1,403,331 Aug 17, 2017, 05:27 PM
SILVERSTEIN JONATHAN Director Aug 16, 2017 Sale $38.01 65,580 2,492,696 1,628,111 Aug 17, 2017, 05:27 PM
SILVERSTEIN JONATHAN Director Aug 15, 2017 Sale $38.29 32,500 1,244,425 1,693,072 Aug 17, 2017, 05:27 PM
ORBIMED ADVISORS LLC Director Aug 16, 2017 Sale $38.01 65,580 2,492,696 1,628,111 Aug 17, 2017, 05:20 PM
ORBIMED ADVISORS LLC Director Aug 15, 2017 Sale $38.29 32,500 1,244,425 1,693,072 Aug 17, 2017, 05:20 PM
ORBIMED ADVISORS LLC Director Aug 17, 2017 Sale $37.85 226,920 8,588,922 1,403,331 Aug 17, 2017, 05:20 PM
SILVERSTEIN JONATHAN Director Mar 10, 2017 Sale $45.98 97,028 4,461,347 2,008,071 Mar 14, 2017, 07:47 PM
SILVERSTEIN JONATHAN Director Mar 14, 2017 Sale $44.54 74,100 3,300,414 1,725,265 Mar 14, 2017, 07:47 PM
SILVERSTEIN JONATHAN Director Mar 13, 2017 Sale $45.30 211,410 9,577,454 1,799,359 Mar 14, 2017, 07:47 PM
ORBIMED ADVISORS LLC Director Mar 14, 2017 Sale $44.54 74,100 3,300,414 1,725,265 Mar 14, 2017, 07:39 PM
ORBIMED ADVISORS LLC Director Mar 13, 2017 Sale $45.30 211,410 9,577,454 1,799,359 Mar 14, 2017, 07:39 PM
ORBIMED ADVISORS LLC Director Mar 10, 2017 Sale $45.98 97,028 4,461,347 2,008,071 Mar 14, 2017, 07:39 PM
SILVERSTEIN JONATHAN Director Mar 03, 2017 Sale $47.05 55,772 2,624,073 2,104,184 Mar 07, 2017, 06:52 PM
ORBIMED ADVISORS LLC Director Mar 03, 2017 Sale $47.05 55,772 2,624,073 2,104,184 Mar 07, 2017, 06:48 PM
Burns Thomas William Chief Executive Officer Feb 02, 2017 Sale $42.58 50,000 2,129,000 210,240 Feb 03, 2017, 04:11 PM
HARRISON RICHARD L CFO & Treasurer Jan 13, 2017 Option Exercise $7.28 6,313 45,927 7,701 Jan 13, 2017, 05:04 PM
HARRISON RICHARD L CFO & Treasurer Jan 12, 2017 Option Exercise $7.28 14,321 104,185 15,709 Jan 13, 2017, 05:04 PM
HARRISON RICHARD L CFO & Treasurer Jan 12, 2017 Sale $40.00 14,321 572,840 1,388 Jan 13, 2017, 05:04 PM
HARRISON RICHARD L CFO & Treasurer Jan 13, 2017 Sale $40.01 6,313 252,583 1,388 Jan 13, 2017, 05:04 PM
Calcaterra Chris M. Chief Commercial Officer Jan 13, 2017 Option Exercise $7.28 3,723 27,085 243,723 Jan 13, 2017, 05:04 PM
Calcaterra Chris M. Chief Commercial Officer Jan 12, 2017 Option Exercise $7.28 14,413 104,855 254,413 Jan 13, 2017, 05:04 PM
Calcaterra Chris M. Chief Commercial Officer Jan 12, 2017 Sale $40.00 14,413 576,520 240,000 Jan 13, 2017, 05:04 PM
Calcaterra Chris M. Chief Commercial Officer Jan 13, 2017 Sale $40.03 3,723 149,032 240,000 Jan 13, 2017, 05:04 PM
Burns Thomas William Chief Executive Officer Jan 09, 2017 Sale $37.60 40,000 1,504,000 260,240 Jan 11, 2017, 04:31 PM
Calcaterra Chris M. Chief Commercial Officer Jan 09, 2017 Option Exercise $7.28 20,000 145,500 260,000 Jan 11, 2017, 04:30 PM
Calcaterra Chris M. Chief Commercial Officer Jan 09, 2017 Sale $38.02 20,000 760,400 240,000 Jan 11, 2017, 04:30 PM
HARRISON RICHARD L CFO & Treasurer Jan 06, 2017 Option Exercise $4.63 20,634 95,603 22,022 Jan 09, 2017, 04:00 PM
HARRISON RICHARD L CFO & Treasurer Jan 06, 2017 Sale $35.58 20,634 734,142 1,448 Jan 09, 2017, 04:00 PM
Burns Thomas William Chief Executive Officer Dec 14, 2016 Option Exercise $1.25 8,000 10,000 299,388 Dec 16, 2016, 04:17 PM
LINK WILLIAM J PHD Director Nov 17, 2016 Sale $33.78 30,000 1,013,400 87,695 Nov 18, 2016, 04:23 PM
Burns Thomas William Chief Executive Officer Nov 14, 2016 Option Exercise $1.68 190,120 319,055 490,120 Nov 15, 2016, 04:59 PM
Burns Thomas William Chief Executive Officer Nov 15, 2016 Sale $34.03 10,000 340,300 290,000 Nov 15, 2016, 04:59 PM
Burns Thomas William Chief Executive Officer Nov 14, 2016 Sale $33.66 190,120 6,399,557 303,605 Nov 15, 2016, 04:59 PM
Calcaterra Chris M. Chief Commercial Officer Oct 24, 2016 Option Exercise $7.28 20,000 145,500 260,000 Oct 25, 2016, 04:55 PM
Calcaterra Chris M. Chief Commercial Officer Oct 24, 2016 Sale $36.01 20,000 720,200 240,000 Oct 25, 2016, 04:55 PM
Calcaterra Chris M. Chief Commercial Officer Oct 20, 2016 Option Exercise $7.28 40,000 291,000 280,000 Oct 20, 2016, 06:37 PM
Calcaterra Chris M. Chief Commercial Officer Oct 20, 2016 Sale $34.76 40,000 1,390,570 243,000 Oct 20, 2016, 06:37 PM
ORBIMED ADVISORS LLC Director Aug 12, 2016 Sale $33.72 14,100 475,452 2,159,430 Aug 12, 2016, 08:35 PM
ORBIMED ADVISORS LLC Director Aug 11, 2016 Sale $33.63 160,900 5,411,067 2,173,397 Aug 12, 2016, 08:35 PM
ORBIMED ADVISORS LLC Director Aug 10, 2016 Sale $33.77 117,938 3,982,766 2,332,779 Aug 12, 2016, 08:35 PM
SILVERSTEIN JONATHAN Director Aug 12, 2016 Sale $33.72 14,100 475,452 2,159,430 Aug 12, 2016, 08:22 PM
SILVERSTEIN JONATHAN Director Aug 11, 2016 Sale $33.63 160,900 5,411,067 2,173,397 Aug 12, 2016, 08:22 PM
SILVERSTEIN JONATHAN Director Aug 10, 2016 Sale $33.77 117,938 3,982,766 2,332,779 Aug 12, 2016, 08:22 PM
SILVERSTEIN JONATHAN Director Aug 03, 2016 Sale $30.59 425,000 13,000,750 2,449,604 Aug 05, 2016, 04:11 PM
ORBIMED ADVISORS LLC Director Aug 03, 2016 Sale $30.59 425,000 13,000,750 2,449,604 Aug 05, 2016, 04:05 PM
HARRISON RICHARD L Treasurer, CFO & Secretary Jul 27, 2016 Option Exercise $3.97 10,000 39,750 11,388 Jul 27, 2016, 06:54 PM
HARRISON RICHARD L Treasurer, CFO & Secretary Jul 27, 2016 Sale $35.01 10,000 350,100 1,388 Jul 27, 2016, 06:54 PM
Burns Thomas William Chief Executive Officer Jul 12, 2016 Sale $30.00 10,500 315,000 451,754 Jul 13, 2016, 05:10 PM
Burns Thomas William Chief Executive Officer Jul 13, 2016 Sale $30.07 151,754 4,563,243 300,000 Jul 13, 2016, 05:10 PM
HARRISON RICHARD L Treasurer, CFO & Secretary Jul 12, 2016 Option Exercise $3.97 5,700 22,657 7,088 Jul 13, 2016, 04:01 PM
HARRISON RICHARD L Treasurer, CFO & Secretary Jul 12, 2016 Sale $30.00 5,700 171,000 1,388 Jul 13, 2016, 04:01 PM
Burns Thomas William Chief Executive Officer Jul 01, 2016 Sale $29.12 50,000 1,456,000 462,254 Jul 05, 2016, 04:05 PM
Burns Thomas William Chief Executive Officer Jun 20, 2016 Sale $30.00 7,997 239,910 512,254 Jun 21, 2016, 04:25 PM
HARRISON RICHARD L Treasurer, CFO & Secretary Jun 20, 2016 Option Exercise $3.97 4,300 17,092 5,688 Jun 21, 2016, 04:24 PM
HARRISON RICHARD L Treasurer, CFO & Secretary Jun 20, 2016 Sale $30.00 4,300 129,000 1,388 Jun 21, 2016, 04:24 PM
Calcaterra Chris M. Chief Commercial Officer Jun 15, 2016 Option Exercise $5.02 45,464 228,271 285,464 Jun 16, 2016, 05:13 PM
Calcaterra Chris M. Chief Commercial Officer Jun 15, 2016 Sale $28.46 45,464 1,293,905 240,000 Jun 16, 2016, 05:13 PM
Burns Thomas William Chief Executive Officer Jun 06, 2016 Sale $25.16 24,578 618,382 520,251 Jun 06, 2016, 04:07 PM
Burns Thomas William Chief Executive Officer Jun 03, 2016 Sale $25.00 422 10,550 544,829 Jun 03, 2016, 04:59 PM
LINK WILLIAM J PHD Director May 31, 2016 Sale $23.98 34,058 816,711 109,395 Jun 02, 2016, 09:19 PM
VERSANT VENTURES I LLC Former 10 % owner May 31, 2016 Sale $23.98 34,058 816,711 109,395 Jun 02, 2016, 09:16 PM
VERSANT VENTURES I LLC Former 10 % owner May 31, 2016 Sale $23.98 34,058 816,711 109,395 Jun 02, 2016, 09:15 PM
Burns Thomas William Chief Executive Officer Jun 01, 2016 Sale $23.90 25,000 597,500 545,251 Jun 02, 2016, 04:11 PM
Burns Thomas William Chief Executive Officer May 25, 2016 Sale $25.00 300 7,500 570,251 May 26, 2016, 05:18 PM
HARRISON RICHARD L Treasurer, CFO & Secretary Dec 31, 2015 Option Exercise $15.30 1,388 21,236 4,656 May 06, 2016, 07:14 PM
Burns Thomas William Chief Executive Officer Dec 31, 2015 Option Exercise $15.30 1,388 21,236 1,388 May 06, 2016, 07:03 PM
Burns Thomas William Chief Executive Officer May 04, 2016 Sale $24.77 35,900 889,276 572,351 May 05, 2016, 04:01 PM
Burns Thomas William Chief Executive Officer May 03, 2016 Sale $20.00 800 16,000 606,451 May 05, 2016, 04:01 PM
Calcaterra Chris M. May 04, 2016 Option Exercise $3.97 68,000 270,300 308,000 May 05, 2016, 04:00 PM
Calcaterra Chris M. May 03, 2016 Sale $20.00 700 14,000 245,836 May 05, 2016, 04:00 PM
Calcaterra Chris M. May 04, 2016 Sale $24.44 73,836 1,804,427 256,885 May 05, 2016, 04:00 PM
WEISNER AIMEE S Director Mar 04, 2016 Buy $16.03 2,500 40,075 5,000 Mar 04, 2016, 02:32 PM
MONTREUX EQUITY PARTNERS IV LP 10% Owner Feb 25, 2016 Sale $16.16 70,000 1,131,200 3,209,812 Feb 26, 2016, 03:41 PM
Burns Thomas William Chief Executive Officer Dec 31, 2015 Buy $15.30 1,388 21,236 1,388 Jan 04, 2016, 03:04 PM
HARRISON RICHARD L Treasurer, CFO & Secretary Dec 31, 2015 Buy $15.30 1,388 21,236 4,656 Jan 04, 2016, 03:04 PM
WEISNER AIMEE S Director Nov 12, 2015 Buy $21.83 2,500 54,575 2,500 Nov 12, 2015, 04:31 PM
DOMAIN PARTNERS IV LP 10% Owner Jun 30, 2015 Option Exercise $18.00 8,700 156,600 2,068,960 Jul 01, 2015, 03:30 PM
DOMAIN PARTNERS IV LP 10% Owner Jun 30, 2015 Option Exercise $7.65 20,470 156,596 2,077,660 Jul 01, 2015, 03:30 PM
SILVERSTEIN JONATHAN Director Jun 30, 2015 Option Exercise $18.00 11,734 211,212 2,870,593 Jun 30, 2015, 06:13 PM
MORE ROBERT J Director Jun 24, 2015 Buy $18.00 5,000 90,000 5,000 Jun 30, 2015, 06:11 PM
LINK WILLIAM J PHD Director Jun 30, 2015 Option Exercise $18.00 11,736 211,248 2,884,835 Jun 30, 2015, 06:02 PM
LINK WILLIAM J PHD Director Jun 30, 2015 Option Exercise $18.00 235 4,230 56,696 Jun 30, 2015, 06:02 PM
LINK WILLIAM J PHD Director Jun 30, 2015 Option Exercise $18.00 551 9,918 132,483 Jun 30, 2015, 06:02 PM
LINK WILLIAM J PHD Director Jun 30, 2015 Option Exercise $18.00 246 4,428 62,217 Jun 30, 2015, 06:02 PM
ORBIMED ADVISORS LLC Director Jun 30, 2015 Option Exercise $18.00 11,734 211,212 2,870,593 Jun 30, 2015, 05:51 PM
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise $18.00 11,736 211,248 2,884,835 Jun 30, 2015, 05:43 PM
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise $18.00 235 4,230 56,696 Jun 30, 2015, 05:43 PM
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise $18.00 551 9,918 132,483 Jun 30, 2015, 05:43 PM
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise $18.00 246 4,428 62,217 Jun 30, 2015, 05:43 PM
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise $18.00 246 4,428 62,217 Jun 30, 2015, 05:42 PM
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise $18.00 11,736 211,248 2,884,835 Jun 30, 2015, 05:42 PM
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise $18.00 235 4,230 56,696 Jun 30, 2015, 05:42 PM
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise $18.00 551 9,918 132,483 Jun 30, 2015, 05:42 PM
Owner Relationship Date Transaction Value($)
Burns Thomas William Chief Executive Officer Sep 07, 2017 Option Exercise 125,167
Burns Thomas William Chief Executive Officer Sep 07, 2017 Sale 3,051,872
Burns Thomas William Chief Executive Officer Sep 05, 2017 Option Exercise 2,333
Burns Thomas William Chief Executive Officer Sep 05, 2017 Sale 49,995
ORBIMED ADVISORS LLC Director Aug 31, 2017 Sale 1,698,950
ORBIMED ADVISORS LLC Director Sep 05, 2017 Sale 16,621,730
ORBIMED ADVISORS LLC Director Sep 01, 2017 Sale 4,152,142
SILVERSTEIN JONATHAN Director Sep 05, 2017 Sale 16,621,730
SILVERSTEIN JONATHAN Director Sep 01, 2017 Sale 4,152,142
SILVERSTEIN JONATHAN Director Aug 31, 2017 Sale 1,698,950
SILVERSTEIN JONATHAN Director Aug 17, 2017 Sale 8,588,922
SILVERSTEIN JONATHAN Director Aug 16, 2017 Sale 2,492,696
SILVERSTEIN JONATHAN Director Aug 15, 2017 Sale 1,244,425
ORBIMED ADVISORS LLC Director Aug 16, 2017 Sale 2,492,696
ORBIMED ADVISORS LLC Director Aug 15, 2017 Sale 1,244,425
ORBIMED ADVISORS LLC Director Aug 17, 2017 Sale 8,588,922
SILVERSTEIN JONATHAN Director Mar 10, 2017 Sale 4,461,347
SILVERSTEIN JONATHAN Director Mar 14, 2017 Sale 3,300,414
SILVERSTEIN JONATHAN Director Mar 13, 2017 Sale 9,577,454
ORBIMED ADVISORS LLC Director Mar 14, 2017 Sale 3,300,414
ORBIMED ADVISORS LLC Director Mar 13, 2017 Sale 9,577,454
ORBIMED ADVISORS LLC Director Mar 10, 2017 Sale 4,461,347
SILVERSTEIN JONATHAN Director Mar 03, 2017 Sale 2,624,073
ORBIMED ADVISORS LLC Director Mar 03, 2017 Sale 2,624,073
Burns Thomas William Chief Executive Officer Feb 02, 2017 Sale 2,129,000
HARRISON RICHARD L CFO & Treasurer Jan 13, 2017 Option Exercise 45,927
HARRISON RICHARD L CFO & Treasurer Jan 12, 2017 Option Exercise 104,185
HARRISON RICHARD L CFO & Treasurer Jan 12, 2017 Sale 572,840
HARRISON RICHARD L CFO & Treasurer Jan 13, 2017 Sale 252,583
Calcaterra Chris M. Chief Commercial Officer Jan 13, 2017 Option Exercise 27,085
Calcaterra Chris M. Chief Commercial Officer Jan 12, 2017 Option Exercise 104,855
Calcaterra Chris M. Chief Commercial Officer Jan 12, 2017 Sale 576,520
Calcaterra Chris M. Chief Commercial Officer Jan 13, 2017 Sale 149,032
Burns Thomas William Chief Executive Officer Jan 09, 2017 Sale 1,504,000
Calcaterra Chris M. Chief Commercial Officer Jan 09, 2017 Option Exercise 145,500
Calcaterra Chris M. Chief Commercial Officer Jan 09, 2017 Sale 760,400
HARRISON RICHARD L CFO & Treasurer Jan 06, 2017 Option Exercise 95,603
HARRISON RICHARD L CFO & Treasurer Jan 06, 2017 Sale 734,142
Burns Thomas William Chief Executive Officer Dec 14, 2016 Option Exercise 10,000
LINK WILLIAM J PHD Director Nov 17, 2016 Sale 1,013,400
Burns Thomas William Chief Executive Officer Nov 14, 2016 Option Exercise 319,055
Burns Thomas William Chief Executive Officer Nov 15, 2016 Sale 340,300
Burns Thomas William Chief Executive Officer Nov 14, 2016 Sale 6,399,557
Calcaterra Chris M. Chief Commercial Officer Oct 24, 2016 Option Exercise 145,500
Calcaterra Chris M. Chief Commercial Officer Oct 24, 2016 Sale 720,200
Calcaterra Chris M. Chief Commercial Officer Oct 20, 2016 Option Exercise 291,000
Calcaterra Chris M. Chief Commercial Officer Oct 20, 2016 Sale 1,390,570
ORBIMED ADVISORS LLC Director Aug 12, 2016 Sale 475,452
ORBIMED ADVISORS LLC Director Aug 11, 2016 Sale 5,411,067
ORBIMED ADVISORS LLC Director Aug 10, 2016 Sale 3,982,766
SILVERSTEIN JONATHAN Director Aug 12, 2016 Sale 475,452
SILVERSTEIN JONATHAN Director Aug 11, 2016 Sale 5,411,067
SILVERSTEIN JONATHAN Director Aug 10, 2016 Sale 3,982,766
SILVERSTEIN JONATHAN Director Aug 03, 2016 Sale 13,000,750
ORBIMED ADVISORS LLC Director Aug 03, 2016 Sale 13,000,750
HARRISON RICHARD L Treasurer, CFO & Secretary Jul 27, 2016 Option Exercise 39,750
HARRISON RICHARD L Treasurer, CFO & Secretary Jul 27, 2016 Sale 350,100
Burns Thomas William Chief Executive Officer Jul 12, 2016 Sale 315,000
Burns Thomas William Chief Executive Officer Jul 13, 2016 Sale 4,563,243
HARRISON RICHARD L Treasurer, CFO & Secretary Jul 12, 2016 Option Exercise 22,657
HARRISON RICHARD L Treasurer, CFO & Secretary Jul 12, 2016 Sale 171,000
Burns Thomas William Chief Executive Officer Jul 01, 2016 Sale 1,456,000
Burns Thomas William Chief Executive Officer Jun 20, 2016 Sale 239,910
HARRISON RICHARD L Treasurer, CFO & Secretary Jun 20, 2016 Option Exercise 17,092
HARRISON RICHARD L Treasurer, CFO & Secretary Jun 20, 2016 Sale 129,000
Calcaterra Chris M. Chief Commercial Officer Jun 15, 2016 Option Exercise 228,271
Calcaterra Chris M. Chief Commercial Officer Jun 15, 2016 Sale 1,293,905
Burns Thomas William Chief Executive Officer Jun 06, 2016 Sale 618,382
Burns Thomas William Chief Executive Officer Jun 03, 2016 Sale 10,550
LINK WILLIAM J PHD Director May 31, 2016 Sale 816,711
VERSANT VENTURES I LLC Former 10 % owner May 31, 2016 Sale 816,711
VERSANT VENTURES I LLC Former 10 % owner May 31, 2016 Sale 816,711
Burns Thomas William Chief Executive Officer Jun 01, 2016 Sale 597,500
Burns Thomas William Chief Executive Officer May 25, 2016 Sale 7,500
HARRISON RICHARD L Treasurer, CFO & Secretary Dec 31, 2015 Option Exercise 21,236
Burns Thomas William Chief Executive Officer Dec 31, 2015 Option Exercise 21,236
Burns Thomas William Chief Executive Officer May 04, 2016 Sale 889,276
Burns Thomas William Chief Executive Officer May 03, 2016 Sale 16,000
Calcaterra Chris M. May 04, 2016 Option Exercise 270,300
Calcaterra Chris M. May 03, 2016 Sale 14,000
Calcaterra Chris M. May 04, 2016 Sale 1,804,427
WEISNER AIMEE S Director Mar 04, 2016 Buy 40,075
MONTREUX EQUITY PARTNERS IV LP 10% Owner Feb 25, 2016 Sale 1,131,200
Burns Thomas William Chief Executive Officer Dec 31, 2015 Buy 21,236
HARRISON RICHARD L Treasurer, CFO & Secretary Dec 31, 2015 Buy 21,236
WEISNER AIMEE S Director Nov 12, 2015 Buy 54,575
DOMAIN PARTNERS IV LP 10% Owner Jun 30, 2015 Option Exercise 156,600
DOMAIN PARTNERS IV LP 10% Owner Jun 30, 2015 Option Exercise 156,596
SILVERSTEIN JONATHAN Director Jun 30, 2015 Option Exercise 211,212
MORE ROBERT J Director Jun 24, 2015 Buy 90,000
LINK WILLIAM J PHD Director Jun 30, 2015 Option Exercise 211,248
LINK WILLIAM J PHD Director Jun 30, 2015 Option Exercise 4,230
LINK WILLIAM J PHD Director Jun 30, 2015 Option Exercise 9,918
LINK WILLIAM J PHD Director Jun 30, 2015 Option Exercise 4,428
ORBIMED ADVISORS LLC Director Jun 30, 2015 Option Exercise 211,212
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise 211,248
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise 4,230
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise 9,918
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise 4,428
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise 4,428
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise 211,248
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise 4,230
VERSANT VENTURES I LLC 10% Owner Jun 30, 2015 Option Exercise 9,918